SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4dup'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NV4_A_ACTA148_0
(UPF0066 PROTEIN
AF_0241)		 4dup QUINONE
OXIDOREDUCTASE
(Rhizobium
etli) 		3 / 3 VAL A  38
GLU A  41
GLU A  74
 None
 0.69A 2nv4A-4dupA:
undetectable		 2nv4A-4dupA:
17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA507_0
(CHORISMATE SYNTHASE)		 4dup QUINONE
OXIDOREDUCTASE
(Rhizobium
etli) 		3 / 3 LEU A  69
ASN A  96
ARG A 271
 None
 0.93A 2qhfA-4dupA:
undetectable		 2qhfA-4dupA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ID6_C_SAMC301_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 4dup QUINONE
OXIDOREDUCTASE
(Rhizobium
etli) 		5 / 12 GLY A 237
ALA A 234
SER A 148
ALA A 141
ASP A 236
 None
 1.20A 3id6C-4dupA:
7.0		 3id6C-4dupA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPS_A_CHDA211_0
(CMER)		 4dup QUINONE
OXIDOREDUCTASE
(Rhizobium
etli) 		5 / 10 LEU A 143
ALA A 168
PHE A 169
GLY A 170
CYH A 186
 None
 1.20A 3qpsA-4dupA:
undetectable		 3qpsA-4dupA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1477_0
(MJ0495-LIKE PROTEIN)		 4dup QUINONE
OXIDOREDUCTASE
(Rhizobium
etli) 		4 / 6 THR A 155
GLY A 159
ILE A 151
LEU A 189
 None
 1.12A 4ac9C-4dupA:
2.2		 4ac9C-4dupA:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1477_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 4dup QUINONE
OXIDOREDUCTASE
(Rhizobium
etli) 		4 / 6 THR A 155
GLY A 159
ILE A 151
LEU A 189
 None
 1.13A 4acaC-4dupA:
2.2		 4acaC-4dupA:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_A_ADNA401_2
(ADENOSINE KINASE)		 4dup QUINONE
OXIDOREDUCTASE
(Rhizobium
etli) 		4 / 4 LEU A 245
ILE A 241
GLY A 246
PHE A 244
 None
 1.01A 4dc3A-4dupA:
2.7		 4dc3A-4dupA:
25.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FJP_A_NPSA711_1
(LACTOTRANSFERRIN)		 4dup QUINONE
OXIDOREDUCTASE
(Rhizobium
etli) 		4 / 6 THR A 176
GLY A 153
TYR A 225
GLY A 222
 None
 0.90A 4fjpA-4dupA:
undetectable		 4fjpA-4dupA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYN_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 2)		 4dup QUINONE
OXIDOREDUCTASE
(Rhizobium
etli) 		5 / 12 PHE A 138
ILE A 216
THR A 161
LEU A 218
LEU A 285
 None
 1.34A 4qynA-4dupA:
undetectable		 4qynA-4dupA:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_K_6V8K305_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-5)		 4dup QUINONE
OXIDOREDUCTASE
(Rhizobium
etli) 		5 / 11 ALA A 175
THR A 176
ALA A 177
VAL A 173
GLY A 159
 None
 0.88A 5lf7K-4dupA:
undetectable
5lf7L-4dupA:
undetectable		 5lf7K-4dupA:
21.83
5lf7L-4dupA:
24.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_Y_6V8Y306_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-5)		 4dup QUINONE
OXIDOREDUCTASE
(Rhizobium
etli) 		5 / 11 ALA A 175
THR A 176
ALA A 177
VAL A 173
GLY A 159
 None
 0.89A 5lf7Y-4dupA:
undetectable
5lf7Z-4dupA:
undetectable		 5lf7Y-4dupA:
21.83
5lf7Z-4dupA:
24.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0O_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 4dup QUINONE
OXIDOREDUCTASE
(Rhizobium
etli) 		5 / 12 ILE A 163
GLY A 159
ALA A 175
ALA A 191
VAL A 149
 None
 1.11A 5n0oB-4dupA:
undetectable		 5n0oB-4dupA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNF_C_QPSC602_2
(-)		 4dup QUINONE
OXIDOREDUCTASE
(Rhizobium
etli) 		5 / 12 ASP A  62
ASN A  96
GLU A 128
PRO A 107
GLY A 109
 None
 1.30A 6gnfC-4dupA:
3.7		 6gnfC-4dupA:
22.83