SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4dam'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2AA5_A_STRA301_1 (MINERALOCORTICOID RECEPTOR)	4dam	SINGLE-STRANDED DNA-BINDING PROTEIN 1 (Streptomyces coelicolor)	5 / 12	ASN A 58 LEU A 61 ALA A 62 SER A 66 LEU A 69	None	1.16A	2aa5A-4damA: undetectable	2aa5A-4damA: 19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2AA5_B_STRB302_1 (MINERALOCORTICOID RECEPTOR)	4dam	SINGLE-STRANDED DNA-BINDING PROTEIN 1 (Streptomyces coelicolor)	5 / 12	ASN A 58 LEU A 61 ALA A 62 SER A 66 LEU A 69	None	1.13A	2aa5B-4damA: undetectable	2aa5B-4damA: 19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3IB2_A_IBPA3960_1 (LACTOTRANSFERRIN)	4dam	SINGLE-STRANDED DNA-BINDING PROTEIN 1 (Streptomyces coelicolor)	4 / 4	GLY A 10 VAL A 75 GLY A 110 THR A 111	None	0.84A	3ib2A-4damA: undetectable	3ib2A-4damA: 16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DBY_A_ACTA617_0 (SERUM ALBUMIN)	4dam	SINGLE-STRANDED DNA-BINDING PROTEIN 1 (Streptomyces coelicolor)	3 / 3	TRP A 56 ARG A 28 LEU A 21	None	0.64A	5dbyA-4damA: undetectable	5dbyA-4damA: 11.84

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2AA5_A_STRA301_1","MINERALOCORTICOID RECEPTOR","4dam","SINGLE-STRANDED DNA-BINDING PROTEIN 1","Streptomyces coelicolor",5,"ASN A  58;LEU A  61;ALA A  62;SER A  66;LEU A  69","None","1.16A","2aa5A-4damA:undetectable","2aa5A-4damA:19.06"],["2AA5_B_STRB302_1","MINERALOCORTICOID RECEPTOR","4dam","SINGLE-STRANDED DNA-BINDING PROTEIN 1","Streptomyces coelicolor",5,"ASN A  58;LEU A  61;ALA A  62;SER A  66;LEU A  69","None","1.13A","2aa5B-4damA:undetectable","2aa5B-4damA:19.06"],["3IB2_A_IBPA3960_1","LACTOTRANSFERRIN","4dam","SINGLE-STRANDED DNA-BINDING PROTEIN 1","Streptomyces coelicolor",4,"GLY A  10;VAL A  75;GLY A 110;THR A 111","None","0.84A","3ib2A-4damA:undetectable","3ib2A-4damA:16.09"],["5DBY_A_ACTA617_0","SERUM ALBUMIN","4dam","SINGLE-STRANDED DNA-BINDING PROTEIN 1","Streptomyces coelicolor",3,"TRP A  56;ARG A  28;LEU A  21","None","0.64A","5dbyA-4damA:undetectable","5dbyA-4damA:11.84"]]