SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4d8o'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2S_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 6 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.33A 1k2sA-4d8oA:
undetectable
1k2sB-4d8oA:
undetectable		 1k2sA-4d8oA:
20.07
1k2sB-4d8oA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2T_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 ARG A1065
VAL A1046
PHE A1118
GLU A1032
 None
 1.38A 1k2tA-4d8oA:
2.1
1k2tB-4d8oA:
undetectable		 1k2tA-4d8oA:
20.07
1k2tB-4d8oA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2T_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.33A 1k2tA-4d8oA:
2.1
1k2tB-4d8oA:
undetectable		 1k2tA-4d8oA:
20.07
1k2tB-4d8oA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM5_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 6 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.34A 1om5A-4d8oA:
undetectable
1om5B-4d8oA:
undetectable		 1om5A-4d8oA:
19.77
1om5B-4d8oA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6J_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 ARG A1065
VAL A1046
PHE A1118
GLU A1032
 None
 1.35A 1p6jA-4d8oA:
undetectable
1p6jB-4d8oA:
undetectable		 1p6jA-4d8oA:
19.77
1p6jB-4d8oA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6J_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.34A 1p6jA-4d8oA:
undetectable
1p6jB-4d8oA:
undetectable		 1p6jA-4d8oA:
19.77
1p6jB-4d8oA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 8 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.32A 1rs6A-4d8oA:
undetectable
1rs6B-4d8oA:
undetectable		 1rs6A-4d8oA:
19.77
1rs6B-4d8oA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 ARG A1065
VAL A1046
PHE A1118
GLU A1032
 None
 1.40A 1rs7A-4d8oA:
undetectable
1rs7B-4d8oA:
undetectable		 1rs7A-4d8oA:
19.77
1rs7B-4d8oA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.35A 1rs7A-4d8oA:
undetectable
1rs7B-4d8oA:
undetectable		 1rs7A-4d8oA:
19.77
1rs7B-4d8oA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ULV_A_ACRA3000_1
(GLUCODEXTRANASE)		 4d8o ANKYRIN-2
(Homo
sapiens) 		5 / 12 ALA A1510
TRP A1502
ARG A1505
ASP A1506
ARG A1312
 None
 1.31A 1ulvA-4d8oA:
3.0		 1ulvA-4d8oA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX3_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 6 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.35A 2hx3A-4d8oA:
undetectable
2hx3B-4d8oA:
undetectable		 2hx3A-4d8oA:
19.44
2hx3B-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX4_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.35A 2hx4A-4d8oA:
undetectable
2hx4B-4d8oA:
undetectable		 2hx4A-4d8oA:
19.44
2hx4B-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3N_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.35A 3b3nA-4d8oA:
undetectable
3b3nB-4d8oA:
undetectable		 3b3nA-4d8oA:
19.44
3b3nB-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3O_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.34A 3b3oA-4d8oA:
undetectable
3b3oB-4d8oA:
undetectable		 3b3oA-4d8oA:
19.44
3b3oB-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3P_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 ARG A1065
VAL A1046
PHE A1118
GLU A1032
 None
 1.34A 3b3pA-4d8oA:
undetectable
3b3pB-4d8oA:
undetectable		 3b3pA-4d8oA:
19.44
3b3pB-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3P_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 8 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.31A 3b3pA-4d8oA:
undetectable
3b3pB-4d8oA:
undetectable		 3b3pA-4d8oA:
19.44
3b3pB-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.37A 3jt3A-4d8oA:
undetectable
3jt3B-4d8oA:
undetectable		 3jt3A-4d8oA:
19.44
3jt3B-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT8_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.37A 3jt8A-4d8oA:
undetectable
3jt8B-4d8oA:
undetectable		 3jt8A-4d8oA:
19.44
3jt8B-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.34A 3jwuA-4d8oA:
undetectable
3jwuB-4d8oA:
undetectable		 3jwuA-4d8oA:
19.50
3jwuB-4d8oA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.36A 3jwvA-4d8oA:
undetectable
3jwvB-4d8oA:
undetectable		 3jwvA-4d8oA:
19.50
3jwvB-4d8oA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L2V_A_RLTA397_1
(INTEGRASE)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 ASP A1113
PRO A1115
GLN A1116
GLU A1067
 None
 1.00A 3l2vA-4d8oA:
undetectable		 3l2vA-4d8oA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N2R_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.36A 3n2rA-4d8oA:
undetectable
3n2rB-4d8oA:
undetectable		 3n2rA-4d8oA:
19.44
3n2rB-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5V_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.40A 3n5vA-4d8oA:
undetectable
3n5vB-4d8oA:
undetectable		 3n5vA-4d8oA:
19.44
3n5vB-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLK_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.34A 3nlkA-4d8oA:
undetectable
3nlkB-4d8oA:
undetectable		 3nlkA-4d8oA:
19.50
3nlkB-4d8oA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 ARG A1065
VAL A1046
PHE A1118
GLU A1032
 None
 1.38A 3nlnA-4d8oA:
undetectable
3nlnB-4d8oA:
undetectable		 3nlnA-4d8oA:
19.50
3nlnB-4d8oA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.35A 3nlnA-4d8oA:
undetectable
3nlnB-4d8oA:
undetectable		 3nlnA-4d8oA:
19.50
3nlnB-4d8oA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 ARG A1065
VAL A1046
PHE A1118
GLU A1032
 None
 1.41A 3nloA-4d8oA:
undetectable
3nloB-4d8oA:
undetectable		 3nloA-4d8oA:
19.50
3nloB-4d8oA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.45A 3nloA-4d8oA:
undetectable
3nloB-4d8oA:
undetectable		 3nloA-4d8oA:
19.50
3nloB-4d8oA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.37A 3nlvA-4d8oA:
undetectable
3nlvB-4d8oA:
undetectable		 3nlvA-4d8oA:
19.44
3nlvB-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLW_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.37A 3nlwA-4d8oA:
undetectable
3nlwB-4d8oA:
undetectable		 3nlwA-4d8oA:
19.44
3nlwB-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLY_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 8 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.36A 3nlyA-4d8oA:
undetectable
3nlyB-4d8oA:
undetectable		 3nlyA-4d8oA:
19.44
3nlyB-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNY_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.37A 3nnyA-4d8oA:
undetectable
3nnyB-4d8oA:
undetectable		 3nnyA-4d8oA:
19.44
3nnyB-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNZ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.37A 3nnzA-4d8oA:
undetectable
3nnzB-4d8oA:
undetectable		 3nnzA-4d8oA:
19.44
3nnzB-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNE_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.38A 3pneA-4d8oA:
undetectable
3pneB-4d8oA:
undetectable		 3pneA-4d8oA:
19.44
3pneB-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SVP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 6 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.40A 3svpA-4d8oA:
undetectable
3svpB-4d8oA:
undetectable		 3svpA-4d8oA:
19.44
3svpB-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYL_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 ARG A1065
VAL A1046
PHE A1118
GLU A1032
 None
 1.39A 3tylA-4d8oA:
undetectable
3tylB-4d8oA:
undetectable		 3tylA-4d8oA:
19.44
3tylB-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.39A 3tynA-4d8oA:
undetectable
3tynB-4d8oA:
undetectable		 3tynA-4d8oA:
19.44
3tynB-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.36A 3tyoA-4d8oA:
undetectable
3tyoB-4d8oA:
undetectable		 3tyoA-4d8oA:
19.44
3tyoB-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.39A 3ufoA-4d8oA:
undetectable
3ufoB-4d8oA:
undetectable		 3ufoA-4d8oA:
19.44
3ufoB-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 ARG A1065
VAL A1046
PHE A1118
GLU A1032
 None
 1.33A 3ufpA-4d8oA:
undetectable
3ufpB-4d8oA:
undetectable		 3ufpA-4d8oA:
19.44
3ufpB-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.33A 3ufpA-4d8oA:
undetectable
3ufpB-4d8oA:
undetectable		 3ufpA-4d8oA:
19.44
3ufpB-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 6 ARG A1065
VAL A1046
PHE A1118
GLU A1032
 None
 1.37A 3ufqA-4d8oA:
undetectable
3ufqB-4d8oA:
undetectable		 3ufqA-4d8oA:
19.44
3ufqB-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.36A 3ufqA-4d8oA:
undetectable
3ufqB-4d8oA:
undetectable		 3ufqA-4d8oA:
19.44
3ufqB-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 6 ARG A1065
VAL A1046
PHE A1118
GLU A1032
 None
 1.26A 3ufrA-4d8oA:
undetectable
3ufrB-4d8oA:
undetectable		 3ufrA-4d8oA:
19.44
3ufrB-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.36A 3ufrA-4d8oA:
undetectable
3ufrB-4d8oA:
undetectable		 3ufrA-4d8oA:
19.44
3ufrB-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFS_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.35A 3ufsA-4d8oA:
undetectable
3ufsB-4d8oA:
undetectable		 3ufsA-4d8oA:
19.44
3ufsB-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.36A 3uftA-4d8oA:
undetectable
3uftB-4d8oA:
undetectable		 3uftA-4d8oA:
19.44
3uftB-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 ARG A1065
VAL A1046
PHE A1118
GLU A1032
 None
 1.38A 3ufuA-4d8oA:
undetectable
3ufuB-4d8oA:
undetectable		 3ufuA-4d8oA:
19.44
3ufuB-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFW_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 6 ARG A1065
VAL A1046
PHE A1118
GLU A1032
 None
 1.37A 3ufwA-4d8oA:
undetectable
3ufwB-4d8oA:
undetectable		 3ufwA-4d8oA:
19.44
3ufwB-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFW_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 6 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.36A 3ufwA-4d8oA:
undetectable
3ufwB-4d8oA:
undetectable		 3ufwA-4d8oA:
19.44
3ufwB-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_D_VIVD301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		5 / 12 LEU A1026
ILE A1109
ILE A1031
LEU A1008
VAL A1321
 None
 0.91A 3w68D-4d8oA:
2.6		 3w68D-4d8oA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C39_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.35A 4c39A-4d8oA:
undetectable
4c39B-4d8oA:
undetectable		 4c39A-4d8oA:
19.44
4c39B-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.35A 4canA-4d8oA:
undetectable
4canB-4d8oA:
undetectable		 4canA-4d8oA:
19.44
4canB-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 ARG A1065
VAL A1046
PHE A1118
GLU A1032
 None
 1.37A 4caoA-4d8oA:
undetectable
4caoB-4d8oA:
undetectable		 4caoA-4d8oA:
19.44
4caoB-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.37A 4caoA-4d8oA:
undetectable
4caoB-4d8oA:
undetectable		 4caoA-4d8oA:
19.44
4caoB-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.37A 4caqA-4d8oA:
undetectable
4caqB-4d8oA:
undetectable		 4caqA-4d8oA:
19.44
4caqB-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CDT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 ARG A1065
VAL A1046
PHE A1118
GLU A1032
 None
 1.38A 4cdtA-4d8oA:
undetectable
4cdtB-4d8oA:
undetectable		 4cdtA-4d8oA:
19.44
4cdtB-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CDT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.38A 4cdtA-4d8oA:
undetectable
4cdtB-4d8oA:
undetectable		 4cdtA-4d8oA:
19.44
4cdtB-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.37A 4ctpA-4d8oA:
undetectable
4ctpB-4d8oA:
undetectable		 4ctpA-4d8oA:
19.44
4ctpB-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.37A 4ctqA-4d8oA:
undetectable
4ctqB-4d8oA:
undetectable		 4ctqA-4d8oA:
19.44
4ctqB-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.39A 4ctrA-4d8oA:
undetectable
4ctrB-4d8oA:
undetectable		 4ctrA-4d8oA:
19.44
4ctrB-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.36A 4cttA-4d8oA:
undetectable
4cttB-4d8oA:
undetectable		 4cttA-4d8oA:
19.44
4cttB-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Z_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.38A 4d2zA-4d8oA:
undetectable
4d2zB-4d8oA:
undetectable		 4d2zA-4d8oA:
19.44
4d2zB-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D30_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.37A 4d30A-4d8oA:
undetectable
4d30B-4d8oA:
undetectable		 4d30A-4d8oA:
19.44
4d30B-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D31_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 ARG A1065
VAL A1046
PHE A1118
GLU A1032
 None
 1.36A 4d31A-4d8oA:
undetectable
4d31B-4d8oA:
undetectable		 4d31A-4d8oA:
19.44
4d31B-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGK_A_0TXA302_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 GLY A1135
GLY A1136
ASN A1129
GLU A1152
 None
 0.93A 4fgkB-4d8oA:
undetectable		 4fgkB-4d8oA:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_D_CLQD303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 6 GLY A1135
GLY A1136
ASN A1129
GLU A1152
 None
 0.97A 4fglD-4d8oA:
undetectable		 4fglD-4d8oA:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GQE_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.36A 4gqeA-4d8oA:
undetectable
4gqeB-4d8oA:
undetectable		 4gqeA-4d8oA:
19.44
4gqeB-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSH_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 6 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.41A 4jshA-4d8oA:
undetectable
4jshB-4d8oA:
undetectable		 4jshA-4d8oA:
19.44
4jshB-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5D_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.35A 4k5dA-4d8oA:
undetectable
4k5dB-4d8oA:
undetectable		 4k5dA-4d8oA:
19.44
4k5dB-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5F_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.37A 4k5fA-4d8oA:
undetectable
4k5fB-4d8oA:
undetectable		 4k5fA-4d8oA:
19.44
4k5fB-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCI_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.40A 4kciA-4d8oA:
undetectable
4kciB-4d8oA:
undetectable		 4kciA-4d8oA:
19.44
4kciB-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCL_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 6 ARG A1065
VAL A1046
PHE A1118
GLU A1032
 None
 1.39A 4kclA-4d8oA:
undetectable
4kclB-4d8oA:
undetectable		 4kclA-4d8oA:
19.44
4kclB-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UGZ_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.38A 4ugzA-4d8oA:
undetectable
4ugzB-4d8oA:
undetectable		 4ugzA-4d8oA:
19.44
4ugzB-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 ARG A1065
VAL A1046
PHE A1118
GLU A1032
 None
 1.37A 4uh0A-4d8oA:
undetectable
4uh0B-4d8oA:
undetectable		 4uh0A-4d8oA:
19.44
4uh0B-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.36A 4uh0A-4d8oA:
undetectable
4uh0B-4d8oA:
undetectable		 4uh0A-4d8oA:
19.44
4uh0B-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH2_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.34A 4uh2A-4d8oA:
undetectable
4uh2B-4d8oA:
undetectable		 4uh2A-4d8oA:
19.44
4uh2B-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.40A 4uh4A-4d8oA:
undetectable
4uh4B-4d8oA:
undetectable		 4uh4A-4d8oA:
19.44
4uh4B-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPM_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.36A 4upmA-4d8oA:
undetectable
4upmB-4d8oA:
undetectable		 4upmA-4d8oA:
19.44
4upmB-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPN_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 ARG A1065
VAL A1046
PHE A1118
GLU A1032
 None
 1.36A 4upnA-4d8oA:
undetectable
4upnB-4d8oA:
undetectable		 4upnA-4d8oA:
19.44
4upnB-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPN_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.36A 4upnA-4d8oA:
undetectable
4upnB-4d8oA:
undetectable		 4upnA-4d8oA:
19.44
4upnB-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3V_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.35A 4v3vA-4d8oA:
undetectable
4v3vB-4d8oA:
undetectable		 4v3vA-4d8oA:
19.44
4v3vB-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.44A 5ad4A-4d8oA:
undetectable
5ad4B-4d8oA:
undetectable		 5ad4A-4d8oA:
19.44
5ad4B-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 ARG A1065
VAL A1046
PHE A1118
GLU A1032
 None
 1.39A 5ad5A-4d8oA:
undetectable
5ad5B-4d8oA:
undetectable		 5ad5A-4d8oA:
19.44
5ad5B-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 6 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.36A 5ad5A-4d8oA:
undetectable
5ad5B-4d8oA:
undetectable		 5ad5A-4d8oA:
19.44
5ad5B-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 ARG A1065
VAL A1046
PHE A1118
GLU A1032
 None
 1.40A 5ad6A-4d8oA:
undetectable
5ad6B-4d8oA:
undetectable		 5ad6A-4d8oA:
19.44
5ad6B-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD6_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.39A 5ad6A-4d8oA:
undetectable
5ad6B-4d8oA:
undetectable		 5ad6A-4d8oA:
19.44
5ad6B-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD7_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 6 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.37A 5ad7A-4d8oA:
undetectable
5ad7B-4d8oA:
undetectable		 5ad7A-4d8oA:
19.44
5ad7B-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD8_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 6 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.35A 5ad8A-4d8oA:
undetectable
5ad8B-4d8oA:
undetectable		 5ad8A-4d8oA:
19.44
5ad8B-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD9_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 ARG A1065
VAL A1046
PHE A1118
GLU A1032
 None
 1.35A 5ad9A-4d8oA:
undetectable
5ad9B-4d8oA:
undetectable		 5ad9A-4d8oA:
19.44
5ad9B-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD9_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 6 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.39A 5ad9A-4d8oA:
undetectable
5ad9B-4d8oA:
undetectable		 5ad9A-4d8oA:
19.44
5ad9B-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADA_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 ARG A1065
VAL A1046
PHE A1118
GLU A1032
 None
 1.35A 5adaA-4d8oA:
undetectable
5adaB-4d8oA:
undetectable		 5adaA-4d8oA:
19.44
5adaB-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADA_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.34A 5adaA-4d8oA:
undetectable
5adaB-4d8oA:
undetectable		 5adaA-4d8oA:
19.44
5adaB-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADB_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 6 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.39A 5adbA-4d8oA:
undetectable
5adbB-4d8oA:
undetectable		 5adbA-4d8oA:
19.44
5adbB-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADF_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 ARG A1065
VAL A1046
PHE A1118
GLU A1032
 None
 1.34A 5adfA-4d8oA:
undetectable
5adfB-4d8oA:
2.1		 5adfA-4d8oA:
20.13
5adfB-4d8oA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADG_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 ARG A1065
VAL A1046
PHE A1118
GLU A1032
 None
 1.34A 5adgA-4d8oA:
undetectable
5adgB-4d8oA:
undetectable		 5adgA-4d8oA:
20.13
5adgB-4d8oA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADI_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 ARG A1065
VAL A1046
PHE A1118
GLU A1032
 None
 1.38A 5adiA-4d8oA:
undetectable
5adiB-4d8oA:
2.0		 5adiA-4d8oA:
20.13
5adiB-4d8oA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGK_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.32A 5agkA-4d8oA:
undetectable
5agkB-4d8oA:
undetectable		 5agkA-4d8oA:
19.44
5agkB-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGL_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.35A 5aglA-4d8oA:
undetectable
5aglB-4d8oA:
undetectable		 5aglA-4d8oA:
19.44
5aglB-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.32A 5agoA-4d8oA:
undetectable
5agoB-4d8oA:
undetectable		 5agoA-4d8oA:
19.44
5agoB-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 6 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.41A 5fvpA-4d8oA:
2.1
5fvpB-4d8oA:
undetectable		 5fvpA-4d8oA:
19.44
5fvpB-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.41A 5fvuA-4d8oA:
undetectable
5fvuB-4d8oA:
undetectable		 5fvuA-4d8oA:
20.13
5fvuB-4d8oA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FW0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.36A 5fw0A-4d8oA:
undetectable
5fw0B-4d8oA:
undetectable		 5fw0A-4d8oA:
19.44
5fw0B-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0O_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.34A 5g0oA-4d8oA:
undetectable
5g0oB-4d8oA:
undetectable		 5g0oA-4d8oA:
19.44
5g0oB-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HRQ_I_IPHI101_0
(INSULIN A-CHAIN
INSULIN B-CHAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 6 VAL A1350
HIS A1366
CYH A1352
LEU A1311
 None
 1.10A 5hrqB-4d8oA:
undetectable
5hrqI-4d8oA:
undetectable
5hrqJ-4d8oA:
undetectable		 5hrqB-4d8oA:
4.59
5hrqI-4d8oA:
3.99
5hrqJ-4d8oA:
4.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HRQ_K_IPHK101_0
(INSULIN A-CHAIN
INSULIN B-CHAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 6 VAL A1350
HIS A1366
CYH A1352
LEU A1311
 None
 1.12A 5hrqH-4d8oA:
undetectable
5hrqK-4d8oA:
undetectable
5hrqL-4d8oA:
undetectable		 5hrqH-4d8oA:
4.59
5hrqK-4d8oA:
3.99
5hrqL-4d8oA:
4.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1O_H_DVAH9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 4d8o ANKYRIN-2
(Homo
sapiens) 		3 / 3 ALA A1510
ASN A1514
LEU A1515
 None
 0.41A 5i1oA-4d8oA:
undetectable		 5i1oA-4d8oA:
6.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKQ_A_JMSA602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4d8o ANKYRIN-2
(Homo
sapiens) 		3 / 3 VAL A1321
SER A1028
MET A1294
 None
 0.86A 5ikqA-4d8oA:
undetectable		 5ikqA-4d8oA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JLC_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 5 GLY A1234
THR A1235
GLY A1135
LEU A1189
 None
 0.90A 5jlcA-4d8oA:
undetectable		 5jlcA-4d8oA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNR_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.34A 5unrA-4d8oA:
undetectable
5unrB-4d8oA:
undetectable		 5unrA-4d8oA:
19.44
5unrB-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNS_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.35A 5unsA-4d8oA:
undetectable
5unsB-4d8oA:
undetectable		 5unsA-4d8oA:
19.44
5unsB-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNU_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 ARG A1065
VAL A1046
PHE A1118
GLU A1032
 None
 1.39A 5unuA-4d8oA:
undetectable
5unuB-4d8oA:
undetectable		 5unuA-4d8oA:
19.44
5unuB-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNU_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.38A 5unuA-4d8oA:
undetectable
5unuB-4d8oA:
undetectable		 5unuA-4d8oA:
19.44
5unuB-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNV_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 6 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.42A 5unvA-4d8oA:
undetectable
5unvB-4d8oA:
undetectable		 5unvA-4d8oA:
19.44
5unvB-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 ARG A1065
VAL A1046
PHE A1118
GLU A1032
 None
 1.36A 5unwA-4d8oA:
undetectable
5unwB-4d8oA:
undetectable		 5unwA-4d8oA:
19.44
5unwB-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.34A 5unwA-4d8oA:
undetectable
5unwB-4d8oA:
undetectable		 5unwA-4d8oA:
19.44
5unwB-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 ARG A1065
VAL A1046
PHE A1118
GLU A1032
 None
 1.44A 5unxA-4d8oA:
undetectable
5unxB-4d8oA:
undetectable		 5unxA-4d8oA:
19.44
5unxB-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 6 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.41A 5unxA-4d8oA:
undetectable
5unxB-4d8oA:
undetectable		 5unxA-4d8oA:
19.44
5unxB-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 ARG A1065
VAL A1046
PHE A1118
GLU A1032
 None
 1.38A 5unyA-4d8oA:
undetectable
5unyB-4d8oA:
undetectable		 5unyA-4d8oA:
19.44
5unyB-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.35A 5unyA-4d8oA:
undetectable
5unyB-4d8oA:
undetectable		 5unyA-4d8oA:
19.44
5unyB-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNZ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.35A 5unzA-4d8oA:
undetectable
5unzB-4d8oA:
undetectable		 5unzA-4d8oA:
19.44
5unzB-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO0_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.37A 5uo0A-4d8oA:
undetectable
5uo0B-4d8oA:
undetectable		 5uo0A-4d8oA:
19.44
5uo0B-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO1_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 ARG A1065
VAL A1046
PHE A1118
GLU A1032
 None
 1.33A 5uo1A-4d8oA:
undetectable
5uo1B-4d8oA:
undetectable		 5uo1A-4d8oA:
20.13
5uo1B-4d8oA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO1_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.37A 5uo1A-4d8oA:
undetectable
5uo1B-4d8oA:
undetectable		 5uo1A-4d8oA:
20.13
5uo1B-4d8oA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO3_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 ARG A1065
VAL A1046
PHE A1118
GLU A1032
 None
 1.37A 5uo3A-4d8oA:
undetectable
5uo3B-4d8oA:
undetectable		 5uo3A-4d8oA:
20.13
5uo3B-4d8oA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO3_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.41A 5uo3A-4d8oA:
undetectable
5uo3B-4d8oA:
undetectable		 5uo3A-4d8oA:
20.13
5uo3B-4d8oA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO4_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 ARG A1065
VAL A1046
PHE A1118
GLU A1032
 None
 1.37A 5uo4A-4d8oA:
undetectable
5uo4B-4d8oA:
undetectable		 5uo4A-4d8oA:
20.13
5uo4B-4d8oA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO4_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.38A 5uo4A-4d8oA:
undetectable
5uo4B-4d8oA:
undetectable		 5uo4A-4d8oA:
20.13
5uo4B-4d8oA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO5_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 ARG A1065
VAL A1046
PHE A1118
GLU A1032
 None
 1.36A 5uo5A-4d8oA:
undetectable
5uo5B-4d8oA:
undetectable		 5uo5A-4d8oA:
20.13
5uo5B-4d8oA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO5_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.40A 5uo5A-4d8oA:
undetectable
5uo5B-4d8oA:
undetectable		 5uo5A-4d8oA:
20.13
5uo5B-4d8oA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO6_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.36A 5uo6A-4d8oA:
undetectable
5uo6B-4d8oA:
undetectable		 5uo6A-4d8oA:
20.13
5uo6B-4d8oA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO7_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.38A 5uo7A-4d8oA:
undetectable
5uo7B-4d8oA:
undetectable		 5uo7A-4d8oA:
20.13
5uo7B-4d8oA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUI_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.35A 5vuiA-4d8oA:
2.0
5vuiB-4d8oA:
undetectable		 5vuiA-4d8oA:
19.44
5vuiB-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUK_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 ARG A1065
VAL A1046
PHE A1118
GLU A1032
 None
 1.36A 5vukA-4d8oA:
undetectable
5vukB-4d8oA:
undetectable		 5vukA-4d8oA:
19.44
5vukB-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUK_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.36A 5vukA-4d8oA:
undetectable
5vukB-4d8oA:
undetectable		 5vukA-4d8oA:
19.44
5vukB-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.36A 5vuoA-4d8oA:
2.1
5vuoB-4d8oA:
undetectable		 5vuoA-4d8oA:
19.44
5vuoB-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUQ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.32A 5vuqA-4d8oA:
undetectable
5vuqB-4d8oA:
undetectable		 5vuqA-4d8oA:
19.44
5vuqB-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUR_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.34A 5vurA-4d8oA:
undetectable
5vurB-4d8oA:
undetectable		 5vurA-4d8oA:
19.44
5vurB-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUS_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.30A 5vusA-4d8oA:
undetectable
5vusB-4d8oA:
undetectable		 5vusA-4d8oA:
19.44
5vusB-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUT_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.36A 5vutA-4d8oA:
undetectable
5vutB-4d8oA:
undetectable		 5vutA-4d8oA:
19.44
5vutB-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUU_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 ARG A1065
VAL A1046
PHE A1118
GLU A1032
 None
 1.39A 5vuuA-4d8oA:
undetectable
5vuuB-4d8oA:
undetectable		 5vuuA-4d8oA:
19.44
5vuuB-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUU_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.33A 5vuuA-4d8oA:
undetectable
5vuuB-4d8oA:
undetectable		 5vuuA-4d8oA:
19.44
5vuuB-4d8oA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 ARG A1065
VAL A1046
PHE A1118
GLU A1032
 None
 1.31A 5vuyA-4d8oA:
2.1
5vuyB-4d8oA:
undetectable		 5vuyA-4d8oA:
20.13
5vuyB-4d8oA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.33A 5vuyA-4d8oA:
2.1
5vuyB-4d8oA:
undetectable		 5vuyA-4d8oA:
20.13
5vuyB-4d8oA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV0_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 6 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.36A 5vv0A-4d8oA:
2.1
5vv0B-4d8oA:
2.1		 5vv0A-4d8oA:
20.10
5vv0B-4d8oA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV1_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 6 ARG A1065
VAL A1046
PHE A1118
GLU A1032
 None
 1.31A 5vv1A-4d8oA:
undetectable
5vv1B-4d8oA:
2.1		 5vv1A-4d8oA:
20.13
5vv1B-4d8oA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV2_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.39A 5vv2A-4d8oA:
undetectable
5vv2B-4d8oA:
2.1		 5vv2A-4d8oA:
20.13
5vv2B-4d8oA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV3_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 ARG A1065
VAL A1046
PHE A1118
GLU A1032
 None
 1.32A 5vv3A-4d8oA:
2.1
5vv3B-4d8oA:
undetectable		 5vv3A-4d8oA:
20.13
5vv3B-4d8oA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV3_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.36A 5vv3A-4d8oA:
2.1
5vv3B-4d8oA:
undetectable		 5vv3A-4d8oA:
20.13
5vv3B-4d8oA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV4_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.38A 5vv4A-4d8oA:
undetectable
5vv4B-4d8oA:
2.1		 5vv4A-4d8oA:
20.13
5vv4B-4d8oA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV5_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 ARG A1065
VAL A1046
PHE A1118
GLU A1032
 None
 1.37A 5vv5A-4d8oA:
undetectable
5vv5B-4d8oA:
undetectable		 5vv5A-4d8oA:
20.13
5vv5B-4d8oA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV5_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.39A 5vv5A-4d8oA:
undetectable
5vv5B-4d8oA:
undetectable		 5vv5A-4d8oA:
20.13
5vv5B-4d8oA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AK3_B_P2EB1201_1
(PROSTAGLANDIN E2
RECEPTOR EP3
SUBTYPE,SOLUBLE
CYTOCHROME B562)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 5 PRO A1420
VAL A1334
GLY A1354
VAL A1382
 None
 1.06A 6ak3B-4d8oA:
undetectable		 6ak3B-4d8oA:
9.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUQ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.39A 6auqA-4d8oA:
undetectable
6auqB-4d8oA:
undetectable		 6auqA-4d8oA:
8.30
6auqB-4d8oA:
8.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.35A 6auuA-4d8oA:
undetectable
6auuB-4d8oA:
undetectable		 6auuA-4d8oA:
8.30
6auuB-4d8oA:
8.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.37A 6auwA-4d8oA:
undetectable
6auwB-4d8oA:
undetectable		 6auwA-4d8oA:
8.30
6auwB-4d8oA:
8.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 ARG A1065
VAL A1046
PHE A1118
GLU A1032
 None
 1.37A 6auxA-4d8oA:
undetectable
6auxB-4d8oA:
undetectable		 6auxA-4d8oA:
8.30
6auxB-4d8oA:
8.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.35A 6auxA-4d8oA:
undetectable
6auxB-4d8oA:
undetectable		 6auxA-4d8oA:
8.30
6auxB-4d8oA:
8.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV1_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 PHE A1118
GLU A1032
ARG A1065
VAL A1046
 None
 1.43A 6av1A-4d8oA:
undetectable
6av1B-4d8oA:
undetectable		 6av1A-4d8oA:
10.23
6av1B-4d8oA:
10.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV2_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 ARG A1065
VAL A1046
PHE A1118
GLU A1032
 None
 1.38A 6av2A-4d8oA:
undetectable
6av2B-4d8oA:
undetectable		 6av2A-4d8oA:
10.23
6av2B-4d8oA:
10.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV5_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4d8o ANKYRIN-2
(Homo
sapiens) 		4 / 7 ARG A1065
VAL A1046
PHE A1118
GLU A1032
 None
 1.38A 6av5A-4d8oA:
undetectable
6av5B-4d8oA:
undetectable		 6av5A-4d8oA:
10.23
6av5B-4d8oA:
10.23