SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4dad'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_C_ACTC3004_0
(BETA-CARBONIC
ANHYDRASE)		 4dad PUTATIVE PILUS
ASSEMBLY-RELATED
PROTEIN
(Burkholderia
pseudomallei) 		4 / 6 TYR A  27
ASP A 113
VAL A  21
GLY A  25
 None
 1.07A 1ekjC-4dadA:
undetectable
1ekjD-4dadA:
2.6		 1ekjC-4dadA:
19.91
1ekjD-4dadA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_C_ACTC3007_0
(BETA-CARBONIC
ANHYDRASE)		 4dad PUTATIVE PILUS
ASSEMBLY-RELATED
PROTEIN
(Burkholderia
pseudomallei) 		4 / 6 ASP A 113
VAL A  21
GLY A  25
TYR A  27
 None
 1.12A 1ekjC-4dadA:
undetectable
1ekjD-4dadA:
2.6		 1ekjC-4dadA:
19.91
1ekjD-4dadA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KKZ_B_SAMB302_0
(UNCHARACTERIZED
PROTEIN Q5LES9)		 4dad PUTATIVE PILUS
ASSEMBLY-RELATED
PROTEIN
(Burkholderia
pseudomallei) 		5 / 12 ARG A  26
GLN A  -1
GLY A   0
GLY A  22
GLY A  25
 None
 0.90A 3kkzB-4dadA:
4.0		 3kkzB-4dadA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ7_B_SAMB302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 4dad PUTATIVE PILUS
ASSEMBLY-RELATED
PROTEIN
(Burkholderia
pseudomallei) 		5 / 12 LEU A  70
GLY A  34
ASP A  55
ALA A   7
LEU A   5
 None
 1.03A 3uj7B-4dadA:
4.3		 3uj7B-4dadA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B3Q_A_NVPA999_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 4dad PUTATIVE PILUS
ASSEMBLY-RELATED
PROTEIN
(Burkholderia
pseudomallei) 		4 / 7 LEU A 112
VAL A   6
TYR A  27
LEU A  80
 None
 1.09A 4b3qA-4dadA:
undetectable		 4b3qA-4dadA:
13.66