SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4dk0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H4J_A_NCAA1002_0
(NAD-DEPENDENT
DEACETYLASE)		 4dk0 PUTATIVE MACA
(Aggregatibacter
actinomycetemcom
itans) 		4 / 5 ALA A 293
ILE A 221
ASN A 294
ILE A 296
 None
 1.06A 2h4jA-4dk0A:
undetectable		 2h4jA-4dk0A:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KUH_A_HLTA150_1
(CALMODULIN)		 4dk0 PUTATIVE MACA
(Aggregatibacter
actinomycetemcom
itans) 		4 / 6 LEU A 304
LEU A 216
MET A 219
GLU A  53
 None
 1.19A 2kuhA-4dk0A:
undetectable		 2kuhA-4dk0A:
13.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P16_A_GG2A298_2
(COAGULATION FACTOR X
(EC 3.4.21.6)
(STUART FACTOR)
(STUART-PROWER
FACTOR))		 4dk0 PUTATIVE MACA
(Aggregatibacter
actinomycetemcom
itans) 		3 / 3 ARG A 114
GLU A 155
GLN A 110
 None
 0.79A 2p16A-4dk0A:
undetectable		 2p16A-4dk0A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1478_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 4dk0 PUTATIVE MACA
(Aggregatibacter
actinomycetemcom
itans) 		4 / 6 SER A  90
ASP A  89
ILE A  94
THR A  69
 None
 1.00A 4acbC-4dk0A:
3.5		 4acbC-4dk0A:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LV9_B_20JB602_1
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 4dk0 PUTATIVE MACA
(Aggregatibacter
actinomycetemcom
itans) 		4 / 7 VAL A 201
ILE A 210
ILE A 182
ALA A  86
 None
 0.89A 4lv9B-4dk0A:
undetectable		 4lv9B-4dk0A:
20.43