SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4dou'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEA_B_ACAB90_1
(PLASMINOGEN)
4dou ADIPONECTIN
(Homo
sapiens)
4 / 7 ASP A 368
TYR A 186
ARG A 221
TYR A 216
None
1.45A 1ceaB-4douA:
undetectable
1ceaB-4douA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XVA_A_SAMA293_0
(GLYCINE
N-METHYLTRANSFERASE)
4dou ADIPONECTIN
(Homo
sapiens)
5 / 12 THR A 374
SER A 480
HIS A 163
GLY A 377
TYR A 159
None
1.43A 1xvaA-4douA:
undetectable
1xvaA-4douA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_A_SAMA2001_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)
4dou ADIPONECTIN
(Homo
sapiens)
4 / 7 TYR A 327
TYR A 471
ASP A 509
ASN A 512
None
None
None
EDO  A1009 ( 4.5A)
1.02A 2g70A-4douA:
undetectable
2g70A-4douA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_A_SAMA2001_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)
4dou ADIPONECTIN
(Homo
sapiens)
4 / 6 TYR A 327
TYR A 471
ASP A 509
ASN A 512
None
None
None
EDO  A1009 ( 4.5A)
1.03A 2g72A-4douA:
undetectable
2g72A-4douA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1351_1
(PROSTAGLANDIN
REDUCTASE 2)
4dou ADIPONECTIN
(Homo
sapiens)
5 / 10 PHE A 273
TYR A 159
TYR A 300
LEU A 316
LEU A 354
None
1.40A 2w98A-4douA:
undetectable
2w98A-4douA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_C_ACHC1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)
4dou ADIPONECTIN
(Homo
sapiens)
4 / 8 THR A 233
SER A 116
TYR A 159
TYR A 441
None
1.41A 2xz5A-4douA:
undetectable
2xz5C-4douA:
undetectable
2xz5A-4douA:
19.86
2xz5C-4douA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWI_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)
4dou ADIPONECTIN
(Homo
sapiens)
5 / 7 TYR A 162
THR A 185
LEU A 183
VAL A 201
THR A 376
None
1.48A 3fwiA-4douA:
undetectable
3fwiA-4douA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWI_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)
4dou ADIPONECTIN
(Homo
sapiens)
5 / 7 TYR A 444
THR A 467
LEU A 465
VAL A 483
THR A 235
None
1.44A 3fwiA-4douA:
undetectable
3fwiA-4douA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WXO_A_NIZA803_1
(CATALASE-PEROXIDASE)
4dou ADIPONECTIN
(Homo
sapiens)
4 / 4 ASP A 231
THR A 467
VAL A 483
SER A 456
None
1.10A 3wxoA-4douA:
undetectable
3wxoA-4douA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WXO_A_NIZA803_1
(CATALASE-PEROXIDASE)
4dou ADIPONECTIN
(Homo
sapiens)
4 / 4 ASP A 372
THR A 185
VAL A 201
SER A 174
None
1.13A 3wxoA-4douA:
undetectable
3wxoA-4douA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WXO_A_NIZA803_1
(CATALASE-PEROXIDASE)
4dou ADIPONECTIN
(Homo
sapiens)
4 / 4 ASP A 513
THR A 326
VAL A 342
SER A 315
None
1.16A 3wxoA-4douA:
undetectable
3wxoA-4douA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X3U_B_SVRB102_1
(CHROMOBOX PROTEIN
HOMOLOG 7)
4dou ADIPONECTIN
(Homo
sapiens)
3 / 3 LYS A 407
ARG A 503
VAL A 453
None
0.62A 4x3uA-4douA:
undetectable
4x3uB-4douA:
undetectable
4x3uA-4douA:
8.41
4x3uB-4douA:
8.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_G_ZOLG401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)
4dou ADIPONECTIN
(Homo
sapiens)
4 / 7 ASP A 336
ASP A 195
GLN A 472
TYR A 471
CA  A1003 ( 3.2A)
CA  A1003 ( 3.2A)
None
None
1.43A 6g31G-4douA:
undetectable
6g31G-4douA:
11.17