SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ddp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BDW_A_DVAA6_0
(GRAMICIDIN A)		 4ddp BECLIN-1
(Homo
sapiens) 		3 / 3 ALA A 441
VAL A 443
TRP A 442
 None
 0.78A 1bdwA-4ddpA:
undetectable
1bdwB-4ddpA:
undetectable		 1bdwA-4ddpA:
5.15
1bdwB-4ddpA:
5.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZZ_A_ACTA421_0
(ACLACINOMYCIN-10-HYD
ROXYLASE)		 4ddp BECLIN-1
(Homo
sapiens) 		4 / 8 TYR A 413
GLY A 408
GLY A 410
GLY A 411
 None
 0.56A 1qzzA-4ddpA:
undetectable		 1qzzA-4ddpA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_A_ACTA609_0
(GBAA_1210 PROTEIN)		 4ddp BECLIN-1
(Homo
sapiens) 		3 / 3 LYS A 416
VAL A 370
HIS A 367
 None
 0.61A 3tj7A-4ddpA:
undetectable		 3tj7A-4ddpA:
21.85