SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4dut'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACL_C_REAC503_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4dut NUCLEOSIDE
DIPHOSPHATE KINASE
(Burkholderia
thailandensis) 		6 / 10 ILE A  23
ALA A 115
ALA A  14
ASN A  18
PHE A 107
ALA A 108
 None
 1.39A 2aclC-4dutA:
undetectable		 2aclC-4dutA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DRD_A_MIYA2001_1
(ACRB)		 4dut NUCLEOSIDE
DIPHOSPHATE KINASE
(Burkholderia
thailandensis) 		5 / 9 GLN A  22
PHE A 107
ILE A  10
ALA A 115
VAL A 116
 None
 1.40A 2drdA-4dutA:
4.0		 2drdA-4dutA:
8.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GV1_B_BEZB303_0
(DISULFIDE
INTERCHANGE PROTEIN)		 4dut NUCLEOSIDE
DIPHOSPHATE KINASE
(Burkholderia
thailandensis) 		4 / 4 LEU A   7
ALA A  36
VAL A 138
PRO A 134
 None
 1.22A 3gv1B-4dutA:
undetectable		 3gv1B-4dutA:
25.77