SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4dqx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I9G_A_SAMA301_0
(HYPOTHETICAL PROTEIN
RV2118C)		 4dqx PROBABLE
OXIDOREDUCTASE
PROTEIN
(Rhizobium
etli) 		5 / 12 GLY A  34
GLY A  36
ALA A  42
ASP A  81
VAL A 131
 None
 1.01A 1i9gA-4dqxA:
7.1		 1i9gA-4dqxA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OPJ_A_STIA3_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 4dqx PROBABLE
OXIDOREDUCTASE
PROTEIN
(Rhizobium
etli) 		4 / 5 TYR A 161
LYS A 177
VAL A 106
ILE A 180
 None
 1.44A 1opjA-4dqxA:
0.5		 1opjA-4dqxA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UAY_A_ADNA1001_1
(TYPE II
3-HYDROXYACYL-COA
DEHYDROGENASE)		 4dqx PROBABLE
OXIDOREDUCTASE
PROTEIN
(Rhizobium
etli) 		7 / 11 GLY A  34
SER A  37
ASP A  58
ASP A  81
VAL A  82
ALA A 109
VAL A 131
 None
 0.41A 1uayA-4dqxA:
29.9		 1uayA-4dqxA:
29.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UAY_B_ADNB1002_1
(TYPE II
3-HYDROXYACYL-COA
DEHYDROGENASE)		 4dqx PROBABLE
OXIDOREDUCTASE
PROTEIN
(Rhizobium
etli) 		7 / 10 GLY A  34
SER A  37
ASP A  58
ASP A  81
VAL A  82
ALA A 109
VAL A 131
 None
 0.42A 1uayB-4dqxA:
30.5		 1uayB-4dqxA:
29.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_E_SAME301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 4dqx PROBABLE
OXIDOREDUCTASE
PROTEIN
(Rhizobium
etli) 		5 / 12 GLY A  34
ASP A  58
ASP A  81
ASN A 108
ALA A 109
 None
 0.98A 2bm9E-4dqxA:
5.4		 2bm9E-4dqxA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_2_BO221405_1
(PROTEASOME COMPONENT
PRE3)		 4dqx PROBABLE
OXIDOREDUCTASE
PROTEIN
(Rhizobium
etli) 		5 / 11 THR A  33
THR A 158
THR A 159
ALA A 200
GLY A 135
 None
 0.83A 2f162-4dqxA:
undetectable		 2f162-4dqxA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_N_BO2N1404_1
(PROTEASOME COMPONENT
PRE3)		 4dqx PROBABLE
OXIDOREDUCTASE
PROTEIN
(Rhizobium
etli) 		5 / 11 THR A  33
THR A 158
THR A 159
ALA A 200
GLY A 135
 None
 0.82A 2f16N-4dqxA:
undetectable		 2f16N-4dqxA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_A_SAMA1001_1
(SAM DEPENDENT
METHYLTRANSFERASE)		 4dqx PROBABLE
OXIDOREDUCTASE
PROTEIN
(Rhizobium
etli) 		3 / 3 ASP A  58
ASP A  62
ASP A  81
 None
 0.68A 2igtA-4dqxA:
8.0		 2igtA-4dqxA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_B_SAMB1002_1
(SAM DEPENDENT
METHYLTRANSFERASE)		 4dqx PROBABLE
OXIDOREDUCTASE
PROTEIN
(Rhizobium
etli) 		3 / 3 ASP A  58
ASP A  62
ASP A  81
 None
 0.69A 2igtB-4dqxA:
8.0		 2igtB-4dqxA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AY0_B_ADNB402_1
(UNCHARACTERIZED
PROTEIN MJ0883)		 4dqx PROBABLE
OXIDOREDUCTASE
PROTEIN
(Rhizobium
etli) 		5 / 10 GLY A  36
ASP A  58
ASN A  60
ASP A  81
VAL A  82
 None
 0.68A 3ay0B-4dqxA:
7.0		 3ay0B-4dqxA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DMF_A_SAMA388_0
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 4dqx PROBABLE
OXIDOREDUCTASE
PROTEIN
(Rhizobium
etli) 		5 / 12 GLY A  34
GLY A  36
ASP A  81
VAL A  82
VAL A 131
 None
 1.02A 3dmfA-4dqxA:
7.1		 3dmfA-4dqxA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_2_BO221405_1
(PROTEASOME COMPONENT
PRE3
PROTEASOME COMPONENT
PUP1)		 4dqx PROBABLE
OXIDOREDUCTASE
PROTEIN
(Rhizobium
etli) 		5 / 12 THR A  33
THR A 158
THR A 159
ALA A 200
GLY A 135
 None
 0.80A 3mg02-4dqxA:
undetectable
3mg0V-4dqxA:
undetectable		 3mg02-4dqxA:
21.91
3mg0V-4dqxA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_N_BO2N1404_1
(PROTEASOME COMPONENT
PRE3)		 4dqx PROBABLE
OXIDOREDUCTASE
PROTEIN
(Rhizobium
etli) 		5 / 11 THR A  33
THR A 158
THR A 159
ALA A 200
GLY A 135
 None
 0.80A 3mg0N-4dqxA:
undetectable		 3mg0N-4dqxA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_C_ACTC610_0
(GBAA_1210 PROTEIN)		 4dqx PROBABLE
OXIDOREDUCTASE
PROTEIN
(Rhizobium
etli) 		3 / 3 ASN A 199
ALA A 258
ARG A 197
 None
 0.79A 3tj7C-4dqxA:
undetectable
3tj7D-4dqxA:
undetectable		 3tj7C-4dqxA:
21.66
3tj7D-4dqxA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_B_ADNB353_2
(ADENOSINE KINASE)		 4dqx PROBABLE
OXIDOREDUCTASE
PROTEIN
(Rhizobium
etli) 		4 / 5 SER A 160
ILE A  39
TYR A 173
GLY A 204
 None
 1.00A 3uboB-4dqxA:
7.1		 3uboB-4dqxA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WZE_A_BAXA1201_2
(VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 2)		 4dqx PROBABLE
OXIDOREDUCTASE
PROTEIN
(Rhizobium
etli) 		5 / 8 VAL A  55
VAL A  54
ILE A  31
CYH A  30
ASP A 103
 None
 1.09A 3wzeA-4dqxA:
undetectable		 3wzeA-4dqxA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGH_A_SAMA401_0
(CAFFEIC ACID
O-METHYLTRANSFERASE)		 4dqx PROBABLE
OXIDOREDUCTASE
PROTEIN
(Rhizobium
etli) 		5 / 11 GLY A  34
GLY A  35
THR A  43
ASP A  58
ASP A  81
 None
 0.98A 4pghA-4dqxA:
6.7		 4pghA-4dqxA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4dqx PROBABLE
OXIDOREDUCTASE
PROTEIN
(Rhizobium
etli) 		5 / 12 THR A  33
THR A 158
THR A 159
ALA A 200
GLY A 135
 None
 0.86A 4qvnV-4dqxA:
undetectable
4qvnb-4dqxA:
undetectable		 4qvnV-4dqxA:
20.48
4qvnb-4dqxA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4dqx PROBABLE
OXIDOREDUCTASE
PROTEIN
(Rhizobium
etli) 		5 / 12 THR A  33
THR A 158
THR A 159
ALA A 200
GLY A 135
 None
 0.86A 4qvnH-4dqxA:
undetectable
4qvnN-4dqxA:
undetectable		 4qvnH-4dqxA:
20.48
4qvnN-4dqxA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_B_6V8B304_0
(PROTEASOME SUBUNIT
BETA TYPE-6
PROTEASOME SUBUNIT
BETA TYPE-7)		 4dqx PROBABLE
OXIDOREDUCTASE
PROTEIN
(Rhizobium
etli) 		5 / 12 THR A  33
THR A 158
THR A 159
ALA A 200
GLY A 135
 None
 0.95A 5lf7V-4dqxA:
undetectable
5lf7b-4dqxA:
undetectable		 5lf7V-4dqxA:
20.85
5lf7b-4dqxA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_N_6V8N305_0
(PROTEASOME SUBUNIT
BETA TYPE-6
PROTEASOME SUBUNIT
BETA TYPE-7)		 4dqx PROBABLE
OXIDOREDUCTASE
PROTEIN
(Rhizobium
etli) 		5 / 12 THR A  33
THR A 158
THR A 159
ALA A 200
GLY A 135
 None
 0.92A 5lf7H-4dqxA:
undetectable
5lf7N-4dqxA:
undetectable		 5lf7H-4dqxA:
20.85
5lf7N-4dqxA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LW1_E_ADNE401_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 8)		 4dqx PROBABLE
OXIDOREDUCTASE
PROTEIN
(Rhizobium
etli) 		6 / 10 GLY A 135
VAL A  82
ALA A  88
ILE A  31
MET A  91
LEU A 105
 None
 1.46A 5lw1E-4dqxA:
undetectable		 5lw1E-4dqxA:
16.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_D_SAMD501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 4dqx PROBABLE
OXIDOREDUCTASE
PROTEIN
(Rhizobium
etli) 		6 / 10 ARG A  66
ILE A  39
GLY A  40
GLU A  45
GLY A  36
ALA A 240
 None
 0.95A 5o96C-4dqxA:
2.6
5o96D-4dqxA:
2.4		 5o96C-4dqxA:
20.77
5o96D-4dqxA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_D_SAMD501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 4dqx PROBABLE
OXIDOREDUCTASE
PROTEIN
(Rhizobium
etli) 		5 / 10 ILE A  39
GLY A  40
GLU A  45
GLY A  35
ALA A 240
 None
 1.08A 5o96C-4dqxA:
2.6
5o96D-4dqxA:
2.4		 5o96C-4dqxA:
20.77
5o96D-4dqxA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WY0_A_SAMA800_0
(SMALL RNA
2'-O-METHYLTRANSFERA
SE)		 4dqx PROBABLE
OXIDOREDUCTASE
PROTEIN
(Rhizobium
etli) 		5 / 12 GLY A  34
GLY A  36
ASP A  58
ASN A  60
ILE A  39
 None
 0.58A 5wy0A-4dqxA:
6.5		 5wy0A-4dqxA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WY0_A_SAMA800_0
(SMALL RNA
2'-O-METHYLTRANSFERA
SE)		 4dqx PROBABLE
OXIDOREDUCTASE
PROTEIN
(Rhizobium
etli) 		5 / 12 GLY A  34
GLY A  36
ASP A  58
ASN A  60
VAL A  82
 None
 0.66A 5wy0A-4dqxA:
6.5		 5wy0A-4dqxA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZW4_A_SAMA302_0
(PUTATIVE
O-METHYLTRANSFERASE
YRRM)		 4dqx PROBABLE
OXIDOREDUCTASE
PROTEIN
(Rhizobium
etli) 		5 / 12 ILE A  71
GLY A  35
ALA A  44
ALA A 109
ALA A  57
 None
 1.01A 5zw4A-4dqxA:
9.4		 5zw4A-4dqxA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B3A_A_SAMA701_0
(APRA
METHYLTRANSFERASE 1)		 4dqx PROBABLE
OXIDOREDUCTASE
PROTEIN
(Rhizobium
etli) 		5 / 12 GLY A  34
GLY A  36
ASN A  60
ALA A  63
ASP A  81
 None
 0.91A 6b3aA-4dqxA:
3.7		 6b3aA-4dqxA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B3B_A_SAMA701_0
(APRA
METHYLTRANSFERASE 1)		 4dqx PROBABLE
OXIDOREDUCTASE
PROTEIN
(Rhizobium
etli) 		5 / 12 GLY A  34
GLY A  36
ASN A  60
ALA A  63
ASP A  81
 None
 0.90A 6b3bA-4dqxA:
4.4		 6b3bA-4dqxA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GSD_A_STRA401_0
(PROGESTERONE
5-BETA-REDUCTASE)		 4dqx PROBABLE
OXIDOREDUCTASE
PROTEIN
(Rhizobium
etli) 		5 / 12 VAL A 143
ILE A 144
ASN A 157
VAL A 198
ILE A 196
 None
 1.35A 6gsdA-4dqxA:
18.2		 6gsdA-4dqxA:
13.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_B_BO2B201_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-2)		 4dqx PROBABLE
OXIDOREDUCTASE
PROTEIN
(Rhizobium
etli) 		5 / 12 THR A  33
THR A 158
THR A 159
ALA A 200
GLY A 135
 None
 0.85A 6hwdV-4dqxA:
undetectable
6hwdb-4dqxA:
undetectable		 6hwdV-4dqxA:
14.45
6hwdb-4dqxA:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_N_BO2N201_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-2)		 4dqx PROBABLE
OXIDOREDUCTASE
PROTEIN
(Rhizobium
etli) 		5 / 12 THR A  33
THR A 158
THR A 159
ALA A 200
GLY A 135
 None
 0.86A 6hwdH-4dqxA:
undetectable
6hwdN-4dqxA:
undetectable		 6hwdH-4dqxA:
14.45
6hwdN-4dqxA:
17.79