SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4dgu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CET_A_CLQA1001_0
(PROTEIN (L-LACTATE
DEHYDROGENASE))		 4dgu PUTATIVE CELL
ADHESION PROTEIN
(Bacteroides
thetaiotaomicron) 		5 / 9 GLY A 130
ILE A  38
ALA A 101
PHE A  78
ILE A  66
 None
 1.18A 1cetA-4dguA:
undetectable		 1cetA-4dguA:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_C_ZMRC3478_1
(NEURAMINIDASE)		 4dgu PUTATIVE CELL
ADHESION PROTEIN
(Bacteroides
thetaiotaomicron) 		4 / 8 SER A  37
ASP A  39
ASN A 140
GLN A 139
 None
 1.01A 2cmlC-4dguA:
undetectable		 2cmlC-4dguA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IB1_A_IMNA701_1
(LACTOTRANSFERRIN)		 4dgu PUTATIVE CELL
ADHESION PROTEIN
(Bacteroides
thetaiotaomicron) 		4 / 4 PRO A 211
THR A 149
GLY A 130
THR A 131
 None
 1.06A 3ib1A-4dguA:
undetectable		 3ib1A-4dguA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDT_B_VORB506_1
(CHOLESTEROL
24-HYDROXYLASE)		 4dgu PUTATIVE CELL
ADHESION PROTEIN
(Bacteroides
thetaiotaomicron) 		5 / 11 LEU A 143
VAL A 141
SER A 142
ILE A  66
ALA A  70
 None
 1.14A 3mdtB-4dguA:
undetectable		 3mdtB-4dguA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AN2_A_EUIA1382_2
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)		 4dgu PUTATIVE CELL
ADHESION PROTEIN
(Bacteroides
thetaiotaomicron) 		4 / 4 ASN A 208
SER A 171
LEU A 172
THR A 206
 None
 1.47A 4an2A-4dguA:
undetectable		 4an2A-4dguA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ECK_B_FOLB703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 4dgu PUTATIVE CELL
ADHESION PROTEIN
(Bacteroides
thetaiotaomicron) 		5 / 12 VAL A 198
SER A 247
LEU A 250
VAL A 168
THR A 206
 None
 1.17A 4eckB-4dguA:
undetectable		 4eckB-4dguA:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EIL_B_FOLB703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 4dgu PUTATIVE CELL
ADHESION PROTEIN
(Bacteroides
thetaiotaomicron) 		5 / 10 VAL A 198
SER A 247
LEU A 250
VAL A 168
THR A 206
 None
 1.17A 4eilB-4dguA:
undetectable		 4eilB-4dguA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7Z_A_BHAA201_0
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 4dgu PUTATIVE CELL
ADHESION PROTEIN
(Bacteroides
thetaiotaomicron) 		4 / 6 LEU A 240
VAL A 209
LEU A 172
VAL A 152
 None
 0.93A 5x7zA-4dguA:
undetectable		 5x7zA-4dguA:
17.00