SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4dhx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2C12_C_SPMC1434_1 (NITROALKANE OXIDASE)	4dhx	80 KDA MCM3-ASSOCIATED PROTEIN ENHANCER OF YELLOW 2 TRANSCRIPTION FACTOR HOMOLOG (Homo sapiens)	5 / 12	LEU B 20 VAL A1173 LEU B 88 SER A1168 LEU A1171	None	1.18A	2c12C-4dhxB: undetectable	2c12C-4dhxB: 12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2C12_F_SPMF1433_1 (NITROALKANE OXIDASE)	4dhx	80 KDA MCM3-ASSOCIATED PROTEIN ENHANCER OF YELLOW 2 TRANSCRIPTION FACTOR HOMOLOG (Homo sapiens)	5 / 11	LEU B 20 VAL A1173 LEU B 88 SER A1168 LEU A1171	None	1.23A	2c12F-4dhxB: undetectable	2c12F-4dhxB: 12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ZQT_A_30ZA1920_1 (ANDROGEN RECEPTOR)	4dhx	ENHANCER OF YELLOW 2 TRANSCRIPTION FACTOR HOMOLOG (Homo sapiens)	4 / 6	PRO B 73 GLY B 75 LEU B 46 GLU B 70	None	0.97A	3zqtA-4dhxB: undetectable	3zqtA-4dhxB: 18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4BQF_B_QPSB951_1 (ALPHA-GLUCAN PHOSPHORYLASE 2, CYTOSOLIC)	4dhx	80 KDA MCM3-ASSOCIATED PROTEIN ENHANCER OF YELLOW 2 TRANSCRIPTION FACTOR HOMOLOG (Homo sapiens)	4 / 8	ARG B 34 TRP B 42 GLU A1186 LYS B 47	None	1.10A	4bqfB-4dhxB: undetectable	4bqfB-4dhxB: 7.52

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2C12_C_SPMC1434_1","NITROALKANE OXIDASE","4dhx","80 KDA MCM3-ASSOCIATED PROTEIN;ENHANCER OF YELLOW 2 TRANSCRIPTION FACTOR HOMOLOG","Homo sapiens",5,"LEU B  20;VAL A1173;LEU B  88;SER A1168;LEU A1171","None","1.18A","2c12C-4dhxB:undetectable","2c12C-4dhxB:12.53"],["2C12_F_SPMF1433_1","NITROALKANE OXIDASE","4dhx","80 KDA MCM3-ASSOCIATED PROTEIN;ENHANCER OF YELLOW 2 TRANSCRIPTION FACTOR HOMOLOG","Homo sapiens",5,"LEU B  20;VAL A1173;LEU B  88;SER A1168;LEU A1171","None","1.23A","2c12F-4dhxB:undetectable","2c12F-4dhxB:12.53"],["3ZQT_A_30ZA1920_1","ANDROGEN RECEPTOR","4dhx","ENHANCER OF YELLOW 2 TRANSCRIPTION FACTOR HOMOLOG","Homo sapiens",4,"PRO B  73;GLY B  75;LEU B  46;GLU B  70","None","0.97A","3zqtA-4dhxB:undetectable","3zqtA-4dhxB:18.44"],["4BQF_B_QPSB951_1","ALPHA-GLUCAN PHOSPHORYLASE 2, CYTOSOLIC","4dhx","80 KDA MCM3-ASSOCIATED PROTEIN;ENHANCER OF YELLOW 2 TRANSCRIPTION FACTOR HOMOLOG","Homo sapiens",4,"ARG B  34;TRP B  42;GLU A1186;LYS B  47","None","1.10A","4bqfB-4dhxB:undetectable","4bqfB-4dhxB:7.52"]]