SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4dq1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AXW_A_MTXA732_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		6 / 12 ILE A  84
LEU A 198
ASP A 224
GLY A 228
PHE A 231
TYR A 264
 None
None
None
UMP  A 501 ( 4.0A)
None
UMP  A 501 (-4.2A)
 1.08A 1axwA-4dq1A:
36.4		 1axwA-4dq1A:
49.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AXW_A_MTXA732_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		6 / 12 LYS A  53
ILE A  84
LEU A 198
ASP A 224
GLY A 228
TYR A 264
 None
None
None
None
UMP  A 501 ( 4.0A)
UMP  A 501 (-4.2A)
 0.95A 1axwA-4dq1A:
36.4		 1axwA-4dq1A:
49.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AXW_A_MTXA732_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		6 / 12 LYS A  53
LEU A 198
ASP A 224
LEU A 227
GLY A 228
TYR A 264
 None
None
None
None
UMP  A 501 ( 4.0A)
UMP  A 501 (-4.2A)
 0.56A 1axwA-4dq1A:
36.4		 1axwA-4dq1A:
49.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AXW_B_MTXB733_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		5 / 11 ILE A  84
ASP A 224
GLY A 228
PHE A 231
TYR A 264
 None
None
UMP  A 501 ( 4.0A)
None
UMP  A 501 (-4.2A)
 0.91A 1axwB-4dq1A:
36.3		 1axwB-4dq1A:
49.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AXW_B_MTXB733_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		5 / 11 LYS A  53
ASP A 224
LEU A 227
GLY A 228
TYR A 264
 None
None
None
UMP  A 501 ( 4.0A)
UMP  A 501 (-4.2A)
 0.32A 1axwB-4dq1A:
36.3		 1axwB-4dq1A:
49.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AXW_B_MTXB733_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		5 / 11 LYS A  53
ILE A  84
ASP A 224
GLY A 228
TYR A 264
 None
None
None
UMP  A 501 ( 4.0A)
UMP  A 501 (-4.2A)
 0.75A 1axwB-4dq1A:
36.3		 1axwB-4dq1A:
49.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1B02_A_C2FA281_0
(PROTEIN (THYMIDYLATE
SYNTHASE))		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		5 / 11 LEU A 198
ASP A 224
LEU A 227
GLY A 228
TYR A 264
 None
None
None
UMP  A 501 ( 4.0A)
UMP  A 501 (-4.2A)
 0.71A 1b02A-4dq1A:
31.4		 1b02A-4dq1A:
34.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D8C_A_SORA4000_0
(MALATE SYNTHASE G)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		3 / 3 GLN A 173
HIS A 183
PRO A 178
 None
 0.90A 1d8cA-4dq1A:
undetectable		 1d8cA-4dq1A:
18.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1HVY_A_D16A414_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		6 / 12 GLU A  63
ASP A 224
LEU A 227
GLY A 228
PHE A 231
TYR A 264
 None
None
None
UMP  A 501 ( 4.0A)
None
UMP  A 501 (-4.2A)
 0.71A 1hvyA-4dq1A:
35.1		 1hvyA-4dq1A:
45.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1HVY_A_D16A414_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		5 / 12 GLU A  63
ILE A  84
ASP A 224
PHE A 231
TYR A 264
 None
None
None
None
UMP  A 501 (-4.2A)
 0.81A 1hvyA-4dq1A:
35.1		 1hvyA-4dq1A:
45.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1HVY_B_D16B415_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		5 / 12 GLU A  63
ASP A 224
GLY A 228
PHE A 231
TYR A 264
 None
None
UMP  A 501 ( 4.0A)
None
UMP  A 501 (-4.2A)
 0.63A 1hvyB-4dq1A:
34.9		 1hvyB-4dq1A:
45.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1HVY_B_D16B415_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		5 / 12 GLU A  63
ILE A  84
ASP A 224
PHE A 231
TYR A 264
 None
None
None
None
UMP  A 501 (-4.2A)
 0.84A 1hvyB-4dq1A:
34.9		 1hvyB-4dq1A:
45.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1HVY_C_D16C416_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		6 / 11 GLU A  63
ILE A  84
ASP A 224
GLY A 228
PHE A 231
TYR A 264
 None
None
None
UMP  A 501 ( 4.0A)
None
UMP  A 501 (-4.2A)
 0.71A 1hvyC-4dq1A:
35.1		 1hvyC-4dq1A:
45.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1HVY_D_D16D417_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		6 / 12 GLU A  63
ASP A 224
LEU A 227
GLY A 228
PHE A 231
TYR A 264
 None
None
None
UMP  A 501 ( 4.0A)
None
UMP  A 501 (-4.2A)
 0.57A 1hvyD-4dq1A:
34.7		 1hvyD-4dq1A:
45.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1HVY_D_D16D417_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		6 / 12 GLU A  63
ILE A  84
LEU A 198
ASP A 224
PHE A 231
TYR A 264
 None
None
None
None
None
UMP  A 501 (-4.2A)
 0.94A 1hvyD-4dq1A:
34.7		 1hvyD-4dq1A:
45.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1HVY_D_D16D417_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		6 / 12 GLU A  63
LEU A 198
ASP A 224
LEU A 227
PHE A 231
TYR A 264
 None
None
None
None
None
UMP  A 501 (-4.2A)
 0.77A 1hvyD-4dq1A:
34.7		 1hvyD-4dq1A:
45.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1I00_A_D16A315_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		6 / 9 GLU A  63
ILE A  84
ASP A 224
GLY A 228
PHE A 231
TYR A 264
 None
None
None
UMP  A 501 ( 4.0A)
None
UMP  A 501 (-4.2A)
 0.70A 1i00A-4dq1A:
33.1		 1i00A-4dq1A:
45.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1I00_A_D16A315_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		5 / 9 GLU A  63
TRP A  85
ASP A 224
PHE A 231
TYR A 264
 None
None
None
None
UMP  A 501 (-4.2A)
 0.63A 1i00A-4dq1A:
33.1		 1i00A-4dq1A:
45.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1I00_B_D16B409_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		5 / 9 ASP A 224
LEU A 227
GLY A 228
ASN A 232
TYR A 264
 None
None
UMP  A 501 ( 4.0A)
UMP  A 501 (-2.7A)
UMP  A 501 (-4.2A)
 0.77A 1i00B-4dq1A:
33.3		 1i00B-4dq1A:
45.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1I00_B_D16B409_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		6 / 9 ILE A  84
ASP A 224
GLY A 228
PHE A 231
ASN A 232
TYR A 264
 None
None
UMP  A 501 ( 4.0A)
None
UMP  A 501 (-2.7A)
UMP  A 501 (-4.2A)
 0.45A 1i00B-4dq1A:
33.3		 1i00B-4dq1A:
45.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JU6_B_LYAB315_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		5 / 9 LYS A  53
ASP A 224
LEU A 227
GLY A 228
TYR A 264
 None
None
None
UMP  A 501 ( 4.0A)
UMP  A 501 (-4.2A)
 0.47A 1ju6B-4dq1A:
34.5		 1ju6B-4dq1A:
43.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JU6_D_LYAD315_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		5 / 11 LYS A  53
ASP A 224
LEU A 227
GLY A 228
TYR A 264
 None
None
None
UMP  A 501 ( 4.0A)
UMP  A 501 (-4.2A)
 0.48A 1ju6D-4dq1A:
34.6		 1ju6D-4dq1A:
43.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JUJ_A_LYAA315_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		5 / 10 LYS A  53
ASP A 224
LEU A 227
GLY A 228
TYR A 264
 None
None
None
UMP  A 501 ( 4.0A)
UMP  A 501 (-4.2A)
 0.43A 1jujA-4dq1A:
34.5		 1jujA-4dq1A:
43.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JUJ_B_LYAB315_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		5 / 10 LYS A  53
ASP A 224
LEU A 227
GLY A 228
TYR A 264
 None
None
None
UMP  A 501 ( 4.0A)
UMP  A 501 (-4.2A)
 0.43A 1jujB-4dq1A:
34.4		 1jujB-4dq1A:
43.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JUJ_C_LYAC315_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		5 / 10 LYS A  53
ASP A 224
LEU A 227
GLY A 228
TYR A 264
 None
None
None
UMP  A 501 ( 4.0A)
UMP  A 501 (-4.2A)
 0.43A 1jujC-4dq1A:
34.5		 1jujC-4dq1A:
43.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JUJ_D_LYAD315_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		5 / 10 LYS A  53
ASP A 224
LEU A 227
GLY A 228
TYR A 264
 None
None
None
UMP  A 501 ( 4.0A)
UMP  A 501 (-4.2A)
 0.43A 1jujD-4dq1A:
34.5		 1jujD-4dq1A:
43.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RTS_A_D16A309_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		4 / 8 ASP A 224
GLY A 228
PHE A 231
TYR A 264
 None
UMP  A 501 ( 4.0A)
None
UMP  A 501 (-4.2A)
 0.43A 1rtsA-4dq1A:
34.3		 1rtsA-4dq1A:
46.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RTS_A_D16A309_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		4 / 8 ASP A 224
LEU A 227
GLY A 228
TYR A 264
 None
None
UMP  A 501 ( 4.0A)
UMP  A 501 (-4.2A)
 0.77A 1rtsA-4dq1A:
34.3		 1rtsA-4dq1A:
46.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RTS_A_D16A309_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		4 / 8 ILE A  84
ASP A 224
PHE A 231
TYR A 264
 None
None
None
UMP  A 501 (-4.2A)
 0.59A 1rtsA-4dq1A:
34.3		 1rtsA-4dq1A:
46.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RTS_B_D16B409_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		4 / 7 ASP A 224
GLY A 228
PHE A 231
TYR A 264
 None
UMP  A 501 ( 4.0A)
None
UMP  A 501 (-4.2A)
 0.28A 1rtsB-4dq1A:
35.0		 1rtsB-4dq1A:
46.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RTS_B_D16B409_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		4 / 7 ASP A 224
LEU A 227
GLY A 228
TYR A 264
 None
None
UMP  A 501 ( 4.0A)
UMP  A 501 (-4.2A)
 0.59A 1rtsB-4dq1A:
35.0		 1rtsB-4dq1A:
46.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RTS_B_D16B409_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		4 / 7 ILE A  84
ASP A 224
PHE A 231
TYR A 264
 None
None
None
UMP  A 501 (-4.2A)
 0.58A 1rtsB-4dq1A:
35.0		 1rtsB-4dq1A:
46.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TLS_B_C2FB266_0
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		5 / 12 ILE A  84
LEU A 198
GLY A 228
PHE A 231
TYR A 264
 None
None
UMP  A 501 ( 4.0A)
None
UMP  A 501 (-4.2A)
 1.11A 1tlsB-4dq1A:
36.1		 1tlsB-4dq1A:
50.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TSN_A_C2FA266_0
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		5 / 12 ILE A  84
LEU A 198
GLY A 228
PHE A 231
TYR A 264
 None
None
UMP  A 501 ( 4.0A)
None
UMP  A 501 (-4.2A)
 1.11A 1tsnA-4dq1A:
36.1		 1tsnA-4dq1A:
50.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_B_9CRB600_1
(RETINOIC ACID
RECEPTOR, BETA)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		5 / 12 LEU A 239
LEU A 242
ILE A 243
LEU A 167
LEU A  64
 None
 0.91A 1xdkB-4dq1A:
undetectable		 1xdkB-4dq1A:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_B_9CRB600_1
(RETINOIC ACID
RECEPTOR, BETA)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		5 / 12 LEU A 239
LEU A 242
ILE A 243
SER A 289
LEU A 167
 None
 1.15A 1xdkB-4dq1A:
undetectable		 1xdkB-4dq1A:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_F_9CRF1600_1
(RETINOIC ACID
RECEPTOR, BETA)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		5 / 12 LEU A 239
LEU A 242
ILE A 243
LEU A 167
LEU A  64
 None
 0.91A 1xdkF-4dq1A:
undetectable		 1xdkF-4dq1A:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YC2_A_NCAA506_0
(NAD-DEPENDENT
DEACETYLASE 2)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		4 / 6 ALA A 223
PHE A 258
ASN A 232
ILE A 233
 UMP  A 501 (-4.2A)
None
UMP  A 501 (-2.7A)
None
 1.00A 1yc2A-4dq1A:
undetectable		 1yc2A-4dq1A:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YC2_D_NCAD510_0
(NAD-DEPENDENT
DEACETYLASE 2)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		4 / 5 ALA A 223
PHE A 258
ASN A 232
ILE A 233
 UMP  A 501 (-4.2A)
None
UMP  A 501 (-2.7A)
None
 0.95A 1yc2D-4dq1A:
undetectable		 1yc2D-4dq1A:
21.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2KCE_A_D16A566_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		5 / 12 GLU A  63
LEU A 198
ASP A 224
GLY A 228
TYR A 264
 None
None
None
UMP  A 501 ( 4.0A)
UMP  A 501 (-4.2A)
 0.69A 2kceA-4dq1A:
36.4		 2kceA-4dq1A:
50.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2KCE_A_D16A566_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		5 / 12 LEU A 198
ASP A 224
GLY A 228
PHE A 231
TYR A 264
 None
None
UMP  A 501 ( 4.0A)
None
UMP  A 501 (-4.2A)
 1.17A 2kceA-4dq1A:
36.4		 2kceA-4dq1A:
50.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2KCE_B_D16B568_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		6 / 12 LEU A 198
ASP A 224
LEU A 227
GLY A 228
PHE A 231
TYR A 264
 None
None
None
UMP  A 501 ( 4.0A)
None
UMP  A 501 (-4.2A)
 0.79A 2kceB-4dq1A:
36.2		 2kceB-4dq1A:
50.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2KCE_B_D16B568_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		5 / 12 SER A  56
ASP A 224
LEU A 227
GLY A 228
TYR A 264
 None
None
None
UMP  A 501 ( 4.0A)
UMP  A 501 (-4.2A)
 1.08A 2kceB-4dq1A:
36.2		 2kceB-4dq1A:
50.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2TSR_A_D16A309_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		4 / 7 ASP A 224
LEU A 227
GLY A 228
TYR A 264
 None
None
UMP  A 501 ( 4.0A)
UMP  A 501 (-4.2A)
 0.74A 2tsrA-4dq1A:
34.2		 2tsrA-4dq1A:
46.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2TSR_A_D16A309_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		5 / 7 ILE A  84
ASP A 224
GLY A 228
PHE A 231
TYR A 264
 None
None
UMP  A 501 ( 4.0A)
None
UMP  A 501 (-4.2A)
 0.53A 2tsrA-4dq1A:
34.2		 2tsrA-4dq1A:
46.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2TSR_C_D16C509_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		5 / 10 GLU A  63
ASP A 224
LEU A 227
GLY A 228
TYR A 264
 None
None
None
UMP  A 501 ( 4.0A)
UMP  A 501 (-4.2A)
 0.75A 2tsrC-4dq1A:
33.9		 2tsrC-4dq1A:
46.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2TSR_C_D16C509_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		6 / 10 GLU A  63
ILE A  84
ASP A 224
GLY A 228
PHE A 231
TYR A 264
 None
None
None
UMP  A 501 ( 4.0A)
None
UMP  A 501 (-4.2A)
 0.67A 2tsrC-4dq1A:
33.9		 2tsrC-4dq1A:
46.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2TSR_D_D16D609_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		5 / 9 ILE A  84
ASP A 224
GLY A 228
PHE A 231
TYR A 264
 None
None
UMP  A 501 ( 4.0A)
None
UMP  A 501 (-4.2A)
 0.60A 2tsrD-4dq1A:
34.5		 2tsrD-4dq1A:
46.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G4L_C_ROFC903_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		3 / 3 SER A 222
GLN A 220
PHE A 258
 UMP  A 501 (-2.5A)
UMP  A 501 (-4.1A)
None
 0.73A 3g4lC-4dq1A:
undetectable		 3g4lC-4dq1A:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K2H_A_LYAA513_1
(DIHYDROFOLATE
REDUCTASE/THYMIDYLAT
E SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		6 / 12 GLU A  63
LEU A 198
ASP A 224
LEU A 227
GLY A 228
TYR A 264
 None
None
None
None
UMP  A 501 ( 4.0A)
UMP  A 501 (-4.2A)
 0.88A 3k2hA-4dq1A:
33.5		 3k2hA-4dq1A:
28.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K2H_B_LYAB513_1
(DIHYDROFOLATE
REDUCTASE/THYMIDYLAT
E SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		6 / 12 GLU A  63
LEU A 198
ASP A 224
LEU A 227
GLY A 228
TYR A 264
 None
None
None
None
UMP  A 501 ( 4.0A)
UMP  A 501 (-4.2A)
 0.87A 3k2hB-4dq1A:
34.0		 3k2hB-4dq1A:
28.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UAY_A_ADNA236_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		5 / 10 GLY A  20
VAL A  16
GLU A  15
ASN A  21
ILE A  32
 None
 1.07A 3uayA-4dq1A:
undetectable		 3uayA-4dq1A:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ7_B_SAMB302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		5 / 12 LEU A  12
ILE A  19
GLY A  20
ILE A 225
HIS A  37
 None
 1.23A 3uj7B-4dq1A:
undetectable		 3uj7B-4dq1A:
20.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UWL_B_FOZB316_0
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		6 / 12 LEU A  59
LEU A 198
GLY A 228
PHE A 231
ASN A 232
TYR A 264
 None
None
UMP  A 501 ( 4.0A)
None
UMP  A 501 (-2.7A)
UMP  A 501 (-4.2A)
 1.26A 3uwlB-4dq1A:
39.4		 3uwlB-4dq1A:
65.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UWL_B_FOZB316_0
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		7 / 12 LEU A  59
LEU A 198
HIS A 202
LEU A 227
GLY A 228
ASN A 232
TYR A 264
 None
None
UMP  A 501 (-4.0A)
None
UMP  A 501 ( 4.0A)
UMP  A 501 (-2.7A)
UMP  A 501 (-4.2A)
 0.83A 3uwlB-4dq1A:
39.4		 3uwlB-4dq1A:
65.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UWL_D_FOZD316_0
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		6 / 12 LEU A  59
LEU A 198
GLY A 228
PHE A 231
ASN A 232
TYR A 264
 None
None
UMP  A 501 ( 4.0A)
None
UMP  A 501 (-2.7A)
UMP  A 501 (-4.2A)
 1.28A 3uwlD-4dq1A:
39.4		 3uwlD-4dq1A:
65.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UWL_D_FOZD316_0
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		6 / 12 LEU A  59
LEU A 198
HIS A 202
LEU A 227
GLY A 228
TYR A 264
 None
None
UMP  A 501 (-4.0A)
None
UMP  A 501 ( 4.0A)
UMP  A 501 (-4.2A)
 0.94A 3uwlD-4dq1A:
39.4		 3uwlD-4dq1A:
65.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UWL_D_FOZD316_0
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		6 / 12 LEU A  59
LEU A 198
LEU A 227
GLY A 228
ASN A 232
TYR A 264
 None
None
None
UMP  A 501 ( 4.0A)
UMP  A 501 (-2.7A)
UMP  A 501 (-4.2A)
 0.52A 3uwlD-4dq1A:
39.4		 3uwlD-4dq1A:
65.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EB4_A_D16A402_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		5 / 12 ASP A 224
GLY A 228
PHE A 231
ASN A 232
TYR A 264
 None
UMP  A 501 ( 4.0A)
None
UMP  A 501 (-2.7A)
UMP  A 501 (-4.2A)
 0.28A 4eb4A-4dq1A:
34.5		 4eb4A-4dq1A:
46.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EB4_A_D16A402_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		6 / 12 ASP A 224
LEU A 227
GLY A 228
ASN A 232
TYR A 264
LYS A 313
 None
None
UMP  A 501 ( 4.0A)
UMP  A 501 (-2.7A)
UMP  A 501 (-4.2A)
None
 0.82A 4eb4A-4dq1A:
34.5		 4eb4A-4dq1A:
46.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EB4_A_D16A402_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		5 / 12 ILE A  84
ASP A 224
PHE A 231
ASN A 232
TYR A 264
 None
None
None
UMP  A 501 (-2.7A)
UMP  A 501 (-4.2A)
 0.67A 4eb4A-4dq1A:
34.5		 4eb4A-4dq1A:
46.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EB4_B_D16B402_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		5 / 12 ASP A 224
GLY A 228
PHE A 231
ASN A 232
TYR A 264
 None
UMP  A 501 ( 4.0A)
None
UMP  A 501 (-2.7A)
UMP  A 501 (-4.2A)
 0.27A 4eb4B-4dq1A:
34.6		 4eb4B-4dq1A:
46.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EB4_B_D16B402_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		5 / 12 ASP A 224
LEU A 227
GLY A 228
ASN A 232
TYR A 264
 None
None
UMP  A 501 ( 4.0A)
UMP  A 501 (-2.7A)
UMP  A 501 (-4.2A)
 0.62A 4eb4B-4dq1A:
34.6		 4eb4B-4dq1A:
46.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EB4_B_D16B402_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		5 / 12 ASP A 224
LEU A 227
GLY A 228
TYR A 264
LYS A 313
 None
None
UMP  A 501 ( 4.0A)
UMP  A 501 (-4.2A)
None
 0.92A 4eb4B-4dq1A:
34.6		 4eb4B-4dq1A:
46.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EB4_B_D16B402_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		5 / 12 ILE A  84
ASP A 224
PHE A 231
ASN A 232
TYR A 264
 None
None
None
UMP  A 501 (-2.7A)
UMP  A 501 (-4.2A)
 0.69A 4eb4B-4dq1A:
34.6		 4eb4B-4dq1A:
46.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EB4_C_D16C402_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		5 / 9 ASP A 224
LEU A 227
GLY A 228
ASN A 232
TYR A 264
 None
None
UMP  A 501 ( 4.0A)
UMP  A 501 (-2.7A)
UMP  A 501 (-4.2A)
 0.80A 4eb4C-4dq1A:
34.0		 4eb4C-4dq1A:
46.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EB4_C_D16C402_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		6 / 9 ILE A  84
ASP A 224
GLY A 228
PHE A 231
ASN A 232
TYR A 264
 None
None
UMP  A 501 ( 4.0A)
None
UMP  A 501 (-2.7A)
UMP  A 501 (-4.2A)
 0.56A 4eb4C-4dq1A:
34.0		 4eb4C-4dq1A:
46.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EB4_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		6 / 10 ASP A 224
LEU A 227
GLY A 228
ASN A 232
TYR A 264
LYS A 313
 None
None
UMP  A 501 ( 4.0A)
UMP  A 501 (-2.7A)
UMP  A 501 (-4.2A)
None
 0.96A 4eb4D-4dq1A:
34.5		 4eb4D-4dq1A:
46.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EB4_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		7 / 10 ILE A  84
ASP A 224
GLY A 228
PHE A 231
ASN A 232
TYR A 264
LYS A 313
 None
None
UMP  A 501 ( 4.0A)
None
UMP  A 501 (-2.7A)
UMP  A 501 (-4.2A)
None
 0.73A 4eb4D-4dq1A:
34.5		 4eb4D-4dq1A:
46.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOG_A_C2FA302_0
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		6 / 11 ILE A  84
LEU A 198
ASP A 224
GLY A 228
PHE A 231
TYR A 264
 None
None
None
UMP  A 501 ( 4.0A)
None
UMP  A 501 (-4.2A)
 1.09A 4fogA-4dq1A:
36.0		 4fogA-4dq1A:
49.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOG_A_C2FA302_0
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		5 / 11 ILE A  84
TRP A  85
LEU A 198
GLY A 228
PHE A 231
 None
None
None
UMP  A 501 ( 4.0A)
None
 1.31A 4fogA-4dq1A:
36.0		 4fogA-4dq1A:
49.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOG_A_C2FA302_0
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		5 / 11 LYS A  53
LEU A 198
ASP A 224
GLY A 228
TYR A 264
 None
None
None
UMP  A 501 ( 4.0A)
UMP  A 501 (-4.2A)
 0.51A 4fogA-4dq1A:
36.0		 4fogA-4dq1A:
49.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOG_C_C2FC302_0
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		6 / 11 ILE A  84
LEU A 198
ASP A 224
GLY A 228
PHE A 231
TYR A 264
 None
None
None
UMP  A 501 ( 4.0A)
None
UMP  A 501 (-4.2A)
 1.20A 4fogC-4dq1A:
36.1		 4fogC-4dq1A:
49.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOG_D_C2FD302_0
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		6 / 11 ILE A  84
LEU A 198
ASP A 224
GLY A 228
PHE A 231
TYR A 264
 None
None
None
UMP  A 501 ( 4.0A)
None
UMP  A 501 (-4.2A)
 1.16A 4fogD-4dq1A:
36.1		 4fogD-4dq1A:
49.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOG_D_C2FD302_0
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		7 / 11 LYS A  53
ILE A  84
LEU A 198
ASP A 224
LEU A 227
GLY A 228
TYR A 264
 None
None
None
None
None
UMP  A 501 ( 4.0A)
UMP  A 501 (-4.2A)
 0.95A 4fogD-4dq1A:
36.1		 4fogD-4dq1A:
49.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_A_D16A301_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		5 / 12 GLU A  63
ILE A  84
LEU A 198
ASP A 224
TYR A 264
 None
None
None
None
UMP  A 501 (-4.2A)
 0.88A 4foxA-4dq1A:
36.2		 4foxA-4dq1A:
49.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_A_D16A301_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		5 / 12 GLU A  63
LEU A 198
ASP A 224
GLY A 228
TYR A 264
 None
None
None
UMP  A 501 ( 4.0A)
UMP  A 501 (-4.2A)
 0.64A 4foxA-4dq1A:
36.2		 4foxA-4dq1A:
49.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_A_D16A301_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		5 / 12 ILE A  84
LEU A 198
ASP A 224
PHE A 231
TYR A 264
 None
None
None
None
UMP  A 501 (-4.2A)
 1.08A 4foxA-4dq1A:
36.2		 4foxA-4dq1A:
49.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_A_D16A301_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		5 / 12 LEU A 198
ASP A 224
GLY A 228
PHE A 231
TYR A 264
 None
None
UMP  A 501 ( 4.0A)
None
UMP  A 501 (-4.2A)
 1.10A 4foxA-4dq1A:
36.2		 4foxA-4dq1A:
49.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_A_D16A301_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		5 / 12 LEU A 198
ASP A 224
LEU A 227
GLY A 228
TYR A 264
 None
None
None
UMP  A 501 ( 4.0A)
UMP  A 501 (-4.2A)
 0.63A 4foxA-4dq1A:
36.2		 4foxA-4dq1A:
49.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_B_D16B302_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		6 / 12 GLU A  63
ILE A  84
LEU A 198
ASP A 224
GLY A 228
TYR A 264
 None
None
None
None
UMP  A 501 ( 4.0A)
UMP  A 501 (-4.2A)
 0.92A 4foxB-4dq1A:
36.2		 4foxB-4dq1A:
49.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_B_D16B302_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		6 / 12 ILE A  84
LEU A 198
ASP A 224
GLY A 228
PHE A 231
TYR A 264
 None
None
None
UMP  A 501 ( 4.0A)
None
UMP  A 501 (-4.2A)
 1.20A 4foxB-4dq1A:
36.2		 4foxB-4dq1A:
49.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_B_D16B302_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		5 / 12 LEU A 198
ASP A 224
LEU A 227
GLY A 228
TYR A 264
 None
None
None
UMP  A 501 ( 4.0A)
UMP  A 501 (-4.2A)
 0.71A 4foxB-4dq1A:
36.2		 4foxB-4dq1A:
49.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_C_D16C301_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		6 / 11 GLU A  63
LEU A 198
ASP A 224
LEU A 227
GLY A 228
TYR A 264
 None
None
None
None
UMP  A 501 ( 4.0A)
UMP  A 501 (-4.2A)
 0.74A 4foxC-4dq1A:
35.9		 4foxC-4dq1A:
49.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_C_D16C301_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		5 / 11 LEU A 198
ASP A 224
GLY A 228
PHE A 231
TYR A 264
 None
None
UMP  A 501 ( 4.0A)
None
UMP  A 501 (-4.2A)
 1.16A 4foxC-4dq1A:
35.9		 4foxC-4dq1A:
49.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_D_D16D301_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		5 / 12 GLU A  63
ASP A 224
LEU A 227
GLY A 228
TYR A 264
 None
None
None
UMP  A 501 ( 4.0A)
UMP  A 501 (-4.2A)
 0.62A 4foxD-4dq1A:
36.1		 4foxD-4dq1A:
49.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_D_D16D301_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		5 / 12 GLU A  63
ILE A  84
ASP A 224
GLY A 228
TYR A 264
 None
None
None
UMP  A 501 ( 4.0A)
UMP  A 501 (-4.2A)
 0.86A 4foxD-4dq1A:
36.1		 4foxD-4dq1A:
49.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_D_D16D301_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		5 / 12 ILE A  84
ASP A 224
GLY A 228
PHE A 231
TYR A 264
 None
None
UMP  A 501 ( 4.0A)
None
UMP  A 501 (-4.2A)
 1.05A 4foxD-4dq1A:
36.1		 4foxD-4dq1A:
49.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_E_D16E301_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		5 / 12 LYS A  53
ASP A 224
LEU A 227
GLY A 228
TYR A 264
 None
None
None
UMP  A 501 ( 4.0A)
UMP  A 501 (-4.2A)
 0.50A 4foxE-4dq1A:
36.3		 4foxE-4dq1A:
49.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_E_D16E301_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		5 / 12 LYS A  53
GLU A  63
ASP A 224
GLY A 228
TYR A 264
 None
None
None
UMP  A 501 ( 4.0A)
UMP  A 501 (-4.2A)
 0.51A 4foxE-4dq1A:
36.3		 4foxE-4dq1A:
49.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_E_D16E301_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		5 / 12 LYS A  53
GLU A  63
ILE A  84
ASP A 224
TYR A 264
 None
None
None
None
UMP  A 501 (-4.2A)
 0.87A 4foxE-4dq1A:
36.3		 4foxE-4dq1A:
49.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_F_D16F301_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		5 / 11 GLU A  63
ILE A  84
LEU A 198
ASP A 224
TYR A 264
 None
None
None
None
UMP  A 501 (-4.2A)
 0.98A 4foxF-4dq1A:
36.0		 4foxF-4dq1A:
49.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_F_D16F301_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		5 / 11 GLU A  63
ILE A  84
TRP A  85
TRP A  88
LEU A 198
 None
 1.24A 4foxF-4dq1A:
36.0		 4foxF-4dq1A:
49.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_F_D16F301_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		5 / 11 GLU A  63
LEU A 198
ASP A 224
GLY A 228
TYR A 264
 None
None
None
UMP  A 501 ( 4.0A)
UMP  A 501 (-4.2A)
 0.74A 4foxF-4dq1A:
36.0		 4foxF-4dq1A:
49.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_F_D16F301_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		5 / 11 ILE A  84
LEU A 198
ASP A 224
PHE A 231
TYR A 264
 None
None
None
None
UMP  A 501 (-4.2A)
 1.16A 4foxF-4dq1A:
36.0		 4foxF-4dq1A:
49.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_F_D16F301_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		5 / 11 LEU A 198
ASP A 224
GLY A 228
PHE A 231
TYR A 264
 None
None
UMP  A 501 ( 4.0A)
None
UMP  A 501 (-4.2A)
 1.18A 4foxF-4dq1A:
36.0		 4foxF-4dq1A:
49.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_G_D16G301_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		5 / 12 GLU A  63
ILE A  84
LEU A 198
ASP A 224
TYR A 264
 None
None
None
None
UMP  A 501 (-4.2A)
 0.90A 4foxG-4dq1A:
36.1		 4foxG-4dq1A:
49.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_G_D16G301_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		6 / 12 GLU A  63
LEU A 198
ASP A 224
LEU A 227
GLY A 228
TYR A 264
 None
None
None
None
UMP  A 501 ( 4.0A)
UMP  A 501 (-4.2A)
 0.68A 4foxG-4dq1A:
36.1		 4foxG-4dq1A:
49.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_G_D16G301_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		5 / 12 ILE A  84
LEU A 198
ASP A 224
PHE A 231
TYR A 264
 None
None
None
None
UMP  A 501 (-4.2A)
 1.10A 4foxG-4dq1A:
36.1		 4foxG-4dq1A:
49.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_G_D16G301_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		5 / 12 LEU A 198
ASP A 224
GLY A 228
PHE A 231
TYR A 264
 None
None
UMP  A 501 ( 4.0A)
None
UMP  A 501 (-4.2A)
 1.16A 4foxG-4dq1A:
36.1		 4foxG-4dq1A:
49.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FQS_A_LYAA302_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		5 / 12 GLU A  63
ASP A 224
LEU A 227
GLY A 228
TYR A 264
 None
None
None
UMP  A 501 ( 4.0A)
UMP  A 501 (-4.2A)
 0.60A 4fqsA-4dq1A:
36.2		 4fqsA-4dq1A:
49.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FQS_B_LYAB302_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		5 / 12 GLU A  63
ASP A 224
LEU A 227
GLY A 228
TYR A 264
 None
None
None
UMP  A 501 ( 4.0A)
UMP  A 501 (-4.2A)
 0.61A 4fqsB-4dq1A:
36.1		 4fqsB-4dq1A:
49.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IQQ_B_D16B402_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		4 / 7 ASP A 224
LEU A 227
GLY A 228
TYR A 264
 None
None
UMP  A 501 ( 4.0A)
UMP  A 501 (-4.2A)
 0.80A 4iqqB-4dq1A:
33.0		 4iqqB-4dq1A:
44.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IQQ_B_D16B402_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		5 / 7 ILE A  84
ASP A 224
GLY A 228
PHE A 231
TYR A 264
 None
None
UMP  A 501 ( 4.0A)
None
UMP  A 501 (-4.2A)
 0.40A 4iqqB-4dq1A:
33.0		 4iqqB-4dq1A:
44.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IQQ_C_D16C402_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		4 / 7 ASP A 224
LEU A 227
GLY A 228
TYR A 264
 None
None
UMP  A 501 ( 4.0A)
UMP  A 501 (-4.2A)
 0.70A 4iqqC-4dq1A:
33.3		 4iqqC-4dq1A:
44.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IQQ_C_D16C402_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		5 / 7 ILE A  84
ASP A 224
GLY A 228
PHE A 231
TYR A 264
 None
None
UMP  A 501 ( 4.0A)
None
UMP  A 501 (-4.2A)
 0.39A 4iqqC-4dq1A:
33.3		 4iqqC-4dq1A:
44.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZC_B_ACTB401_0
(PROTON-GATED ION
CHANNEL)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		4 / 6 ILE A  68
PHE A 294
ILE A 171
GLU A 246
 None
 1.41A 4zzcB-4dq1A:
undetectable
4zzcC-4dq1A:
undetectable		 4zzcB-4dq1A:
25.07
4zzcC-4dq1A:
25.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5FCT_A_C2FA402_0
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		5 / 11 LEU A 198
ASP A 224
LEU A 227
GLY A 228
TYR A 264
 None
None
None
UMP  A 501 ( 4.0A)
UMP  A 501 (-4.2A)
 0.64A 5fctA-4dq1A:
34.6		 5fctA-4dq1A:
46.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5FCT_B_C2FB402_0
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		5 / 12 LYS A  53
VAL A  55
CYH A 201
LEU A 227
TYR A 264
 None
None
UMP  A 501 (-3.4A)
None
UMP  A 501 (-4.2A)
 0.58A 5fctB-4dq1A:
34.7		 5fctB-4dq1A:
46.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5FCT_B_C2FB402_0
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		5 / 12 LYS A  53
VAL A  55
LEU A 198
LEU A 227
TYR A 264
 None
None
None
None
UMP  A 501 (-4.2A)
 0.65A 5fctB-4dq1A:
34.7		 5fctB-4dq1A:
46.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5H3A_A_D16A401_1
(ORF70)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		5 / 7 ILE A  84
ASP A 224
GLY A 228
PHE A 231
TYR A 264
 None
None
UMP  A 501 ( 4.0A)
None
UMP  A 501 (-4.2A)
 0.53A 5h3aA-4dq1A:
33.2		 5h3aA-4dq1A:
43.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5H3A_B_D16B401_1
(ORF70)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		4 / 7 ASP A 224
LEU A 227
GLY A 228
TYR A 264
 None
None
UMP  A 501 ( 4.0A)
UMP  A 501 (-4.2A)
 0.78A 5h3aB-4dq1A:
33.7		 5h3aB-4dq1A:
43.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5H3A_B_D16B401_1
(ORF70)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		5 / 7 ILE A  84
ASP A 224
GLY A 228
PHE A 231
TYR A 264
 None
None
UMP  A 501 ( 4.0A)
None
UMP  A 501 (-4.2A)
 0.53A 5h3aB-4dq1A:
33.7		 5h3aB-4dq1A:
43.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5J7W_C_MTXC402_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		5 / 12 LEU A  59
ASP A 224
LEU A 227
GLY A 228
TYR A 264
 None
None
None
UMP  A 501 ( 4.0A)
UMP  A 501 (-4.2A)
 0.40A 5j7wC-4dq1A:
39.1		 5j7wC-4dq1A:
65.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5J7W_C_MTXC402_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		6 / 12 LEU A  59
GLU A  63
LEU A 198
LEU A 227
GLY A 228
TYR A 264
 None
None
None
None
UMP  A 501 ( 4.0A)
UMP  A 501 (-4.2A)
 0.66A 5j7wC-4dq1A:
39.1		 5j7wC-4dq1A:
65.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5J7W_C_MTXC402_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		5 / 12 LEU A  59
LEU A 198
GLY A 228
PHE A 231
TYR A 264
 None
None
UMP  A 501 ( 4.0A)
None
UMP  A 501 (-4.2A)
 1.26A 5j7wC-4dq1A:
39.1		 5j7wC-4dq1A:
65.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5J7W_D_MTXD402_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		6 / 12 GLU A  63
LEU A 198
ASP A 224
LEU A 227
GLY A 228
TYR A 264
 None
None
None
None
UMP  A 501 ( 4.0A)
UMP  A 501 (-4.2A)
 0.74A 5j7wD-4dq1A:
39.2		 5j7wD-4dq1A:
65.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC4_A_RBFA201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		5 / 12 LEU A  78
MET A 125
ALA A  89
ASN A  86
PHE A 138
 None
 1.32A 5kc4A-4dq1A:
undetectable		 5kc4A-4dq1A:
20.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NOO_A_D16A402_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		4 / 7 ASP A 224
LEU A 227
GLY A 228
TYR A 264
 None
None
UMP  A 501 ( 4.0A)
UMP  A 501 (-4.2A)
 0.80A 5nooA-4dq1A:
33.4		 5nooA-4dq1A:
44.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NOO_A_D16A402_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		5 / 7 ILE A  84
ASP A 224
GLY A 228
PHE A 231
TYR A 264
 None
None
UMP  A 501 ( 4.0A)
None
UMP  A 501 (-4.2A)
 0.52A 5nooA-4dq1A:
33.4		 5nooA-4dq1A:
44.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NOO_B_D16B402_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		4 / 7 ASP A 224
LEU A 227
GLY A 228
TYR A 264
 None
None
UMP  A 501 ( 4.0A)
UMP  A 501 (-4.2A)
 0.81A 5nooB-4dq1A:
33.4		 5nooB-4dq1A:
44.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NOO_B_D16B402_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		5 / 7 ILE A  84
ASP A 224
GLY A 228
PHE A 231
TYR A 264
 None
None
UMP  A 501 ( 4.0A)
None
UMP  A 501 (-4.2A)
 0.44A 5nooB-4dq1A:
33.4		 5nooB-4dq1A:
44.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NOO_C_D16C402_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		4 / 6 ASP A 224
GLY A 228
PHE A 231
TYR A 264
 None
UMP  A 501 ( 4.0A)
None
UMP  A 501 (-4.2A)
 0.39A 5nooC-4dq1A:
33.1		 5nooC-4dq1A:
44.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NOO_C_D16C402_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		4 / 6 ASP A 224
LEU A 227
GLY A 228
TYR A 264
 None
None
UMP  A 501 ( 4.0A)
UMP  A 501 (-4.2A)
 0.81A 5nooC-4dq1A:
33.1		 5nooC-4dq1A:
44.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X5Q_B_D16B402_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		6 / 12 GLU A  63
ASP A 224
LEU A 227
GLY A 228
PHE A 231
TYR A 264
 None
None
None
UMP  A 501 ( 4.0A)
None
UMP  A 501 (-4.2A)
 0.71A 5x5qB-4dq1A:
34.9		 5x5qB-4dq1A:
45.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X5Q_B_D16B402_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		5 / 12 GLU A  63
ILE A  84
ASP A 224
PHE A 231
TYR A 264
 None
None
None
None
UMP  A 501 (-4.2A)
 0.75A 5x5qB-4dq1A:
34.9		 5x5qB-4dq1A:
45.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X5Q_C_D16C402_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		4 / 7 ASP A 224
GLY A 228
PHE A 231
TYR A 264
 None
UMP  A 501 ( 4.0A)
None
UMP  A 501 (-4.2A)
 0.40A 5x5qC-4dq1A:
34.1		 5x5qC-4dq1A:
45.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X5Q_C_D16C402_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		4 / 7 ASP A 224
LEU A 227
GLY A 228
TYR A 264
 None
None
UMP  A 501 ( 4.0A)
UMP  A 501 (-4.2A)
 0.72A 5x5qC-4dq1A:
34.1		 5x5qC-4dq1A:
45.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X5Q_C_D16C402_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		4 / 7 ILE A  84
ASP A 224
PHE A 231
TYR A 264
 None
None
None
UMP  A 501 (-4.2A)
 0.60A 5x5qC-4dq1A:
34.1		 5x5qC-4dq1A:
45.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X5Q_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		4 / 8 ASP A 224
GLY A 228
PHE A 231
TYR A 264
 None
UMP  A 501 ( 4.0A)
None
UMP  A 501 (-4.2A)
 0.36A 5x5qD-4dq1A:
34.3		 5x5qD-4dq1A:
45.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X5Q_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		4 / 8 ASP A 224
LEU A 227
GLY A 228
TYR A 264
 None
None
UMP  A 501 ( 4.0A)
UMP  A 501 (-4.2A)
 0.72A 5x5qD-4dq1A:
34.3		 5x5qD-4dq1A:
45.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X5Q_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		4 / 8 ILE A  84
ASP A 224
PHE A 231
TYR A 264
 None
None
None
UMP  A 501 (-4.2A)
 0.61A 5x5qD-4dq1A:
34.3		 5x5qD-4dq1A:
45.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X5Q_E_D16E402_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		4 / 6 ASP A 224
LEU A 227
GLY A 228
TYR A 264
 None
None
UMP  A 501 ( 4.0A)
UMP  A 501 (-4.2A)
 0.71A 5x5qE-4dq1A:
34.1		 5x5qE-4dq1A:
45.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X5Q_E_D16E402_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		4 / 6 ILE A  84
ASP A 224
GLY A 228
TYR A 264
 None
None
UMP  A 501 ( 4.0A)
UMP  A 501 (-4.2A)
 0.64A 5x5qE-4dq1A:
34.1		 5x5qE-4dq1A:
45.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X5Q_F_D16F402_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		4 / 8 ASP A 224
GLY A 228
PHE A 231
TYR A 264
 None
UMP  A 501 ( 4.0A)
None
UMP  A 501 (-4.2A)
 0.37A 5x5qF-4dq1A:
33.8		 5x5qF-4dq1A:
45.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X5Q_F_D16F402_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		4 / 8 ASP A 224
LEU A 227
GLY A 228
TYR A 264
 None
None
UMP  A 501 ( 4.0A)
UMP  A 501 (-4.2A)
 0.73A 5x5qF-4dq1A:
33.8		 5x5qF-4dq1A:
45.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X5Q_F_D16F402_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		4 / 8 ILE A  84
ASP A 224
PHE A 231
TYR A 264
 None
None
None
UMP  A 501 (-4.2A)
 0.64A 5x5qF-4dq1A:
33.8		 5x5qF-4dq1A:
45.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X66_A_MTXA402_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		7 / 12 ILE A  84
ASP A 224
LEU A 227
GLY A 228
PHE A 231
ASN A 232
TYR A 264
 None
None
None
UMP  A 501 ( 4.0A)
None
UMP  A 501 (-2.7A)
UMP  A 501 (-4.2A)
 0.50A 5x66A-4dq1A:
34.8
5x66B-4dq1A:
24.0		 5x66A-4dq1A:
45.76
5x66B-4dq1A:
45.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X66_C_MTXC402_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		7 / 9 ILE A  84
ASP A 224
LEU A 227
GLY A 228
PHE A 231
ASN A 232
TYR A 264
 None
None
None
UMP  A 501 ( 4.0A)
None
UMP  A 501 (-2.7A)
UMP  A 501 (-4.2A)
 0.56A 5x66C-4dq1A:
35.1		 5x66C-4dq1A:
45.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X66_D_MTXD402_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		6 / 10 ILE A  84
ASP A 224
GLY A 228
PHE A 231
ASN A 232
TYR A 264
 None
None
UMP  A 501 ( 4.0A)
None
UMP  A 501 (-2.7A)
UMP  A 501 (-4.2A)
 0.52A 5x66D-4dq1A:
35.1		 5x66D-4dq1A:
45.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X66_F_MTXF402_1
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		7 / 12 LYS A  53
ILE A  84
ASP A 224
LEU A 227
GLY A 228
PHE A 231
TYR A 264
 None
None
None
None
UMP  A 501 ( 4.0A)
None
UMP  A 501 (-4.2A)
 0.61A 5x66F-4dq1A:
35.1		 5x66F-4dq1A:
45.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6QXS_B_FOZB403_0
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		5 / 12 LEU A  59
ILE A  84
LEU A 198
GLY A 228
ASN A 232
 None
None
None
UMP  A 501 ( 4.0A)
UMP  A 501 (-2.7A)
 1.08A 6qxsB-4dq1A:
39.3		 6qxsB-4dq1A:
65.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6QXS_B_FOZB403_0
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		6 / 12 LEU A  59
LEU A 198
LEU A 227
GLY A 228
ASN A 232
TYR A 264
 None
None
None
UMP  A 501 ( 4.0A)
UMP  A 501 (-2.7A)
UMP  A 501 (-4.2A)
 0.63A 6qxsB-4dq1A:
39.3		 6qxsB-4dq1A:
65.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6QXS_D_FOZD403_0
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		6 / 12 LEU A  59
LEU A 198
ASP A 224
LEU A 227
GLY A 228
ASN A 232
 None
None
None
None
UMP  A 501 ( 4.0A)
UMP  A 501 (-2.7A)
 0.57A 6qxsD-4dq1A:
39.2		 6qxsD-4dq1A:
65.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6QYA_B_FOZB401_0
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		5 / 12 LEU A  59
LEU A 198
GLY A 228
PHE A 231
TYR A 264
 None
None
UMP  A 501 ( 4.0A)
None
UMP  A 501 (-4.2A)
 1.28A 6qyaB-4dq1A:
39.2		 6qyaB-4dq1A:
65.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6QYA_B_FOZB401_0
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		5 / 12 LEU A  59
LEU A 198
LEU A 227
GLY A 228
TYR A 264
 None
None
None
UMP  A 501 ( 4.0A)
UMP  A 501 (-4.2A)
 0.47A 6qyaB-4dq1A:
39.2		 6qyaB-4dq1A:
65.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6QYA_D_FOZD401_0
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		5 / 12 LEU A  59
LEU A 198
GLY A 228
PHE A 231
TYR A 264
 None
None
UMP  A 501 ( 4.0A)
None
UMP  A 501 (-4.2A)
 1.29A 6qyaD-4dq1A:
39.2		 6qyaD-4dq1A:
65.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6QYA_D_FOZD401_0
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		6 / 12 LEU A  59
LEU A 198
LEU A 227
GLY A 228
ASN A 232
TYR A 264
 None
None
None
UMP  A 501 ( 4.0A)
UMP  A 501 (-2.7A)
UMP  A 501 (-4.2A)
 0.53A 6qyaD-4dq1A:
39.2		 6qyaD-4dq1A:
65.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6R2E_A_FFOA403_0
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		5 / 12 ASP A 224
GLY A 228
PHE A 231
ASN A 232
TYR A 264
 None
UMP  A 501 ( 4.0A)
None
UMP  A 501 (-2.7A)
UMP  A 501 (-4.2A)
 0.96A 6r2eA-4dq1A:
34.3		 6r2eA-4dq1A:
43.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6R2E_A_FFOA403_0
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		5 / 12 ASP A 224
LEU A 227
GLY A 228
ASN A 232
TYR A 264
 None
None
UMP  A 501 ( 4.0A)
UMP  A 501 (-2.7A)
UMP  A 501 (-4.2A)
 0.33A 6r2eA-4dq1A:
34.3		 6r2eA-4dq1A:
43.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6R2E_E_FFOE403_0
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		5 / 12 TYR A 149
LEU A 198
LEU A 227
GLY A 228
ASN A 232
 None
None
None
UMP  A 501 ( 4.0A)
UMP  A 501 (-2.7A)
 0.80A 6r2eE-4dq1A:
34.1		 6r2eE-4dq1A:
43.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6R2E_H_FFOH403_0
(THYMIDYLATE SYNTHASE)		 4dq1 THYMIDYLATE SYNTHASE
(Staphylococcus
aureus) 		5 / 12 TYR A 149
ASP A 224
LEU A 227
GLY A 228
ASN A 232
 None
None
None
UMP  A 501 ( 4.0A)
UMP  A 501 (-2.7A)
 0.66A 6r2eH-4dq1A:
34.4		 6r2eH-4dq1A:
43.47