SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4db1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C6Y_B_MK1B524_2
(PROTEIN (PROTEASE))		 4db1 MYOSIN-7
(Homo
sapiens) 		5 / 12 ALA A 261
ASP A 262
GLY A 458
ILE A 457
ILE A 220
 None
 0.84A 1c6yB-4db1A:
undetectable		 1c6yB-4db1A:
7.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FAP_A_RAPA108_1
(FK506-BINDING
PROTEIN)		 4db1 MYOSIN-7
(Homo
sapiens) 		5 / 12 ASP A 461
GLU A 328
ILE A 248
ILE A 263
PHE A 244
 MN  A 802 ( 4.1A)
None
None
None
None
 1.03A 1fapA-4db1A:
undetectable		 1fapA-4db1A:
8.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FKL_A_RAPA108_1
(FK506 BINDING
PROTEIN)		 4db1 MYOSIN-7
(Homo
sapiens) 		5 / 12 ASP A 461
GLU A 328
ILE A 248
ILE A 263
PHE A 244
 MN  A 802 ( 4.1A)
None
None
None
None
 0.95A 1fklA-4db1A:
undetectable		 1fklA-4db1A:
9.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		 4db1 MYOSIN-7
(Homo
sapiens) 		4 / 8 SER A 173
THR A 481
ASN A 654
LEU A 175
 None
 1.00A 1lhvA-4db1A:
undetectable		 1lhvA-4db1A:
12.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MUI_B_AB1B100_1
(PROTEASE)		 4db1 MYOSIN-7
(Homo
sapiens) 		5 / 10 ALA A 261
ASP A 262
GLY A 458
ILE A 457
ILE A 220
 None
 0.97A 1muiA-4db1A:
undetectable		 1muiA-4db1A:
7.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RL8_A_RITA9001_2
(PROTEASE RETROPEPSIN)		 4db1 MYOSIN-7
(Homo
sapiens) 		6 / 12 ALA A 261
ASP A 262
GLY A 458
ILE A 457
ALA A 196
ILE A 220
 None
 1.43A 1rl8B-4db1A:
undetectable		 1rl8B-4db1A:
8.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDV_B_MK1B902_2
(PROTEASE RETROPEPSIN)		 4db1 MYOSIN-7
(Homo
sapiens) 		5 / 11 ALA A 261
ASP A 262
GLY A 458
ILE A 457
ILE A 220
 None
 0.87A 1sdvB-4db1A:
undetectable		 1sdvB-4db1A:
7.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IDW_B_017B401_2
(PROTEASE)		 4db1 MYOSIN-7
(Homo
sapiens) 		5 / 9 ALA A 261
ASP A 262
GLY A 458
ILE A 457
ILE A 220
 None
 0.85A 2idwB-4db1A:
undetectable		 2idwB-4db1A:
7.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q5K_A_AB1A201_1
(PROTEASE)		 4db1 MYOSIN-7
(Homo
sapiens) 		5 / 9 ALA A 261
ASP A 262
GLY A 458
ILE A 457
ILE A 220
 None
 0.79A 2q5kA-4db1A:
undetectable		 2q5kA-4db1A:
8.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHC_B_AB1B9001_1
(PROTEASE RETROPEPSIN)		 4db1 MYOSIN-7
(Homo
sapiens) 		5 / 11 ALA A 261
ASP A 262
GLY A 458
ILE A 457
ILE A 220
 None
 1.00A 2qhcA-4db1A:
undetectable		 2qhcA-4db1A:
7.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5P_D_MK1D902_2
(PROTEASE)		 4db1 MYOSIN-7
(Homo
sapiens) 		5 / 12 ALA A 261
ASP A 262
GLY A 458
ILE A 457
ILE A 220
 None
 0.88A 2r5pD-4db1A:
undetectable		 2r5pD-4db1A:
8.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_D_1UND900_2
(PROTEASE)		 4db1 MYOSIN-7
(Homo
sapiens) 		5 / 10 ALA A 261
ASP A 262
GLY A 458
ILE A 457
ILE A 220
 None
 0.90A 2r5qD-4db1A:
undetectable		 2r5qD-4db1A:
8.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_D_TOPD1158_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 4db1 MYOSIN-7
(Homo
sapiens) 		5 / 10 ILE A 192
ALA A 223
LEU A 227
ILE A 248
SER A 242
 None
None
None
None
MN  A 802 ( 2.2A)
 1.09A 2w9sD-4db1A:
undetectable		 2w9sD-4db1A:
12.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_F_TOPF1159_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 4db1 MYOSIN-7
(Homo
sapiens) 		5 / 10 ILE A 192
ALA A 223
LEU A 227
ILE A 248
SER A 242
 None
None
None
None
MN  A 802 ( 2.2A)
 1.08A 2w9sF-4db1A:
undetectable		 2w9sF-4db1A:
12.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKQ_A_ROCA100_1
(PROTEASE)		 4db1 MYOSIN-7
(Homo
sapiens) 		5 / 12 ALA A 261
ASP A 262
GLY A 458
ILE A 457
ILE A 220
 None
 0.88A 3ekqA-4db1A:
undetectable		 3ekqA-4db1A:
7.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKV_A_478A200_1
(PROTEASE)		 4db1 MYOSIN-7
(Homo
sapiens) 		5 / 10 ALA A 261
ASP A 262
GLY A 458
ILE A 457
ILE A 220
 None
 0.76A 3ekvA-4db1A:
undetectable		 3ekvA-4db1A:
8.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKW_B_DR7B100_1
(PROTEASE)		 4db1 MYOSIN-7
(Homo
sapiens) 		6 / 10 ALA A 261
ASP A 262
GLY A 458
ILE A 457
ALA A 196
ILE A 220
 None
 1.29A 3ekwA-4db1A:
undetectable		 3ekwA-4db1A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKY_A_DR7A100_1
(PROTEASE)		 4db1 MYOSIN-7
(Homo
sapiens) 		5 / 10 ALA A 261
ASP A 262
GLY A 458
ILE A 457
ILE A 220
 None
 0.98A 3ekyA-4db1A:
undetectable		 3ekyA-4db1A:
8.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_A_H3PA552_1
(GLUTAMATE
DEHYDROGENASE)		 4db1 MYOSIN-7
(Homo
sapiens) 		4 / 6 ILE A 313
TYR A 283
ILE A 356
HIS A 358
 None
 0.98A 3eteA-4db1A:
undetectable
3eteE-4db1A:
undetectable		 3eteA-4db1A:
20.72
3eteE-4db1A:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_C_H3PC554_1
(GLUTAMATE
DEHYDROGENASE)		 4db1 MYOSIN-7
(Homo
sapiens) 		4 / 5 ILE A 313
TYR A 283
ILE A 356
HIS A 358
 None
 0.96A 3eteB-4db1A:
undetectable
3eteC-4db1A:
undetectable		 3eteB-4db1A:
20.72
3eteC-4db1A:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_F_H3PF552_1
(GLUTAMATE
DEHYDROGENASE)		 4db1 MYOSIN-7
(Homo
sapiens) 		4 / 7 ILE A 356
HIS A 358
ILE A 313
TYR A 283
 None
 0.97A 3eteD-4db1A:
undetectable
3eteF-4db1A:
undetectable		 3eteD-4db1A:
20.72
3eteF-4db1A:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDW_A_RITA100_2
(PROTEASE)		 4db1 MYOSIN-7
(Homo
sapiens) 		5 / 9 ALA A 261
ASP A 262
GLY A 458
ILE A 457
ILE A 220
 None
 1.04A 3ndwB-4db1A:
undetectable		 3ndwB-4db1A:
7.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NRR_A_D16A520_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 4db1 MYOSIN-7
(Homo
sapiens) 		5 / 12 ALA A  11
ARG A 190
ILE A 114
PRO A 127
LEU A  16
 None
None
None
ANP  A 801 (-4.2A)
None
 1.22A 3nrrA-4db1A:
undetectable		 3nrrA-4db1A:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGP_A_017A200_1
(FIV PROTEASE)		 4db1 MYOSIN-7
(Homo
sapiens) 		5 / 9 ALA A 261
ASP A 262
ILE A 263
GLY A 458
ILE A 457
 None
 0.96A 3ogpA-4db1A:
undetectable		 3ogpA-4db1A:
11.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGH_B_FLPB701_1
(CYCLOOXYGENASE-2)		 4db1 MYOSIN-7
(Homo
sapiens) 		5 / 11 LEU A 614
TYR A 609
LEU A 390
GLY A 354
ALA A 355
 None
 1.21A 3pghB-4db1A:
undetectable		 3pghB-4db1A:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TTP_A_017A201_1
(HIV-1 PROTEASE)		 4db1 MYOSIN-7
(Homo
sapiens) 		5 / 10 ALA A 261
ASP A 262
GLY A 458
ILE A 457
ILE A 220
 None
 0.90A 3ttpA-4db1A:
undetectable		 3ttpA-4db1A:
9.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TTP_A_017A201_2
(HIV-1 PROTEASE)		 4db1 MYOSIN-7
(Homo
sapiens) 		5 / 10 ALA A 261
ASP A 262
GLY A 458
ILE A 457
ILE A 220
 None
 0.91A 3ttpB-4db1A:
undetectable		 3ttpB-4db1A:
9.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQF_B_017B101_2
(ASPARTYL PROTEASE)		 4db1 MYOSIN-7
(Homo
sapiens) 		5 / 10 ALA A 261
ASP A 262
GLY A 458
ILE A 457
ILE A 220
 None
 0.84A 4dqfB-4db1A:
undetectable		 4dqfB-4db1A:
7.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G2Z_A_ID8A711_1
(LACTOTRANSFERRIN)		 4db1 MYOSIN-7
(Homo
sapiens) 		3 / 3 PRO A 675
TYR A 128
GLY A 682
 None
ANP  A 801 ( 4.6A)
None
 0.72A 4g2zA-4db1A:
undetectable		 4g2zA-4db1A:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LL3_A_017A201_2
(PROTEASE)		 4db1 MYOSIN-7
(Homo
sapiens) 		5 / 10 ALA A 261
ASP A 262
GLY A 458
ILE A 457
ILE A 220
 None
 0.90A 4ll3B-4db1A:
undetectable		 4ll3B-4db1A:
8.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LL3_A_017A202_1
(PROTEASE)		 4db1 MYOSIN-7
(Homo
sapiens) 		5 / 10 ALA A 261
ASP A 262
GLY A 458
ILE A 457
ILE A 220
 None
 0.88A 4ll3A-4db1A:
undetectable		 4ll3A-4db1A:
8.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OU1_A_BEZA302_0
(RETRO-ALDOLASE,
DESIGN RA114)		 4db1 MYOSIN-7
(Homo
sapiens) 		5 / 8 ILE A 192
LYS A 189
ILE A 220
ASN A 224
ALA A 223
 None
 1.23A 4ou1A-4db1A:
undetectable		 4ou1A-4db1A:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R21_A_STRA601_1
(CYTOCHROME P450
FAMILY 17
POLYPEPTIDE 2)		 4db1 MYOSIN-7
(Homo
sapiens) 		4 / 6 ALA A 261
GLY A 458
ILE A 220
VAL A 191
 None
 0.70A 4r21A-4db1A:
1.2		 4r21A-4db1A:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_C_CHDC102_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 4db1 MYOSIN-7
(Homo
sapiens) 		4 / 7 LYS A 106
LEU A 105
ASN A 686
LEU A 693
 None
 0.77A 4wg0B-4db1A:
undetectable
4wg0C-4db1A:
undetectable		 4wg0B-4db1A:
2.17
4wg0C-4db1A:
2.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_L_CHDL103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 4db1 MYOSIN-7
(Homo
sapiens) 		4 / 7 ASN A 686
LEU A 693
LYS A 106
LEU A 105
 None
 0.79A 4wg0L-4db1A:
undetectable
4wg0M-4db1A:
undetectable		 4wg0L-4db1A:
2.17
4wg0M-4db1A:
2.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WRY_A_URFA302_1
(URACIL-DNA
GLYCOSYLASE)		 4db1 MYOSIN-7
(Homo
sapiens) 		4 / 8 GLY A 697
PHE A 121
SER A 118
ASN A 696
 None
 1.04A 4wryA-4db1A:
undetectable		 4wryA-4db1A:
13.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WS1_A_URFA301_1
(URACIL-DNA
GLYCOSYLASE)		 4db1 MYOSIN-7
(Homo
sapiens) 		4 / 8 GLY A 697
PHE A 121
SER A 118
ASN A 696
 None
 1.00A 4ws1A-4db1A:
undetectable		 4ws1A-4db1A:
13.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_E_4LEE401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 4db1 MYOSIN-7
(Homo
sapiens) 		4 / 7 THR A 619
LEU A 620
LEU A 616
THR A 441
 None
 0.68A 4z90A-4db1A:
2.8
4z90B-4db1A:
undetectable
4z90C-4db1A:
undetectable
4z90D-4db1A:
undetectable
4z90E-4db1A:
undetectable		 4z90A-4db1A:
17.34
4z90B-4db1A:
17.34
4z90C-4db1A:
17.34
4z90D-4db1A:
17.34
4z90E-4db1A:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_F_4LEF401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 4db1 MYOSIN-7
(Homo
sapiens) 		4 / 8 LEU A 616
THR A 441
THR A 619
LEU A 620
 None
 0.65A 4z90F-4db1A:
undetectable
4z90G-4db1A:
undetectable
4z90H-4db1A:
undetectable
4z90I-4db1A:
undetectable
4z90J-4db1A:
undetectable		 4z90F-4db1A:
17.34
4z90G-4db1A:
17.34
4z90H-4db1A:
17.34
4z90I-4db1A:
17.34
4z90J-4db1A:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_F_4LEF401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 4db1 MYOSIN-7
(Homo
sapiens) 		4 / 8 THR A 441
THR A 619
LEU A 620
LEU A 616
 None
 0.63A 4z90F-4db1A:
undetectable
4z90G-4db1A:
undetectable
4z90H-4db1A:
undetectable
4z90I-4db1A:
undetectable
4z90J-4db1A:
undetectable		 4z90F-4db1A:
17.34
4z90G-4db1A:
17.34
4z90H-4db1A:
17.34
4z90I-4db1A:
17.34
4z90J-4db1A:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZDZ_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4db1 MYOSIN-7
(Homo
sapiens) 		4 / 7 PHE A 312
ILE A 356
GLY A 425
LEU A 399
 None
 0.80A 4zdzA-4db1A:
1.6		 4zdzA-4db1A:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE3_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4db1 MYOSIN-7
(Homo
sapiens) 		4 / 7 PHE A 312
ILE A 356
GLY A 425
LEU A 399
 None
 0.81A 4ze3A-4db1A:
undetectable		 4ze3A-4db1A:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESF_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4db1 MYOSIN-7
(Homo
sapiens) 		4 / 8 PHE A 312
ILE A 356
GLY A 425
LEU A 399
 None
 0.77A 5esfA-4db1A:
0.8		 5esfA-4db1A:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESJ_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4db1 MYOSIN-7
(Homo
sapiens) 		4 / 8 PHE A 312
ILE A 356
GLY A 425
LEU A 399
 None
 0.81A 5esjA-4db1A:
undetectable		 5esjA-4db1A:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESM_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4db1 MYOSIN-7
(Homo
sapiens) 		4 / 7 PHE A 312
ILE A 356
GLY A 425
LEU A 399
 None
 0.79A 5esmA-4db1A:
undetectable		 5esmA-4db1A:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HS1_A_VORA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4db1 MYOSIN-7
(Homo
sapiens) 		4 / 8 PHE A 312
ILE A 356
GLY A 425
LEU A 399
 None
 0.88A 5hs1A-4db1A:
undetectable		 5hs1A-4db1A:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4T_A_BEZA507_0
(BETA-LACTAMASE VIM-2)		 4db1 MYOSIN-7
(Homo
sapiens) 		3 / 3 THR A 481
HIS A 651
ASN A 654
 None
 0.89A 5n4tA-4db1A:
undetectable		 5n4tA-4db1A:
14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_A_CUA604_0
(THIOCYANATE
DEHYDROGENASE)		 4db1 MYOSIN-7
(Homo
sapiens) 		3 / 3 HIS A 492
HIS A 666
HIS A 668
 None
 0.97A 5oexA-4db1A:
undetectable		 5oexA-4db1A:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T2Z_B_017B201_2
(PROTEASE)		 4db1 MYOSIN-7
(Homo
sapiens) 		5 / 12 ALA A 261
ASP A 262
GLY A 458
ILE A 457
ILE A 220
 None
 0.83A 5t2zB-4db1A:
undetectable		 5t2zB-4db1A:
8.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8H_B_478B401_1
(PROTEASE)		 4db1 MYOSIN-7
(Homo
sapiens) 		5 / 12 ALA A 261
ASP A 262
GLY A 458
ILE A 457
ILE A 220
 None
 0.78A 5t8hA-4db1A:
undetectable		 5t8hA-4db1A:
8.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA501_1
(CYTOCHROME P450 2C9)		 4db1 MYOSIN-7
(Homo
sapiens) 		5 / 12 ALA A 430
VAL A 273
GLY A 360
LEU A 396
LEU A 399
 None
 1.06A 5xxiA-4db1A:
undetectable		 5xxiA-4db1A:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YBB_A_SAMA601_1
(TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT)		 4db1 MYOSIN-7
(Homo
sapiens) 		4 / 5 PHE A 247
THR A 660
GLU A 264
ASN A 437
 None
 1.28A 5ybbA-4db1A:
0.7		 5ybbA-4db1A:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRF_D_EVPD101_1
()		 4db1 MYOSIN-7
(Homo
sapiens) 		4 / 5 GLY A   2
ASP A   3
ARG A  17
GLN A  27
 None
 1.40A 5zrfB-4db1A:
undetectable		 5zrfB-4db1A:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA603_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 4db1 MYOSIN-7
(Homo
sapiens) 		3 / 3 TYR A 609
ASN A 602
LEU A 427
 None
 0.45A 6b58A-4db1A:
undetectable		 6b58A-4db1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJ2_B_AB1B201_0
(HIV-1 PROTEASE)		 4db1 MYOSIN-7
(Homo
sapiens) 		5 / 10 ALA A 261
ASP A 262
GLY A 458
ILE A 457
ILE A 220
 None
 0.87A 6dj2A-4db1A:
undetectable		 6dj2A-4db1A:
7.23