SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4dey'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZLC_A_VDXA500_1 (VITAMIN D3 RECEPTOR)	4dey	VOLTAGE-DEPENDENT L-TYPE CALCIUM CHANNEL SUBUNIT BETA-2 (Oryctolagus cuniculus)	5 / 12	VAL A 224 SER A 334 VAL A 96 HIS A 95 LEU A 314	None BR A 512 (-4.6A) None None None	1.28A	2zlcA-4deyA: undetectable	2zlcA-4deyA: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4W5O_A_IPHA906_0 (PROTEIN ARGONAUTE-2)	4dey	VOLTAGE-DEPENDENT L-TYPE CALCIUM CHANNEL SUBUNIT BETA-2 (Oryctolagus cuniculus)	4 / 5	PHE A 63 PRO A 225 VAL A 223 ALA A 64	None	1.31A	4w5oA-4deyA: 4.5	4w5oA-4deyA: 17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DPD_B_SAMB601_0 (PROTEIN LYSINE METHYLTRANSFERASE 1)	4dey	VOLTAGE-DEPENDENT L-TYPE CALCIUM CHANNEL SUBUNIT BETA-2 (Oryctolagus cuniculus)	5 / 12	LEU A 335 SER A 334 ILE A 324 VAL A 339 VAL A 231	None BR A 512 (-4.6A) None None None	1.17A	5dpdB-4deyA: undetectable	5dpdB-4deyA: 20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MVN_B_PFLB410_1 (PROTON-GATED ION CHANNEL)	4dey	VOLTAGE-DEPENDENT L-TYPE CALCIUM CHANNEL SUBUNIT BETA-2 (Oryctolagus cuniculus)	5 / 9	PRO A 120 TYR A 71 ILE A 86 VAL A 79 ILE A 106	None None BR A 510 ( 4.2A) BR A 502 (-4.6A) None	1.25A	5mvnB-4deyA: undetectable	5mvnB-4deyA: 11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MVN_D_PFLD410_1 (PROTON-GATED ION CHANNEL)	4dey	VOLTAGE-DEPENDENT L-TYPE CALCIUM CHANNEL SUBUNIT BETA-2 (Oryctolagus cuniculus)	5 / 10	PRO A 120 TYR A 71 ILE A 86 VAL A 79 ILE A 106	None None BR A 510 ( 4.2A) BR A 502 (-4.6A) None	1.25A	5mvnD-4deyA: undetectable	5mvnD-4deyA: 11.90

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2ZLC_A_VDXA500_1","VITAMIN D3 RECEPTOR","4dey","VOLTAGE-DEPENDENT L-TYPE CALCIUM CHANNEL SUBUNIT BETA-2","Oryctolagus cuniculus",5,"VAL A 224;SER A 334;VAL A  96;HIS A  95;LEU A 314","None; BR A 512 (-4.6A);None;None;None","1.28A","2zlcA-4deyA:undetectable","2zlcA-4deyA:20.00"],["4W5O_A_IPHA906_0","PROTEIN ARGONAUTE-2","4dey","VOLTAGE-DEPENDENT L-TYPE CALCIUM CHANNEL SUBUNIT BETA-2","Oryctolagus cuniculus",4,"PHE A  63;PRO A 225;VAL A 223;ALA A  64","None","1.31A","4w5oA-4deyA:4.5","4w5oA-4deyA:17.48"],["5DPD_B_SAMB601_0","PROTEIN LYSINE METHYLTRANSFERASE 1","4dey","VOLTAGE-DEPENDENT L-TYPE CALCIUM CHANNEL SUBUNIT BETA-2","Oryctolagus cuniculus",5,"LEU A 335;SER A 334;ILE A 324;VAL A 339;VAL A 231","None; BR A 512 (-4.6A);None;None;None","1.17A","5dpdB-4deyA:undetectable","5dpdB-4deyA:20.07"],["5MVN_B_PFLB410_1","PROTON-GATED ION CHANNEL","4dey","VOLTAGE-DEPENDENT L-TYPE CALCIUM CHANNEL SUBUNIT BETA-2","Oryctolagus cuniculus",5,"PRO A 120;TYR A  71;ILE A  86;VAL A  79;ILE A 106","None;None; BR A 510 ( 4.2A); BR A 502 (-4.6A);None","1.25A","5mvnB-4deyA:undetectable","5mvnB-4deyA:11.90"],["5MVN_D_PFLD410_1","PROTON-GATED ION CHANNEL","4dey","VOLTAGE-DEPENDENT L-TYPE CALCIUM CHANNEL SUBUNIT BETA-2","Oryctolagus cuniculus",5,"PRO A 120;TYR A  71;ILE A  86;VAL A  79;ILE A 106","None;None; BR A 510 ( 4.2A); BR A 502 (-4.6A);None","1.25A","5mvnD-4deyA:undetectable","5mvnD-4deyA:11.90"]]