SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4dmm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_B_HLTB4002_1
(SERUM ALBUMIN)		 4dmm 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Synechococcus
elongatus) 		4 / 4 ARG A 212
ALA A 192
ALA A 216
GLU A 218
 None
 1.08A 1e7bB-4dmmA:
undetectable		 1e7bB-4dmmA:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_1
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 4dmm 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Synechococcus
elongatus) 		4 / 4 ILE A 208
LEU A 246
VAL A 146
ALA A 163
 None
 0.97A 1mz9A-4dmmA:
undetectable		 1mz9A-4dmmA:
10.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_3
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 4dmm 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Synechococcus
elongatus) 		4 / 5 ILE A 208
LEU A 246
VAL A 146
ALA A 163
 None
 0.95A 1mz9C-4dmmA:
undetectable		 1mz9C-4dmmA:
10.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_F_SC2F1291_1
(FICOLIN-2)		 4dmm 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Synechococcus
elongatus) 		4 / 6 LEU A 114
SER A 112
ASP A 109
ASP A 108
 None
 1.17A 2j2pE-4dmmA:
undetectable
2j2pF-4dmmA:
undetectable		 2j2pE-4dmmA:
19.49
2j2pF-4dmmA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYR_B_SVRB401_4
(NAD-DEPENDENT
DEACETYLASE
SIRTUIN-5)		 4dmm 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Synechococcus
elongatus) 		4 / 5 ALA A  16
ALA A  29
ALA A  33
VAL A  89
 None
 0.94A 2nyrB-4dmmA:
5.1		 2nyrB-4dmmA:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_C_SALC1302_1
(LYSR-TYPE REGULATORY
PROTEIN)		 4dmm 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Synechococcus
elongatus) 		5 / 12 ILE A 191
GLY A 214
TYR A 213
GLY A 244
ILE A 208
 None
 1.26A 2y7kC-4dmmA:
undetectable		 2y7kC-4dmmA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7P_A_SALA1000_1
(LYSR-TYPE REGULATORY
PROTEIN)		 4dmm 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Synechococcus
elongatus) 		5 / 10 ILE A 191
GLY A 214
TYR A 213
GLY A 244
ILE A 208
 None
 1.31A 2y7pA-4dmmA:
undetectable		 2y7pA-4dmmA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7W_A_SALA1300_1
(LYSR-TYPE REGULATORY
PROTEIN)		 4dmm 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Synechococcus
elongatus) 		5 / 9 ILE A 191
GLY A 214
TYR A 213
GLY A 244
ILE A 208
 None
 1.32A 2y7wA-4dmmA:
undetectable		 2y7wA-4dmmA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_D_SAMD603_0
(HYPOTHETICAL PROTEIN)		 4dmm 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Synechococcus
elongatus) 		5 / 12 ILE A  20
GLY A  15
ALA A  23
ALA A  40
ASP A  66
 None
SO4  A 301 (-3.6A)
None
SO4  A 301 (-3.4A)
None
 1.04A 2yvlD-4dmmA:
7.2		 2yvlD-4dmmA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCP_B_CHDB1_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4dmm 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Synechococcus
elongatus) 		5 / 10 MET A 195
ARG A 212
PRO A 188
SER A 145
GLY A 244
 None
 1.41A 3hcpB-4dmmA:
3.5		 3hcpB-4dmmA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJD_A_C2FA314_0
(UNCHARACTERIZED
PROTEIN)		 4dmm 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Synechococcus
elongatus) 		5 / 12 THR A  14
VAL A 165
GLY A 164
LEU A 116
ILE A  96
 None
 1.03A 3ijdA-4dmmA:
undetectable		 3ijdA-4dmmA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQ6_B_ADNB401_2
(ADENOSINE KINASE,
PUTATIVE)		 4dmm 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Synechococcus
elongatus) 		4 / 5 LEU A 123
GLY A 120
PHE A  77
ASN A 142
 None
 1.31A 3uq6B-4dmmA:
7.0		 3uq6B-4dmmA:
28.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HFP_D_15UD402_1
(PROTHROMBIN)		 4dmm 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Synechococcus
elongatus) 		5 / 12 LEU A  87
ILE A 140
ALA A  25
ALA A  36
VAL A  35
 None
 1.12A 4hfpD-4dmmA:
undetectable		 4hfpD-4dmmA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHZ_D_READ602_1
(ALDEHYDE
DEHYDROGENASE FAMILY
1 MEMBER A3)		 4dmm 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Synechococcus
elongatus) 		5 / 12 ILE A  24
GLU A  27
ARG A 224
ASN A  92
LEU A 226
 None
 1.45A 5fhzD-4dmmA:
5.4		 5fhzD-4dmmA:
19.70