SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4djh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DBB_H_STRH229_1
(IGG1-KAPPA DB3 FAB
(HEAVY CHAIN)
IGG1-KAPPA DB3 FAB
(LIGHT CHAIN))		 4djh KAPPA-TYPE OPIOID
RECEPTOR, LYSOZYME
(Escherichia
virus
T4;
Homo
sapiens) 		4 / 8 GLY A  76
ASN A  77
GLY A  73
VAL A 279
 None
 0.89A 1dbbH-4djhA:
undetectable
1dbbL-4djhA:
undetectable		 1dbbH-4djhA:
16.98
1dbbL-4djhA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N4F_A_ASRA140_0
(LYSOZYME C)		 4djh KAPPA-TYPE OPIOID
RECEPTOR, LYSOZYME
(Homo
sapiens;
Escherichia
virus
T4) 		3 / 3 ASN A  95
ALA A 175
ASN A 179
 None
 0.80A 1n4fA-4djhA:
2.5		 1n4fA-4djhA:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_F_NCAF369_0
(ADP-RIBOSYL CYCLASE)		 4djh KAPPA-TYPE OPIOID
RECEPTOR, LYSOZYME
(Homo
sapiens;
Escherichia
virus
T4) 		3 / 3 GLU A1005
ASN A1002
TRP A1158
 None
 1.29A 1r15F-4djhA:
undetectable		 1r15F-4djhA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACL_A_REAA502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4djh KAPPA-TYPE OPIOID
RECEPTOR, LYSOZYME
(Escherichia
virus
T4;
Homo
sapiens) 		5 / 12 ALA A1129
PHE A1153
LEU A1133
ALA A1130
ILE A1078
 None
 0.97A 2aclA-4djhA:
undetectable
2aclE-4djhA:
undetectable		 2aclA-4djhA:
18.58
2aclE-4djhA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E1Q_A_SALA2006_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 4djh KAPPA-TYPE OPIOID
RECEPTOR, LYSOZYME
(Escherichia
virus
T4;
Homo
sapiens) 		4 / 6 PHE A1153
VAL A1087
LEU A1118
ALA A1129
 None
 1.07A 2e1qA-4djhA:
undetectable		 2e1qA-4djhA:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JST_A_HLTA101_1
(FOUR-ALPHA-HELIX
BUNDLE)		 4djh KAPPA-TYPE OPIOID
RECEPTOR, LYSOZYME
(Escherichia
virus
T4;
Homo
sapiens) 		4 / 5 TRP A1158
ALA A1098
LEU A 258
ALA A1097
 None
 1.16A 2jstA-4djhA:
undetectable
2jstB-4djhA:
undetectable		 2jstA-4djhA:
7.48
2jstB-4djhA:
7.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FAL_C_REAC501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4djh KAPPA-TYPE OPIOID
RECEPTOR, LYSOZYME
(Escherichia
virus
T4;
Homo
sapiens) 		5 / 10 ALA A1129
PHE A1153
LEU A1133
ALA A1130
ILE A1078
 None
 1.05A 3falC-4djhA:
undetectable		 3falC-4djhA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FC6_A_REAA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4djh KAPPA-TYPE OPIOID
RECEPTOR, LYSOZYME
(Escherichia
virus
T4;
Homo
sapiens) 		5 / 11 ALA A1129
PHE A1153
LEU A1133
ALA A1130
ILE A1078
 None
 1.00A 3fc6A-4djhA:
undetectable		 3fc6A-4djhA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_A_RITA401_2
(SECRETED ASPARTIC
PROTEASE)		 4djh KAPPA-TYPE OPIOID
RECEPTOR, LYSOZYME
(Escherichia
virus
T4;
Homo
sapiens) 		4 / 6 TYR A 330
VAL A  80
THR A  94
THR A  92
 None
 1.15A 3tneA-4djhA:
undetectable		 3tneA-4djhA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKL_B_SUZB201_1
(TRANSTHYRETIN)		 4djh KAPPA-TYPE OPIOID
RECEPTOR, LYSOZYME
(Escherichia
virus
T4;
Homo
sapiens) 		4 / 8 SER A 324
LEU A 333
ALA A 331
LEU A 329
 None
 0.93A 4iklA-4djhA:
undetectable
4iklB-4djhA:
undetectable		 4iklA-4djhA:
14.58
4iklB-4djhA:
14.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_D_SAMD301_1
(UNCHARACTERIZED
PROTEIN)		 4djh KAPPA-TYPE OPIOID
RECEPTOR, LYSOZYME
(Homo
sapiens;
Escherichia
virus
T4) 		3 / 3 ARG A1148
GLU A1011
TYR A1161
 None
 0.87A 4r29D-4djhA:
undetectable		 4r29D-4djhA:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5Q_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 4djh KAPPA-TYPE OPIOID
RECEPTOR, LYSOZYME
(Homo
sapiens;
Escherichia
virus
T4) 		4 / 6 ASP A 155
ALA A 166
THR A  94
THR A  92
 None
 1.44A 4w5qA-4djhA:
undetectable		 4w5qA-4djhA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5R_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 4djh KAPPA-TYPE OPIOID
RECEPTOR, LYSOZYME
(Homo
sapiens;
Escherichia
virus
T4) 		4 / 6 ASP A 155
ALA A 166
THR A  94
THR A  92
 None
 1.46A 4w5rA-4djhA:
undetectable		 4w5rA-4djhA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4F_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 4djh KAPPA-TYPE OPIOID
RECEPTOR, LYSOZYME
(Homo
sapiens;
Escherichia
virus
T4) 		4 / 6 ASP A 155
ALA A 166
THR A  94
THR A  92
 None
 1.46A 4z4fA-4djhA:
undetectable		 4z4fA-4djhA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4G_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 4djh KAPPA-TYPE OPIOID
RECEPTOR, LYSOZYME
(Homo
sapiens;
Escherichia
virus
T4) 		4 / 5 ASP A 155
ALA A 166
THR A  94
THR A  92
 None
 1.48A 4z4gA-4djhA:
undetectable		 4z4gA-4djhA:
19.09