SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4dni'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BDM_A_TMIA501_1
(CYTOCHROME P450 2B4)		 4dni FUSION PROTEIN OF
RNA-EDITING COMPLEX
PROTEINS MP42 AND
MP18
(Trypanosoma
brucei) 		4 / 7 SER A 144
LEU A 112
GLY A  51
THR A  73
 None
 0.90A 2bdmA-4dniA:
undetectable		 2bdmA-4dniA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R55_A_PZAA598_0
(LACTOPEROXIDASE)		 4dni FUSION PROTEIN OF
RNA-EDITING COMPLEX
PROTEINS MP42 AND
MP18
(Trypanosoma
brucei;
Trypanosoma
brucei) 		3 / 3 GLU A 109
PHE A 111
GLN A 104
 None
 0.97A 3r55A-4dniA:
undetectable		 3r55A-4dniA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_E_ZPCE1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4dni FUSION PROTEIN OF
RNA-EDITING COMPLEX
PROTEINS MP42 AND
MP18
(Trypanosoma
brucei) 		4 / 6 GLU A 244
TYR A 131
HIS A 132
PHE A 251
 None
 1.16A 4a97E-4dniA:
undetectable		 4a97E-4dniA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_C_MXMC606_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4dni FUSION PROTEIN OF
RNA-EDITING COMPLEX
PROTEINS MP42 AND
MP18
(Trypanosoma
brucei) 		3 / 3 LEU A  67
ARG A  91
MET A 119
 None
 0.92A 4m11C-4dniA:
undetectable		 4m11C-4dniA:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA306_1
(CHITOSANASE)		 4dni FUSION PROTEIN OF
RNA-EDITING COMPLEX
PROTEINS MP42 AND
MP18
(Trypanosoma
brucei) 		3 / 3 SER A  79
ASP A  82
GLN A 257
 None
 0.84A 4oltA-4dniA:
undetectable
4oltB-4dniA:
undetectable		 4oltA-4dniA:
20.36
4oltB-4dniA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA306_1
(CHITOSANASE)		 4dni FUSION PROTEIN OF
RNA-EDITING COMPLEX
PROTEINS MP42 AND
MP18
(Trypanosoma
brucei) 		3 / 3 SER A  79
ASP A  84
GLN A 257
 None
 0.83A 4oltA-4dniA:
undetectable
4oltB-4dniA:
undetectable		 4oltA-4dniA:
20.36
4oltB-4dniA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q5M_A_ROCA1101_3
(PROTEASE)		 4dni FUSION PROTEIN OF
RNA-EDITING COMPLEX
PROTEINS MP42 AND
MP18
(Trypanosoma
brucei) 		3 / 3 ASP A  82
ASP A  84
ASN A 161
 None
 0.77A 4q5mA-4dniA:
undetectable		 4q5mA-4dniA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB304_1
(CHITOSANASE)		 4dni FUSION PROTEIN OF
RNA-EDITING COMPLEX
PROTEINS MP42 AND
MP18
(Trypanosoma
brucei) 		3 / 3 GLN A 257
SER A  79
ASP A  84
 None
 0.76A 4qwpA-4dniA:
undetectable
4qwpB-4dniA:
undetectable		 4qwpA-4dniA:
20.36
4qwpB-4dniA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ICX_F_SC2F1_1
(CETUXIMAB FAB LIGHT
CHAIN
MEDITOPE)		 4dni FUSION PROTEIN OF
RNA-EDITING COMPLEX
PROTEINS MP42 AND
MP18
(Trypanosoma
brucei) 		3 / 3 VAL A 233
GLN A 184
CYH A 212
 None
 0.74A 5icxC-4dniA:
undetectable
5icxF-4dniA:
undetectable		 5icxC-4dniA:
20.00
5icxF-4dniA:
6.81