SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4dny'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IE9_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 4dny METALLOPROTEASE STCE
(Escherichia
coli) 		5 / 12 LEU A 174
LEU A 201
VAL A 180
HIS A 173
LEU A 162
 None
 1.35A 1ie9A-4dnyA:
undetectable		 1ie9A-4dnyA:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP2_B_PNNB5002_0
(TRANSCRIPTIONAL
REGULATOR TCAR)		 4dny METALLOPROTEASE STCE
(Escherichia
coli) 		4 / 5 ASN A 186
ALA A 212
ALA A 185
ARG A 188
 None
 1.33A 3kp2B-4dnyA:
undetectable		 3kp2B-4dnyA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQW_J_ACHJ323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)		 4dny METALLOPROTEASE STCE
(Escherichia
coli) 		4 / 8 GLU A 247
TYR A 220
LEU A 195
PHE A 208
 None
 1.09A 3rqwF-4dnyA:
undetectable
3rqwJ-4dnyA:
undetectable		 3rqwF-4dnyA:
17.52
3rqwJ-4dnyA:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G8Z_X_TOPX301_1
(DIHYDROFOLATE
REDUCTASE)		 4dny METALLOPROTEASE STCE
(Escherichia
coli) 		5 / 10 ILE A 152
LEU A 162
GLU A 158
PRO A 196
THR A 155
 None
 1.24A 4g8zX-4dnyA:
undetectable		 4g8zX-4dnyA:
19.34