SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4djn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_D_DCFD1853_1
(ADENOSINE DEAMINASE)		 4djn RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
SUBUNIT M2 B
(Homo
sapiens) 		5 / 12 HIS A 134
PHE A 198
GLY A 229
HIS A 231
ASP A 100
 None
 1.28A 1a4lD-4djnA:
undetectable		 1a4lD-4djnA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_D_DCFD1853_1
(ADENOSINE DEAMINASE)		 4djn RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
SUBUNIT M2 B
(Homo
sapiens) 		5 / 12 HIS A 134
PHE A 198
PHE A 202
GLY A 229
HIS A 231
 None
 1.34A 1a4lD-4djnA:
undetectable		 1a4lD-4djnA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RNR_A_DAHA208_1
(RIBONUCLEOTIDE
REDUCTASE R1 PROTEIN)		 4djn RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
SUBUNIT M2 B
(Homo
sapiens) 		7 / 11 ASP A 100
GLU A 131
HIS A 134
GLU A 194
PHE A 202
ILE A 224
GLU A 228
 None
 0.58A 1rnrA-4djnA:
31.4		 1rnrA-4djnA:
24.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RNR_A_DAHA208_1
(RIBONUCLEOTIDE
REDUCTASE R1 PROTEIN)		 4djn RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
SUBUNIT M2 B
(Homo
sapiens) 		6 / 11 ASP A 100
HIS A 134
SER A 201
PHE A 202
ILE A 224
GLU A 228
 None
 0.95A 1rnrA-4djnA:
31.4		 1rnrA-4djnA:
24.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RNR_B_DAHB208_1
(RIBONUCLEOTIDE
REDUCTASE R1 PROTEIN)		 4djn RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
SUBUNIT M2 B
(Homo
sapiens) 		7 / 12 ASP A 100
GLU A 131
HIS A 134
GLU A 194
PHE A 202
ILE A 224
GLU A 228
 None
 0.49A 1rnrB-4djnA:
31.4		 1rnrB-4djnA:
24.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RNR_B_DAHB208_1
(RIBONUCLEOTIDE
REDUCTASE R1 PROTEIN)		 4djn RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
SUBUNIT M2 B
(Homo
sapiens) 		7 / 12 ASP A 100
GLU A 131
HIS A 134
TYR A 138
GLU A 194
ILE A 224
GLU A 228
 None
 0.58A 1rnrB-4djnA:
31.4		 1rnrB-4djnA:
24.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_IMNA2001_1
(SERUM ALBUMIN)		 4djn RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
SUBUNIT M2 B
(Homo
sapiens) 		5 / 10 ALA A 192
PHE A 190
TRP A 175
ALA A 172
LEU A 173
 None
 1.11A 2bxqA-4djnA:
undetectable		 2bxqA-4djnA:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_C_9PLC1_1
(CYTOCHROME P450 2A13)		 4djn RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
SUBUNIT M2 B
(Homo
sapiens) 		4 / 7 PHE A  96
PHE A 202
ALA A 203
LEU A 266
 None
 1.10A 3t3sC-4djnA:
undetectable		 3t3sC-4djnA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VN2_A_TLSA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 4djn RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
SUBUNIT M2 B
(Homo
sapiens) 		5 / 12 PHE A 206
SER A 220
HIS A 134
TYR A 138
LEU A  93
 None
 1.24A 3vn2A-4djnA:
2.2		 3vn2A-4djnA:
23.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R82_A_ACTA205_0
(OXIDOREDUCTASE)		 4djn RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
SUBUNIT M2 B
(Homo
sapiens) 		4 / 5 GLY A 184
ARG A 186
GLU A 114
PHE A 111
 None
 1.06A 4r82A-4djnA:
undetectable
4r82B-4djnA:
undetectable		 4r82A-4djnA:
18.71
4r82B-4djnA:
18.71