SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4dr9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_X_BRLX504_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 4dr9 PEPTIDE DEFORMYLASE
(Synechococcus
elongatus) 		5 / 12 ILE A  60
GLY A  61
LEU A 139
LEU A  90
TYR A 129
 BB2  A 203 (-4.1A)
BB2  A 203 (-4.4A)
None
None
None
 1.47A 1fm6X-4dr9A:
undetectable		 1fm6X-4dr9A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4L_A_TPVA403_1
(PROTEASE)		 4dr9 PEPTIDE DEFORMYLASE
(Synechococcus
elongatus) 		5 / 12 LEU A  51
ASP A  41
ILE A  39
VAL A  75
ILE A  47
 None
 1.25A 2o4lA-4dr9A:
undetectable		 2o4lA-4dr9A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5P_B_MK1B902_1
(PROTEASE)		 4dr9 PEPTIDE DEFORMYLASE
(Synechococcus
elongatus) 		5 / 12 LEU A  51
ILE A  39
GLY A 134
VAL A  75
ILE A  47
 None
 1.07A 2r5pA-4dr9A:
undetectable		 2r5pA-4dr9A:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEC_B_HAEB271_1
(COLLAGENASE 3)		 4dr9 PEPTIDE DEFORMYLASE
(Synechococcus
elongatus) 		3 / 3 HIS A 151
GLU A 152
HIS A 155
 ZN  A 201 ( 3.3A)
BB2  A 203 (-2.6A)
ZN  A 201 ( 3.3A)
 0.14A 3kecB-4dr9A:
undetectable		 3kecB-4dr9A:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXX_A_DR7A100_2
(HIV-1 PROTEASE)		 4dr9 PEPTIDE DEFORMYLASE
(Synechococcus
elongatus) 		5 / 11 LEU A  51
ASP A  41
ILE A  39
VAL A  75
ILE A  47
 None
 1.18A 3oxxB-4dr9A:
undetectable		 3oxxB-4dr9A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYZ_A_CCSA109_0
(CELLULOSOME-RELATED
PROTEIN MODULE FROM
RUMINOCOCCUS
FLAVEFACIENS THAT
RESEMBLES
PAPAIN-LIKE CYSTEINE
PEPTIDASES)		 4dr9 PEPTIDE DEFORMYLASE
(Synechococcus
elongatus) 		4 / 8 PHE A 161
VAL A 162
HIS A 155
ALA A  63
 None
None
ZN  A 201 ( 3.3A)
None
 1.02A 4eyzA-4dr9A:
undetectable		 4eyzA-4dr9A:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DNU_A_BEZA319_0
(SHKAI2IB)		 4dr9 PEPTIDE DEFORMYLASE
(Synechococcus
elongatus) 		4 / 5 GLN A 150
HIS A 151
ILE A 149
ILE A  74
 None
ZN  A 201 ( 3.3A)
None
None
 1.16A 5dnuA-4dr9A:
undetectable		 5dnuA-4dr9A:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DNV_A_BEZA304_0
(SHKAI2IB)		 4dr9 PEPTIDE DEFORMYLASE
(Synechococcus
elongatus) 		4 / 5 GLN A 150
HIS A 151
ILE A 149
ILE A  74
 None
ZN  A 201 ( 3.3A)
None
None
 1.09A 5dnvA-4dr9A:
undetectable		 5dnvA-4dr9A:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA310_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 4dr9 PEPTIDE DEFORMYLASE
(Synechococcus
elongatus) 		3 / 3 GLU A 152
HIS A 151
ARG A 147
 BB2  A 203 (-2.6A)
ZN  A 201 ( 3.3A)
None
 0.95A 5uunA-4dr9A:
undetectable		 5uunA-4dr9A:
21.94