SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4dji'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G5Y_B_9CRB501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4dji PROBABLE
GLUTAMATE/GAMMA-AMIN
OBUTYRATE ANTIPORTER
(Escherichia
coli) 		5 / 12 ILE A 101
ALA A 352
LEU A 135
LEU A 107
ILE A 104
 None
 1.23A 1g5yB-4djiA:
2.5		 1g5yB-4djiA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX8_A_RTLA135_0
(CELLULAR
RETINOL-BINDING
PROTEIN I, HOLO)		 4dji PROBABLE
GLUTAMATE/GAMMA-AMIN
OBUTYRATE ANTIPORTER
(Escherichia
coli) 		5 / 12 PHE A  35
TYR A  32
ALA A 209
ARG A 497
PHE A  19
 None
 1.16A 1mx8A-4djiA:
undetectable		 1mx8A-4djiA:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_I_BEZI518_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 4dji PROBABLE
GLUTAMATE/GAMMA-AMIN
OBUTYRATE ANTIPORTER
(Escherichia
coli) 		4 / 7 GLY A 112
PRO A  33
ASN A 363
ASN A 124
 None
 0.90A 1oniG-4djiA:
undetectable
1oniI-4djiA:
0.1		 1oniG-4djiA:
14.17
1oniI-4djiA:
14.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_C_CTXC3_2
(CES1 PROTEIN)		 4dji PROBABLE
GLUTAMATE/GAMMA-AMIN
OBUTYRATE ANTIPORTER
(Escherichia
coli) 		4 / 4 LEU A 138
PRO A 127
ILE A 104
LEU A 107
 None
 1.15A 1ya4C-4djiA:
undetectable		 1ya4C-4djiA:
24.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CPP_A_CAMA422_0
(CYTOCHROME P450-CAM)		 4dji PROBABLE
GLUTAMATE/GAMMA-AMIN
OBUTYRATE ANTIPORTER
(Escherichia
coli) 		4 / 7 PHE A  18
TYR A 234
THR A  22
VAL A 217
 None
 0.98A 2cppA-4djiA:
undetectable		 2cppA-4djiA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F6D_A_ACRA996_1
(GLUCOAMYLASE GLU1)		 4dji PROBABLE
GLUTAMATE/GAMMA-AMIN
OBUTYRATE ANTIPORTER
(Escherichia
coli) 		4 / 7 ASN A 507
ASP A 508
THR A 475
GLY A 476
 None
 0.88A 2f6dA-4djiA:
undetectable		 2f6dA-4djiA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QL8_B_BEZB143_0
(PUTATIVE REDOX
PROTEIN)		 4dji PROBABLE
GLUTAMATE/GAMMA-AMIN
OBUTYRATE ANTIPORTER
(Escherichia
coli) 		4 / 6 TYR A 234
THR A  66
ALA A  65
PRO A 230
 None
 1.43A 2ql8A-4djiA:
undetectable
2ql8B-4djiA:
undetectable		 2ql8A-4djiA:
14.29
2ql8B-4djiA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6R_B_CTCB1385_0
(TETX2 PROTEIN)		 4dji PROBABLE
GLUTAMATE/GAMMA-AMIN
OBUTYRATE ANTIPORTER
(Escherichia
coli) 		4 / 8 GLN A  98
PHE A 103
GLY A 102
PRO A 312
 None
 0.93A 2y6rB-4djiA:
undetectable		 2y6rB-4djiA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGO_A_PCFA1213_1
(WNT INHIBITORY
FACTOR 1)		 4dji PROBABLE
GLUTAMATE/GAMMA-AMIN
OBUTYRATE ANTIPORTER
(Escherichia
coli) 		4 / 6 LEU A 449
ILE A 369
PRO A 433
VAL A  57
 None
 1.03A 2ygoA-4djiA:
undetectable		 2ygoA-4djiA:
14.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z0Y_A_SAMA300_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0657)		 4dji PROBABLE
GLUTAMATE/GAMMA-AMIN
OBUTYRATE ANTIPORTER
(Escherichia
coli) 		5 / 9 GLY A 252
LEU A 278
ILE A 170
LEU A 174
ALA A 175
 None
 0.94A 2z0yA-4djiA:
undetectable		 2z0yA-4djiA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZM8_A_ACAA511_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 4dji PROBABLE
GLUTAMATE/GAMMA-AMIN
OBUTYRATE ANTIPORTER
(Escherichia
coli) 		4 / 8 ALA A 168
TYR A  32
ILE A 164
TYR A  30
 None
 1.01A 2zm8A-4djiA:
undetectable		 2zm8A-4djiA:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APV_B_TP0B190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 4dji PROBABLE
GLUTAMATE/GAMMA-AMIN
OBUTYRATE ANTIPORTER
(Escherichia
coli) 		5 / 12 PHE A  35
TYR A  32
GLU A 304
ALA A 245
SER A 213
 None
 1.35A 3apvB-4djiA:
undetectable		 3apvB-4djiA:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APW_A_DP0A190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 4dji PROBABLE
GLUTAMATE/GAMMA-AMIN
OBUTYRATE ANTIPORTER
(Escherichia
coli) 		5 / 12 PHE A  35
TYR A  32
GLU A 304
SER A 249
SER A 213
 None
 1.36A 3apwA-4djiA:
undetectable		 3apwA-4djiA:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_A_SAMA300_0
(PUTATIVE RRNA
METHYLASE)		 4dji PROBABLE
GLUTAMATE/GAMMA-AMIN
OBUTYRATE ANTIPORTER
(Escherichia
coli) 		5 / 12 THR A  37
GLY A 262
ASN A 263
ILE A 256
GLY A 253
 None
 1.17A 3eeyA-4djiA:
undetectable		 3eeyA-4djiA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_B_SAMB300_0
(PUTATIVE RRNA
METHYLASE)		 4dji PROBABLE
GLUTAMATE/GAMMA-AMIN
OBUTYRATE ANTIPORTER
(Escherichia
coli) 		5 / 12 THR A  37
GLY A 262
ASN A 263
ILE A 256
GLY A 253
 None
 1.17A 3eeyB-4djiA:
undetectable		 3eeyB-4djiA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_C_SAMC300_0
(PUTATIVE RRNA
METHYLASE)		 4dji PROBABLE
GLUTAMATE/GAMMA-AMIN
OBUTYRATE ANTIPORTER
(Escherichia
coli) 		5 / 12 THR A  37
GLY A 262
ASN A 263
ILE A 256
GLY A 253
 None
 1.17A 3eeyC-4djiA:
undetectable		 3eeyC-4djiA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_D_SAMD300_0
(PUTATIVE RRNA
METHYLASE)		 4dji PROBABLE
GLUTAMATE/GAMMA-AMIN
OBUTYRATE ANTIPORTER
(Escherichia
coli) 		5 / 12 THR A  37
GLY A 262
ASN A 263
ILE A 256
GLY A 253
 None
 1.18A 3eeyD-4djiA:
undetectable		 3eeyD-4djiA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_E_SAME300_0
(PUTATIVE RRNA
METHYLASE)		 4dji PROBABLE
GLUTAMATE/GAMMA-AMIN
OBUTYRATE ANTIPORTER
(Escherichia
coli) 		5 / 12 THR A  37
GLY A 262
ASN A 263
ILE A 256
GLY A 253
 None
 1.18A 3eeyE-4djiA:
undetectable		 3eeyE-4djiA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_H_SAMH300_0
(PUTATIVE RRNA
METHYLASE)		 4dji PROBABLE
GLUTAMATE/GAMMA-AMIN
OBUTYRATE ANTIPORTER
(Escherichia
coli) 		5 / 12 THR A  37
GLY A 262
ASN A 263
ILE A 256
GLY A 253
 None
 1.16A 3eeyH-4djiA:
undetectable		 3eeyH-4djiA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_I_SAMI300_0
(PUTATIVE RRNA
METHYLASE)		 4dji PROBABLE
GLUTAMATE/GAMMA-AMIN
OBUTYRATE ANTIPORTER
(Escherichia
coli) 		5 / 12 THR A  37
GLY A 262
ASN A 263
ILE A 256
GLY A 253
 None
 1.17A 3eeyI-4djiA:
undetectable		 3eeyI-4djiA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_J_SAMJ300_0
(PUTATIVE RRNA
METHYLASE)		 4dji PROBABLE
GLUTAMATE/GAMMA-AMIN
OBUTYRATE ANTIPORTER
(Escherichia
coli) 		5 / 12 THR A  37
GLY A 262
ASN A 263
ILE A 256
GLY A 253
 None
 1.17A 3eeyJ-4djiA:
undetectable		 3eeyJ-4djiA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 4dji PROBABLE
GLUTAMATE/GAMMA-AMIN
OBUTYRATE ANTIPORTER
(Escherichia
coli) 		4 / 7 TYR A 389
TYR A 234
VAL A 224
LEU A 385
 None
 0.80A 3elzA-4djiA:
undetectable		 3elzA-4djiA:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDR_B_GJZB506_1
(CHOLESTEROL
24-HYDROXYLASE)		 4dji PROBABLE
GLUTAMATE/GAMMA-AMIN
OBUTYRATE ANTIPORTER
(Escherichia
coli) 		4 / 6 ILE A 355
ALA A 352
ALA A 134
THR A 131
 None
 0.97A 3mdrB-4djiA:
undetectable		 3mdrB-4djiA:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Z_C_9PLC501_1
(CYTOCHROME P450 2E1)		 4dji PROBABLE
GLUTAMATE/GAMMA-AMIN
OBUTYRATE ANTIPORTER
(Escherichia
coli) 		4 / 5 PHE A 103
ALA A 306
THR A 144
LEU A 138
 None
 1.17A 3t3zC-4djiA:
undetectable		 3t3zC-4djiA:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_C_HCYC1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 4dji PROBABLE
GLUTAMATE/GAMMA-AMIN
OBUTYRATE ANTIPORTER
(Escherichia
coli) 		5 / 12 VAL A 110
GLN A 345
THR A 349
PHE A 103
ILE A 305
 None
 1.29A 4c49C-4djiA:
undetectable		 4c49C-4djiA:
24.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DU2_A_LDPA501_1
(CYTOCHROME P450 BM3
VARIANT B7)		 4dji PROBABLE
GLUTAMATE/GAMMA-AMIN
OBUTYRATE ANTIPORTER
(Escherichia
coli) 		4 / 7 ALA A 370
ALA A 352
LEU A 356
THR A 357
 None
 0.83A 4du2A-4djiA:
undetectable		 4du2A-4djiA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DU2_B_LDPB501_1
(CYTOCHROME P450 BM3
VARIANT B7)		 4dji PROBABLE
GLUTAMATE/GAMMA-AMIN
OBUTYRATE ANTIPORTER
(Escherichia
coli) 		4 / 7 ALA A 370
ALA A 352
LEU A 356
THR A 357
 None
 0.88A 4du2B-4djiA:
1.0		 4du2B-4djiA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FJP_A_NPSA711_1
(LACTOTRANSFERRIN)		 4dji PROBABLE
GLUTAMATE/GAMMA-AMIN
OBUTYRATE ANTIPORTER
(Escherichia
coli) 		4 / 6 GLY A 336
PRO A 338
TYR A 317
GLY A 315
 None
 0.91A 4fjpA-4djiA:
undetectable		 4fjpA-4djiA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_B_MXMB606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4dji PROBABLE
GLUTAMATE/GAMMA-AMIN
OBUTYRATE ANTIPORTER
(Escherichia
coli) 		5 / 12 ILE A 305
VAL A 110
ALA A 134
LEU A 138
LEU A 141
 None
 0.96A 4m11B-4djiA:
0.9		 4m11B-4djiA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNV_D_QI9D602_0
(CYTOCHROME P450 2D6)		 4dji PROBABLE
GLUTAMATE/GAMMA-AMIN
OBUTYRATE ANTIPORTER
(Escherichia
coli) 		4 / 7 PHE A 210
GLU A  31
SER A 249
VAL A 206
 None
 1.06A 4wnvD-4djiA:
undetectable		 4wnvD-4djiA:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNW_B_RTZB602_2
(CYTOCHROME P450 2D6)		 4dji PROBABLE
GLUTAMATE/GAMMA-AMIN
OBUTYRATE ANTIPORTER
(Escherichia
coli) 		3 / 3 GLU A  31
ILE A  99
ALA A 370
 None
 0.66A 4wnwB-4djiA:
0.5		 4wnwB-4djiA:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZC_E_ACTE406_0
(PROTON-GATED ION
CHANNEL)		 4dji PROBABLE
GLUTAMATE/GAMMA-AMIN
OBUTYRATE ANTIPORTER
(Escherichia
coli) 		4 / 5 ILE A 390
ARG A 401
TYR A 389
GLU A  63
 None
 1.23A 4zzcE-4djiA:
undetectable		 4zzcE-4djiA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_C_CVIC301_1
(REGULATORY PROTEIN
TETR)		 4dji PROBABLE
GLUTAMATE/GAMMA-AMIN
OBUTYRATE ANTIPORTER
(Escherichia
coli) 		4 / 7 GLN A 345
GLY A 102
ILE A 305
TYR A  30
 None
 1.14A 5vlmC-4djiA:
1.6		 5vlmC-4djiA:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WYQ_B_SAMB301_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 4dji PROBABLE
GLUTAMATE/GAMMA-AMIN
OBUTYRATE ANTIPORTER
(Escherichia
coli) 		6 / 12 LEU A 297
GLY A 300
ILE A 293
LEU A 166
GLY A 163
PRO A 167
 None
 1.46A 5wyqB-4djiA:
undetectable		 5wyqB-4djiA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7P_A_9SCA601_0
(SERUM ALBUMIN)		 4dji PROBABLE
GLUTAMATE/GAMMA-AMIN
OBUTYRATE ANTIPORTER
(Escherichia
coli) 		6 / 12 ILE A 256
PHE A 210
LYS A 200
VAL A 201
LEU A 432
LEU A 267
 None
 1.48A 6a7pA-4djiA:
undetectable		 6a7pA-4djiA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_S_PCFS603_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 8
CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL)		 4dji PROBABLE
GLUTAMATE/GAMMA-AMIN
OBUTYRATE ANTIPORTER
(Escherichia
coli) 		4 / 7 GLN A 273
GLY A 270
VAL A  29
SER A 294
 None
 1.06A 6hu9S-4djiA:
undetectable
6hu9q-4djiA:
undetectable		 6hu9S-4djiA:
10.69
6hu9q-4djiA:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_A_DCFA401_1
(ADENOSINE DEAMINASE)		 4dji PROBABLE
GLUTAMATE/GAMMA-AMIN
OBUTYRATE ANTIPORTER
(Escherichia
coli) 		4 / 4 HIS A 502
LEU A 341
TYR A  96
GLY A 311
 None
 1.22A 6n91A-4djiA:
undetectable		 6n91A-4djiA:
11.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QXS_B_FOZB403_0
(THYMIDYLATE SYNTHASE)		 4dji PROBABLE
GLUTAMATE/GAMMA-AMIN
OBUTYRATE ANTIPORTER
(Escherichia
coli) 		5 / 12 LEU A 107
ILE A 305
TRP A 308
LEU A 494
GLY A 300
 None
 0.96A 6qxsB-4djiA:
undetectable		 6qxsB-4djiA:
21.76