SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4dks'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4dks PROBABLE INTEGRASE
(Sulfolobus
spindle-shaped
virus
1) 		4 / 6 LEU A 188
GLN A 189
LEU A 206
PHE A 283
 None
 1.01A 3ag1C-4dksA:
undetectable
3ag1J-4dksA:
undetectable		 3ag1C-4dksA:
21.29
3ag1J-4dksA:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		 4dks PROBABLE INTEGRASE
(Sulfolobus
spindle-shaped
virus
1) 		4 / 6 LEU A 206
PHE A 280
ILE A 178
PHE A 283
 None
 1.26A 4y4dA-4dksA:
undetectable		 4y4dA-4dksA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DQY_A_BEZA401_0
(THIOREDOXIN)		 4dks PROBABLE INTEGRASE
(Sulfolobus
spindle-shaped
virus
1) 		4 / 8 ILE A 297
LYS A 322
VAL A 293
GLU A 323
 None
 1.16A 5dqyA-4dksA:
undetectable		 5dqyA-4dksA:
22.09