SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4dry'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZM_A_BZMA600_0
(ODORANT-BINDING
PROTEIN)		 4dry 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Sinorhizobium
meliloti) 		4 / 8 ILE A 186
MET A 134
ASN A  94
GLY A 143
 None
 0.93A 1dzmA-4dryA:
undetectable		 1dzmA-4dryA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W0G_A_MYTA1499_1
(CYTOCHROME P450 3A4)		 4dry 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Sinorhizobium
meliloti) 		4 / 6 ARG A  57
ILE A 223
ALA A 227
ALA A  32
 None
 0.99A 1w0gA-4dryA:
undetectable		 1w0gA-4dryA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VH3_B_DAHB2_1
(RANASMURFIN)		 4dry 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Sinorhizobium
meliloti) 		4 / 8 ALA A 165
ALA A 169
GLY A 149
ALA A 153
 None
 0.80A 2vh3B-4dryA:
undetectable		 2vh3B-4dryA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_B_QPSB1060_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 4dry 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Sinorhizobium
meliloti) 		5 / 10 THR A 246
SER A 160
GLY A 149
ALA A 153
GLN A 154
 None
 1.34A 2x2iB-4dryA:
undetectable		 2x2iB-4dryA:
14.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GCS_A_BAXA401_2
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)		 4dry 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Sinorhizobium
meliloti) 		4 / 6 VAL A  93
LEU A 126
ILE A 226
ILE A 146
 None
 0.96A 3gcsA-4dryA:
undetectable		 3gcsA-4dryA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILT_H_TRUH800_1
(GLUTAMATE RECEPTOR 2)		 4dry 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Sinorhizobium
meliloti) 		3 / 3 ILE A  39
SER A  31
SER A  36
 None
 0.57A 3iltH-4dryA:
undetectable		 3iltH-4dryA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OHT_A_1N1A2000_1
(P38A)		 4dry 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Sinorhizobium
meliloti) 		5 / 12 ILE A 151
ASN A 148
VAL A  93
ARG A 144
ALA A 196
 None
 1.24A 3ohtA-4dryA:
undetectable
3ohtB-4dryA:
undetectable		 3ohtA-4dryA:
22.84
3ohtB-4dryA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OWX_A_XRAA233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 4dry 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Sinorhizobium
meliloti) 		5 / 9 GLY A  19
GLY A  18
VAL A  93
ASN A  95
ILE A  54
 None
 1.44A 3owxA-4dryA:
4.3		 3owxA-4dryA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQ6_B_ADNB401_2
(ADENOSINE KINASE,
PUTATIVE)		 4dry 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Sinorhizobium
meliloti) 		4 / 5 LEU A 126
GLY A 123
PHE A  79
ASN A 147
 None
 1.32A 3uq6B-4dryA:
5.9		 3uq6B-4dryA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1G_B_LNLB701_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4dry 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Sinorhizobium
meliloti) 		4 / 7 VAL A  69
VAL A  75
ASN A 147
MET A 134
 None
 1.12A 4e1gB-4dryA:
undetectable		 4e1gB-4dryA:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_D_CLQD303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 4dry 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Sinorhizobium
meliloti) 		4 / 6 GLY A  19
GLY A  18
ASN A  95
ILE A  54
 None
 0.84A 4fglD-4dryA:
5.4		 4fglD-4dryA:
21.00