SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4dgk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_1
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		4 / 4 THR A 324
LEU A 352
VAL A 372
LEU A 309
 None
 1.11A 1fbmB-4dgkA:
undetectable		 1fbmB-4dgkA:
7.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I9G_A_SAMA301_0
(HYPOTHETICAL PROTEIN
RV2118C)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		5 / 12 GLY A   8
GLY A  10
ALA A  15
LEU A  16
VAL A 244
 None
 1.11A 1i9gA-4dgkA:
undetectable		 1i9gA-4dgkA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_A_BEZA349_0
(D-AMINO ACID OXIDASE)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		4 / 5 TYR A 136
TYR A 201
ILE A 204
GLY A 135
 None
 1.33A 1kifA-4dgkA:
10.3		 1kifA-4dgkA:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_B_BEZB349_0
(D-AMINO ACID OXIDASE)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		4 / 5 TYR A 136
TYR A 201
ILE A 204
GLY A 135
 None
 1.33A 1kifB-4dgkA:
10.7		 1kifB-4dgkA:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_C_BEZC349_0
(D-AMINO ACID OXIDASE)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		4 / 5 TYR A 136
TYR A 201
ILE A 204
GLY A 135
 None
 1.33A 1kifC-4dgkA:
10.6		 1kifC-4dgkA:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_D_BEZD349_0
(D-AMINO ACID OXIDASE)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		4 / 5 TYR A 136
TYR A 201
ILE A 204
GLY A 135
 None
 1.33A 1kifD-4dgkA:
10.4		 1kifD-4dgkA:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_E_BEZE349_0
(D-AMINO ACID OXIDASE)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		4 / 5 TYR A 136
TYR A 201
ILE A 204
GLY A 135
 None
 1.33A 1kifE-4dgkA:
10.4		 1kifE-4dgkA:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_F_BEZF349_0
(D-AMINO ACID OXIDASE)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		4 / 5 TYR A 136
TYR A 201
ILE A 204
GLY A 135
 None
 1.33A 1kifF-4dgkA:
10.6		 1kifF-4dgkA:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_G_BEZG349_0
(D-AMINO ACID OXIDASE)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		4 / 5 TYR A 136
TYR A 201
ILE A 204
GLY A 135
 None
 1.33A 1kifG-4dgkA:
10.6		 1kifG-4dgkA:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_H_BEZH349_0
(D-AMINO ACID OXIDASE)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		4 / 5 TYR A 136
TYR A 201
ILE A 204
GLY A 135
 None
 1.33A 1kifH-4dgkA:
10.4		 1kifH-4dgkA:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TMX_B_BEZB882_0
(HYDROXYQUINOL
1,2-DIOXYGENASE)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		5 / 12 LEU A 223
ILE A  57
HIS A 323
HIS A 353
HIS A 322
 None
None
None
EDO  A 602 (-3.8A)
None
 1.13A 1tmxB-4dgkA:
undetectable		 1tmxB-4dgkA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UKB_A_BEZA1301_0
(2-HYDROXY-6-OXO-7-ME
THYLOCTA-2,4-DIENOAT
E HYDROLASE)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		4 / 6 LEU A 401
PHE A 398
ALA A 399
LEU A 350
 None
 0.94A 1ukbA-4dgkA:
undetectable		 1ukbA-4dgkA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_C_CHDC3525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		4 / 7 HIS A 323
ASP A  59
THR A  58
HIS A 353
 None
None
None
EDO  A 602 (-3.8A)
 1.47A 1v54A-4dgkA:
undetectable
1v54C-4dgkA:
undetectable		 1v54A-4dgkA:
23.01
1v54C-4dgkA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_C_CHDC3525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		4 / 7 HIS A 323
ASP A  59
THR A  58
HIS A 353
 None
None
None
EDO  A 602 (-3.8A)
 1.47A 1v55A-4dgkA:
undetectable
1v55C-4dgkA:
undetectable		 1v55A-4dgkA:
23.01
1v55C-4dgkA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YDB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		5 / 11 HIS A 322
HIS A 353
HIS A 323
VAL A 213
THR A  55
 None
EDO  A 602 (-3.8A)
None
None
None
 1.28A 1ydbA-4dgkA:
undetectable		 1ydbA-4dgkA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YDB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		5 / 11 HIS A 322
HIS A 353
VAL A  83
VAL A 213
THR A  55
 None
EDO  A 602 (-3.8A)
EDO  A 601 ( 3.9A)
None
None
 1.35A 1ydbA-4dgkA:
undetectable		 1ydbA-4dgkA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_A_NFZA1219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		4 / 8 PHE A  50
GLY A 219
THR A 358
PHE A 215
 None
None
EDO  A 601 (-3.4A)
None
 1.00A 1ykiA-4dgkA:
undetectable
1ykiB-4dgkA:
undetectable		 1ykiA-4dgkA:
19.28
1ykiB-4dgkA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_B_NFZB2219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		4 / 8 THR A 358
PHE A 215
PHE A  50
GLY A 219
 EDO  A 601 (-3.4A)
None
None
None
 0.98A 1ykiA-4dgkA:
undetectable
1ykiB-4dgkA:
undetectable		 1ykiA-4dgkA:
19.28
1ykiB-4dgkA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_C_NFZC3219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		4 / 8 PHE A  50
GLY A 219
THR A 358
PHE A 215
 None
None
EDO  A 601 (-3.4A)
None
 0.99A 1ykiC-4dgkA:
undetectable
1ykiD-4dgkA:
undetectable		 1ykiC-4dgkA:
19.28
1ykiD-4dgkA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_D_NFZD4219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		4 / 8 THR A 358
PHE A 215
PHE A  50
GLY A 219
 EDO  A 601 (-3.4A)
None
None
None
 0.95A 1ykiC-4dgkA:
undetectable
1ykiD-4dgkA:
undetectable		 1ykiC-4dgkA:
19.28
1ykiD-4dgkA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZGF_A_TRUA300_1
(CARBONIC ANHYDRASE
II)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		5 / 12 HIS A 322
HIS A 353
HIS A 323
VAL A 213
THR A  55
 None
EDO  A 602 (-3.8A)
None
None
None
 1.27A 1zgfA-4dgkA:
undetectable		 1zgfA-4dgkA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		5 / 12 LEU A 230
ALA A  62
ILE A  63
ILE A 477
ALA A  15
 None
 1.07A 2bxcA-4dgkA:
1.7		 2bxcA-4dgkA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_G_BEZG2352_0
(D-AMINO-ACID OXIDASE)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		4 / 5 TYR A 136
TYR A 201
ILE A 204
GLY A 135
 None
 1.31A 2du8G-4dgkA:
10.7		 2du8G-4dgkA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_J_BEZJ3352_0
(D-AMINO-ACID OXIDASE)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		4 / 5 TYR A 136
TYR A 201
ILE A 204
GLY A 135
 None
 1.31A 2du8J-4dgkA:
10.4		 2du8J-4dgkA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		4 / 7 HIS A 323
ASP A  59
THR A  58
HIS A 353
 None
None
None
EDO  A 602 (-3.8A)
 1.46A 2dyrA-4dgkA:
undetectable
2dyrC-4dgkA:
undetectable		 2dyrA-4dgkA:
23.01
2dyrC-4dgkA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		4 / 6 HIS A 323
ASP A  59
THR A  58
HIS A 353
 None
None
None
EDO  A 602 (-3.8A)
 1.45A 2dysA-4dgkA:
undetectable
2dysC-4dgkA:
undetectable		 2dysA-4dgkA:
23.01
2dysC-4dgkA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_P_CHDP304_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		4 / 6 HIS A 323
ASP A  59
THR A  58
HIS A 353
 None
None
None
EDO  A 602 (-3.8A)
 1.44A 2dysN-4dgkA:
undetectable
2dysP-4dgkA:
undetectable		 2dysN-4dgkA:
23.01
2dysP-4dgkA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		4 / 7 HIS A 323
ASP A  59
THR A  58
HIS A 353
 None
None
None
EDO  A 602 (-3.8A)
 1.45A 2eijA-4dgkA:
undetectable
2eijC-4dgkA:
undetectable		 2eijA-4dgkA:
23.01
2eijC-4dgkA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		4 / 7 HIS A 323
ASP A  59
THR A  58
HIS A 353
 None
None
None
EDO  A 602 (-3.8A)
 1.48A 2eijN-4dgkA:
undetectable
2eijP-4dgkA:
undetectable		 2eijN-4dgkA:
23.01
2eijP-4dgkA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		4 / 7 HIS A 323
ASP A  59
THR A  58
HIS A 353
 None
None
None
EDO  A 602 (-3.8A)
 1.49A 2eikA-4dgkA:
undetectable
2eikC-4dgkA:
undetectable		 2eikA-4dgkA:
23.01
2eikC-4dgkA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		4 / 7 HIS A 323
ASP A  59
THR A  58
HIS A 353
 None
None
None
EDO  A 602 (-3.8A)
 1.49A 2eikN-4dgkA:
undetectable
2eikP-4dgkA:
undetectable		 2eikN-4dgkA:
23.01
2eikP-4dgkA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		4 / 7 HIS A 323
ASP A  59
THR A  58
HIS A 353
 None
None
None
EDO  A 602 (-3.8A)
 1.46A 2eilA-4dgkA:
undetectable
2eilC-4dgkA:
undetectable		 2eilA-4dgkA:
23.01
2eilC-4dgkA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		4 / 7 HIS A 323
ASP A  59
THR A  58
HIS A 353
 None
None
None
EDO  A 602 (-3.8A)
 1.48A 2eilN-4dgkA:
undetectable
2eilP-4dgkA:
undetectable		 2eilN-4dgkA:
23.01
2eilP-4dgkA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_A_CHDA525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		4 / 6 HIS A 323
ASP A  59
THR A  58
HIS A 353
 None
None
None
EDO  A 602 (-3.8A)
 1.46A 2eimA-4dgkA:
undetectable
2eimC-4dgkA:
undetectable		 2eimA-4dgkA:
23.01
2eimC-4dgkA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		4 / 6 HIS A 323
ASP A  59
THR A  58
HIS A 353
 None
None
None
EDO  A 602 (-3.8A)
 1.48A 2einA-4dgkA:
undetectable
2einC-4dgkA:
undetectable		 2einA-4dgkA:
23.01
2einC-4dgkA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GEH_A_NHYA300_1
(CARBONIC ANHYDRASE 2)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		5 / 8 HIS A 322
HIS A 353
HIS A 323
VAL A 213
THR A  55
 None
EDO  A 602 (-3.8A)
None
None
None
 1.27A 2gehA-4dgkA:
undetectable		 2gehA-4dgkA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GEH_A_NHYA300_1
(CARBONIC ANHYDRASE 2)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		5 / 8 HIS A 322
HIS A 353
VAL A  83
VAL A 213
THR A  55
 None
EDO  A 602 (-3.8A)
EDO  A 601 ( 3.9A)
None
None
 1.34A 2gehA-4dgkA:
undetectable		 2gehA-4dgkA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IT4_A_PPFA500_1
(CARBONIC ANHYDRASE 1)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		5 / 8 HIS A 322
HIS A 353
HIS A 323
VAL A 213
THR A  55
 None
EDO  A 602 (-3.8A)
None
None
None
 1.27A 2it4A-4dgkA:
undetectable		 2it4A-4dgkA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0G_A_LEUA1887_0
(AMINOACYL-TRNA
SYNTHETASE)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		4 / 8 ASP A  51
TYR A 371
TYR A 351
HIS A 322
 EDO  A 602 (-4.6A)
EDO  A 602 (-4.3A)
None
None
 1.14A 2v0gA-4dgkA:
undetectable		 2v0gA-4dgkA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAX_K_CSCK1385_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		5 / 12 LEU A 207
TYR A 121
ARG A 116
GLN A 123
VAL A 170
 None
 1.46A 2vaxK-4dgkA:
0.2		 2vaxK-4dgkA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VL2_B_BEZB1162_0
(PEROXIREDOXIN-5)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		4 / 7 PRO A 143
THR A  58
GLY A 212
LEU A 189
 None
 1.01A 2vl2B-4dgkA:
undetectable		 2vl2B-4dgkA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XNR_A_ACTA1001_0
(NUCLEAR
POLYADENYLATED
RNA-BINDING PROTEIN
3)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		3 / 3 SER A 165
ARG A 164
GLN A 161
 None
 0.66A 2xnrA-4dgkA:
undetectable		 2xnrA-4dgkA:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_A_CHDA1517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		4 / 7 HIS A 323
ASP A  59
THR A  58
HIS A 353
 None
None
None
EDO  A 602 (-3.8A)
 1.46A 2y69A-4dgkA:
undetectable
2y69C-4dgkA:
undetectable		 2y69A-4dgkA:
23.01
2y69C-4dgkA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		4 / 6 HIS A 323
ASP A  59
THR A  58
HIS A 353
 None
None
None
EDO  A 602 (-3.8A)
 1.46A 2zxwA-4dgkA:
undetectable
2zxwC-4dgkA:
undetectable		 2zxwA-4dgkA:
23.01
2zxwC-4dgkA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		4 / 6 HIS A 323
ASP A  59
THR A  58
HIS A 353
 None
None
None
EDO  A 602 (-3.8A)
 1.48A 2zxwN-4dgkA:
undetectable
2zxwP-4dgkA:
undetectable		 2zxwN-4dgkA:
23.01
2zxwP-4dgkA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		4 / 7 HIS A 323
ASP A  59
THR A  58
HIS A 353
 None
None
None
EDO  A 602 (-3.8A)
 1.47A 3abkA-4dgkA:
undetectable
3abkC-4dgkA:
undetectable		 3abkA-4dgkA:
23.01
3abkC-4dgkA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		4 / 7 HIS A 323
ASP A  59
THR A  58
HIS A 353
 None
None
None
EDO  A 602 (-3.8A)
 1.47A 3abkN-4dgkA:
undetectable
3abkP-4dgkA:
undetectable		 3abkN-4dgkA:
23.01
3abkP-4dgkA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		4 / 6 GLN A 103
PHE A 183
LEU A 179
PHE A 113
 None
 1.16A 3ablP-4dgkA:
undetectable
3ablW-4dgkA:
undetectable		 3ablP-4dgkA:
19.15
3ablW-4dgkA:
9.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		4 / 7 HIS A 323
ASP A  59
THR A  58
HIS A 353
 None
None
None
EDO  A 602 (-3.8A)
 1.46A 3abmN-4dgkA:
undetectable
3abmP-4dgkA:
undetectable		 3abmN-4dgkA:
23.01
3abmP-4dgkA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_A_CHDA525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		4 / 7 HIS A 323
ASP A  59
THR A  58
HIS A 353
 None
None
None
EDO  A 602 (-3.8A)
 1.48A 3ag2A-4dgkA:
undetectable
3ag2C-4dgkA:
undetectable		 3ag2A-4dgkA:
23.01
3ag2C-4dgkA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		4 / 7 HIS A 323
ASP A  59
THR A  58
HIS A 353
 None
None
None
EDO  A 602 (-3.8A)
 1.49A 3ag2N-4dgkA:
undetectable
3ag2P-4dgkA:
undetectable		 3ag2N-4dgkA:
23.01
3ag2P-4dgkA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		4 / 7 HIS A 323
ASP A  59
THR A  58
HIS A 353
 None
None
None
EDO  A 602 (-3.8A)
 1.48A 3ag3A-4dgkA:
undetectable
3ag3C-4dgkA:
undetectable		 3ag3A-4dgkA:
23.01
3ag3C-4dgkA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		4 / 7 HIS A 323
ASP A  59
THR A  58
HIS A 353
 None
None
None
EDO  A 602 (-3.8A)
 1.47A 3ag3N-4dgkA:
undetectable
3ag3P-4dgkA:
undetectable		 3ag3N-4dgkA:
23.01
3ag3P-4dgkA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		4 / 7 HIS A 323
ASP A  59
THR A  58
HIS A 353
 None
None
None
EDO  A 602 (-3.8A)
 1.49A 3ag4A-4dgkA:
undetectable
3ag4C-4dgkA:
undetectable		 3ag4A-4dgkA:
23.01
3ag4C-4dgkA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_A_PAUA248_0
(TYPE III
PANTOTHENATE KINASE)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		5 / 10 VAL A   6
GLY A  13
THR A 483
THR A   4
LEU A  20
 None
 1.26A 3bexA-4dgkA:
undetectable
3bexB-4dgkA:
undetectable		 3bexA-4dgkA:
18.70
3bexB-4dgkA:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_C_PAUC248_0
(TYPE III
PANTOTHENATE KINASE)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		5 / 11 VAL A   6
GLY A  13
THR A 483
THR A   4
LEU A  20
 None
 1.25A 3bexC-4dgkA:
undetectable
3bexD-4dgkA:
undetectable		 3bexC-4dgkA:
18.70
3bexD-4dgkA:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_F_PAUF248_0
(TYPE III
PANTOTHENATE KINASE)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		5 / 11 THR A   4
LEU A  20
VAL A   6
GLY A  13
THR A 483
 None
 1.27A 3bexE-4dgkA:
undetectable
3bexF-4dgkA:
undetectable		 3bexE-4dgkA:
18.70
3bexF-4dgkA:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_A_PAUA248_0
(TYPE III
PANTOTHENATE KINASE)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		5 / 11 VAL A   6
GLY A  13
THR A 483
THR A   4
LEU A  20
 None
 1.28A 3bf1A-4dgkA:
undetectable
3bf1B-4dgkA:
undetectable		 3bf1A-4dgkA:
18.70
3bf1B-4dgkA:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_C_PAUC248_0
(TYPE III
PANTOTHENATE KINASE)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		5 / 11 VAL A   6
GLY A  13
THR A 483
THR A   4
LEU A  20
 None
 1.27A 3bf1C-4dgkA:
undetectable
3bf1D-4dgkA:
undetectable		 3bf1C-4dgkA:
18.70
3bf1D-4dgkA:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_E_PAUE248_0
(TYPE III
PANTOTHENATE KINASE)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		5 / 11 VAL A   6
GLY A  13
THR A 483
THR A   4
LEU A  20
 None
 1.26A 3bf1E-4dgkA:
undetectable
3bf1F-4dgkA:
undetectable		 3bf1E-4dgkA:
18.70
3bf1F-4dgkA:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_F_PAUF248_0
(TYPE III
PANTOTHENATE KINASE)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		5 / 11 THR A   4
LEU A  20
VAL A   6
GLY A  13
THR A 483
 None
 1.26A 3bf1E-4dgkA:
undetectable
3bf1F-4dgkA:
undetectable		 3bf1E-4dgkA:
18.70
3bf1F-4dgkA:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BL1_A_BL1A300_1
(CARBONIC ANHYDRASE 2)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		5 / 12 HIS A 322
HIS A 353
HIS A 323
VAL A 213
THR A  55
 None
EDO  A 602 (-3.8A)
None
None
None
 1.31A 3bl1A-4dgkA:
undetectable		 3bl1A-4dgkA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZV_B_AZMB263_1
(CARBONIC ANHYDRASE
13)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		5 / 10 HIS A 322
HIS A 353
HIS A 323
VAL A 213
THR A  55
 None
EDO  A 602 (-3.8A)
None
None
None
 1.27A 3czvB-4dgkA:
undetectable		 3czvB-4dgkA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZV_B_AZMB263_1
(CARBONIC ANHYDRASE
13)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		5 / 10 HIS A 322
HIS A 353
VAL A  83
VAL A 213
THR A  55
 None
EDO  A 602 (-3.8A)
EDO  A 601 ( 3.9A)
None
None
 1.36A 3czvB-4dgkA:
undetectable		 3czvB-4dgkA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCW_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		5 / 10 HIS A 322
HIS A 353
HIS A 323
VAL A 213
THR A  55
 None
EDO  A 602 (-3.8A)
None
None
None
 1.32A 3dcwA-4dgkA:
undetectable		 3dcwA-4dgkA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD0_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		5 / 10 HIS A 322
HIS A 353
HIS A 323
VAL A 213
THR A  55
 None
EDO  A 602 (-3.8A)
None
None
None
 1.30A 3dd0A-4dgkA:
undetectable		 3dd0A-4dgkA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJ3_B_MTXB609_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		5 / 12 ALA A  17
LEU A 230
LYS A 229
ILE A  63
LEU A 223
 None
 1.09A 3hj3B-4dgkA:
undetectable		 3hj3B-4dgkA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS4_A_AZMA701_1
(CARBONIC ANHYDRASE 2)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		5 / 11 HIS A 322
HIS A 353
HIS A 323
VAL A 213
THR A  55
 None
EDO  A 602 (-3.8A)
None
None
None
 1.29A 3hs4A-4dgkA:
undetectable		 3hs4A-4dgkA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ML5_A_AZMA264_1
(CARBONIC ANHYDRASE 7)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		5 / 11 HIS A 322
HIS A 353
HIS A 323
VAL A 213
THR A  55
 None
EDO  A 602 (-3.8A)
None
None
None
 1.28A 3ml5A-4dgkA:
undetectable		 3ml5A-4dgkA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ML5_A_AZMA264_1
(CARBONIC ANHYDRASE 7)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		5 / 11 HIS A 322
HIS A 353
VAL A  83
VAL A 213
THR A  55
 None
EDO  A 602 (-3.8A)
EDO  A 601 ( 3.9A)
None
None
 1.35A 3ml5A-4dgkA:
undetectable		 3ml5A-4dgkA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V2J_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		5 / 11 HIS A 322
HIS A 353
HIS A 323
VAL A 213
THR A  55
 None
EDO  A 602 (-3.8A)
None
None
None
 1.30A 3v2jA-4dgkA:
undetectable		 3v2jA-4dgkA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V81_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		4 / 8 LEU A  20
VAL A 463
TYR A 461
LEU A 488
 None
 1.12A 3v81A-4dgkA:
undetectable		 3v81A-4dgkA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COQ_A_SANA300_1
(CARBONATE
DEHYDRATASE)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		5 / 10 HIS A 322
HIS A 353
HIS A 323
VAL A 213
THR A  55
 None
EDO  A 602 (-3.8A)
None
None
None
 1.31A 4coqA-4dgkA:
undetectable		 4coqA-4dgkA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COQ_A_SANA300_1
(CARBONATE
DEHYDRATASE)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		5 / 10 HIS A 322
HIS A 353
VAL A  83
VAL A 213
THR A  55
 None
EDO  A 602 (-3.8A)
EDO  A 601 ( 3.9A)
None
None
 1.36A 4coqA-4dgkA:
undetectable		 4coqA-4dgkA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COQ_B_SANB300_1
(CARBONATE
DEHYDRATASE)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		5 / 9 HIS A 322
HIS A 353
HIS A 323
VAL A 213
THR A  55
 None
EDO  A 602 (-3.8A)
None
None
None
 1.30A 4coqB-4dgkA:
undetectable		 4coqB-4dgkA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COQ_B_SANB300_1
(CARBONATE
DEHYDRATASE)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		5 / 9 HIS A 322
HIS A 353
VAL A  83
VAL A 213
THR A  55
 None
EDO  A 602 (-3.8A)
EDO  A 601 ( 3.9A)
None
None
 1.36A 4coqB-4dgkA:
undetectable		 4coqB-4dgkA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K0S_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		5 / 11 HIS A 322
HIS A 353
HIS A 323
VAL A 213
THR A  55
 None
EDO  A 602 (-3.8A)
None
None
None
 1.30A 4k0sA-4dgkA:
undetectable		 4k0sA-4dgkA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MI4_C_SPMC201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		4 / 7 TYR A 167
ASN A 114
GLU A 177
GLU A 175
 None
 1.29A 4mi4A-4dgkA:
undetectable
4mi4C-4dgkA:
undetectable		 4mi4A-4dgkA:
17.18
4mi4C-4dgkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_C_AZMC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		5 / 11 HIS A 322
HIS A 353
HIS A 323
VAL A 213
THR A  55
 None
EDO  A 602 (-3.8A)
None
None
None
 1.29A 4ygfC-4dgkA:
undetectable		 4ygfC-4dgkA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_C_AZMC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		5 / 11 HIS A 322
HIS A 353
VAL A  83
VAL A 213
THR A  55
 None
EDO  A 602 (-3.8A)
EDO  A 601 ( 3.9A)
None
None
 1.31A 4ygfC-4dgkA:
undetectable		 4ygfC-4dgkA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_D_AZMD303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		5 / 11 HIS A 322
HIS A 353
HIS A 323
VAL A 213
THR A  55
 None
EDO  A 602 (-3.8A)
None
None
None
 1.31A 4ygfD-4dgkA:
undetectable		 4ygfD-4dgkA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_D_AZMD303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		5 / 11 HIS A 322
HIS A 353
VAL A  83
VAL A 213
THR A  55
 None
EDO  A 602 (-3.8A)
EDO  A 601 ( 3.9A)
None
None
 1.32A 4ygfD-4dgkA:
undetectable		 4ygfD-4dgkA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_E_AZME303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		5 / 12 HIS A 322
HIS A 353
HIS A 323
VAL A 213
THR A  55
 None
EDO  A 602 (-3.8A)
None
None
None
 1.36A 4ygfE-4dgkA:
undetectable		 4ygfE-4dgkA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_E_AZME303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		5 / 12 HIS A 322
HIS A 353
VAL A  83
VAL A 213
THR A  55
 None
EDO  A 602 (-3.8A)
EDO  A 601 ( 3.9A)
None
None
 1.36A 4ygfE-4dgkA:
undetectable		 4ygfE-4dgkA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_F_AZMF303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		5 / 9 HIS A 322
HIS A 353
HIS A 323
VAL A 213
THR A  55
 None
EDO  A 602 (-3.8A)
None
None
None
 1.26A 4ygfF-4dgkA:
undetectable		 4ygfF-4dgkA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_F_AZMF303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		5 / 9 HIS A 322
HIS A 353
VAL A  83
VAL A 213
THR A  55
 None
EDO  A 602 (-3.8A)
EDO  A 601 ( 3.9A)
None
None
 1.35A 4ygfF-4dgkA:
undetectable		 4ygfF-4dgkA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_H_AZMH303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		5 / 9 HIS A 322
HIS A 353
HIS A 323
VAL A 213
THR A  55
 None
EDO  A 602 (-3.8A)
None
None
None
 1.35A 4ygfH-4dgkA:
undetectable		 4ygfH-4dgkA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_H_AZMH303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		5 / 9 HIS A 322
HIS A 353
VAL A  83
VAL A 213
THR A  55
 None
EDO  A 602 (-3.8A)
EDO  A 601 ( 3.9A)
None
None
 1.37A 4ygfH-4dgkA:
undetectable		 4ygfH-4dgkA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_A_MZMA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		5 / 12 HIS A 322
HIS A 353
HIS A 323
VAL A 213
THR A  55
 None
EDO  A 602 (-3.8A)
None
None
None
 1.31A 4yhaA-4dgkA:
undetectable		 4yhaA-4dgkA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_A_MZMA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		5 / 12 HIS A 322
HIS A 353
VAL A  83
VAL A 213
THR A  55
 None
EDO  A 602 (-3.8A)
EDO  A 601 ( 3.9A)
None
None
 1.34A 4yhaA-4dgkA:
undetectable		 4yhaA-4dgkA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_C_MZMC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		5 / 11 HIS A 322
HIS A 353
HIS A 323
VAL A 213
THR A  55
 None
EDO  A 602 (-3.8A)
None
None
None
 1.31A 4yhaC-4dgkA:
undetectable		 4yhaC-4dgkA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_C_MZMC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		5 / 11 HIS A 322
HIS A 353
VAL A  83
VAL A 213
THR A  55
 None
EDO  A 602 (-3.8A)
EDO  A 601 ( 3.9A)
None
None
 1.35A 4yhaC-4dgkA:
undetectable		 4yhaC-4dgkA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_G_MZMG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		5 / 12 HIS A 322
HIS A 353
HIS A 323
VAL A 213
THR A  55
 None
EDO  A 602 (-3.8A)
None
None
None
 1.26A 4yhaG-4dgkA:
undetectable		 4yhaG-4dgkA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_G_MZMG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		5 / 12 HIS A 322
HIS A 353
VAL A  83
VAL A 213
THR A  55
 None
EDO  A 602 (-3.8A)
EDO  A 601 ( 3.9A)
None
None
 1.31A 4yhaG-4dgkA:
undetectable		 4yhaG-4dgkA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		4 / 7 HIS A 323
ASP A  59
THR A  58
HIS A 353
 None
None
None
EDO  A 602 (-3.8A)
 1.48A 5b1aN-4dgkA:
undetectable
5b1aP-4dgkA:
undetectable		 5b1aN-4dgkA:
23.01
5b1aP-4dgkA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I8F_A_ML1A210_1
(PHENOLIC OXIDATIVE
COUPLING PROTEIN)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		5 / 12 PHE A 185
LEU A 151
TYR A 405
TYR A 400
GLY A 328
 None
None
EDO  A 604 (-4.9A)
None
None
 1.45A 5i8fA-4dgkA:
undetectable		 5i8fA-4dgkA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN8_A_AZMA701_1
(CARBONIC ANHYDRASE 4)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		5 / 10 HIS A 322
HIS A 353
HIS A 323
VAL A 213
THR A  55
 None
EDO  A 602 (-3.8A)
None
None
None
 1.32A 5jn8A-4dgkA:
undetectable		 5jn8A-4dgkA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN8_A_AZMA701_1
(CARBONIC ANHYDRASE 4)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		5 / 10 HIS A 322
HIS A 353
VAL A  83
VAL A 213
THR A  55
 None
EDO  A 602 (-3.8A)
EDO  A 601 ( 3.9A)
None
None
 1.40A 5jn8A-4dgkA:
undetectable		 5jn8A-4dgkA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		5 / 10 HIS A 322
HIS A 353
HIS A 323
VAL A 213
THR A  55
 None
EDO  A 602 (-3.8A)
None
None
None
 1.31A 5jn9A-4dgkA:
undetectable		 5jn9A-4dgkA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		5 / 10 HIS A 322
HIS A 353
VAL A  83
VAL A 213
THR A  55
 None
EDO  A 602 (-3.8A)
EDO  A 601 ( 3.9A)
None
None
 1.41A 5jn9A-4dgkA:
undetectable		 5jn9A-4dgkA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_B_EZLB302_1
(CARBONIC ANHYDRASE 4)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		5 / 10 HIS A 322
HIS A 353
HIS A 323
VAL A 213
THR A  55
 None
EDO  A 602 (-3.8A)
None
None
None
 1.31A 5jn9B-4dgkA:
undetectable		 5jn9B-4dgkA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_B_EZLB302_1
(CARBONIC ANHYDRASE 4)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		5 / 10 HIS A 322
HIS A 353
VAL A  83
VAL A 213
THR A  55
 None
EDO  A 602 (-3.8A)
EDO  A 601 ( 3.9A)
None
None
 1.36A 5jn9B-4dgkA:
undetectable		 5jn9B-4dgkA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_D_EZLD302_1
(CARBONIC ANHYDRASE 4)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		5 / 10 HIS A 322
HIS A 353
HIS A 323
VAL A 213
THR A  55
 None
EDO  A 602 (-3.8A)
None
None
None
 1.32A 5jn9D-4dgkA:
undetectable		 5jn9D-4dgkA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_D_EZLD302_1
(CARBONIC ANHYDRASE 4)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		5 / 10 HIS A 322
HIS A 353
VAL A  83
VAL A 213
THR A  55
 None
EDO  A 602 (-3.8A)
EDO  A 601 ( 3.9A)
None
None
 1.41A 5jn9D-4dgkA:
undetectable		 5jn9D-4dgkA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNA_B_TORB302_1
(CARBONIC ANHYDRASE 4)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		5 / 12 HIS A 322
HIS A 353
HIS A 323
VAL A 213
THR A  55
 None
EDO  A 602 (-3.8A)
None
None
None
 1.34A 5jnaB-4dgkA:
undetectable		 5jnaB-4dgkA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_B_6LHB302_0
(CARBONIC ANHYDRASE 4)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		5 / 10 HIS A 322
HIS A 353
HIS A 323
VAL A 213
THR A  55
 None
EDO  A 602 (-3.8A)
None
None
None
 1.30A 5jncB-4dgkA:
undetectable		 5jncB-4dgkA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_B_6LHB302_0
(CARBONIC ANHYDRASE 4)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		5 / 10 HIS A 322
HIS A 353
VAL A  83
VAL A 213
THR A  55
 None
EDO  A 602 (-3.8A)
EDO  A 601 ( 3.9A)
None
None
 1.37A 5jncB-4dgkA:
undetectable		 5jncB-4dgkA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KU6_A_MZMA301_1
(CARBONIC ANHYDRASE 4)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		5 / 10 HIS A 322
HIS A 353
HIS A 323
VAL A 213
THR A  55
 None
EDO  A 602 (-3.8A)
None
None
None
 1.32A 5ku6A-4dgkA:
undetectable		 5ku6A-4dgkA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KU6_A_MZMA301_1
(CARBONIC ANHYDRASE 4)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		5 / 10 HIS A 322
HIS A 353
VAL A  83
VAL A 213
THR A  55
 None
EDO  A 602 (-3.8A)
EDO  A 601 ( 3.9A)
None
None
 1.40A 5ku6A-4dgkA:
undetectable		 5ku6A-4dgkA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KU6_B_MZMB302_1
(CARBONIC ANHYDRASE 4)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		5 / 10 HIS A 322
HIS A 353
HIS A 323
VAL A 213
THR A  55
 None
EDO  A 602 (-3.8A)
None
None
None
 1.31A 5ku6B-4dgkA:
undetectable		 5ku6B-4dgkA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KU6_B_MZMB302_1
(CARBONIC ANHYDRASE 4)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		5 / 10 HIS A 322
HIS A 353
VAL A  83
VAL A 213
THR A  55
 None
EDO  A 602 (-3.8A)
EDO  A 601 ( 3.9A)
None
None
 1.38A 5ku6B-4dgkA:
undetectable		 5ku6B-4dgkA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_B_TESB502_1
(-)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		5 / 12 LEU A 259
LEU A  30
ILE A 254
PRO A   3
LEU A 266
 None
 1.08A 5og9B-4dgkA:
undetectable		 5og9B-4dgkA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_C_EZLC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		5 / 10 HIS A 322
HIS A 353
HIS A 323
VAL A 213
THR A  55
 None
EDO  A 602 (-3.8A)
None
None
None
 1.33A 5tt3C-4dgkA:
undetectable		 5tt3C-4dgkA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		5 / 8 HIS A 322
HIS A 353
HIS A 323
VAL A 213
THR A  55
 None
EDO  A 602 (-3.8A)
None
None
None
 1.38A 5tt3F-4dgkA:
undetectable		 5tt3F-4dgkA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		5 / 8 HIS A 322
HIS A 353
VAL A  83
VAL A 213
THR A  55
 None
EDO  A 602 (-3.8A)
EDO  A 601 ( 3.9A)
None
None
 1.35A 5tt3F-4dgkA:
undetectable		 5tt3F-4dgkA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_G_EZLG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		5 / 9 HIS A 322
HIS A 353
HIS A 323
VAL A 213
THR A  55
 None
EDO  A 602 (-3.8A)
None
None
None
 1.33A 5tt3G-4dgkA:
undetectable		 5tt3G-4dgkA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_G_EZLG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		5 / 9 HIS A 322
HIS A 353
VAL A  83
VAL A 213
THR A  55
 None
EDO  A 602 (-3.8A)
EDO  A 601 ( 3.9A)
None
None
 1.36A 5tt3G-4dgkA:
undetectable		 5tt3G-4dgkA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		4 / 6 HIS A 323
ASP A  59
THR A  58
HIS A 353
 None
None
None
EDO  A 602 (-3.8A)
 1.50A 5x19N-4dgkA:
undetectable
5x19P-4dgkA:
undetectable		 5x19N-4dgkA:
23.01
5x19P-4dgkA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		4 / 6 GLN A 103
PHE A 183
LEU A 179
PHE A 113
 None
 1.05A 5z84P-4dgkA:
undetectable
5z84W-4dgkA:
undetectable		 5z84P-4dgkA:
19.15
5z84W-4dgkA:
9.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		4 / 6 GLN A 103
PHE A 183
LEU A 179
PHE A 113
 None
 1.06A 5z85P-4dgkA:
undetectable
5z85W-4dgkA:
undetectable		 5z85P-4dgkA:
19.15
5z85W-4dgkA:
9.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		4 / 6 GLN A 103
PHE A 183
LEU A 179
PHE A 113
 None
 1.01A 5z86C-4dgkA:
undetectable
5z86J-4dgkA:
undetectable		 5z86C-4dgkA:
19.15
5z86J-4dgkA:
9.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		4 / 6 GLN A 103
PHE A 183
LEU A 179
PHE A 113
 None
 1.05A 5z86P-4dgkA:
undetectable
5z86W-4dgkA:
undetectable		 5z86P-4dgkA:
19.15
5z86W-4dgkA:
9.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		4 / 6 GLN A 103
PHE A 183
LEU A 179
PHE A 113
 None
 1.04A 5zcoP-4dgkA:
undetectable
5zcoW-4dgkA:
undetectable		 5zcoP-4dgkA:
19.15
5zcoW-4dgkA:
9.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		4 / 6 GLN A 103
PHE A 183
LEU A 179
PHE A 113
 None
 0.99A 5zcpC-4dgkA:
undetectable
5zcpJ-4dgkA:
undetectable		 5zcpC-4dgkA:
19.15
5zcpJ-4dgkA:
9.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		4 / 6 GLN A 103
PHE A 183
LEU A 179
PHE A 113
 None
 1.05A 5zcpP-4dgkA:
undetectable
5zcpW-4dgkA:
undetectable		 5zcpP-4dgkA:
19.15
5zcpW-4dgkA:
9.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		4 / 6 HIS A 323
ASP A  59
THR A  58
HIS A 353
 None
None
None
EDO  A 602 (-3.8A)
 1.46A 6nknA-4dgkA:
undetectable
6nknC-4dgkA:
undetectable		 6nknA-4dgkA:
23.01
6nknC-4dgkA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_P_CHDP302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4dgk PHYTOENE
DEHYDROGENASE
(Pantoea
ananatis) 		4 / 7 HIS A 323
ASP A  59
THR A  58
HIS A 353
 None
None
None
EDO  A 602 (-3.8A)
 1.50A 6nmpN-4dgkA:
undetectable
6nmpP-4dgkA:
undetectable		 6nmpN-4dgkA:
23.01
6nmpP-4dgkA:
19.15