SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ds1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UYU_B_CAMB1416_0
(CYTOCHROME P450-CAM)		 4ds1 DYNEIN LIGHT CHAIN
1, CYTOPLASMIC
(Saccharomyces
cerevisiae) 		4 / 8 PHE A  79
LEU A  32
THR A  44
VAL A  59
 None
 1.06A 1uyuB-4ds1A:
undetectable		 1uyuB-4ds1A:
12.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZAX_A_CAMA422_0
(CYTOCHROME P450-CAM)		 4ds1 DYNEIN LIGHT CHAIN
1, CYTOPLASMIC
(Saccharomyces
cerevisiae) 		4 / 7 PHE A  79
LEU A  32
THR A  44
VAL A  59
 None
 1.02A 2zaxA-4ds1A:
undetectable		 2zaxA-4ds1A:
12.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWG_B_CAMB420_0
(CAMPHOR
5-MONOOXYGENASE)		 4ds1 DYNEIN LIGHT CHAIN
1, CYTOPLASMIC
(Saccharomyces
cerevisiae) 		4 / 7 PHE A  79
LEU A  32
THR A  44
VAL A  59
 None
 1.04A 3fwgB-4ds1A:
undetectable		 3fwgB-4ds1A:
12.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWI_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 4ds1 DYNEIN LIGHT CHAIN
1, CYTOPLASMIC
(Saccharomyces
cerevisiae) 		4 / 7 PHE A  79
LEU A  32
THR A  44
VAL A  59
 None
 1.00A 3fwiA-4ds1A:
undetectable		 3fwiA-4ds1A:
12.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HBB_A_TMQA611_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 4ds1 DYNEIN LIGHT CHAIN
1, CYTOPLASMIC
(Saccharomyces
cerevisiae) 		5 / 10 ILE A  24
ILE A  81
PRO A   9
LEU A  32
ILE A  41
 None
 1.09A 3hbbA-4ds1A:
undetectable		 3hbbA-4ds1A:
11.54