SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4dt4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA152_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 4dt4 FKBP-TYPE 16 KDA
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Escherichia
coli) 		3 / 3 VAL A  57
LYS A  56
HIS A   0
 None
 0.96A 3elzA-4dt4A:
undetectable		 3elzA-4dt4A:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KKZ_A_SAMA301_0
(UNCHARACTERIZED
PROTEIN Q5LES9)		 4dt4 FKBP-TYPE 16 KDA
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Escherichia
coli) 		5 / 12 GLN A 132
GLY A  72
GLY A 131
GLU A  66
ALA A  70
 None
 1.11A 3kkzA-4dt4A:
undetectable		 3kkzA-4dt4A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SXJ_A_SAMA258_0
(PUTATIVE
METHYLTRANSFERASE)		 4dt4 FKBP-TYPE 16 KDA
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Escherichia
coli) 		5 / 12 GLN A 132
GLY A  72
GLY A 131
GLU A  66
ALA A  70
 None
 1.12A 3sxjA-4dt4A:
undetectable		 3sxjA-4dt4A:
26.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SXJ_B_SAMB258_0
(PUTATIVE
METHYLTRANSFERASE)		 4dt4 FKBP-TYPE 16 KDA
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Escherichia
coli) 		5 / 12 GLN A 132
GLY A  72
GLY A 131
GLU A  66
ALA A  70
 None
 1.11A 3sxjB-4dt4A:
undetectable		 3sxjB-4dt4A:
26.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7S_B_SAMB300_0
(PUTATIVE
METHYLTRANSFERASE)		 4dt4 FKBP-TYPE 16 KDA
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Escherichia
coli) 		5 / 12 GLN A 132
GLY A  72
GLY A 131
GLU A  66
ALA A  70
 None
 1.10A 3t7sB-4dt4A:
undetectable		 3t7sB-4dt4A:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7S_D_SAMD300_0
(PUTATIVE
METHYLTRANSFERASE)		 4dt4 FKBP-TYPE 16 KDA
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Escherichia
coli) 		5 / 12 GLN A 132
GLY A  72
GLY A 131
GLU A  66
ALA A  70
 None
 1.09A 3t7sD-4dt4A:
undetectable		 3t7sD-4dt4A:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_A_FK5A205_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 4dt4 FKBP-TYPE 16 KDA
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Escherichia
coli) 		5 / 10 LEU A  17
LEU A  44
LEU A  48
LEU A 129
PHE A 136
 None
 0.97A 4odoA-4dt4A:
15.1		 4odoA-4dt4A:
26.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_B_FK5B203_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 4dt4 FKBP-TYPE 16 KDA
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Escherichia
coli) 		5 / 10 LEU A  17
LEU A  44
LEU A  48
LEU A 129
PHE A 136
 None
 0.99A 4odoB-4dt4A:
12.0		 4odoB-4dt4A:
26.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_C_FK5C204_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 4dt4 FKBP-TYPE 16 KDA
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Escherichia
coli) 		5 / 10 LEU A  17
LEU A  44
LEU A  48
LEU A 129
PHE A 136
 None
 0.95A 4odoC-4dt4A:
12.1		 4odoC-4dt4A:
26.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WWS_B_SAMB501_0
(PUTATIVE
METHYLTRANSFERASE
NSUN6)		 4dt4 FKBP-TYPE 16 KDA
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Escherichia
coli) 		5 / 12 PRO A  74
GLY A 131
ASP A 124
ILE A  79
GLY A  96
 None
 1.23A 5wwsB-4dt4A:
undetectable		 5wwsB-4dt4A:
15.82