SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4dnh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_A_SWFA502_1
(CYTOCHROME P450 2C9)		 4dnh UNCHARACTERIZED
PROTEIN
(Sinorhizobium
meliloti) 		5 / 12 ALA A  42
PHE A  68
LEU A  77
LEU A 115
PHE A  39
 None
 1.23A 1og5A-4dnhA:
undetectable		 1og5A-4dnhA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_A_FUAA702_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4dnh UNCHARACTERIZED
PROTEIN
(Sinorhizobium
meliloti) 		5 / 12 THR A 309
PHE A 302
LEU A 291
ALA A  41
ALA A  40
 None
 1.31A 1q23A-4dnhA:
undetectable
1q23B-4dnhA:
undetectable		 1q23A-4dnhA:
17.51
1q23B-4dnhA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZY_A_CHDA237_0
(PHOSPHOLIPASE A2,
MAJOR ISOENZYME)		 4dnh UNCHARACTERIZED
PROTEIN
(Sinorhizobium
meliloti) 		5 / 11 ILE A 154
ILE A 144
GLY A 229
LEU A 180
TYR A 176
 None
 1.10A 2azyA-4dnhA:
undetectable		 2azyA-4dnhA:
12.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_A_BEZA352_0
(D-AMINO-ACID OXIDASE)		 4dnh UNCHARACTERIZED
PROTEIN
(Sinorhizobium
meliloti) 		4 / 6 LEU A 180
TYR A 176
ILE A 189
GLY A 121
 None
 0.93A 2du8A-4dnhA:
undetectable		 2du8A-4dnhA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HYY_C_STIC600_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 4dnh UNCHARACTERIZED
PROTEIN
(Sinorhizobium
meliloti) 		4 / 6 LEU A 200
VAL A 242
MET A 243
ILE A 232
 None
 1.04A 2hyyC-4dnhA:
undetectable		 2hyyC-4dnhA:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A35_A_RBFA191_1
(LUMAZINE PROTEIN)		 4dnh UNCHARACTERIZED
PROTEIN
(Sinorhizobium
meliloti) 		5 / 12 VAL A 310
SER A 313
LEU A 312
THR A 309
ALA A 282
 None
 1.17A 3a35A-4dnhA:
undetectable		 3a35A-4dnhA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A35_B_RBFB191_1
(LUMAZINE PROTEIN)		 4dnh UNCHARACTERIZED
PROTEIN
(Sinorhizobium
meliloti) 		5 / 12 VAL A 310
SER A 313
LEU A 312
THR A 309
ALA A 282
 None
 1.17A 3a35B-4dnhA:
undetectable		 3a35B-4dnhA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A3B_A_RBFA191_1
(LUMAZINE PROTEIN)		 4dnh UNCHARACTERIZED
PROTEIN
(Sinorhizobium
meliloti) 		5 / 12 VAL A 310
SER A 313
LEU A 312
THR A 309
ALA A 282
 None
 1.17A 3a3bA-4dnhA:
undetectable		 3a3bA-4dnhA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYX_A_ROCA201_2
(HIV-1 PROTEASE)		 4dnh UNCHARACTERIZED
PROTEIN
(Sinorhizobium
meliloti) 		3 / 3 ARG A 361
VAL A   4
THR A 376
 None
 0.78A 3cyxA-4dnhA:
undetectable		 3cyxA-4dnhA:
15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_B_SAMB301_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 4dnh UNCHARACTERIZED
PROTEIN
(Sinorhizobium
meliloti) 		5 / 12 TYR A 324
ILE A 232
ILE A 189
ILE A 155
LEU A 192
 None
None
None
None
GOL  A 500 (-4.9A)
 1.11A 3fpjB-4dnhA:
undetectable		 3fpjB-4dnhA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS6_A_EPAA1_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4dnh UNCHARACTERIZED
PROTEIN
(Sinorhizobium
meliloti) 		5 / 12 TYR A 261
GLY A 367
ALA A 366
LEU A 362
LEU A 359
 None
 1.01A 3hs6A-4dnhA:
undetectable		 3hs6A-4dnhA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SP9_A_IL2A901_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA)		 4dnh UNCHARACTERIZED
PROTEIN
(Sinorhizobium
meliloti) 		5 / 12 LEU A 234
CYH A 216
THR A 215
ILE A 173
ILE A 189
 None
 1.27A 3sp9A-4dnhA:
undetectable		 3sp9A-4dnhA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UA1_A_08YA600_1
(CYTOCHROME P450 3A4)		 4dnh UNCHARACTERIZED
PROTEIN
(Sinorhizobium
meliloti) 		5 / 12 ASP A 228
ARG A 153
ILE A 101
ALA A  86
ALA A  40
 None
 1.09A 3ua1A-4dnhA:
undetectable		 3ua1A-4dnhA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_B_ADNB401_2
(PUTATIVE ADENOSINE
KINASE)		 4dnh UNCHARACTERIZED
PROTEIN
(Sinorhizobium
meliloti) 		4 / 5 LEU A  19
ALA A 363
MET A 379
THR A 376
 None
 1.35A 3vasB-4dnhA:
undetectable		 3vasB-4dnhA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WSJ_A_MK1A201_1
(PROTEASE)		 4dnh UNCHARACTERIZED
PROTEIN
(Sinorhizobium
meliloti) 		5 / 9 LEU A 105
ALA A 114
ASP A 113
VAL A  79
ILE A 116
 None
 1.43A 3wsjA-4dnhA:
undetectable		 3wsjA-4dnhA:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2X_G_TMQG202_1
(DIHYDROFOLATE
REDUCTASE)		 4dnh UNCHARACTERIZED
PROTEIN
(Sinorhizobium
meliloti) 		5 / 12 ALA A 212
LEU A 247
PRO A 248
VAL A 251
ILE A 232
 None
 0.96A 4m2xG-4dnhA:
undetectable		 4m2xG-4dnhA:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N6P_A_JMSA713_1
(LACTOTRANSFERRIN)		 4dnh UNCHARACTERIZED
PROTEIN
(Sinorhizobium
meliloti) 		4 / 4 HIS A  43
ALA A  86
VAL A  44
GLU A  81
 None
 1.45A 4n6pA-4dnhA:
undetectable		 4n6pA-4dnhA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1Z_B_MXMB807_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 4dnh UNCHARACTERIZED
PROTEIN
(Sinorhizobium
meliloti) 		5 / 12 MET A 379
VAL A 382
LEU A 383
SER A 352
LEU A 353
 None
 1.02A 4o1zB-4dnhA:
undetectable		 4o1zB-4dnhA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QB9_F_PARF500_1
(ENHANCED
INTRACELLULAR
SURVIVAL PROTEIN)		 4dnh UNCHARACTERIZED
PROTEIN
(Sinorhizobium
meliloti) 		5 / 11 SER A 159
TYR A 203
GLU A  81
ASP A 197
GLY A 119
 None
 1.40A 4qb9F-4dnhA:
0.4		 4qb9F-4dnhA:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QN9_B_DXCB610_0
(N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D)		 4dnh UNCHARACTERIZED
PROTEIN
(Sinorhizobium
meliloti) 		3 / 3 GLY A 168
PRO A 169
ALA A 212
 None
 0.47A 4qn9B-4dnhA:
1.7		 4qn9B-4dnhA:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQE_A_AG2A506_1
(HOMOSPERMIDINE
SYNTHASE)		 4dnh UNCHARACTERIZED
PROTEIN
(Sinorhizobium
meliloti) 		4 / 6 ARG A 378
ARG A  64
ASP A 339
VAL A 329
 None
 1.41A 4xqeA-4dnhA:
undetectable		 4xqeA-4dnhA:
24.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XZK_A_AG2A700_1
(PUTATIVE
NAD(+)--ARGININE
ADP-RIBOSYLTRANSFERA
SE VIS)		 4dnh UNCHARACTERIZED
PROTEIN
(Sinorhizobium
meliloti) 		4 / 7 SER A 104
ARG A  88
SER A  82
GLU A  81
 None
 1.42A 4xzkA-4dnhA:
undetectable		 4xzkA-4dnhA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z2E_F_TR6F101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
SYMMETRIZED E-SITE
DNA)		 4dnh UNCHARACTERIZED
PROTEIN
(Sinorhizobium
meliloti) 		4 / 5 GLY A 297
ARG A 298
GLY A 300
GLU A 301
 None
 1.05A 4z2eB-4dnhA:
undetectable
4z2eC-4dnhA:
undetectable		 4z2eB-4dnhA:
24.34
4z2eC-4dnhA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_N_EVPN2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 4dnh UNCHARACTERIZED
PROTEIN
(Sinorhizobium
meliloti) 		4 / 6 SER A 233
GLY A  89
ASP A 123
ARG A  88
 GOL  A 500 (-2.6A)
None
None
None
 0.82A 5cdnR-4dnhA:
undetectable
5cdnS-4dnhA:
undetectable		 5cdnR-4dnhA:
23.20
5cdnS-4dnhA:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSA_A_X2NA590_1
(CYP51 VARIANT1)		 4dnh UNCHARACTERIZED
PROTEIN
(Sinorhizobium
meliloti) 		5 / 12 ALA A 350
LEU A 334
PHE A 330
LEU A 383
HIS A 386
 None
 1.13A 5fsaA-4dnhA:
undetectable		 5fsaA-4dnhA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GS4_A_ESTA603_1
(ESTROGEN RECEPTOR)		 4dnh UNCHARACTERIZED
PROTEIN
(Sinorhizobium
meliloti) 		5 / 12 THR A 376
LEU A 374
ALA A 375
GLY A  21
LEU A  19
 None
 0.90A 5gs4A-4dnhA:
undetectable		 5gs4A-4dnhA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA501_2
(CYTOCHROME P450 2C9)		 4dnh UNCHARACTERIZED
PROTEIN
(Sinorhizobium
meliloti) 		4 / 4 PHE A 317
LEU A 306
LEU A 277
VAL A 310
 None
None
GOL  A 500 (-4.7A)
None
 1.21A 5xxiA-4dnhA:
undetectable		 5xxiA-4dnhA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZW4_A_SAMA302_0
(PUTATIVE
O-METHYLTRANSFERASE
YRRM)		 4dnh UNCHARACTERIZED
PROTEIN
(Sinorhizobium
meliloti) 		5 / 12 ALA A  31
ALA A 287
ALA A  38
ALA A 275
PHE A 280
 None
 1.05A 5zw4A-4dnhA:
undetectable		 5zw4A-4dnhA:
21.64