SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4dal'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4dal PUTATIVE ALDEHYDE
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 10 GLY A 350
ALA A 338
THR A 363
ILE A 346
GLY A 381
 None
None
None
None
GOL  A 600 (-4.6A)
 1.00A 1c9sN-4dalA:
undetectable
1c9sO-4dalA:
undetectable		 1c9sN-4dalA:
9.83
1c9sO-4dalA:
9.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4dal PUTATIVE ALDEHYDE
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 11 GLY A 350
ALA A 338
THR A 363
ILE A 346
GLY A 381
 None
None
None
None
GOL  A 600 (-4.6A)
 1.01A 1c9sP-4dalA:
undetectable
1c9sQ-4dalA:
undetectable		 1c9sP-4dalA:
9.83
1c9sQ-4dalA:
9.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4dal PUTATIVE ALDEHYDE
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 9 GLY A 350
ALA A 338
THR A 363
ILE A 346
GLY A 381
 None
None
None
None
GOL  A 600 (-4.6A)
 0.99A 1c9sQ-4dalA:
undetectable
1c9sR-4dalA:
undetectable		 1c9sQ-4dalA:
9.83
1c9sR-4dalA:
9.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4dal PUTATIVE ALDEHYDE
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 10 GLY A 381
GLY A 350
ALA A 338
THR A 363
ILE A 346
 GOL  A 600 (-4.6A)
None
None
None
None
 0.98A 1c9sL-4dalA:
undetectable
1c9sV-4dalA:
undetectable		 1c9sL-4dalA:
9.83
1c9sV-4dalA:
9.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4dal PUTATIVE ALDEHYDE
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 9 GLY A 381
GLY A 350
ALA A 338
THR A 363
ILE A 346
 GOL  A 600 (-4.6A)
None
None
None
None
 0.95A 1gtfD-4dalA:
undetectable
1gtfE-4dalA:
undetectable		 1gtfD-4dalA:
9.83
1gtfE-4dalA:
9.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4dal PUTATIVE ALDEHYDE
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 10 GLY A 381
GLY A 350
ALA A 338
THR A 363
ILE A 346
 GOL  A 600 (-4.6A)
None
None
None
None
 0.94A 1gtfJ-4dalA:
undetectable
1gtfK-4dalA:
undetectable		 1gtfJ-4dalA:
9.83
1gtfK-4dalA:
9.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4dal PUTATIVE ALDEHYDE
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 11 GLY A 350
ALA A 338
THR A 363
ILE A 346
GLY A 381
 None
None
None
None
GOL  A 600 (-4.6A)
 1.00A 1gtfQ-4dalA:
undetectable
1gtfR-4dalA:
undetectable		 1gtfQ-4dalA:
9.83
1gtfR-4dalA:
9.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_R_TRPR81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4dal PUTATIVE ALDEHYDE
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 9 GLY A 350
ALA A 338
THR A 363
ILE A 346
GLY A 381
 None
None
None
None
GOL  A 600 (-4.6A)
 1.01A 1gtfR-4dalA:
undetectable
1gtfS-4dalA:
undetectable		 1gtfR-4dalA:
9.83
1gtfS-4dalA:
9.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4dal PUTATIVE ALDEHYDE
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 11 GLY A 350
ALA A 338
THR A 363
ILE A 346
GLY A 381
 None
None
None
None
GOL  A 600 (-4.6A)
 1.00A 1gtfS-4dalA:
undetectable
1gtfT-4dalA:
undetectable		 1gtfS-4dalA:
9.83
1gtfT-4dalA:
9.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4dal PUTATIVE ALDEHYDE
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 11 GLY A 350
ALA A 338
THR A 363
ILE A 346
GLY A 381
 None
None
None
None
GOL  A 600 (-4.6A)
 0.99A 1gtnT-4dalA:
undetectable
1gtnU-4dalA:
undetectable		 1gtnT-4dalA:
9.83
1gtnU-4dalA:
9.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4dal PUTATIVE ALDEHYDE
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 12 GLY A 381
GLY A 350
ALA A 338
THR A 363
ILE A 346
 GOL  A 600 (-4.6A)
None
None
None
None
 0.98A 1gtnL-4dalA:
undetectable
1gtnV-4dalA:
undetectable		 1gtnL-4dalA:
9.83
1gtnV-4dalA:
9.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I6V_C_RFPC1640_1
(DNA-DIRECTED RNA
POLYMERASE)		 4dal PUTATIVE ALDEHYDE
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 12 LEU A 159
PHE A 110
ASP A 106
GLU A  75
ILE A  74
 None
 1.27A 1i6vC-4dalA:
0.0		 1i6vC-4dalA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N4H_A_REAA500_1
(NUCLEAR RECEPTOR
ROR-BETA)		 4dal PUTATIVE ALDEHYDE
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 11 ILE A 268
ALA A 283
VAL A 253
LEU A 261
ALA A 259
 None
 0.88A 1n4hA-4dalA:
undetectable		 1n4hA-4dalA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_E_TRPE81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4dal PUTATIVE ALDEHYDE
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 10 GLY A 350
ALA A 338
THR A 363
ILE A 346
GLY A 381
 None
None
None
None
GOL  A 600 (-4.6A)
 0.96A 1utdE-4dalA:
undetectable
1utdF-4dalA:
undetectable		 1utdE-4dalA:
9.83
1utdF-4dalA:
9.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_H_TRPH81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4dal PUTATIVE ALDEHYDE
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 10 GLY A 350
ALA A 338
THR A 363
ILE A 346
GLY A 381
 None
None
None
None
GOL  A 600 (-4.6A)
 0.93A 1utdH-4dalA:
undetectable
1utdI-4dalA:
undetectable		 1utdH-4dalA:
9.83
1utdI-4dalA:
9.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_L_TRPL81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4dal PUTATIVE ALDEHYDE
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 12 GLY A 350
ALA A 338
THR A 363
ILE A 346
GLY A 381
 None
None
None
None
GOL  A 600 (-4.6A)
 0.99A 1utdL-4dalA:
undetectable
1utdM-4dalA:
undetectable		 1utdL-4dalA:
9.83
1utdM-4dalA:
9.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_O_TRPO81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4dal PUTATIVE ALDEHYDE
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 12 GLY A 350
ALA A 338
THR A 363
ILE A 346
GLY A 381
 None
None
None
None
GOL  A 600 (-4.6A)
 0.98A 1utdO-4dalA:
undetectable
1utdP-4dalA:
undetectable		 1utdO-4dalA:
9.83
1utdP-4dalA:
9.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_P_TRPP81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4dal PUTATIVE ALDEHYDE
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 11 GLY A 350
ALA A 338
THR A 363
ILE A 346
GLY A 381
 None
None
None
None
GOL  A 600 (-4.6A)
 0.96A 1utdP-4dalA:
undetectable
1utdQ-4dalA:
undetectable		 1utdP-4dalA:
9.83
1utdQ-4dalA:
9.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_S_TRPS81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4dal PUTATIVE ALDEHYDE
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 11 GLY A 350
ALA A 338
THR A 363
ILE A 346
GLY A 381
 None
None
None
None
GOL  A 600 (-4.6A)
 0.97A 1utdS-4dalA:
undetectable
1utdT-4dalA:
undetectable		 1utdS-4dalA:
9.83
1utdT-4dalA:
9.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_U_TRPU81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4dal PUTATIVE ALDEHYDE
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 10 GLY A 350
ALA A 338
THR A 363
ILE A 346
GLY A 381
 None
None
None
None
GOL  A 600 (-4.6A)
 1.00A 1utdU-4dalA:
undetectable
1utdV-4dalA:
undetectable		 1utdU-4dalA:
9.83
1utdV-4dalA:
9.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_V_TRPV81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4dal PUTATIVE ALDEHYDE
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 11 GLY A 381
GLY A 350
ALA A 338
THR A 363
ILE A 346
 GOL  A 600 (-4.6A)
None
None
None
None
 0.98A 1utdL-4dalA:
undetectable
1utdV-4dalA:
undetectable		 1utdL-4dalA:
9.83
1utdV-4dalA:
9.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_C_SC2C1289_1
(FICOLIN-2)		 4dal PUTATIVE ALDEHYDE
DEHYDROGENASE
(Sinorhizobium
meliloti) 		4 / 6 SER A 402
SER A 450
LEU A 406
GLY A 405
 None
 0.96A 2j2pA-4dalA:
undetectable
2j2pC-4dalA:
undetectable		 2j2pA-4dalA:
18.45
2j2pC-4dalA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_F_SC2F1289_1
(FICOLIN-2)		 4dal PUTATIVE ALDEHYDE
DEHYDROGENASE
(Sinorhizobium
meliloti) 		4 / 6 SER A 402
SER A 450
LEU A 406
GLY A 405
 None
 0.96A 2j2pD-4dalA:
undetectable
2j2pF-4dalA:
undetectable		 2j2pD-4dalA:
18.45
2j2pF-4dalA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGN_A_PCFA1179_1
(WNT INHIBITORY
FACTOR 1)		 4dal PUTATIVE ALDEHYDE
DEHYDROGENASE
(Sinorhizobium
meliloti) 		4 / 5 ILE A 319
PHE A 436
PRO A 382
PHE A 380
 None
 1.06A 2ygnA-4dalA:
undetectable		 2ygnA-4dalA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A8I_A_C2FA401_0
(AMINOMETHYLTRANSFERA
SE)		 4dal PUTATIVE ALDEHYDE
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 12 TYR A 287
ILE A 254
TYR A 256
VAL A 410
TYR A 427
 None
 1.48A 3a8iA-4dalA:
undetectable		 3a8iA-4dalA:
25.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A8I_C_C2FC401_0
(AMINOMETHYLTRANSFERA
SE)		 4dal PUTATIVE ALDEHYDE
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 12 TYR A 287
ILE A 254
TYR A 256
VAL A 410
TYR A 427
 None
 1.49A 3a8iC-4dalA:
undetectable		 3a8iC-4dalA:
25.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A8I_D_C2FD401_0
(AMINOMETHYLTRANSFERA
SE)		 4dal PUTATIVE ALDEHYDE
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 12 TYR A 287
ILE A 254
TYR A 256
VAL A 410
TYR A 427
 None
 1.44A 3a8iD-4dalA:
undetectable		 3a8iD-4dalA:
25.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_C_SVRC505_2
(PHOSPHOLIPASE A2)		 4dal PUTATIVE ALDEHYDE
DEHYDROGENASE
(Sinorhizobium
meliloti) 		4 / 5 VAL A 384
VAL A 383
GLN A 361
ARG A 351
 None
 1.09A 3bjwH-4dalA:
undetectable		 3bjwH-4dalA:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_C_SVRC507_2
(PHOSPHOLIPASE A2)		 4dal PUTATIVE ALDEHYDE
DEHYDROGENASE
(Sinorhizobium
meliloti) 		4 / 6 VAL A 384
VAL A 383
GLN A 361
ARG A 351
 None
 1.12A 3bjwF-4dalA:
undetectable		 3bjwF-4dalA:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_G_SVRG506_2
(PHOSPHOLIPASE A2)		 4dal PUTATIVE ALDEHYDE
DEHYDROGENASE
(Sinorhizobium
meliloti) 		4 / 5 VAL A 384
VAL A 383
GLN A 361
ARG A 351
 None
 1.14A 3bjwB-4dalA:
undetectable		 3bjwB-4dalA:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CR5_X_PNTX95_0
(PROTEIN S100-B)		 4dal PUTATIVE ALDEHYDE
DEHYDROGENASE
(Sinorhizobium
meliloti) 		3 / 3 CYH A 107
PHE A 110
PHE A 111
 None
 0.90A 3cr5X-4dalA:
undetectable		 3cr5X-4dalA:
11.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LK0_D_Z80D92_1
(PROTEIN S100-B)		 4dal PUTATIVE ALDEHYDE
DEHYDROGENASE
(Sinorhizobium
meliloti) 		3 / 3 HIS A 444
PHE A 110
PHE A 111
 None
 0.68A 3lk0D-4dalA:
undetectable		 3lk0D-4dalA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RF4_A_FUNA201_1
(MACROPHAGE MIGRATION
INHIBITORY FACTOR)		 4dal PUTATIVE ALDEHYDE
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 11 PRO A 161
ILE A 163
VAL A 169
PHE A 171
VAL A 197
 None
 1.16A 3rf4A-4dalA:
undetectable
3rf4C-4dalA:
undetectable		 3rf4A-4dalA:
14.61
3rf4C-4dalA:
14.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RF4_B_FUNB202_1
(MACROPHAGE MIGRATION
INHIBITORY FACTOR)		 4dal PUTATIVE ALDEHYDE
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 11 PRO A 161
ILE A 163
VAL A 169
PHE A 171
VAL A 197
 None
 1.15A 3rf4A-4dalA:
undetectable
3rf4B-4dalA:
undetectable		 3rf4A-4dalA:
14.61
3rf4B-4dalA:
14.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RF4_C_FUNC203_1
(MACROPHAGE MIGRATION
INHIBITORY FACTOR)		 4dal PUTATIVE ALDEHYDE
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 11 PRO A 161
ILE A 163
VAL A 169
PHE A 171
VAL A 197
 None
 1.13A 3rf4B-4dalA:
undetectable
3rf4C-4dalA:
undetectable		 3rf4B-4dalA:
14.61
3rf4C-4dalA:
14.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGK_A_0TXA302_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 4dal PUTATIVE ALDEHYDE
DEHYDROGENASE
(Sinorhizobium
meliloti) 		4 / 7 GLY A 204
GLY A 208
ASN A 213
GLU A 175
 None
 1.04A 4fgkB-4dalA:
2.8		 4fgkB-4dalA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4H2F_A_ADNA601_1
(5'-NUCLEOTIDASE)		 4dal PUTATIVE ALDEHYDE
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 9 ASN A 167
GLY A 165
GLY A 166
ARG A  63
PHE A  52
 None
 1.43A 4h2fA-4dalA:
undetectable		 4h2fA-4dalA:
24.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4H2G_A_ADNA603_1
(5'-NUCLEOTIDASE)		 4dal PUTATIVE ALDEHYDE
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 9 ASN A 167
GLY A 165
GLY A 166
ARG A  63
PHE A  52
 None
 1.41A 4h2gA-4dalA:
undetectable		 4h2gA-4dalA:
24.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB301_1
(CHITOSANASE)		 4dal PUTATIVE ALDEHYDE
DEHYDROGENASE
(Sinorhizobium
meliloti) 		3 / 3 GLY A 320
PRO A 321
GLN A 278
 None
 0.31A 4oltB-4dalA:
undetectable		 4oltB-4dalA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB305_1
(CHITOSANASE)		 4dal PUTATIVE ALDEHYDE
DEHYDROGENASE
(Sinorhizobium
meliloti) 		3 / 3 GLY A 320
PRO A 321
GLN A 278
 None
 0.19A 4qwpB-4dalA:
undetectable		 4qwpB-4dalA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_A_URFA302_1
(URIDINE
PHOSPHORYLASE)		 4dal PUTATIVE ALDEHYDE
DEHYDROGENASE
(Sinorhizobium
meliloti) 		4 / 7 THR A 206
GLY A 208
ALA A 210
ILE A  41
 None
 0.90A 4txnA-4dalA:
undetectable		 4txnA-4dalA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_B_URFB302_1
(URIDINE
PHOSPHORYLASE)		 4dal PUTATIVE ALDEHYDE
DEHYDROGENASE
(Sinorhizobium
meliloti) 		4 / 7 THR A 206
GLY A 208
ALA A 210
ILE A  41
 None
 0.89A 4txnB-4dalA:
undetectable		 4txnB-4dalA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_C_URFC302_1
(URIDINE
PHOSPHORYLASE)		 4dal PUTATIVE ALDEHYDE
DEHYDROGENASE
(Sinorhizobium
meliloti) 		4 / 7 THR A 206
GLY A 208
ALA A 210
ILE A  41
 None
 0.86A 4txnC-4dalA:
undetectable		 4txnC-4dalA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_D_URFD302_1
(URIDINE
PHOSPHORYLASE)		 4dal PUTATIVE ALDEHYDE
DEHYDROGENASE
(Sinorhizobium
meliloti) 		4 / 7 THR A 206
GLY A 208
ALA A 210
ILE A  41
 None
 0.87A 4txnD-4dalA:
undetectable		 4txnD-4dalA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V1F_A_BQ1A1087_0
(F0F1 ATP SYNTHASE
SUBUNIT C)		 4dal PUTATIVE ALDEHYDE
DEHYDROGENASE
(Sinorhizobium
meliloti) 		3 / 3 GLU A  77
ALA A  78
PHE A  81
 None
 0.62A 4v1fA-4dalA:
undetectable		 4v1fA-4dalA:
11.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V1F_C_BQ1C1087_0
(F0F1 ATP SYNTHASE
SUBUNIT C)		 4dal PUTATIVE ALDEHYDE
DEHYDROGENASE
(Sinorhizobium
meliloti) 		3 / 3 GLU A  77
ALA A  78
PHE A  81
 None
 0.66A 4v1fC-4dalA:
undetectable		 4v1fC-4dalA:
11.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZO1_X_T3X500_1
(THYROID HORMONE
RECEPTOR BETA)		 4dal PUTATIVE ALDEHYDE
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 12 ALA A 399
ALA A 421
ARG A 424
ASN A 400
HIS A 435
 None
 1.25A 4zo1X-4dalA:
undetectable		 4zo1X-4dalA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECM_A_LEUA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 4dal PUTATIVE ALDEHYDE
DEHYDROGENASE
(Sinorhizobium
meliloti) 		4 / 5 THR A 369
ALA A 368
TYR A 293
HIS A 343
 None
 1.23A 5ecmA-4dalA:
undetectable		 5ecmA-4dalA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4dal PUTATIVE ALDEHYDE
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 10 GLY A 381
GLY A 350
ALA A 338
THR A 363
ILE A 346
 GOL  A 600 (-4.6A)
None
None
None
None
 0.96A 5eevA-4dalA:
undetectable
5eevB-4dalA:
undetectable		 5eevA-4dalA:
9.83
5eevB-4dalA:
9.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4dal PUTATIVE ALDEHYDE
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 10 GLY A 381
GLY A 350
ALA A 338
THR A 363
ILE A 346
 GOL  A 600 (-4.6A)
None
None
None
None
 0.96A 5eewA-4dalA:
undetectable
5eewB-4dalA:
undetectable		 5eewA-4dalA:
9.83
5eewB-4dalA:
9.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4dal PUTATIVE ALDEHYDE
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 10 GLY A 381
GLY A 350
ALA A 338
THR A 363
ILE A 346
 GOL  A 600 (-4.6A)
None
None
None
None
 0.96A 5eexA-4dalA:
undetectable
5eexB-4dalA:
undetectable		 5eexA-4dalA:
9.83
5eexB-4dalA:
9.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4dal PUTATIVE ALDEHYDE
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 10 GLY A 381
GLY A 350
ALA A 338
THR A 363
ILE A 346
 GOL  A 600 (-4.6A)
None
None
None
None
 0.96A 5eeyA-4dalA:
undetectable
5eeyB-4dalA:
undetectable		 5eeyA-4dalA:
9.83
5eeyB-4dalA:
9.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4dal PUTATIVE ALDEHYDE
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 10 GLY A 381
GLY A 350
ALA A 338
THR A 363
ILE A 346
 GOL  A 600 (-4.6A)
None
None
None
None
 0.96A 5eezA-4dalA:
undetectable
5eezB-4dalA:
undetectable		 5eezA-4dalA:
9.83
5eezB-4dalA:
9.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4dal PUTATIVE ALDEHYDE
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 10 GLY A 381
GLY A 350
ALA A 338
THR A 363
ILE A 346
 GOL  A 600 (-4.6A)
None
None
None
None
 0.96A 5ef0A-4dalA:
undetectable
5ef0B-4dalA:
undetectable		 5ef0A-4dalA:
9.83
5ef0B-4dalA:
9.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4dal PUTATIVE ALDEHYDE
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 10 GLY A 381
GLY A 350
ALA A 338
THR A 363
ILE A 346
 GOL  A 600 (-4.6A)
None
None
None
None
 0.96A 5ef1A-4dalA:
undetectable
5ef1B-4dalA:
undetectable		 5ef1A-4dalA:
9.83
5ef1B-4dalA:
9.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4dal PUTATIVE ALDEHYDE
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 10 GLY A 381
GLY A 350
ALA A 338
THR A 363
ILE A 346
 GOL  A 600 (-4.6A)
None
None
None
None
 0.96A 5ef2A-4dalA:
undetectable
5ef2B-4dalA:
undetectable		 5ef2A-4dalA:
9.83
5ef2B-4dalA:
9.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4dal PUTATIVE ALDEHYDE
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 10 GLY A 381
GLY A 350
ALA A 338
THR A 363
ILE A 346
 GOL  A 600 (-4.6A)
None
None
None
None
 0.96A 5ef3A-4dalA:
undetectable
5ef3B-4dalA:
undetectable		 5ef3A-4dalA:
9.83
5ef3B-4dalA:
9.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5FHZ_A_REAA602_1
(ALDEHYDE
DEHYDROGENASE FAMILY
1 MEMBER A3)		 4dal PUTATIVE ALDEHYDE
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 12 ASN A 149
MET A 154
TRP A 157
CYH A 280
THR A 281
 None
 0.53A 5fhzA-4dalA:
55.4		 5fhzA-4dalA:
35.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5FHZ_D_READ602_1
(ALDEHYDE
DEHYDROGENASE FAMILY
1 MEMBER A3)		 4dal PUTATIVE ALDEHYDE
DEHYDROGENASE
(Sinorhizobium
meliloti) 		7 / 12 ASN A 149
MET A 154
TRP A 157
GLU A 246
CYH A 280
THR A 281
LEU A 438
 None
 0.60A 5fhzD-4dalA:
32.7		 5fhzD-4dalA:
35.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K50_A_ACTA1403_0
(L-THREONINE
3-DEHYDROGENASE)		 4dal PUTATIVE ALDEHYDE
DEHYDROGENASE
(Sinorhizobium
meliloti) 		4 / 5 SER A 385
VAL A 365
GLY A 367
ALA A 368
 None
 0.98A 5k50A-4dalA:
4.5		 5k50A-4dalA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5D_B_SAMB303_0
(METHYLTRANSFERASE)		 4dal PUTATIVE ALDEHYDE
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 12 LEU A 300
ALA A 298
GLU A 345
ILE A 344
ALA A 338
 None
 1.04A 5n5dB-4dalA:
4.2		 5n5dB-4dalA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CI6_A_NBOA607_1
(SERUM ALBUMIN)		 4dal PUTATIVE ALDEHYDE
DEHYDROGENASE
(Sinorhizobium
meliloti) 		4 / 7 ASP A  79
ALA A  83
LYS A  97
LEU A 101
 None
 0.77A 6ci6A-4dalA:
undetectable		 6ci6A-4dalA:
8.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_A_GMJA301_1
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 4dal PUTATIVE ALDEHYDE
DEHYDROGENASE
(Sinorhizobium
meliloti) 		4 / 6 TYR A 287
ASP A 401
GLN A 426
THR A 387
 None
 1.35A 6djzA-4dalA:
undetectable		 6djzA-4dalA:
18.75