SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4dve'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_C_ADNC603_2
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 4dve BIOTIN TRANSPORTER
BIOY
(Lactococcus
lactis) 		4 / 5 THR A 170
GLU A 121
THR A 113
LEU A  51
 None
 1.27A 1d4fC-4dveA:
undetectable		 1d4fC-4dveA:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FFY_A_MRCA1993_1
(ISOLEUCYL-TRNA
SYNTHETASE)		 4dve BIOTIN TRANSPORTER
BIOY
(Lactococcus
lactis) 		5 / 12 PRO A  35
ASN A 156
GLY A 137
VAL A 130
MET A  46
 None
 1.06A 1ffyA-4dveA:
undetectable		 1ffyA-4dveA:
12.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_A_DVAA8_0
(GRAMICIDIN A)		 4dve BIOTIN TRANSPORTER
BIOY
(Lactococcus
lactis) 		3 / 4 VAL A 133
TRP A 140
TRP A  96
 None
None
BTN  A 201 ( 4.8A)
 1.31A 1gmkA-4dveA:
undetectable
1gmkB-4dveA:
undetectable		 1gmkA-4dveA:
14.46
1gmkB-4dveA:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_C_DVAC8_0
(GRAMICIDIN A)		 4dve BIOTIN TRANSPORTER
BIOY
(Lactococcus
lactis) 		3 / 4 VAL A 133
TRP A 140
TRP A  96
 None
None
BTN  A 201 ( 4.8A)
 1.18A 1gmkC-4dveA:
undetectable
1gmkD-4dveA:
undetectable		 1gmkC-4dveA:
14.46
1gmkD-4dveA:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MTE_B_SAMB220_0
(16S RRNA METHYLASE)		 4dve BIOTIN TRANSPORTER
BIOY
(Lactococcus
lactis) 		5 / 12 GLY A  49
GLY A  57
LEU A  51
PHE A 183
LEU A 107
 None
 1.00A 3mteB-4dveA:
undetectable		 3mteB-4dveA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_A_SAMA6735_0
(16S RRNA METHYLASE)		 4dve BIOTIN TRANSPORTER
BIOY
(Lactococcus
lactis) 		5 / 12 GLY A  49
GLY A  57
LEU A  51
PHE A 183
LEU A 107
 None
 1.02A 3p2kA-4dveA:
undetectable		 3p2kA-4dveA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_C_SAMC6735_0
(16S RRNA METHYLASE)		 4dve BIOTIN TRANSPORTER
BIOY
(Lactococcus
lactis) 		5 / 12 GLY A  49
GLY A  57
LEU A  51
PHE A 183
LEU A 107
 None
 1.02A 3p2kC-4dveA:
undetectable		 3p2kC-4dveA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U7S_A_017A202_2
(POL POLYPROTEIN)		 4dve BIOTIN TRANSPORTER
BIOY
(Lactococcus
lactis) 		5 / 9 GLY A  49
ALA A  48
GLY A 129
LEU A  97
VAL A  61
 None
 0.69A 3u7sB-4dveA:
undetectable		 3u7sB-4dveA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J26_B_ESTB600_1
(ESTROGEN RECEPTOR
BETA)		 4dve BIOTIN TRANSPORTER
BIOY
(Lactococcus
lactis) 		5 / 12 LEU A  97
LEU A  69
ILE A  20
ILE A  21
LEU A  75
 None
None
None
BNG  A 202 ( 4.2A)
BTN  A 201 ( 3.8A)
 1.30A 4j26B-4dveA:
undetectable		 4j26B-4dveA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_B_SORB1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 4dve BIOTIN TRANSPORTER
BIOY
(Lactococcus
lactis) 		4 / 7 ILE A 103
LYS A 108
LEU A 107
GLY A  50
 None
BNG  A 203 (-2.2A)
None
None
 0.73A 5a06B-4dveA:
undetectable		 5a06B-4dveA:
19.40