SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4dp0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1LH6_A_NIOA155_1 (LEGHEMOGLOBIN A (NICOTINATE MET))	4dp0	PLASTOCYANIN B, CHLOROPLASTIC (Populus nigra)	4 / 7	PHE X 29 PHE X 82 PHE X 41 VAL X 1	None	0.99A	1lh6A-4dp0X: undetectable	1lh6A-4dp0X: 22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1OE1_A_CUA501_0 (DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE)	4dp0	PLASTOCYANIN B, CHLOROPLASTIC (Populus nigra)	4 / 4	HIS X 37 CYH X 84 HIS X 87 MET X 92	CU X 100 (-3.1A) CU X 100 (-2.2A) CU X 100 ( 3.1A) CU X 100 (-2.5A)	0.42A	1oe1A-4dp0X: 3.2	1oe1A-4dp0X: 15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1OE2_A_CUA501_0 (DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE)	4dp0	PLASTOCYANIN B, CHLOROPLASTIC (Populus nigra)	5 / 5	HIS X 37 CYH X 84 PRO X 86 HIS X 87 MET X 92	CU X 100 (-3.1A) CU X 100 (-2.2A) None CU X 100 ( 3.1A) CU X 100 (-2.5A)	0.76A	1oe2A-4dp0X: 6.5	1oe2A-4dp0X: 15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1OE3_A_CUA501_0 (DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE)	4dp0	PLASTOCYANIN B, CHLOROPLASTIC (Populus nigra)	4 / 4	HIS X 37 CYH X 84 HIS X 87 MET X 92	CU X 100 (-3.1A) CU X 100 (-2.2A) CU X 100 ( 3.1A) CU X 100 (-2.5A)	0.45A	1oe3A-4dp0X: 3.9	1oe3A-4dp0X: 15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2FQD_A_CUA601_0 (BLUE COPPER OXIDASE CUEO)	4dp0	PLASTOCYANIN B, CHLOROPLASTIC (Populus nigra)	4 / 4	HIS X 37 CYH X 84 HIS X 87 MET X 92	CU X 100 (-3.1A) CU X 100 (-2.2A) CU X 100 ( 3.1A) CU X 100 (-2.5A)	0.42A	2fqdA-4dp0X: undetectable	2fqdA-4dp0X: 12.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2FQE_A_CUA601_0 (BLUE COPPER OXIDASE CUEO)	4dp0	PLASTOCYANIN B, CHLOROPLASTIC (Populus nigra)	4 / 4	HIS X 37 CYH X 84 HIS X 87 MET X 92	CU X 100 (-3.1A) CU X 100 (-2.2A) CU X 100 ( 3.1A) CU X 100 (-2.5A)	0.39A	2fqeA-4dp0X: undetectable	2fqeA-4dp0X: 12.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2FQF_A_CUA601_0 (BLUE COPPER OXIDASE CUEO)	4dp0	PLASTOCYANIN B, CHLOROPLASTIC (Populus nigra)	4 / 4	HIS X 37 CYH X 84 HIS X 87 MET X 92	CU X 100 (-3.1A) CU X 100 (-2.2A) CU X 100 ( 3.1A) CU X 100 (-2.5A)	0.38A	2fqfA-4dp0X: undetectable	2fqfA-4dp0X: 12.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2FQG_A_CUA601_0 (BLUE COPPER OXIDASE CUEO)	4dp0	PLASTOCYANIN B, CHLOROPLASTIC (Populus nigra)	4 / 4	HIS X 37 CYH X 84 HIS X 87 MET X 92	CU X 100 (-3.1A) CU X 100 (-2.2A) CU X 100 ( 3.1A) CU X 100 (-2.5A)	0.37A	2fqgA-4dp0X: undetectable	2fqgA-4dp0X: 12.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XXG_A_CUA1337_0 (DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE)	4dp0	PLASTOCYANIN B, CHLOROPLASTIC (Populus nigra)	4 / 4	HIS X 37 CYH X 84 HIS X 87 MET X 92	CU X 100 (-3.1A) CU X 100 (-2.2A) CU X 100 ( 3.1A) CU X 100 (-2.5A)	0.44A	2xxgA-4dp0X: 5.8	2xxgA-4dp0X: 14.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XXG_C_CUC1338_0 (DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE)	4dp0	PLASTOCYANIN B, CHLOROPLASTIC (Populus nigra)	5 / 5	HIS X 37 CYH X 84 PRO X 86 HIS X 87 MET X 92	CU X 100 (-3.1A) CU X 100 (-2.2A) None CU X 100 ( 3.1A) CU X 100 (-2.5A)	0.81A	2xxgC-4dp0X: 6.7	2xxgC-4dp0X: 14.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KPD_B_SAMB1000_1 (UNCHARACTERIZED PROTEIN MJ0100)	4dp0	PLASTOCYANIN B, CHLOROPLASTIC (Populus nigra)	3 / 3	ASN X 38 ASN X 64 GLU X 68	None	0.92A	3kpdC-4dp0X: undetectable	3kpdC-4dp0X: 24.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KPD_C_SAMC1000_0 (UNCHARACTERIZED PROTEIN MJ0100)	4dp0	PLASTOCYANIN B, CHLOROPLASTIC (Populus nigra)	3 / 3	ASN X 38 ASN X 64 GLU X 68	None	0.81A	3kpdB-4dp0X: undetectable	3kpdB-4dp0X: 24.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4EF3_A_CUA1001_0 (BLUE COPPER OXIDASE CUEO)	4dp0	PLASTOCYANIN B, CHLOROPLASTIC (Populus nigra)	4 / 4	HIS X 37 CYH X 84 HIS X 87 MET X 92	CU X 100 (-3.1A) CU X 100 (-2.2A) CU X 100 ( 3.1A) CU X 100 (-2.5A)	0.35A	4ef3A-4dp0X: undetectable	4ef3A-4dp0X: 12.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MVM_B_PFLB510_1 (PROTON-GATED ION CHANNEL)	4dp0	PLASTOCYANIN B, CHLOROPLASTIC (Populus nigra)	4 / 6	ILE X 27 ALA X 73 LEU X 74 ILE X 55	None	0.66A	5mvmB-4dp0X: undetectable 5mvmC-4dp0X: undetectable	5mvmB-4dp0X: 22.52 5mvmC-4dp0X: 22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6HUO_D_08HD501_0 (GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT ALPHA-1,GAMMA-AMINOB UTYRIC ACID RECEPTOR SUBUNIT ALPHA-1 GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT GAMMA-2)	4dp0	PLASTOCYANIN B, CHLOROPLASTIC (Populus nigra)	4 / 8	TYR X 80 PHE X 41 PHE X 29 VAL X 21	None	1.02A	6huoC-4dp0X: undetectable 6huoD-4dp0X: undetectable	6huoC-4dp0X: 23.23 6huoD-4dp0X: 19.19

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1LH6_A_NIOA155_1","LEGHEMOGLOBIN A (NICOTINATE MET)","4dp0","PLASTOCYANIN B, CHLOROPLASTIC","Populus nigra",4,"PHE X  29;PHE X  82;PHE X  41;VAL X   1","None","0.99A","1lh6A-4dp0X:undetectable","1lh6A-4dp0X:22.88"],["1OE1_A_CUA501_0","DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE","4dp0","PLASTOCYANIN B, CHLOROPLASTIC","Populus nigra",4,"HIS X  37;CYH X  84;HIS X  87;MET X  92"," CU X 100 (-3.1A); CU X 100 (-2.2A); CU X 100 ( 3.1A); CU X 100 (-2.5A)","0.42A","1oe1A-4dp0X:3.2","1oe1A-4dp0X:15.09"],["1OE2_A_CUA501_0","DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE","4dp0","PLASTOCYANIN B, CHLOROPLASTIC","Populus nigra",5,"HIS X  37;CYH X  84;PRO X  86;HIS X  87;MET X  92"," CU X 100 (-3.1A); CU X 100 (-2.2A);None; CU X 100 ( 3.1A); CU X 100 (-2.5A)","0.76A","1oe2A-4dp0X:6.5","1oe2A-4dp0X:15.09"],["1OE3_A_CUA501_0","DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE","4dp0","PLASTOCYANIN B, CHLOROPLASTIC","Populus nigra",4,"HIS X  37;CYH X  84;HIS X  87;MET X  92"," CU X 100 (-3.1A); CU X 100 (-2.2A); CU X 100 ( 3.1A); CU X 100 (-2.5A)","0.45A","1oe3A-4dp0X:3.9","1oe3A-4dp0X:15.09"],["2FQD_A_CUA601_0","BLUE COPPER OXIDASE CUEO","4dp0","PLASTOCYANIN B, CHLOROPLASTIC","Populus nigra",4,"HIS X  37;CYH X  84;HIS X  87;MET X  92"," CU X 100 (-3.1A); CU X 100 (-2.2A); CU X 100 ( 3.1A); CU X 100 (-2.5A)","0.42A","2fqdA-4dp0X:undetectable","2fqdA-4dp0X:12.35"],["2FQE_A_CUA601_0","BLUE COPPER OXIDASE CUEO","4dp0","PLASTOCYANIN B, CHLOROPLASTIC","Populus nigra",4,"HIS X  37;CYH X  84;HIS X  87;MET X  92"," CU X 100 (-3.1A); CU X 100 (-2.2A); CU X 100 ( 3.1A); CU X 100 (-2.5A)","0.39A","2fqeA-4dp0X:undetectable","2fqeA-4dp0X:12.35"],["2FQF_A_CUA601_0","BLUE COPPER OXIDASE CUEO","4dp0","PLASTOCYANIN B, CHLOROPLASTIC","Populus nigra",4,"HIS X  37;CYH X  84;HIS X  87;MET X  92"," CU X 100 (-3.1A); CU X 100 (-2.2A); CU X 100 ( 3.1A); CU X 100 (-2.5A)","0.38A","2fqfA-4dp0X:undetectable","2fqfA-4dp0X:12.35"],["2FQG_A_CUA601_0","BLUE COPPER OXIDASE CUEO","4dp0","PLASTOCYANIN B, CHLOROPLASTIC","Populus nigra",4,"HIS X  37;CYH X  84;HIS X  87;MET X  92"," CU X 100 (-3.1A); CU X 100 (-2.2A); CU X 100 ( 3.1A); CU X 100 (-2.5A)","0.37A","2fqgA-4dp0X:undetectable","2fqgA-4dp0X:12.35"],["2XXG_A_CUA1337_0","DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE","4dp0","PLASTOCYANIN B, CHLOROPLASTIC","Populus nigra",4,"HIS X  37;CYH X  84;HIS X  87;MET X  92"," CU X 100 (-3.1A); CU X 100 (-2.2A); CU X 100 ( 3.1A); CU X 100 (-2.5A)","0.44A","2xxgA-4dp0X:5.8","2xxgA-4dp0X:14.79"],["2XXG_C_CUC1338_0","DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE","4dp0","PLASTOCYANIN B, CHLOROPLASTIC","Populus nigra",5,"HIS X  37;CYH X  84;PRO X  86;HIS X  87;MET X  92"," CU X 100 (-3.1A); CU X 100 (-2.2A);None; CU X 100 ( 3.1A); CU X 100 (-2.5A)","0.81A","2xxgC-4dp0X:6.7","2xxgC-4dp0X:14.79"],["3KPD_B_SAMB1000_1","UNCHARACTERIZED PROTEIN MJ0100","4dp0","PLASTOCYANIN B, CHLOROPLASTIC","Populus nigra",3,"ASN X  38;ASN X  64;GLU X  68","None","0.92A","3kpdC-4dp0X:undetectable","3kpdC-4dp0X:24.80"],["3KPD_C_SAMC1000_0","UNCHARACTERIZED PROTEIN MJ0100","4dp0","PLASTOCYANIN B, CHLOROPLASTIC","Populus nigra",3,"ASN X  38;ASN X  64;GLU X  68","None","0.81A","3kpdB-4dp0X:undetectable","3kpdB-4dp0X:24.80"],["4EF3_A_CUA1001_0","BLUE COPPER OXIDASE CUEO","4dp0","PLASTOCYANIN B, CHLOROPLASTIC","Populus nigra",4,"HIS X  37;CYH X  84;HIS X  87;MET X  92"," CU X 100 (-3.1A); CU X 100 (-2.2A); CU X 100 ( 3.1A); CU X 100 (-2.5A)","0.35A","4ef3A-4dp0X:undetectable","4ef3A-4dp0X:12.33"],["5MVM_B_PFLB510_1","PROTON-GATED ION CHANNEL;PROTON-GATED ION CHANNEL","4dp0","PLASTOCYANIN B, CHLOROPLASTIC","Populus nigra",4,"ILE X  27;ALA X  73;LEU X  74;ILE X  55","None","0.66A","5mvmB-4dp0X:undetectable;5mvmC-4dp0X:undetectable","5mvmB-4dp0X:22.52;5mvmC-4dp0X:22.52"],["6HUO_D_08HD501_0","GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT ALPHA-1,GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT ALPHA-1;GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT GAMMA-2","4dp0","PLASTOCYANIN B, CHLOROPLASTIC","Populus nigra",4,"TYR X  80;PHE X  41;PHE X  29;VAL X  21","None","1.02A","6huoC-4dp0X:undetectable;6huoD-4dp0X:undetectable","6huoC-4dp0X:23.23;6huoD-4dp0X:19.19"]]