SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4dkm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_A_ROCA101_2
(PROTEASE)		 4dkm AMPHIOXUS GREEN
FLUORESCENT PROTEIN,
GFPC1A
(Branchiostoma
floridae) 		3 / 3 ARG A 166
VAL A  54
THR A 197
 None
None
CR2  A  60 ( 4.7A)
 0.81A 3ndtA-4dkmA:
undetectable		 3ndtA-4dkmA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SJ0_X_DXCX75_0
(CYTOCHROME C7)		 4dkm AMPHIOXUS GREEN
FLUORESCENT PROTEIN,
GFPC1A
(Branchiostoma
floridae) 		4 / 7 ILE A  57
LYS A  43
PHE A  20
GLY A  13
 CR2  A  60 ( 3.6A)
None
None
None
 1.00A 3sj0X-4dkmA:
undetectable		 3sj0X-4dkmA:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A3U_B_ACTB1358_0
(NADH:FLAVIN
OXIDOREDUCTASE/NADH
OXIDASE)		 4dkm AMPHIOXUS GREEN
FLUORESCENT PROTEIN,
GFPC1A
(Branchiostoma
floridae) 		4 / 7 ILE A  90
ARG A  88
GLY A 100
VAL A 117
 None
CR2  A  60 ( 2.8A)
None
None
 0.99A 4a3uB-4dkmA:
undetectable		 4a3uB-4dkmA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA608_0
(ALPHA-AMYLASE)		 4dkm AMPHIOXUS GREEN
FLUORESCENT PROTEIN,
GFPC1A
(Branchiostoma
floridae) 		4 / 6 PHE A 115
GLY A 113
GLN A  63
TYR A 106
 CR2  A  60 ( 4.7A)
None
CR2  A  60 ( 4.7A)
None
 1.15A 6ag0A-4dkmA:
undetectable		 6ag0A-4dkmA:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC606_0
(ALPHA-AMYLASE)		 4dkm AMPHIOXUS GREEN
FLUORESCENT PROTEIN,
GFPC1A
(Branchiostoma
floridae) 		4 / 6 PHE A 115
GLY A 113
GLN A  63
TYR A 106
 CR2  A  60 ( 4.7A)
None
CR2  A  60 ( 4.7A)
None
 1.13A 6ag0C-4dkmA:
undetectable		 6ag0C-4dkmA:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DEB_B_MTXB303_1
(BIFUNCTIONAL PROTEIN
FOLD)		 4dkm AMPHIOXUS GREEN
FLUORESCENT PROTEIN,
GFPC1A
(Branchiostoma
floridae) 		4 / 5 TYR A  64
GLN A 212
GLY A  81
ILE A 111
 None
 1.47A 6debB-4dkmA:
undetectable		 6debB-4dkmA:
15.87