SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4dne'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2O5Y_H_STRH249_1 (CHIMERIC ANTIBODY FAB 1E9-DB3)	4dne	STREPTAVIDIN (Streptomyces avidinii)	4 / 7	TRP A 75 GLY A 94 THR A 106 TRP A 108	None None None DTB A 201 (-3.3A)	1.26A	2o5yH-4dneA: undetectable 2o5yL-4dneA: undetectable	2o5yH-4dneA: 23.87 2o5yL-4dneA: 24.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2UZ2_A_ACTA1123_0 (XENAVIDIN)	4dne	STREPTAVIDIN (Streptomyces avidinii)	6 / 7	ASN A 23 LEU A 25 SER A 27 TYR A 43 THR A 45 TRP A 92	DTB A 201 (-3.4A) DTB A 201 ( 4.7A) DTB A 201 (-2.6A) DTB A 201 (-4.7A) DTB A 201 (-3.7A) DTB A 201 ( 4.5A)	0.35A	2uz2A-4dneA: 16.6	2uz2A-4dneA: 28.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SI7_A_ACTA4_0 (CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR)	4dne	STREPTAVIDIN (Streptomyces avidinii)	4 / 4	LEU A 73 GLY A 74 GLY A 94 THR A 106	None	0.95A	3si7A-4dneA: undetectable	3si7A-4dneA: 18.87