SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4dqa'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDS_A_ESTA350_1
(17-BETA-HYDROXYSTERO
ID-DEHYDROGENASE)		 4dqa UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		5 / 12 LEU A 253
TYR A 265
TYR A 237
SER A 274
MET A 212
 None
 1.45A 1fdsA-4dqaA:
undetectable		 1fdsA-4dqaA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N2X_B_SAMB402_1
(S-ADENOSYL-METHYLTRA
NSFERASE MRAW)		 4dqa UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		4 / 5 VAL A 211
SER A 285
ASP A 279
GLN A 235
 None
 1.01A 1n2xB-4dqaA:
undetectable		 1n2xB-4dqaA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_G_FUAG708_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4dqa UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		5 / 11 THR A 365
PHE A 170
PHE A 304
LEU A 339
VAL A 313
 None
 1.40A 1q23G-4dqaA:
undetectable		 1q23G-4dqaA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GVC_B_MMZB501_1
(MONOOXYGENASE)		 4dqa UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		3 / 3 ASN A  42
TYR A  83
SER A 133
 None
 0.82A 2gvcB-4dqaA:
undetectable		 2gvcB-4dqaA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GVC_E_MMZE501_1
(MONOOXYGENASE)		 4dqa UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		3 / 3 ASN A  42
TYR A  83
SER A 133
 None
 0.80A 2gvcE-4dqaA:
undetectable		 2gvcE-4dqaA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA503_0
(CHORISMATE SYNTHASE)		 4dqa UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		4 / 5 GLN A 322
THR A 319
ARG A 318
ALA A 317
 None
 1.10A 2qhfA-4dqaA:
undetectable		 2qhfA-4dqaA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKP_C_478C200_2
(PROTEASE)		 4dqa UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		6 / 10 LEU A 193
GLY A 168
ASP A 197
VAL A 196
GLY A 292
ILE A 291
 None
 1.28A 3ekpD-4dqaA:
undetectable		 3ekpD-4dqaA:
14.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKT_B_017B200_1
(PROTEASE)		 4dqa UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		6 / 9 LEU A 193
GLY A 168
ASP A 197
VAL A 196
GLY A 292
ILE A 291
 None
 1.30A 3ektA-4dqaA:
undetectable		 3ektA-4dqaA:
14.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKT_D_017D200_1
(PROTEASE)		 4dqa UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		6 / 11 LEU A 193
GLY A 168
ASP A 197
VAL A 196
GLY A 292
ILE A 291
 None
 1.28A 3ektC-4dqaA:
undetectable		 3ektC-4dqaA:
14.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB153_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 4dqa UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		4 / 6 ILE A 361
THR A 208
PHE A 281
PHE A 185
 None
 1.22A 3elzB-4dqaA:
undetectable		 3elzB-4dqaA:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TPX_E_ACTE204_0
(E3 UBIQUITIN-PROTEIN
LIGASE MDM2)		 4dqa UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		3 / 3 LYS A 160
PRO A 161
LEU A 162
 None
 0.73A 3tpxE-4dqaA:
undetectable		 3tpxE-4dqaA:
13.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A3U_B_ACTB1358_0
(NADH:FLAVIN
OXIDOREDUCTASE/NADH
OXIDASE)		 4dqa UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		4 / 7 ILE A 278
GLN A 235
GLY A 234
VAL A 211
 None
 1.00A 4a3uB-4dqaA:
undetectable		 4a3uB-4dqaA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQC_A_017A101_2
(ASPARTYL PROTEASE)		 4dqa UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		5 / 9 LEU A 193
GLY A 168
VAL A 196
GLY A 292
ILE A 291
 None
 1.07A 4dqcB-4dqaA:
undetectable		 4dqcB-4dqaA:
13.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_B_NCTB501_1
(CYTOCHROME P450 2A6)		 4dqa UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		4 / 7 VAL A 177
PHE A 281
GLY A 207
PHE A 185
 None
 0.97A 4ejjB-4dqaA:
undetectable		 4ejjB-4dqaA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_H_ACTH614_0
(NADH DEHYDROGENASE,
PUTATIVE)		 4dqa UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		4 / 6 ILE A 108
VAL A 140
TYR A  35
VAL A  34
 None
 0.97A 5jwaH-4dqaA:
undetectable		 5jwaH-4dqaA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T2Z_B_017B201_2
(PROTEASE)		 4dqa UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		6 / 12 LEU A 193
GLY A 168
ASP A 197
VAL A 196
GLY A 292
ILE A 291
 None
 1.30A 5t2zB-4dqaA:
undetectable		 5t2zB-4dqaA:
13.43