SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4dn9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RK3_A_VDXA500_1 (VITAMIN D3 RECEPTOR)	4dn9	ANTIBIOTIC BIOSYNTHESIS MONOOXYGENASE (Chloroflexus aurantiacus)	5 / 12	LEU A 65 VAL A 68 SER A 67 HIS A 59 LEU A 4	None	1.47A	1rk3A-4dn9A: undetectable	1rk3A-4dn9A: 19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3VT3_A_VDXA500_1 (VITAMIN D3 RECEPTOR)	4dn9	ANTIBIOTIC BIOSYNTHESIS MONOOXYGENASE (Chloroflexus aurantiacus)	5 / 12	LEU A 65 VAL A 68 SER A 67 HIS A 59 LEU A 4	None	1.44A	3vt3A-4dn9A: undetectable	3vt3A-4dn9A: 18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3VT7_A_VDXA500_1 (VITAMIN D3 RECEPTOR)	4dn9	ANTIBIOTIC BIOSYNTHESIS MONOOXYGENASE (Chloroflexus aurantiacus)	5 / 12	LEU A 65 VAL A 68 SER A 67 HIS A 59 LEU A 4	None	1.47A	3vt7A-4dn9A: undetectable	3vt7A-4dn9A: 18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3WDM_A_ADNA901_1 (4-PHOSPHOPANTOATE--B ETA-ALANINE LIGASE)	4dn9	ANTIBIOTIC BIOSYNTHESIS MONOOXYGENASE (Chloroflexus aurantiacus)	5 / 9	ALA A 71 GLY A 75 LEU A 22 LEU A 78 ILE A 47	None DIO A 200 ( 4.9A) None None None	1.46A	3wdmA-4dn9A: undetectable	3wdmA-4dn9A: 18.60

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1RK3_A_VDXA500_1","VITAMIN D3 RECEPTOR","4dn9","ANTIBIOTIC BIOSYNTHESIS MONOOXYGENASE","Chloroflexus aurantiacus",5,"LEU A  65;VAL A  68;SER A  67;HIS A  59;LEU A   4","None","1.47A","1rk3A-4dn9A:undetectable","1rk3A-4dn9A:19.37"],["3VT3_A_VDXA500_1","VITAMIN D3 RECEPTOR","4dn9","ANTIBIOTIC BIOSYNTHESIS MONOOXYGENASE","Chloroflexus aurantiacus",5,"LEU A  65;VAL A  68;SER A  67;HIS A  59;LEU A   4","None","1.44A","3vt3A-4dn9A:undetectable","3vt3A-4dn9A:18.45"],["3VT7_A_VDXA500_1","VITAMIN D3 RECEPTOR","4dn9","ANTIBIOTIC BIOSYNTHESIS MONOOXYGENASE","Chloroflexus aurantiacus",5,"LEU A  65;VAL A  68;SER A  67;HIS A  59;LEU A   4","None","1.47A","3vt7A-4dn9A:undetectable","3vt7A-4dn9A:18.45"],["3WDM_A_ADNA901_1","4-PHOSPHOPANTOATE--BETA-ALANINE LIGASE","4dn9","ANTIBIOTIC BIOSYNTHESIS MONOOXYGENASE","Chloroflexus aurantiacus",5,"ALA A  71;GLY A  75;LEU A  22;LEU A  78;ILE A  47","None;DIO A 200 ( 4.9A);None;None;None","1.46A","3wdmA-4dn9A:undetectable","3wdmA-4dn9A:18.60"]]