SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4dsq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQH_B_FLPB1701_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 4dsq PEROXIREDOXIN TYPE-2
(Saccharomyces
cerevisiae) 		5 / 12 VAL A 106
VAL A  86
ILE A  67
GLY A  69
LEU A  74
 None
 1.02A 1eqhB-4dsqA:
undetectable		 1eqhB-4dsqA:
14.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AFT_D_QMRD301_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 4dsq PEROXIREDOXIN TYPE-2
(Saccharomyces
cerevisiae) 		4 / 8 TYR A  70
VAL A 145
VAL A 151
ILE A  51
 None
 1.10A 4aftD-4dsqA:
undetectable
4aftE-4dsqA:
undetectable		 4aftD-4dsqA:
22.81
4aftE-4dsqA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AX8_A_SAMA1474_0
(WBDD)		 4dsq PEROXIREDOXIN TYPE-2
(Saccharomyces
cerevisiae) 		5 / 12 ILE A  51
ILE A  50
SER A 171
VAL A 172
HIS A 175
 None
 1.00A 4ax8A-4dsqA:
undetectable		 4ax8A-4dsqA:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZV_A_SAMA1474_0
(WBDD)		 4dsq PEROXIREDOXIN TYPE-2
(Saccharomyces
cerevisiae) 		5 / 12 ILE A  51
ILE A  50
SER A 171
VAL A 172
HIS A 175
 None
 0.97A 4azvA-4dsqA:
undetectable		 4azvA-4dsqA:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYS_A_ACTA402_0
(MCCC FAMILY PROTEIN)		 4dsq PEROXIREDOXIN TYPE-2
(Saccharomyces
cerevisiae) 		4 / 6 SER A  30
ASP A  25
SER A  28
ASP A  27
 None
 1.26A 4eysA-4dsqA:
undetectable		 4eysA-4dsqA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IK7_A_IMNA201_1
(TRANSTHYRETIN)		 4dsq PEROXIREDOXIN TYPE-2
(Saccharomyces
cerevisiae) 		4 / 7 THR A  52
ALA A  54
THR A  90
VAL A  88
 None
 0.69A 4ik7A-4dsqA:
undetectable		 4ik7A-4dsqA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IK7_B_IMNB201_1
(TRANSTHYRETIN)		 4dsq PEROXIREDOXIN TYPE-2
(Saccharomyces
cerevisiae) 		4 / 8 THR A  52
ALA A  54
THR A  90
VAL A  88
 None
 0.63A 4ik7B-4dsqA:
undetectable		 4ik7B-4dsqA:
20.11