SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4d9o'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NXU_A_RITA600_1
(CYTOCHROME P450 3A4)		 4d9o MEMBRANE-ASSOCIATED
PROTEIN VP24
(Reston
ebolavirus) 		5 / 12 LEU A 158
ALA A  43
ILE A 122
ALA A 118
GLU A 113
 None
 1.04A 3nxuA-4d9oA:
undetectable		 3nxuA-4d9oA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OND_A_ADNA506_2
(ADENOSYLHOMOCYSTEINA
SE)		 4d9o MEMBRANE-ASSOCIATED
PROTEIN VP24
(Reston
ebolavirus) 		3 / 3 GLN A  33
THR A  34
LEU A  94
 None
 0.29A 3ondA-4d9oA:
undetectable		 3ondA-4d9oA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OND_B_ADNB507_2
(ADENOSYLHOMOCYSTEINA
SE)		 4d9o MEMBRANE-ASSOCIATED
PROTEIN VP24
(Reston
ebolavirus) 		3 / 3 GLN A  33
THR A  34
LEU A  94
 None
 0.29A 3ondB-4d9oA:
undetectable		 3ondB-4d9oA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RD0_A_EDPA175_1
(FERRITIN LIGHT CHAIN)		 4d9o MEMBRANE-ASSOCIATED
PROTEIN VP24
(Reston
ebolavirus) 		4 / 6 LEU A  94
ALA A  99
ARG A  95
LEU A 222
 None
 1.10A 3rd0A-4d9oA:
undetectable		 3rd0A-4d9oA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_A_RITA401_2
(SECRETED ASPARTIC
PROTEASE)		 4d9o MEMBRANE-ASSOCIATED
PROTEIN VP24
(Reston
ebolavirus) 		4 / 6 SER A 123
VAL A 201
THR A 129
THR A 130
 None
 0.99A 3tneA-4d9oA:
undetectable		 3tneA-4d9oA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		 4d9o MEMBRANE-ASSOCIATED
PROTEIN VP24
(Reston
ebolavirus) 		4 / 8 ILE A 188
PHE A 160
LEU A 164
PHE A 227
 None
 0.90A 4qopC-4d9oA:
undetectable		 4qopC-4d9oA:
17.47