SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4dgs'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LBG_A_ADNA402_1 (PROBABLE SUGAR KINASE PROTEIN)	4dgs	DEHYDROGENASE (Sinorhizobium meliloti)	5 / 10	SER A 165 GLU A 168 ILE A 151 VAL A 153 ALA A 108	None	1.07A	4lbgA-4dgsA: 4.1	4lbgA-4dgsA: 29.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PEV_A_ADNA501_2 (MEMBRANE LIPOPROTEIN FAMILY PROTEIN)	4dgs	DEHYDROGENASE (Sinorhizobium meliloti)	3 / 3	PRO A 69 LEU A 68 HIS A 31	None	0.65A	4pevA-4dgsA: 5.4	4pevA-4dgsA: 21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UC3_A_486A801_2 (GLUCOCORTICOID RECEPTOR)	4dgs	DEHYDROGENASE (Sinorhizobium meliloti)	4 / 5	LEU A 11 LEU A 33 MET A 16 TYR A 28	None	1.31A	5uc3A-4dgsA: undetectable	5uc3A-4dgsA: 12.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6F6I_A_8PRA509_1 (ENVELOPE GLYCOPROTEIN,GP,GP1 ENVELOPE GLYCOPROTEIN)	4dgs	DEHYDROGENASE (Sinorhizobium meliloti)	5 / 12	VAL A 231 ALA A 257 GLY A 256 THR A 278 LEU A 222	None	0.67A	6f6iA-4dgsA: undetectable 6f6iB-4dgsA: undetectable	6f6iA-4dgsA: 13.70 6f6iB-4dgsA: 13.00

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["4LBG_A_ADNA402_1","PROBABLE SUGAR KINASE PROTEIN","4dgs","DEHYDROGENASE","Sinorhizobium meliloti",5,"SER A 165;GLU A 168;ILE A 151;VAL A 153;ALA A 108","None","1.07A","4lbgA-4dgsA:4.1","4lbgA-4dgsA:29.72"],["4PEV_A_ADNA501_2","MEMBRANE LIPOPROTEIN FAMILY PROTEIN","4dgs","DEHYDROGENASE","Sinorhizobium meliloti",3,"PRO A  69;LEU A  68;HIS A  31","None","0.65A","4pevA-4dgsA:5.4","4pevA-4dgsA:21.96"],["5UC3_A_486A801_2","GLUCOCORTICOID RECEPTOR","4dgs","DEHYDROGENASE","Sinorhizobium meliloti",4,"LEU A  11;LEU A  33;MET A  16;TYR A  28","None","1.31A","5uc3A-4dgsA:undetectable","5uc3A-4dgsA:12.87"],["6F6I_A_8PRA509_1","ENVELOPE GLYCOPROTEIN,GP,GP1;ENVELOPE GLYCOPROTEIN","4dgs","DEHYDROGENASE","Sinorhizobium meliloti",5,"VAL A 231;ALA A 257;GLY A 256;THR A 278;LEU A 222","None","0.67A","6f6iA-4dgsA:undetectable;6f6iB-4dgsA:undetectable","6f6iA-4dgsA:13.70;6f6iB-4dgsA:13.00"]]