SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4d9i'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 9 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.08A 1c9sL-4d9iA:
undetectable
1c9sM-4d9iA:
undetectable		 1c9sL-4d9iA:
11.42
1c9sM-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_M_TRPM81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 9 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.10A 1c9sM-4d9iA:
undetectable
1c9sN-4d9iA:
undetectable		 1c9sM-4d9iA:
11.42
1c9sN-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.12A 1c9sN-4d9iA:
undetectable
1c9sO-4d9iA:
undetectable		 1c9sN-4d9iA:
11.42
1c9sO-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 11 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.12A 1c9sP-4d9iA:
undetectable
1c9sQ-4d9iA:
undetectable		 1c9sP-4d9iA:
11.42
1c9sQ-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 9 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.09A 1c9sS-4d9iA:
undetectable
1c9sT-4d9iA:
undetectable		 1c9sS-4d9iA:
11.42
1c9sT-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		4 / 7 GLY A 121
ALA A 128
THR A 117
THR A 119
 None
 0.89A 1c9sT-4d9iA:
undetectable
1c9sU-4d9iA:
undetectable		 1c9sT-4d9iA:
11.42
1c9sU-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.10A 1c9sL-4d9iA:
undetectable
1c9sV-4d9iA:
undetectable		 1c9sL-4d9iA:
11.42
1c9sV-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_B_ESTB600_1
(ESTROGEN RECEPTOR)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 9 ALA A 213
GLU A 212
ARG A  70
ILE A 334
LEU A  63
 None
 1.31A 1ereB-4d9iA:
undetectable		 1ereB-4d9iA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 9 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.08A 1gtfA-4d9iA:
undetectable
1gtfB-4d9iA:
undetectable		 1gtfA-4d9iA:
11.42
1gtfB-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 9 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.10A 1gtfO-4d9iA:
undetectable
1gtfP-4d9iA:
undetectable		 1gtfO-4d9iA:
11.42
1gtfP-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.11A 1gtfP-4d9iA:
undetectable
1gtfQ-4d9iA:
undetectable		 1gtfP-4d9iA:
11.42
1gtfQ-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 11 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.10A 1gtfQ-4d9iA:
undetectable
1gtfR-4d9iA:
undetectable		 1gtfQ-4d9iA:
11.42
1gtfR-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 11 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.11A 1gtfS-4d9iA:
undetectable
1gtfT-4d9iA:
undetectable		 1gtfS-4d9iA:
11.42
1gtfT-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.10A 1gtfT-4d9iA:
undetectable
1gtfU-4d9iA:
undetectable		 1gtfT-4d9iA:
11.42
1gtfU-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.12A 1gtfL-4d9iA:
undetectable
1gtfV-4d9iA:
undetectable		 1gtfL-4d9iA:
11.42
1gtfV-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 9 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.08A 1gtnG-4d9iA:
undetectable
1gtnH-4d9iA:
undetectable		 1gtnG-4d9iA:
11.42
1gtnH-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 9 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.15A 1gtnL-4d9iA:
undetectable
1gtnM-4d9iA:
undetectable		 1gtnL-4d9iA:
11.42
1gtnM-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 GLY A  81
HIS A 123
ALA A 131
THR A 117
ALA A 138
 LLP  A  77 ( 4.0A)
None
None
None
None
 1.33A 1gtnO-4d9iA:
undetectable
1gtnP-4d9iA:
undetectable		 1gtnO-4d9iA:
11.42
1gtnP-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ALA A 131
 None
 1.26A 1gtnO-4d9iA:
undetectable
1gtnP-4d9iA:
undetectable		 1gtnO-4d9iA:
11.42
1gtnP-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 9 GLY A 124
HIS A 123
ALA A 138
THR A 117
ALA A 131
 None
 1.22A 1gtnQ-4d9iA:
undetectable
1gtnR-4d9iA:
undetectable		 1gtnQ-4d9iA:
11.42
1gtnR-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_R_TRPR81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 9 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.10A 1gtnR-4d9iA:
undetectable
1gtnS-4d9iA:
undetectable		 1gtnR-4d9iA:
11.42
1gtnS-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 11 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.07A 1gtnT-4d9iA:
undetectable
1gtnU-4d9iA:
undetectable		 1gtnT-4d9iA:
11.42
1gtnU-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		6 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
ALA A 131
 None
 1.32A 1gtnU-4d9iA:
undetectable
1gtnV-4d9iA:
undetectable		 1gtnU-4d9iA:
11.42
1gtnV-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICT_D_T44D129_1
(TRANSTHYRETIN)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		4 / 6 LYS A  61
LEU A  63
LEU A 372
THR A 225
 None
 0.98A 1ictB-4d9iA:
undetectable		 1ictB-4d9iA:
16.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKU_A_ESTA600_1
(ESTRADIOL RECEPTOR)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 ALA A 213
GLU A 212
ARG A  70
ILE A 334
LEU A  63
 None
 1.22A 1qkuA-4d9iA:
undetectable		 1qkuA-4d9iA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKU_B_ESTB600_1
(ESTRADIOL RECEPTOR)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 ALA A 213
GLU A 212
ARG A  70
ILE A 334
LEU A  63
 None
 1.22A 1qkuB-4d9iA:
undetectable		 1qkuB-4d9iA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKU_C_ESTC600_1
(ESTRADIOL RECEPTOR)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 ALA A 213
GLU A 212
ARG A  70
ILE A 334
LEU A  63
 None
 1.22A 1qkuC-4d9iA:
undetectable		 1qkuC-4d9iA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_A_VIBA501_1
(YKOF)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		4 / 8 PHE A   4
SER A   5
LEU A   6
ILE A 310
 None
 0.85A 1sbrA-4d9iA:
undetectable		 1sbrA-4d9iA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_B_VIBB503_1
(YKOF)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		4 / 7 PHE A   4
SER A   5
ILE A  10
ILE A   8
 None
 1.00A 1sbrB-4d9iA:
undetectable		 1sbrB-4d9iA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SS4_A_ACTA411_0
(GLYOXALASE FAMILY
PROTEIN)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		4 / 5 TRP A 192
VAL A 172
THR A 175
ILE A 198
 None
 1.28A 1ss4A-4d9iA:
0.3		 1ss4A-4d9iA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TYR_A_9CRA131_1
(TRANSTHYRETIN)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		4 / 6 LYS A  61
LEU A  63
LEU A 372
THR A 225
 None
 1.03A 1tyrA-4d9iA:
undetectable		 1tyrA-4d9iA:
16.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_M_TRPM81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 11 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.11A 1utdM-4d9iA:
undetectable
1utdN-4d9iA:
undetectable		 1utdM-4d9iA:
11.42
1utdN-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_N_TRPN81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.10A 1utdN-4d9iA:
undetectable
1utdO-4d9iA:
undetectable		 1utdN-4d9iA:
11.42
1utdO-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_R_TRPR81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.12A 1utdR-4d9iA:
undetectable
1utdS-4d9iA:
undetectable		 1utdR-4d9iA:
11.42
1utdS-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_U_TRPU81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.12A 1utdU-4d9iA:
undetectable
1utdV-4d9iA:
undetectable		 1utdU-4d9iA:
11.42
1utdV-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WMQ_A_HISA2001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		4 / 6 ILE A 202
GLY A  81
ALA A  82
HIS A 123
 None
LLP  A  77 ( 4.0A)
None
None
 0.84A 1wmqA-4d9iA:
undetectable		 1wmqA-4d9iA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WMQ_B_HISB1001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		4 / 6 ILE A 202
GLY A  81
ALA A  82
HIS A 123
 None
LLP  A  77 ( 4.0A)
None
None
 0.83A 1wmqB-4d9iA:
undetectable		 1wmqB-4d9iA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WPU_A_HISA2001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		4 / 6 ILE A 202
GLY A  81
ALA A  82
HIS A 123
 None
LLP  A  77 ( 4.0A)
None
None
 0.84A 1wpuA-4d9iA:
undetectable		 1wpuA-4d9iA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WPU_B_HISB1001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		4 / 6 ILE A 202
GLY A  81
ALA A  82
HIS A 123
 None
LLP  A  77 ( 4.0A)
None
None
 0.83A 1wpuB-4d9iA:
undetectable		 1wpuB-4d9iA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRQ_A_HISA2001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		4 / 6 ILE A 202
GLY A  81
ALA A  82
HIS A 123
 None
LLP  A  77 ( 4.0A)
None
None
 0.84A 1wrqA-4d9iA:
undetectable		 1wrqA-4d9iA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRQ_B_HISB1001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		4 / 6 ILE A 202
GLY A  81
ALA A  82
HIS A 123
 None
LLP  A  77 ( 4.0A)
None
None
 0.82A 1wrqB-4d9iA:
undetectable		 1wrqB-4d9iA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1M_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		4 / 8 VAL A 323
GLY A 320
VAL A 373
ILE A  62
 None
 0.80A 2a1mB-4d9iA:
undetectable		 2a1mB-4d9iA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ROX_B_T44B128_1
(TRANSTHYRETIN)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		4 / 6 LYS A  61
LEU A  63
LEU A 372
THR A 225
 None
 1.00A 2roxB-4d9iA:
undetectable		 2roxB-4d9iA:
16.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DEU_A_SALA305_1
(TRANSCRIPTIONAL
REGULATOR SLYA)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		4 / 7 THR A 171
THR A 175
ILE A 162
THR A 118
 None
 0.86A 3deuA-4d9iA:
undetectable		 3deuA-4d9iA:
14.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H52_D_486D2_1
(GLUCOCORTICOID
RECEPTOR)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 12 GLY A 242
VAL A 240
MET A 203
LEU A  23
LEU A 297
 None
 1.43A 3h52D-4d9iA:
undetectable		 3h52D-4d9iA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MTE_B_SAMB220_0
(16S RRNA METHYLASE)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 12 GLY A 124
GLY A 121
VAL A 151
ALA A 159
ALA A 138
 None
 1.02A 3mteB-4d9iA:
undetectable		 3mteB-4d9iA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8Z_A_FLPA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 12 VAL A 323
VAL A  64
LEU A  50
GLY A 340
ALA A 341
 None
None
None
LLP  A  77 ( 4.7A)
None
 1.08A 3n8zA-4d9iA:
undetectable		 3n8zA-4d9iA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NT1_A_NPSA5_1
(PROSTAGLANDIN-ENDOPE
ROXIDE SYNTHASE 2)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 12 VAL A  64
LEU A  50
GLY A 340
ALA A 341
LEU A 344
 None
None
LLP  A  77 ( 4.7A)
None
None
 1.00A 3nt1A-4d9iA:
undetectable		 3nt1A-4d9iA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NT1_B_NPSB4_1
(PROSTAGLANDIN-ENDOPE
ROXIDE SYNTHASE 2)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 12 VAL A  64
LEU A  50
GLY A 340
ALA A 341
LEU A 344
 None
None
LLP  A  77 ( 4.7A)
None
None
 0.98A 3nt1B-4d9iA:
undetectable		 3nt1B-4d9iA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_C_SAMC6735_0
(16S RRNA METHYLASE)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 12 GLY A 124
GLY A 121
VAL A 151
ALA A 159
ALA A 138
 None
 1.06A 3p2kC-4d9iA:
2.2		 3p2kC-4d9iA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_D_SAMD6735_0
(16S RRNA METHYLASE)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 12 GLY A 124
GLY A 121
VAL A 151
ALA A 159
ALA A 138
 None
 1.05A 3p2kD-4d9iA:
undetectable		 3p2kD-4d9iA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RC0_A_SAMA484_0
(N-LYSINE
METHYLTRANSFERASE
SETD6)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 11 VAL A 342
ALA A 341
GLY A 320
TYR A 385
LEU A 289
 None
None
None
None
LLP  A  77 (-4.8A)
 1.25A 3rc0A-4d9iA:
undetectable		 3rc0A-4d9iA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SXJ_A_SAMA258_0
(PUTATIVE
METHYLTRANSFERASE)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 12 GLY A 234
GLY A 232
LEU A 229
ALA A 235
TYR A 206
 LLP  A  77 ( 3.3A)
LLP  A  77 (-3.4A)
None
LLP  A  77 ( 3.3A)
LLP  A  77 ( 4.9A)
 1.24A 3sxjA-4d9iA:
2.4		 3sxjA-4d9iA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SXJ_B_SAMB258_0
(PUTATIVE
METHYLTRANSFERASE)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 12 GLY A 234
GLY A 232
LEU A 229
ALA A 235
TYR A 206
 LLP  A  77 ( 3.3A)
LLP  A  77 (-3.4A)
None
LLP  A  77 ( 3.3A)
LLP  A  77 ( 4.9A)
 1.24A 3sxjB-4d9iA:
2.4		 3sxjB-4d9iA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7S_C_SAMC300_0
(PUTATIVE
METHYLTRANSFERASE)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 12 ARG A  70
GLY A 205
SER A  25
GLU A 212
ALA A 210
 None
 1.45A 3t7sC-4d9iA:
2.5		 3t7sC-4d9iA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_B_VIVB301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 12 TYR A 385
VAL A 389
LEU A 319
VAL A 373
LEU A  53
 None
 1.01A 3w68B-4d9iA:
undetectable		 3w68B-4d9iA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COX_C_IMNC701_1
(CYCLOOXYGENASE-2)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 12 VAL A 373
LEU A 228
VAL A 342
GLY A 320
ALA A 341
 None
 1.15A 4coxC-4d9iA:
undetectable		 4coxC-4d9iA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7B_A_TCWA1126_1
(TRANSTHYRETIN)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		4 / 6 LYS A  61
LEU A  63
LEU A 372
THR A 225
 None
 1.18A 4d7bB-4d9iA:
undetectable		 4d7bB-4d9iA:
15.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_A_ADNA401_2
(ADENOSINE KINASE)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		4 / 4 LEU A  79
ILE A  39
GLY A  80
PHE A  35
 None
None
LLP  A  77 ( 3.7A)
None
 1.07A 4dc3A-4d9iA:
3.1		 4dc3A-4d9iA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_A_ECNA403_1
(FLAVOHEMOGLOBIN)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 12 ALA A 348
LEU A 347
VAL A 258
LEU A 228
ILE A  10
 None
 1.09A 4g1bA-4d9iA:
2.4		 4g1bA-4d9iA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JX1_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 PHE A  57
LEU A 319
GLY A 320
VAL A 373
ILE A  62
 None
 1.19A 4jx1B-4d9iA:
undetectable		 4jx1B-4d9iA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PH9_A_IBPA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 VAL A  64
LEU A  50
GLY A 340
ALA A 341
LEU A 344
 None
None
LLP  A  77 ( 4.7A)
None
None
 1.02A 4ph9A-4d9iA:
0.4		 4ph9A-4d9iA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PH9_B_IBPB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 VAL A  64
LEU A  50
GLY A 340
ALA A 341
LEU A 344
 None
None
LLP  A  77 ( 4.7A)
None
None
 1.01A 4ph9B-4d9iA:
0.1		 4ph9B-4d9iA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRW_D_LURD705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		6 / 12 VAL A 373
LEU A 228
LEU A 319
VAL A 342
GLY A 320
ALA A 341
 None
 1.41A 4rrwD-4d9iA:
undetectable		 4rrwD-4d9iA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRZ_D_LURD705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		6 / 12 VAL A 373
LEU A 228
LEU A 319
VAL A 342
GLY A 320
ALA A 341
 None
 1.41A 4rrzD-4d9iA:
undetectable		 4rrzD-4d9iA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RS0_A_IBPA706_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 9 VAL A  64
LEU A  50
GLY A 340
ALA A 341
LEU A 344
 None
None
LLP  A  77 ( 4.7A)
None
None
 0.95A 4rs0A-4d9iA:
undetectable		 4rs0A-4d9iA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4S0V_A_SUVA2001_2
(HUMAN OREXIN
RECEPTOR TYPE 2
FUSION PROTEIN TO P.
ABYSII GLYCOGEN
SYNTHASE)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		4 / 5 ILE A 198
PRO A 199
TYR A 168
VAL A 172
 None
None
TRS  A 401 (-4.5A)
None
 0.96A 4s0vA-4d9iA:
undetectable		 4s0vA-4d9iA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XOY_A_DX4A401_0
(MITOGEN-ACTIVATED
PROTEIN KINASE 1)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		4 / 6 ALA A 130
GLN A 133
MET A  78
LEU A  73
 None
 1.08A 4xoyA-4d9iA:
undetectable		 4xoyA-4d9iA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BOJ_A_4TXA201_1
(TRANSTHYRETIN)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		4 / 6 LYS A  61
LEU A  63
LEU A 372
THR A 225
 None
 1.07A 5bojA-4d9iA:
undetectable		 5bojA-4d9iA:
16.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BOJ_B_4TXB201_1
(TRANSTHYRETIN)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		4 / 7 LYS A  61
LEU A  63
LEU A 372
THR A 225
 None
 1.04A 5bojB-4d9iA:
undetectable		 5bojB-4d9iA:
16.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 9 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.07A 5eeuC-4d9iA:
undetectable
5eeuD-4d9iA:
undetectable		 5eeuC-4d9iA:
11.42
5eeuD-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.08A 5eeuG-4d9iA:
undetectable
5eeuH-4d9iA:
undetectable		 5eeuG-4d9iA:
11.42
5eeuH-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		6 / 12 ALA A 131
GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.30A 5eeuI-4d9iA:
undetectable
5eeuJ-4d9iA:
undetectable		 5eeuI-4d9iA:
11.42
5eeuJ-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.13A 5eeuN-4d9iA:
undetectable
5eeuO-4d9iA:
undetectable		 5eeuN-4d9iA:
11.42
5eeuO-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.13A 5eeuO-4d9iA:
undetectable
5eeuP-4d9iA:
undetectable		 5eeuO-4d9iA:
11.42
5eeuP-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.11A 5eeuP-4d9iA:
undetectable
5eeuQ-4d9iA:
undetectable		 5eeuP-4d9iA:
11.42
5eeuQ-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.11A 5eeuR-4d9iA:
undetectable
5eeuS-4d9iA:
undetectable		 5eeuR-4d9iA:
11.42
5eeuS-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.09A 5eeuS-4d9iA:
undetectable
5eeuT-4d9iA:
undetectable		 5eeuS-4d9iA:
11.42
5eeuT-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.11A 5eeuT-4d9iA:
undetectable
5eeuU-4d9iA:
undetectable		 5eeuT-4d9iA:
11.42
5eeuU-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.10A 5eeuU-4d9iA:
undetectable
5eeuV-4d9iA:
undetectable		 5eeuU-4d9iA:
11.42
5eeuV-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 9 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.07A 5eevC-4d9iA:
undetectable
5eevD-4d9iA:
undetectable		 5eevC-4d9iA:
11.42
5eevD-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.08A 5eevG-4d9iA:
undetectable
5eevH-4d9iA:
undetectable		 5eevG-4d9iA:
11.42
5eevH-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		6 / 12 ALA A 131
GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.30A 5eevI-4d9iA:
undetectable
5eevJ-4d9iA:
undetectable		 5eevI-4d9iA:
11.42
5eevJ-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.14A 5eevN-4d9iA:
undetectable
5eevO-4d9iA:
undetectable		 5eevN-4d9iA:
11.42
5eevO-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.13A 5eevO-4d9iA:
undetectable
5eevP-4d9iA:
undetectable		 5eevO-4d9iA:
11.42
5eevP-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.11A 5eevP-4d9iA:
undetectable
5eevQ-4d9iA:
undetectable		 5eevP-4d9iA:
11.42
5eevQ-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.11A 5eevR-4d9iA:
undetectable
5eevS-4d9iA:
undetectable		 5eevR-4d9iA:
11.42
5eevS-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.09A 5eevS-4d9iA:
undetectable
5eevT-4d9iA:
undetectable		 5eevS-4d9iA:
11.42
5eevT-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.11A 5eevT-4d9iA:
undetectable
5eevU-4d9iA:
undetectable		 5eevT-4d9iA:
11.42
5eevU-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.10A 5eevU-4d9iA:
undetectable
5eevV-4d9iA:
undetectable		 5eevU-4d9iA:
11.42
5eevV-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 9 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.06A 5eewC-4d9iA:
undetectable
5eewD-4d9iA:
undetectable		 5eewC-4d9iA:
11.42
5eewD-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.08A 5eewG-4d9iA:
undetectable
5eewH-4d9iA:
undetectable		 5eewG-4d9iA:
11.42
5eewH-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		6 / 12 ALA A 131
GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.29A 5eewI-4d9iA:
undetectable
5eewJ-4d9iA:
undetectable		 5eewI-4d9iA:
11.42
5eewJ-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.13A 5eewN-4d9iA:
undetectable
5eewO-4d9iA:
undetectable		 5eewN-4d9iA:
11.42
5eewO-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.13A 5eewO-4d9iA:
undetectable
5eewP-4d9iA:
undetectable		 5eewO-4d9iA:
11.42
5eewP-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.11A 5eewP-4d9iA:
undetectable
5eewQ-4d9iA:
undetectable		 5eewP-4d9iA:
11.42
5eewQ-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.11A 5eewR-4d9iA:
undetectable
5eewS-4d9iA:
undetectable		 5eewR-4d9iA:
11.42
5eewS-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.09A 5eewS-4d9iA:
undetectable
5eewT-4d9iA:
undetectable		 5eewS-4d9iA:
11.42
5eewT-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.11A 5eewT-4d9iA:
undetectable
5eewU-4d9iA:
undetectable		 5eewT-4d9iA:
11.42
5eewU-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.10A 5eewU-4d9iA:
undetectable
5eewV-4d9iA:
undetectable		 5eewU-4d9iA:
11.42
5eewV-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 9 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.07A 5eexC-4d9iA:
undetectable
5eexD-4d9iA:
undetectable		 5eexC-4d9iA:
11.42
5eexD-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.09A 5eexG-4d9iA:
undetectable
5eexH-4d9iA:
undetectable		 5eexG-4d9iA:
11.42
5eexH-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 11 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.07A 5eexI-4d9iA:
undetectable
5eexJ-4d9iA:
undetectable		 5eexI-4d9iA:
11.42
5eexJ-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.05A 5eexA-4d9iA:
undetectable
5eexK-4d9iA:
undetectable		 5eexA-4d9iA:
11.42
5eexK-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.13A 5eexN-4d9iA:
undetectable
5eexO-4d9iA:
undetectable		 5eexN-4d9iA:
11.42
5eexO-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.13A 5eexO-4d9iA:
undetectable
5eexP-4d9iA:
undetectable		 5eexO-4d9iA:
11.42
5eexP-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.11A 5eexP-4d9iA:
undetectable
5eexQ-4d9iA:
undetectable		 5eexP-4d9iA:
11.42
5eexQ-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.11A 5eexR-4d9iA:
undetectable
5eexS-4d9iA:
undetectable		 5eexR-4d9iA:
11.42
5eexS-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.09A 5eexS-4d9iA:
undetectable
5eexT-4d9iA:
undetectable		 5eexS-4d9iA:
11.42
5eexT-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.11A 5eexT-4d9iA:
undetectable
5eexU-4d9iA:
undetectable		 5eexT-4d9iA:
11.42
5eexU-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.10A 5eexU-4d9iA:
undetectable
5eexV-4d9iA:
undetectable		 5eexU-4d9iA:
11.42
5eexV-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 9 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.06A 5eeyC-4d9iA:
undetectable
5eeyD-4d9iA:
undetectable		 5eeyC-4d9iA:
11.42
5eeyD-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.08A 5eeyG-4d9iA:
undetectable
5eeyH-4d9iA:
undetectable		 5eeyG-4d9iA:
11.42
5eeyH-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 11 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.07A 5eeyI-4d9iA:
undetectable
5eeyJ-4d9iA:
undetectable		 5eeyI-4d9iA:
11.42
5eeyJ-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.14A 5eeyN-4d9iA:
undetectable
5eeyO-4d9iA:
undetectable		 5eeyN-4d9iA:
11.42
5eeyO-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.13A 5eeyO-4d9iA:
undetectable
5eeyP-4d9iA:
undetectable		 5eeyO-4d9iA:
11.42
5eeyP-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.11A 5eeyP-4d9iA:
undetectable
5eeyQ-4d9iA:
undetectable		 5eeyP-4d9iA:
11.42
5eeyQ-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.11A 5eeyR-4d9iA:
undetectable
5eeyS-4d9iA:
undetectable		 5eeyR-4d9iA:
11.42
5eeyS-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.09A 5eeyS-4d9iA:
undetectable
5eeyT-4d9iA:
undetectable		 5eeyS-4d9iA:
11.42
5eeyT-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.11A 5eeyT-4d9iA:
undetectable
5eeyU-4d9iA:
undetectable		 5eeyT-4d9iA:
11.42
5eeyU-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.10A 5eeyU-4d9iA:
undetectable
5eeyV-4d9iA:
undetectable		 5eeyU-4d9iA:
11.42
5eeyV-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 9 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.06A 5eezC-4d9iA:
undetectable
5eezD-4d9iA:
undetectable		 5eezC-4d9iA:
11.42
5eezD-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.08A 5eezG-4d9iA:
undetectable
5eezH-4d9iA:
undetectable		 5eezG-4d9iA:
11.42
5eezH-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 11 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.07A 5eezI-4d9iA:
undetectable
5eezJ-4d9iA:
undetectable		 5eezI-4d9iA:
11.42
5eezJ-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		4 / 8 GLY A 121
ALA A 128
THR A 117
THR A 119
 None
 0.89A 5eezL-4d9iA:
undetectable
5eezV-4d9iA:
undetectable		 5eezL-4d9iA:
11.42
5eezV-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.14A 5eezN-4d9iA:
undetectable
5eezO-4d9iA:
undetectable		 5eezN-4d9iA:
11.42
5eezO-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.12A 5eezO-4d9iA:
undetectable
5eezP-4d9iA:
undetectable		 5eezO-4d9iA:
11.42
5eezP-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.11A 5eezP-4d9iA:
undetectable
5eezQ-4d9iA:
undetectable		 5eezP-4d9iA:
11.42
5eezQ-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.11A 5eezR-4d9iA:
undetectable
5eezS-4d9iA:
undetectable		 5eezR-4d9iA:
11.42
5eezS-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.09A 5eezS-4d9iA:
undetectable
5eezT-4d9iA:
undetectable		 5eezS-4d9iA:
11.42
5eezT-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.11A 5eezT-4d9iA:
undetectable
5eezU-4d9iA:
undetectable		 5eezT-4d9iA:
11.42
5eezU-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.10A 5eezU-4d9iA:
undetectable
5eezV-4d9iA:
undetectable		 5eezU-4d9iA:
11.42
5eezV-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 9 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.07A 5ef0C-4d9iA:
undetectable
5ef0D-4d9iA:
undetectable		 5ef0C-4d9iA:
11.42
5ef0D-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.08A 5ef0G-4d9iA:
undetectable
5ef0H-4d9iA:
undetectable		 5ef0G-4d9iA:
11.42
5ef0H-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 11 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.07A 5ef0I-4d9iA:
undetectable
5ef0J-4d9iA:
undetectable		 5ef0I-4d9iA:
11.42
5ef0J-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.05A 5ef0A-4d9iA:
undetectable
5ef0K-4d9iA:
undetectable		 5ef0A-4d9iA:
11.42
5ef0K-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.14A 5ef0N-4d9iA:
undetectable
5ef0O-4d9iA:
undetectable		 5ef0N-4d9iA:
11.42
5ef0O-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.12A 5ef0O-4d9iA:
undetectable
5ef0P-4d9iA:
undetectable		 5ef0O-4d9iA:
11.42
5ef0P-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.11A 5ef0P-4d9iA:
undetectable
5ef0Q-4d9iA:
undetectable		 5ef0P-4d9iA:
11.42
5ef0Q-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.11A 5ef0R-4d9iA:
undetectable
5ef0S-4d9iA:
undetectable		 5ef0R-4d9iA:
11.42
5ef0S-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.09A 5ef0S-4d9iA:
undetectable
5ef0T-4d9iA:
undetectable		 5ef0S-4d9iA:
11.42
5ef0T-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.11A 5ef0T-4d9iA:
undetectable
5ef0U-4d9iA:
undetectable		 5ef0T-4d9iA:
11.42
5ef0U-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.10A 5ef0U-4d9iA:
undetectable
5ef0V-4d9iA:
undetectable		 5ef0U-4d9iA:
11.42
5ef0V-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 9 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.07A 5ef1C-4d9iA:
undetectable
5ef1D-4d9iA:
undetectable		 5ef1C-4d9iA:
11.42
5ef1D-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.08A 5ef1G-4d9iA:
undetectable
5ef1H-4d9iA:
undetectable		 5ef1G-4d9iA:
11.42
5ef1H-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 11 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.07A 5ef1I-4d9iA:
undetectable
5ef1J-4d9iA:
undetectable		 5ef1I-4d9iA:
11.42
5ef1J-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		4 / 8 GLY A 121
ALA A 128
THR A 117
THR A 119
 None
 0.89A 5ef1L-4d9iA:
undetectable
5ef1V-4d9iA:
undetectable		 5ef1L-4d9iA:
11.42
5ef1V-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.14A 5ef1N-4d9iA:
undetectable
5ef1O-4d9iA:
undetectable		 5ef1N-4d9iA:
11.42
5ef1O-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		6 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
ALA A 131
 None
 1.32A 5ef1O-4d9iA:
undetectable
5ef1P-4d9iA:
undetectable		 5ef1O-4d9iA:
11.42
5ef1P-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.11A 5ef1P-4d9iA:
undetectable
5ef1Q-4d9iA:
undetectable		 5ef1P-4d9iA:
11.42
5ef1Q-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.11A 5ef1R-4d9iA:
undetectable
5ef1S-4d9iA:
undetectable		 5ef1R-4d9iA:
11.42
5ef1S-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.09A 5ef1S-4d9iA:
undetectable
5ef1T-4d9iA:
undetectable		 5ef1S-4d9iA:
11.42
5ef1T-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.11A 5ef1T-4d9iA:
undetectable
5ef1U-4d9iA:
undetectable		 5ef1T-4d9iA:
11.42
5ef1U-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.10A 5ef1U-4d9iA:
undetectable
5ef1V-4d9iA:
undetectable		 5ef1U-4d9iA:
11.42
5ef1V-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 9 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.07A 5ef2C-4d9iA:
undetectable
5ef2D-4d9iA:
undetectable		 5ef2C-4d9iA:
11.42
5ef2D-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.08A 5ef2G-4d9iA:
undetectable
5ef2H-4d9iA:
undetectable		 5ef2G-4d9iA:
11.42
5ef2H-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 11 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.07A 5ef2I-4d9iA:
undetectable
5ef2J-4d9iA:
undetectable		 5ef2I-4d9iA:
11.42
5ef2J-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		4 / 8 GLY A 121
ALA A 128
THR A 117
THR A 119
 None
 0.89A 5ef2L-4d9iA:
undetectable
5ef2V-4d9iA:
undetectable		 5ef2L-4d9iA:
11.42
5ef2V-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.13A 5ef2N-4d9iA:
undetectable
5ef2O-4d9iA:
undetectable		 5ef2N-4d9iA:
11.42
5ef2O-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		6 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
ALA A 131
 None
 1.31A 5ef2O-4d9iA:
undetectable
5ef2P-4d9iA:
undetectable		 5ef2O-4d9iA:
11.42
5ef2P-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.11A 5ef2P-4d9iA:
undetectable
5ef2Q-4d9iA:
undetectable		 5ef2P-4d9iA:
11.42
5ef2Q-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.11A 5ef2R-4d9iA:
undetectable
5ef2S-4d9iA:
undetectable		 5ef2R-4d9iA:
11.42
5ef2S-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.09A 5ef2S-4d9iA:
undetectable
5ef2T-4d9iA:
undetectable		 5ef2S-4d9iA:
11.42
5ef2T-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.11A 5ef2T-4d9iA:
undetectable
5ef2U-4d9iA:
undetectable		 5ef2T-4d9iA:
11.42
5ef2U-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.10A 5ef2U-4d9iA:
undetectable
5ef2V-4d9iA:
undetectable		 5ef2U-4d9iA:
11.42
5ef2V-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 9 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.07A 5ef3C-4d9iA:
undetectable
5ef3D-4d9iA:
undetectable		 5ef3C-4d9iA:
11.42
5ef3D-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.08A 5ef3G-4d9iA:
undetectable
5ef3H-4d9iA:
undetectable		 5ef3G-4d9iA:
11.42
5ef3H-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 11 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.07A 5ef3I-4d9iA:
undetectable
5ef3J-4d9iA:
undetectable		 5ef3I-4d9iA:
11.42
5ef3J-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.05A 5ef3A-4d9iA:
undetectable
5ef3K-4d9iA:
undetectable		 5ef3A-4d9iA:
11.42
5ef3K-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.14A 5ef3N-4d9iA:
undetectable
5ef3O-4d9iA:
undetectable		 5ef3N-4d9iA:
11.42
5ef3O-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		6 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
ALA A 131
 None
 1.31A 5ef3O-4d9iA:
undetectable
5ef3P-4d9iA:
undetectable		 5ef3O-4d9iA:
11.42
5ef3P-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.11A 5ef3P-4d9iA:
undetectable
5ef3Q-4d9iA:
undetectable		 5ef3P-4d9iA:
11.42
5ef3Q-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.11A 5ef3R-4d9iA:
undetectable
5ef3S-4d9iA:
undetectable		 5ef3R-4d9iA:
11.42
5ef3S-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.09A 5ef3S-4d9iA:
undetectable
5ef3T-4d9iA:
undetectable		 5ef3S-4d9iA:
11.42
5ef3T-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.11A 5ef3T-4d9iA:
undetectable
5ef3U-4d9iA:
undetectable		 5ef3T-4d9iA:
11.42
5ef3U-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 GLY A 124
HIS A 123
ALA A 138
THR A 117
ILE A 140
 None
 1.10A 5ef3U-4d9iA:
undetectable
5ef3V-4d9iA:
undetectable		 5ef3U-4d9iA:
11.42
5ef3V-4d9iA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1N_G_DVAG9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		3 / 3 ALA A 153
ASN A 156
LEU A 157
 None
 0.39A 5i1nB-4d9iA:
undetectable		 5i1nB-4d9iA:
6.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1O_H_DVAH9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		3 / 3 ALA A 153
ASN A 156
LEU A 157
 None
 0.46A 5i1oA-4d9iA:
undetectable		 5i1oA-4d9iA:
6.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1P_F_DVAF9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		3 / 3 ALA A 153
ASN A 156
LEU A 157
 None
 0.35A 5i1pA-4d9iA:
undetectable		 5i1pA-4d9iA:
7.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_A_CELA602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 12 VAL A  64
LEU A  50
GLY A 340
ALA A 341
LEU A 344
 None
None
LLP  A  77 ( 4.7A)
None
None
 1.04A 5jw1A-4d9iA:
undetectable		 5jw1A-4d9iA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_B_CHDB401_0
(BILE SALT HYDROLASE)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 LEU A 363
ILE A  62
LEU A  53
LEU A 319
ALA A 349
 None
 1.23A 5y7pB-4d9iA:
undetectable		 5y7pB-4d9iA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_D_CHDD401_0
(BILE SALT HYDROLASE)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 LEU A 363
ILE A  62
LEU A  53
LEU A 319
ALA A 349
 None
 1.22A 5y7pD-4d9iA:
undetectable		 5y7pD-4d9iA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_H_CHDH401_0
(BILE SALT HYDROLASE)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 LEU A 363
ILE A  62
LEU A  53
LEU A 319
ALA A 349
 None
 1.24A 5y7pH-4d9iA:
undetectable		 5y7pH-4d9iA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CBZ_B_ESTB602_1
(ESTROGEN RECEPTOR)		 4d9i DIAMINOPROPIONATE
AMMONIA-LYASE
(Escherichia
coli) 		5 / 10 ALA A 213
GLU A 212
ARG A  70
ILE A 334
LEU A  63
 None
 1.33A 6cbzB-4d9iA:
undetectable		 6cbzB-4d9iA:
12.60