SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4dib'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DSS_G_CCSG149_0
(D-GLYCERALDEHYDE-3-P
HOSPHATE-DEHYDROGENA
SE)		 4dib GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(Bacillus
anthracis) 		4 / 7 ASN A 314
TYR A 318
ASN A 154
TYR A 312
 None
 0.97A 1dssG-4dibA:
45.1		 1dssG-4dibA:
46.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DSS_G_CCSG149_0
(D-GLYCERALDEHYDE-3-P
HOSPHATE-DEHYDROGENA
SE)		 4dib GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(Bacillus
anthracis) 		7 / 7 SER A 150
THR A 152
ASN A 154
CYH A 155
TYR A 312
ASN A 314
TYR A 318
 None
 0.25A 1dssG-4dibA:
45.1		 1dssG-4dibA:
46.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DSS_R_CCSR149_0
(D-GLYCERALDEHYDE-3-P
HOSPHATE-DEHYDROGENA
SE)		 4dib GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(Bacillus
anthracis) 		4 / 8 ASN A 314
TYR A 318
ASN A 154
TYR A 312
 None
 0.96A 1dssR-4dibA:
45.0		 1dssR-4dibA:
46.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DSS_R_CCSR149_0
(D-GLYCERALDEHYDE-3-P
HOSPHATE-DEHYDROGENA
SE)		 4dib GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(Bacillus
anthracis) 		6 / 8 SER A 150
ASN A 154
CYH A 155
HIS A 178
TYR A 312
TYR A 318
 None
 0.72A 1dssR-4dibA:
45.0		 1dssR-4dibA:
46.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DSS_R_CCSR149_0
(D-GLYCERALDEHYDE-3-P
HOSPHATE-DEHYDROGENA
SE)		 4dib GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(Bacillus
anthracis) 		7 / 8 SER A 150
THR A 152
ASN A 154
CYH A 155
TYR A 312
ASN A 314
TYR A 318
 None
 0.25A 1dssR-4dibA:
45.0		 1dssR-4dibA:
46.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_2
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 4dib GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(Bacillus
anthracis) 		4 / 4 THR A 152
LEU A 156
VAL A 159
LEU A 163
 None
 0.51A 1fbmD-4dibA:
undetectable		 1fbmD-4dibA:
7.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JU6_A_LYAA317_1
(THYMIDYLATE SYNTHASE)		 4dib GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(Bacillus
anthracis) 		5 / 11 PHE A  17
ILE A   6
GLY A  10
PHE A   9
ALA A 120
 None
 1.32A 1ju6A-4dibA:
undetectable		 1ju6A-4dibA:
24.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L2I_B_CCSB417_0
(ESTROGEN RECEPTOR)		 4dib GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(Bacillus
anthracis) 		4 / 6 PHE A 167
GLN A 166
LYS A 161
VAL A 159
 None
None
SO4  A 401 ( 4.7A)
None
 1.36A 1l2iB-4dibA:
undetectable		 1l2iB-4dibA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_4
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 4dib GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(Bacillus
anthracis) 		4 / 4 THR A 152
LEU A 156
VAL A 159
LEU A 163
 None
 0.80A 1mz9D-4dibA:
undetectable		 1mz9D-4dibA:
8.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_A_BEZA1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 4dib GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(Bacillus
anthracis) 		4 / 7 VAL A  92
LEU A 118
PHE A  99
THR A  96
 None
 1.03A 2f78A-4dibA:
undetectable		 2f78A-4dibA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_B_BEZB1004_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 4dib GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(Bacillus
anthracis) 		4 / 7 VAL A  92
LEU A 118
PHE A  99
THR A  96
 None
 1.09A 2f78B-4dibA:
undetectable		 2f78B-4dibA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNH_A_9CRA502_1
(CYTOCHROME P450 2C8)		 4dib GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(Bacillus
anthracis) 		5 / 12 ILE A 292
ILE A 293
ASN A 154
ASN A 287
VAL A 308
 None
 0.93A 2nnhA-4dibA:
undetectable		 2nnhA-4dibA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_NCAA493_0
(CHORISMATE SYNTHASE)		 4dib GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(Bacillus
anthracis) 		5 / 11 ALA A  95
THR A 119
ILE A 117
ILE A   6
VAL A 322
 None
 1.16A 2qhfA-4dibA:
undetectable		 2qhfA-4dibA:
21.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DMT_C_CCSC166_0
(GLYCERALDEHYDE-3-PHO
SPHATE
DEHYDROGENASE,
GLYCOSOMAL)		 4dib GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(Bacillus
anthracis) 		4 / 8 ASN A 314
TYR A 318
ASN A 154
TYR A 312
 None
 0.99A 3dmtC-4dibA:
43.6		 3dmtC-4dibA:
45.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DMT_C_CCSC166_0
(GLYCERALDEHYDE-3-PHO
SPHATE
DEHYDROGENASE,
GLYCOSOMAL)		 4dib GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(Bacillus
anthracis) 		7 / 8 SER A 150
THR A 152
ASN A 154
CYH A 155
HIS A 178
TYR A 312
TYR A 318
 None
 0.72A 3dmtC-4dibA:
43.6		 3dmtC-4dibA:
45.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DMT_C_CCSC166_0
(GLYCERALDEHYDE-3-PHO
SPHATE
DEHYDROGENASE,
GLYCOSOMAL)		 4dib GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(Bacillus
anthracis) 		7 / 8 SER A 150
THR A 152
ASN A 154
CYH A 155
TYR A 312
ASN A 314
TYR A 318
 None
 0.23A 3dmtC-4dibA:
43.6		 3dmtC-4dibA:
45.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP5_B_KANB2002_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 4dib GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(Bacillus
anthracis) 		3 / 3 ALA A 230
ARG A 196
LYS A 194
 None
 1.07A 3kp5B-4dibA:
undetectable		 3kp5B-4dibA:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AGA_A_ACTA1131_0
(LYSOZYME C)		 4dib GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(Bacillus
anthracis) 		3 / 3 ASN A 237
ASP A 313
ASN A 314
 None
 0.72A 4agaA-4dibA:
undetectable		 4agaA-4dibA:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IB4_A_ERMA2001_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 4dib GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(Bacillus
anthracis) 		5 / 12 VAL A 322
VAL A 145
ALA A  20
PHE A  26
VAL A 329
 None
 1.22A 4ib4A-4dibA:
undetectable		 4ib4A-4dibA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NC3_A_ERMA1202_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 4dib GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(Bacillus
anthracis) 		5 / 12 VAL A 272
SER A 290
ALA A 310
LEU A 222
VAL A 130
 None
 1.35A 4nc3A-4dibA:
undetectable		 4nc3A-4dibA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UUU_B_SAMB1548_0
(CYSTATHIONINE
BETA-SYNTHASE)		 4dib GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(Bacillus
anthracis) 		5 / 11 SER A 150
LEU A 156
PRO A 158
VAL A 130
THR A 128
 None
 1.14A 4uuuB-4dibA:
undetectable		 4uuuB-4dibA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERS_A_ACTA803_0
(GEPHYRIN)		 4dib GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(Bacillus
anthracis) 		3 / 3 THR A 153
ALA A 149
ASN A 154
 None
 0.56A 5ersA-4dibA:
2.2		 5ersA-4dibA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUE_A_VIVA302_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 4dib GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(Bacillus
anthracis) 		5 / 12 ILE A  12
VAL A 322
ILE A  71
VAL A  66
ILE A  44
 None
 0.91A 5mueA-4dibA:
undetectable		 5mueA-4dibA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUG_A_VIVA301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 4dib GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(Bacillus
anthracis) 		5 / 12 ILE A  12
VAL A 322
ILE A  71
VAL A  66
ILE A  44
 None
 0.93A 5mugA-4dibA:
undetectable		 5mugA-4dibA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WM2_A_ACTA605_0
(SALICYLATE-AMP
LIGASE)		 4dib GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(Bacillus
anthracis) 		3 / 3 THR A 208
THR A 207
ARG A 196
 None
 0.98A 5wm2A-4dibA:
2.1		 5wm2A-4dibA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X66_D_MTXD402_1
(THYMIDYLATE SYNTHASE)		 4dib GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(Bacillus
anthracis) 		5 / 10 PHE A  17
ILE A   6
GLY A  10
PHE A   9
ALA A 120
 None
 1.44A 5x66D-4dibA:
undetectable		 5x66D-4dibA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_C_SAMC902_0
(MRNA CAPPING ENZYME
P5)		 4dib GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(Bacillus
anthracis) 		5 / 12 GLY A 295
PRO A 278
ASP A 294
PHE A 260
THR A 298
 None
 1.36A 5x6yC-4dibA:
undetectable		 5x6yC-4dibA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA605_0
(ALPHA-AMYLASE)		 4dib GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(Bacillus
anthracis) 		4 / 8 GLY A  13
ILE A  12
ASP A  47
HIS A  50
 None
 0.93A 6ag0A-4dibA:
undetectable		 6ag0A-4dibA:
12.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC605_0
(ALPHA-AMYLASE)		 4dib GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(Bacillus
anthracis) 		4 / 8 GLY A  13
ILE A  12
ASP A  47
HIS A  50
 None
 0.87A 6ag0C-4dibA:
undetectable		 6ag0C-4dibA:
12.42