SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4duu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1B2I_A_AMHA84_1
(PROTEIN
(PLASMINOGEN))
4duu PLASMINOGEN
(Homo
sapiens)
4 / 7 TRP A 417
PHE A 419
ARG A 426
TRP A 427
None
1.11A 1b2iA-4duuA:
10.9
1b2iA-4duuA:
61.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1B2I_A_AMHA84_1
(PROTEIN
(PLASMINOGEN))
4duu PLASMINOGEN
(Homo
sapiens)
6 / 7 TYR A 200
ASP A 219
GLU A 221
TRP A 225
PHE A 227
TRP A 235
None
0.69A 1b2iA-4duuA:
10.9
1b2iA-4duuA:
61.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1B2I_A_AMHA84_1
(PROTEIN
(PLASMINOGEN))
4duu PLASMINOGEN
(Homo
sapiens)
6 / 7 TYR A 200
GLU A 221
TRP A 225
PHE A 227
ARG A 234
TRP A 235
None
0.79A 1b2iA-4duuA:
10.9
1b2iA-4duuA:
61.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CEA_A_ACAA90_1
(PLASMINOGEN)
4duu PLASMINOGEN
(Homo
sapiens)
5 / 8 ASP A 137
ASP A 139
TRP A 144
TYR A 146
TYR A 154
None
0.71A 1ceaA-4duuA:
undetectable
1ceaB-4duuA:
15.2
1ceaA-4duuA:
100.00
1ceaB-4duuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CEA_A_ACAA90_1
(PLASMINOGEN)
4duu PLASMINOGEN
(Homo
sapiens)
5 / 8 ASP A 516
ASP A 518
TRP A 523
TYR A 525
TYR A 533
None
0.71A 1ceaA-4duuA:
undetectable
1ceaB-4duuA:
15.2
1ceaA-4duuA:
100.00
1ceaB-4duuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CEA_B_ACAB90_1
(PLASMINOGEN)
4duu PLASMINOGEN
(Homo
sapiens)
5 / 7 ASP A 137
ASP A 139
TRP A 144
TYR A 146
TYR A 154
None
0.64A 1ceaB-4duuA:
15.2
1ceaB-4duuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CEA_B_ACAB90_1
(PLASMINOGEN)
4duu PLASMINOGEN
(Homo
sapiens)
5 / 7 ASP A 516
ASP A 518
TRP A 523
TYR A 525
TYR A 533
None
0.61A 1ceaB-4duuA:
15.2
1ceaB-4duuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CEB_A_AMHA90_1
(PLASMINOGEN)
4duu PLASMINOGEN
(Homo
sapiens)
6 / 7 ASP A 137
ASP A 139
TRP A 144
TYR A 146
ARG A 153
TYR A 154
None
0.83A 1cebA-4duuA:
15.1
1cebA-4duuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CEB_A_AMHA90_1
(PLASMINOGEN)
4duu PLASMINOGEN
(Homo
sapiens)
4 / 7 ASP A 516
ASP A 518
TRP A 523
TYR A 525
None
0.78A 1cebA-4duuA:
15.1
1cebA-4duuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CEB_A_AMHA90_1
(PLASMINOGEN)
4duu PLASMINOGEN
(Homo
sapiens)
4 / 7 ASP A 516
TRP A 523
TYR A 525
TYR A 533
None
0.64A 1cebA-4duuA:
15.1
1cebA-4duuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CEB_B_AMHB90_1
(PLASMINOGEN)
4duu PLASMINOGEN
(Homo
sapiens)
6 / 7 ASP A 137
ASP A 139
TRP A 144
TYR A 146
ARG A 153
TYR A 154
None
0.82A 1cebB-4duuA:
15.3
1cebB-4duuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CEB_B_AMHB90_1
(PLASMINOGEN)
4duu PLASMINOGEN
(Homo
sapiens)
5 / 7 ASP A 516
ASP A 518
TRP A 523
TYR A 525
TYR A 533
None
0.74A 1cebB-4duuA:
15.3
1cebB-4duuA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D8C_A_SORA4000_0
(MALATE SYNTHASE G)
4duu PLASMINOGEN
(Homo
sapiens)
3 / 3 GLN A 484
HIS A 492
PRO A 529
None
0.89A 1d8cA-4duuA:
undetectable
1d8cA-4duuA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_2
(HIV-1 PROTEASE)
4duu PLASMINOGEN
(Homo
sapiens)
3 / 3 ARG A 776
THR A 678
VAL A 674
None
0.92A 1hxbA-4duuA:
undetectable
1hxbA-4duuA:
7.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG3_A_ADNA500_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)
4duu PLASMINOGEN
(Homo
sapiens)
5 / 11 GLY A 757
ILE A 682
LEU A 745
ASP A 740
GLY A 589
None
1.12A 1jg3A-4duuA:
undetectable
1jg3A-4duuA:
14.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG3_B_ADNB550_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)
4duu PLASMINOGEN
(Homo
sapiens)
5 / 11 GLY A 757
ILE A 682
LEU A 745
ASP A 740
GLY A 589
None
1.09A 1jg3B-4duuA:
undetectable
1jg3B-4duuA:
14.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK2_A_ACAA91_1
(TISSUE-TYPE
PLASMINOGEN
ACTIVATOR)
4duu PLASMINOGEN
(Homo
sapiens)
4 / 8 TYR A 200
ASP A 219
TRP A 225
TRP A 235
None
1.05A 1pk2A-4duuA:
8.3
1pk2A-4duuA:
9.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_A_CTXA1_1
(CES1 PROTEIN)
4duu PLASMINOGEN
(Homo
sapiens)
5 / 12 ALA A 648
GLY A 742
GLY A 589
LEU A 599
LEU A 618
None
1.00A 1ya4A-4duuA:
undetectable
1ya4A-4duuA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YDB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)
4duu PLASMINOGEN
(Homo
sapiens)
5 / 11 GLN A  52
HIS A 494
PHE A 497
THR A 498
THR A 501
None
1.20A 1ydbA-4duuA:
undetectable
1ydbA-4duuA:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A8T_B_ADNB252_1
(U8 SNORNA-BINDING
PROTEIN X29)
4duu PLASMINOGEN
(Homo
sapiens)
4 / 8 GLY A 739
THR A 591
ILE A 682
GLN A 576
None
0.70A 2a8tB-4duuA:
undetectable
2a8tB-4duuA:
13.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_C_SAMC301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)
4duu PLASMINOGEN
(Homo
sapiens)
6 / 12 LEU A 745
GLY A 742
TYR A 774
CYH A 604
ALA A 601
ALA A 602
None
1.39A 2br4C-4duuA:
undetectable
2br4C-4duuA:
13.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_D_SAMD301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)
4duu PLASMINOGEN
(Homo
sapiens)
6 / 12 LEU A 745
GLY A 742
TYR A 774
CYH A 604
ALA A 601
ALA A 602
None
1.43A 2br4D-4duuA:
undetectable
2br4D-4duuA:
13.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PK4_A_ACAA100_1
(HUMAN PLASMINOGEN
KRINGLE 4)
4duu PLASMINOGEN
(Homo
sapiens)
4 / 7 ASP A 137
ASP A 139
TRP A 144
ARG A 153
None
0.90A 2pk4A-4duuA:
14.0
2pk4A-4duuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PK4_A_ACAA100_1
(HUMAN PLASMINOGEN
KRINGLE 4)
4duu PLASMINOGEN
(Homo
sapiens)
4 / 7 ASP A 219
TRP A 225
PHE A 227
ARG A 234
None
1.00A 2pk4A-4duuA:
14.0
2pk4A-4duuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PK4_A_ACAA100_1
(HUMAN PLASMINOGEN
KRINGLE 4)
4duu PLASMINOGEN
(Homo
sapiens)
4 / 7 ASP A 219
TRP A 225
PHE A 227
TRP A 235
None
0.69A 2pk4A-4duuA:
14.0
2pk4A-4duuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PK4_A_ACAA100_1
(HUMAN PLASMINOGEN
KRINGLE 4)
4duu PLASMINOGEN
(Homo
sapiens)
5 / 7 LYS A 392
ASP A 411
TRP A 417
PHE A 419
ARG A 426
None
0.99A 2pk4A-4duuA:
14.0
2pk4A-4duuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PK4_A_ACAA100_1
(HUMAN PLASMINOGEN
KRINGLE 4)
4duu PLASMINOGEN
(Homo
sapiens)
6 / 7 LYS A 392
ASP A 413
TRP A 417
PHE A 419
ARG A 426
TRP A 427
None
0.84A 2pk4A-4duuA:
14.0
2pk4A-4duuA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_2
(PROTEASE RETROPEPSIN)
4duu PLASMINOGEN
(Homo
sapiens)
3 / 3 ARG A 776
THR A 678
VAL A 674
None
0.99A 2qakA-4duuA:
undetectable
2qakA-4duuA:
8.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VZV_A_GCSA1900_1
(EXO-BETA-D-GLUCOSAMI
NIDASE)
4duu PLASMINOGEN
(Homo
sapiens)
4 / 6 CYH A  34
GLU A  35
ASP A  37
TYR A  80
None
1.25A 2vzvA-4duuA:
0.0
2vzvA-4duuA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_B_ADNB438_2
(ADENOSYLHOMOCYSTEINA
SE)
4duu PLASMINOGEN
(Homo
sapiens)
3 / 3 THR A 369
GLU A 554
HIS A 569
None
0.64A 3g1uB-4duuA:
undetectable
3g1uB-4duuA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KIV_A_ACAA100_1
(APOLIPOPROTEIN)
4duu PLASMINOGEN
(Homo
sapiens)
4 / 7 ASP A 137
ASP A 139
TRP A 144
ARG A 153
None
0.88A 3kivA-4duuA:
14.4
3kivA-4duuA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KIV_A_ACAA100_1
(APOLIPOPROTEIN)
4duu PLASMINOGEN
(Homo
sapiens)
5 / 7 ASP A 219
TRP A 225
PHE A 227
ARG A 234
TRP A 235
None
0.90A 3kivA-4duuA:
14.4
3kivA-4duuA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KIV_A_ACAA100_1
(APOLIPOPROTEIN)
4duu PLASMINOGEN
(Homo
sapiens)
5 / 7 ASP A 413
TRP A 417
PHE A 419
ARG A 426
TRP A 427
None
0.65A 3kivA-4duuA:
14.4
3kivA-4duuA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OOI_A_SAMA237_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-36 AND H4
LYSINE-20 SPECIFIC)
4duu PLASMINOGEN
(Homo
sapiens)
5 / 12 GLY A 415
TRP A 417
HIS A 360
CYH A 435
CYH A 358
None
1.26A 3ooiA-4duuA:
undetectable
3ooiA-4duuA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_A_CHDA1507_0
(FERROCHELATASE,
MITOCHONDRIAL)
4duu PLASMINOGEN
(Homo
sapiens)
3 / 3 ARG A  68
LYS A 392
ARG A 426
None
1.20A 3w1wA-4duuA:
undetectable
3w1wB-4duuA:
undetectable
3w1wA-4duuA:
18.69
3w1wB-4duuA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_B_CHDB506_0
(FERROCHELATASE,
MITOCHONDRIAL)
4duu PLASMINOGEN
(Homo
sapiens)
3 / 3 ARG A 426
ARG A  68
LYS A 392
None
1.26A 3w1wA-4duuA:
undetectable
3w1wB-4duuA:
undetectable
3w1wA-4duuA:
18.69
3w1wB-4duuA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BVV_A_CPFA1081_1
(APOLIPOPROTEIN(A))
4duu PLASMINOGEN
(Homo
sapiens)
6 / 9 HIS A 494
ASP A 516
ASP A 518
TRP A 523
TYR A 525
LEU A 532
None
0.73A 4bvvA-4duuA:
15.6
4bvvA-4duuA:
26.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BVV_A_CPFA1081_1
(APOLIPOPROTEIN(A))
4duu PLASMINOGEN
(Homo
sapiens)
6 / 9 HIS A 494
SER A 495
ASP A 518
TRP A 523
TYR A 525
LEU A 532
None
0.92A 4bvvA-4duuA:
15.6
4bvvA-4duuA:
26.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B8I_C_FK5C201_2
(CALCINEURIN SUBUNIT
B, VARIANT
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)
4duu PLASMINOGEN
(Homo
sapiens)
4 / 4 LEU A 649
MET A 788
VAL A 787
ASN A 790
None
1.43A 5b8iB-4duuA:
undetectable
5b8iB-4duuA:
11.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXQ_A_NIZA808_1
(CATALASE-PEROXIDASE)
4duu PLASMINOGEN
(Homo
sapiens)
4 / 8 ARG A 677
GLU A 679
GLY A 728
LEU A 730
None
1.01A 5sxqA-4duuA:
undetectable
5sxqA-4duuA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXQ_B_NIZB808_1
(CATALASE-PEROXIDASE)
4duu PLASMINOGEN
(Homo
sapiens)
4 / 8 ARG A 677
GLU A 679
GLY A 728
LEU A 730
None
0.98A 5sxqB-4duuA:
undetectable
5sxqB-4duuA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXT_B_NIZB808_1
(CATALASE-PEROXIDASE)
4duu PLASMINOGEN
(Homo
sapiens)
4 / 8 ARG A 677
GLU A 679
GLY A 728
LEU A 730
None
0.99A 5sxtB-4duuA:
undetectable
5sxtB-4duuA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYJ_B_NIZB809_1
(CATALASE-PEROXIDASE)
4duu PLASMINOGEN
(Homo
sapiens)
4 / 8 ARG A 677
GLU A 679
GLY A 728
LEU A 730
None
1.00A 5syjB-4duuA:
undetectable
5syjB-4duuA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W4Z_A_RBFA502_2
(RIBOFLAVIN LYASE)
4duu PLASMINOGEN
(Homo
sapiens)
4 / 5 ASN A 409
GLN A 364
ASP A 413
ARG A  68
None
1.46A 5w4zA-4duuA:
undetectable
5w4zA-4duuA:
8.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5K_A_SAMA805_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-9 SPECIFIC
SUVH6)
4duu PLASMINOGEN
(Homo
sapiens)
5 / 12 GLY A 415
TRP A 417
HIS A 360
CYH A 435
CYH A 358
None
1.23A 6a5kA-4duuA:
undetectable
6a5kA-4duuA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5M_A_SAMA805_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-9 SPECIFIC
SUVH6)
4duu PLASMINOGEN
(Homo
sapiens)
5 / 12 GLY A 415
TRP A 417
HIS A 360
CYH A 435
CYH A 358
None
1.24A 6a5mA-4duuA:
undetectable
6a5mA-4duuA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_D_AQ4D602_0
(CYTOCHROME P450 1A1)
4duu PLASMINOGEN
(Homo
sapiens)
5 / 12 SER A 203
PHE A 227
GLY A 199
ALA A 675
ASP A 676
None
0.97A 6dwnD-4duuA:
undetectable
6dwnD-4duuA:
8.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBV_D_FI8D1904_0
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA
DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')
4duu PLASMINOGEN
(Homo
sapiens)
4 / 8 ILE A 754
THR A 591
VAL A 577
SER A 594
None
1.13A 6fbvC-4duuA:
undetectable
6fbvC-4duuA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB5_A_NMYA301_0
(AAC(3)-IIIB PROTEIN)
4duu PLASMINOGEN
(Homo
sapiens)
5 / 11 TYR A  92
ASP A 155
THR A  99
GLY A 142
ASP A 139
None
1.41A 6mb5A-4duuA:
undetectable
6mb5A-4duuA:
7.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB5_A_NMYA301_0
(AAC(3)-IIIB PROTEIN)
4duu PLASMINOGEN
(Homo
sapiens)
5 / 11 TYR A 470
ASP A 534
THR A 477
GLY A 521
ASP A 518
None
1.33A 6mb5A-4duuA:
undetectable
6mb5A-4duuA:
7.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB9_A_NMYA303_0
(AAC(3)-IIIB PROTEIN)
4duu PLASMINOGEN
(Homo
sapiens)
5 / 10 TYR A 470
ASP A 534
THR A 477
GLY A 521
ASP A 518
None
1.37A 6mb9A-4duuA:
undetectable
6mb9A-4duuA:
7.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB9_B_NMYB302_0
(AAC(3)-IIIB PROTEIN)
4duu PLASMINOGEN
(Homo
sapiens)
5 / 10 TYR A  92
ASP A 155
THR A  99
GLY A 142
ASP A 139
None
1.45A 6mb9B-4duuA:
undetectable
6mb9B-4duuA:
7.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB9_B_NMYB302_0
(AAC(3)-IIIB PROTEIN)
4duu PLASMINOGEN
(Homo
sapiens)
5 / 10 TYR A 470
ASP A 534
THR A 477
GLY A 521
ASP A 518
None
1.37A 6mb9B-4duuA:
undetectable
6mb9B-4duuA:
7.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB9_C_NMYC302_0
(AAC(3)-IIIB PROTEIN)
4duu PLASMINOGEN
(Homo
sapiens)
5 / 10 TYR A  92
ASP A 155
THR A  99
GLY A 142
ASP A 139
None
1.45A 6mb9C-4duuA:
undetectable
6mb9C-4duuA:
7.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB9_C_NMYC302_0
(AAC(3)-IIIB PROTEIN)
4duu PLASMINOGEN
(Homo
sapiens)
5 / 10 TYR A 470
ASP A 534
THR A 477
GLY A 521
ASP A 518
None
1.38A 6mb9C-4duuA:
undetectable
6mb9C-4duuA:
7.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB9_D_NMYD302_0
(AAC(3)-IIIB PROTEIN)
4duu PLASMINOGEN
(Homo
sapiens)
5 / 10 TYR A  92
ASP A 155
THR A  99
GLY A 142
ASP A 139
None
1.49A 6mb9D-4duuA:
undetectable
6mb9D-4duuA:
7.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB9_D_NMYD302_0
(AAC(3)-IIIB PROTEIN)
4duu PLASMINOGEN
(Homo
sapiens)
5 / 10 TYR A 470
ASP A 534
THR A 477
GLY A 521
ASP A 518
None
1.40A 6mb9D-4duuA:
undetectable
6mb9D-4duuA:
7.87