SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4dj3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_B_FUAB703_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4dj3 PERIOD CIRCADIAN
PROTEIN HOMOLOG 3
(Mus
musculus) 		3 / 3 VAL A 288
ALA A 287
HIS A 370
 None
 0.58A 1q23C-4dj3A:
undetectable		 1q23C-4dj3A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_G_FUAG708_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4dj3 PERIOD CIRCADIAN
PROTEIN HOMOLOG 3
(Mus
musculus) 		3 / 3 VAL A 288
ALA A 287
HIS A 370
 None
 0.66A 1q23H-4dj3A:
undetectable		 1q23H-4dj3A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_I_FUAI707_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4dj3 PERIOD CIRCADIAN
PROTEIN HOMOLOG 3
(Mus
musculus) 		3 / 3 VAL A 288
ALA A 287
HIS A 370
 None
 0.63A 1q23G-4dj3A:
undetectable		 1q23G-4dj3A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_K_FUAK712_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4dj3 PERIOD CIRCADIAN
PROTEIN HOMOLOG 3
(Mus
musculus) 		3 / 3 VAL A 288
ALA A 287
HIS A 370
 None
 0.58A 1q23L-4dj3A:
undetectable		 1q23L-4dj3A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_L_FUAL710_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4dj3 PERIOD CIRCADIAN
PROTEIN HOMOLOG 3
(Mus
musculus) 		3 / 3 VAL A 288
ALA A 287
HIS A 370
 None
 0.66A 1q23J-4dj3A:
undetectable		 1q23J-4dj3A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q0I_A_BEZA990_0
(QUINOLONE SIGNAL
RESPONSE PROTEIN)		 4dj3 PERIOD CIRCADIAN
PROTEIN HOMOLOG 3
(Mus
musculus) 		4 / 8 ASP A 311
LEU A 307
SER A 350
HIS A 370
 None
 0.98A 2q0iA-4dj3A:
undetectable		 2q0iA-4dj3A:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LB3_B_4CHB192_0
(DEHALOPEROXIDASE A)		 4dj3 PERIOD CIRCADIAN
PROTEIN HOMOLOG 3
(Mus
musculus) 		4 / 6 PHE A 280
PHE A 338
THR A 272
VAL A 283
 None
 1.23A 3lb3B-4dj3A:
undetectable		 3lb3B-4dj3A:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFN_A_ROCA401_2
(HIV-1 PROTEASE)		 4dj3 PERIOD CIRCADIAN
PROTEIN HOMOLOG 3
(Mus
musculus) 		4 / 7 ARG A 373
GLY A 257
ILE A 263
VAL A 346
 None
 0.83A 3ufnB-4dj3A:
undetectable		 3ufnB-4dj3A:
13.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VN2_A_TLSA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 4dj3 PERIOD CIRCADIAN
PROTEIN HOMOLOG 3
(Mus
musculus) 		5 / 12 CYH A 278
SER A 302
ILE A 396
LEU A 399
LEU A 406
 None
 1.38A 3vn2A-4dj3A:
undetectable		 3vn2A-4dj3A:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_B_2FAB401_2
(ADENOSINE KINASE)		 4dj3 PERIOD CIRCADIAN
PROTEIN HOMOLOG 3
(Mus
musculus) 		4 / 5 LEU A 161
ILE A 212
ALA A 134
PHE A 132
 None
 0.99A 4dc3B-4dj3A:
undetectable		 4dc3B-4dj3A:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_C_ADNC501_2
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 4dj3 PERIOD CIRCADIAN
PROTEIN HOMOLOG 3
(Mus
musculus) 		3 / 3 PRO A 225
VAL A 251
HIS A 124
 None
 0.83A 4pevC-4dj3A:
undetectable		 4pevC-4dj3A:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGF_B_ADNB502_1
(ADENOSYLHOMOCYSTEINA
SE)		 4dj3 PERIOD CIRCADIAN
PROTEIN HOMOLOG 3
(Mus
musculus) 		5 / 12 ASP A 284
GLU A 285
LEU A 291
LEU A 290
GLY A 257
 None
 1.14A 4pgfB-4dj3A:
undetectable		 4pgfB-4dj3A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJD_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 4dj3 PERIOD CIRCADIAN
PROTEIN HOMOLOG 3
(Mus
musculus) 		5 / 9 LEU A 307
LEU A 291
ILE A 367
THR A 272
ILE A 303
 None
 1.47A 5ljdA-4dj3A:
undetectable		 5ljdA-4dj3A:
17.97