SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4dbg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_A_SNLA1001_2
(MINERALOCORTICOID
RECEPTOR)		 4dbg RANBP-TYPE AND
C3HC4-TYPE ZINC
FINGER-CONTAINING
PROTEIN 1
(Homo
sapiens) 		4 / 5 LEU A 128
ALA A 126
LEU A  57
MET A  87
 None
 1.13A 2oaxA-4dbgA:
undetectable		 2oaxA-4dbgA:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I13_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 4dbg RANBP-TYPE AND
C3HC4-TYPE ZINC
FINGER-CONTAINING
PROTEIN 1
RING FINGER PROTEIN
31
(Homo
sapiens;
Homo
sapiens) 		3 / 3 ASP A  91
ARG A  76
THR B 610
 None
 0.89A 4i13A-4dbgA:
undetectable		 4i13A-4dbgA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P3R_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 4dbg RANBP-TYPE AND
C3HC4-TYPE ZINC
FINGER-CONTAINING
PROTEIN 1
RING FINGER PROTEIN
31
(Homo
sapiens;
Homo
sapiens) 		3 / 3 ASP A  91
ARG A  76
THR B 610
 None
 0.88A 4p3rA-4dbgA:
undetectable		 4p3rA-4dbgA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EU9_B_REAB601_1
(RETINOIC ACID
RECEPTOR)		 4dbg RING FINGER PROTEIN
31
(Homo
sapiens) 		5 / 10 ARG B 577
VAL B 580
LEU B 612
GLY B 545
GLY B 593
 None
 1.15A 6eu9B-4dbgB:
undetectable		 6eu9B-4dbgB:
19.75