SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4dq7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2N_C_X2NC1479_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 4dq7 MEMBRANE PROTEIN
PHI6 P5
(Pseudomonas
virus
phi6) 		5 / 12 PHE A 103
PRO A  93
VAL A  98
ALA A  73
ALA A  75
 None
 1.22A 2x2nC-4dq7A:
undetectable		 2x2nC-4dq7A:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_B_TRPB1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 4dq7 MEMBRANE PROTEIN
PHI6 P5
(Pseudomonas
virus
phi6) 		4 / 8 GLY A 102
VAL A  99
ILE A  92
VAL A  70
 None
 0.81A 3fi0B-4dq7A:
undetectable		 3fi0B-4dq7A:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_E_TRPE1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 4dq7 MEMBRANE PROTEIN
PHI6 P5
(Pseudomonas
virus
phi6) 		4 / 7 GLY A 102
VAL A  99
ILE A  92
VAL A  70
 None
 0.79A 3fi0E-4dq7A:
undetectable		 3fi0E-4dq7A:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_G_TRPG1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 4dq7 MEMBRANE PROTEIN
PHI6 P5
(Pseudomonas
virus
phi6) 		4 / 8 GLY A 102
VAL A  99
ILE A  92
VAL A  70
 None
 0.79A 3fi0G-4dq7A:
undetectable		 3fi0G-4dq7A:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_Q_TRPQ1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 4dq7 MEMBRANE PROTEIN
PHI6 P5
(Pseudomonas
virus
phi6) 		4 / 8 GLY A 102
VAL A  99
ILE A  92
VAL A  70
 None
 0.79A 3fi0Q-4dq7A:
undetectable		 3fi0Q-4dq7A:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OAD_A_CLMA206_0
(GNAT SUPERFAMILY
ACETYLTRANSFERASE
PA4794)		 4dq7 MEMBRANE PROTEIN
PHI6 P5
(Pseudomonas
virus
phi6) 		4 / 4 ALA A 202
ALA A 205
ALA A 206
ALA A 209
 None
 0.12A 4oadA-4dq7A:
undetectable		 4oadA-4dq7A:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_B_ADNB501_2
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 4dq7 MEMBRANE PROTEIN
PHI6 P5
(Pseudomonas
virus
phi6) 		3 / 3 PRO A  53
LEU A  52
GLN A 199
 None
 0.70A 4pevB-4dq7A:
undetectable		 4pevB-4dq7A:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5N_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 4dq7 MEMBRANE PROTEIN
PHI6 P5
(Pseudomonas
virus
phi6) 		4 / 6 LEU A 176
ILE A 173
LEU A 189
GLU A 186
 None
 0.92A 4w5nA-4dq7A:
undetectable		 4w5nA-4dq7A:
13.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TDM_A_ADNA904_1
(ATP-CITRATE SYNTHASE)		 4dq7 MEMBRANE PROTEIN
PHI6 P5
(Pseudomonas
virus
phi6) 		4 / 4 THR A 121
ASP A 123
ARG A 127
LEU A 125
 None
 1.12A 5tdmA-4dq7A:
undetectable		 5tdmA-4dq7A:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TDZ_A_ADNA905_1
(ATP-CITRATE SYNTHASE)		 4dq7 MEMBRANE PROTEIN
PHI6 P5
(Pseudomonas
virus
phi6) 		4 / 6 THR A 121
ASP A 123
ARG A 127
LEU A 125
 None
 1.16A 5tdzA-4dq7A:
undetectable		 5tdzA-4dq7A:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NM4_A_SAMA402_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
PRDM9)		 4dq7 MEMBRANE PROTEIN
PHI6 P5
(Pseudomonas
virus
phi6) 		4 / 7 ALA A 182
GLY A 181
GLY A 124
ASN A 156
 None
 0.57A 6nm4A-4dq7A:
undetectable		 6nm4A-4dq7A:
21.95