SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4dvj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_J_TRPJ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4dvj PUTATIVE
ZINC-DEPENDENT
ALCOHOL
DEHYDROGENASE
PROTEIN
(Rhizobium
etli) 		4 / 8 GLY A 179
ALA A 188
THR A 246
ILE A 177
 None
 0.74A 1c9sI-4dvjA:
undetectable
1c9sJ-4dvjA:
undetectable		 1c9sI-4dvjA:
12.98
1c9sJ-4dvjA:
12.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4dvj PUTATIVE
ZINC-DEPENDENT
ALCOHOL
DEHYDROGENASE
PROTEIN
(Rhizobium
etli) 		4 / 8 GLY A 179
ALA A 188
THR A 246
ILE A 177
 None
 0.75A 1c9sU-4dvjA:
undetectable
1c9sV-4dvjA:
undetectable		 1c9sU-4dvjA:
12.98
1c9sV-4dvjA:
12.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_A_PFLA4002_1
(SERUM ALBUMIN)		 4dvj PUTATIVE
ZINC-DEPENDENT
ALCOHOL
DEHYDROGENASE
PROTEIN
(Rhizobium
etli) 		3 / 3 PHE A 110
LEU A 309
SER A 151
 None
 0.85A 1e7aA-4dvjA:
undetectable		 1e7aA-4dvjA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_B_HLTB4002_1
(SERUM ALBUMIN)		 4dvj PUTATIVE
ZINC-DEPENDENT
ALCOHOL
DEHYDROGENASE
PROTEIN
(Rhizobium
etli) 		4 / 4 ARG A 329
ALA A  61
ALA A 144
GLU A 143
 None
 1.26A 1e7bB-4dvjA:
undetectable		 1e7bB-4dvjA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4002_1
(SERUM ALBUMIN)		 4dvj PUTATIVE
ZINC-DEPENDENT
ALCOHOL
DEHYDROGENASE
PROTEIN
(Rhizobium
etli) 		4 / 5 ARG A 329
ALA A  61
ALA A 144
GLU A 143
 None
 1.19A 1e7cA-4dvjA:
undetectable		 1e7cA-4dvjA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4dvj PUTATIVE
ZINC-DEPENDENT
ALCOHOL
DEHYDROGENASE
PROTEIN
(Rhizobium
etli) 		4 / 7 GLY A 179
ALA A 188
THR A 246
ILE A 177
 None
 0.76A 1gtnA-4dvjA:
undetectable
1gtnK-4dvjA:
undetectable		 1gtnA-4dvjA:
12.98
1gtnK-4dvjA:
12.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4dvj PUTATIVE
ZINC-DEPENDENT
ALCOHOL
DEHYDROGENASE
PROTEIN
(Rhizobium
etli) 		4 / 8 GLY A 179
ALA A 188
THR A 246
ILE A 177
 None
 0.73A 1gtnE-4dvjA:
undetectable
1gtnF-4dvjA:
undetectable		 1gtnE-4dvjA:
12.98
1gtnF-4dvjA:
12.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_B_SAMB1293_0
(GLYCINE
N-METHYLTRANSFERASE)		 4dvj PUTATIVE
ZINC-DEPENDENT
ALCOHOL
DEHYDROGENASE
PROTEIN
(Rhizobium
etli) 		5 / 12 ILE A  55
GLY A  91
VAL A  93
ALA A 142
GLY A 133
 None
 1.22A 1kiaB-4dvjA:
8.8		 1kiaB-4dvjA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_B_ACTB1868_0
(FPRA)		 4dvj PUTATIVE
ZINC-DEPENDENT
ALCOHOL
DEHYDROGENASE
PROTEIN
(Rhizobium
etli) 		3 / 3 ALA A 341
HIS A 342
VAL A 345
 None
 0.48A 1lqtB-4dvjA:
3.2		 1lqtB-4dvjA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_B_ACTB1425_0
(FPRA)		 4dvj PUTATIVE
ZINC-DEPENDENT
ALCOHOL
DEHYDROGENASE
PROTEIN
(Rhizobium
etli) 		3 / 3 ALA A 341
HIS A 342
VAL A 345
 None
 0.50A 1lquB-4dvjA:
undetectable		 1lquB-4dvjA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q8J_B_C2FB802_0
(5-METHYLTETRAHYDROFO
LATE S-HOMOCYSTEINE
METHYLTRANSFERASE)		 4dvj PUTATIVE
ZINC-DEPENDENT
ALCOHOL
DEHYDROGENASE
PROTEIN
(Rhizobium
etli) 		5 / 12 ASP A 107
ILE A  55
GLY A 133
SER A 314
ASN A 311
 None
 1.11A 1q8jB-4dvjA:
3.0		 1q8jB-4dvjA:
23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_I_TRPI81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4dvj PUTATIVE
ZINC-DEPENDENT
ALCOHOL
DEHYDROGENASE
PROTEIN
(Rhizobium
etli) 		4 / 8 GLY A 179
ALA A 188
THR A 246
ILE A 177
 None
 0.72A 1utdI-4dvjA:
undetectable
1utdJ-4dvjA:
undetectable		 1utdI-4dvjA:
12.98
1utdJ-4dvjA:
12.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E7F_A_C2FA3000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 4dvj PUTATIVE
ZINC-DEPENDENT
ALCOHOL
DEHYDROGENASE
PROTEIN
(Rhizobium
etli) 		5 / 12 ASP A 107
ILE A  55
GLY A 133
SER A 314
ASN A 311
 None
 1.09A 2e7fA-4dvjA:
3.2		 2e7fA-4dvjA:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GJ5_A_VD3A163_1
(BETA-LACTOGLOBULIN)		 4dvj PUTATIVE
ZINC-DEPENDENT
ALCOHOL
DEHYDROGENASE
PROTEIN
(Rhizobium
etli) 		5 / 12 LEU A 309
VAL A 317
LEU A 322
ILE A 187
PHE A 110
 None
 0.74A 2gj5A-4dvjA:
undetectable		 2gj5A-4dvjA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2O_B_DHIB24_0
(INSULIN B CHAIN)		 4dvj PUTATIVE
ZINC-DEPENDENT
ALCOHOL
DEHYDROGENASE
PROTEIN
(Rhizobium
etli) 		4 / 6 GLY A 320
PRO A 136
LYS A 137
THR A 138
 None
 1.27A 2m2oB-4dvjA:
undetectable		 2m2oB-4dvjA:
6.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VE3_A_REAA1445_1
(PUTATIVE CYTOCHROME
P450 120)		 4dvj PUTATIVE
ZINC-DEPENDENT
ALCOHOL
DEHYDROGENASE
PROTEIN
(Rhizobium
etli) 		5 / 12 LEU A 162
PHE A 158
ALA A 157
VAL A 184
GLY A 183
 None
 1.02A 2ve3A-4dvjA:
undetectable		 2ve3A-4dvjA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGD_A_PM6A301_1
(THIOPURINE
S-METHYLTRANSFERASE)		 4dvj PUTATIVE
ZINC-DEPENDENT
ALCOHOL
DEHYDROGENASE
PROTEIN
(Rhizobium
etli) 		4 / 6 PHE A 242
ALA A 171
LEU A 259
PRO A 240
 None
 0.85A 3bgdA-4dvjA:
7.4		 3bgdA-4dvjA:
23.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DH0_B_SAMB300_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 4dvj PUTATIVE
ZINC-DEPENDENT
ALCOHOL
DEHYDROGENASE
PROTEIN
(Rhizobium
etli) 		5 / 12 GLY A 179
GLY A 185
ALA A 204
THR A 203
LEU A 228
 None
 0.88A 3dh0B-4dvjA:
8.8		 3dh0B-4dvjA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HEC_A_STIA1_2
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)		 4dvj PUTATIVE
ZINC-DEPENDENT
ALCOHOL
DEHYDROGENASE
PROTEIN
(Rhizobium
etli) 		4 / 4 LEU A  40
MET A  23
ILE A 115
ASP A  88
 None
 1.45A 3hecA-4dvjA:
undetectable		 3hecA-4dvjA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDT_A_VORA506_1
(CHOLESTEROL
24-HYDROXYLASE)		 4dvj PUTATIVE
ZINC-DEPENDENT
ALCOHOL
DEHYDROGENASE
PROTEIN
(Rhizobium
etli) 		5 / 9 VAL A 285
SER A 286
ILE A 256
ALA A 257
ALA A 239
 None
 1.28A 3mdtA-4dvjA:
undetectable		 3mdtA-4dvjA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFU_C_RBVC601_1
(RNA POLYMERASE)		 4dvj PUTATIVE
ZINC-DEPENDENT
ALCOHOL
DEHYDROGENASE
PROTEIN
(Rhizobium
etli) 		5 / 11 ASP A  68
SER A  63
THR A 120
ASN A 121
GLY A 119
 None
 1.35A 3sfuC-4dvjA:
undetectable		 3sfuC-4dvjA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQ6_B_ADNB401_1
(ADENOSINE KINASE,
PUTATIVE)		 4dvj PUTATIVE
ZINC-DEPENDENT
ALCOHOL
DEHYDROGENASE
PROTEIN
(Rhizobium
etli) 		5 / 12 ILE A 269
GLY A 183
THR A 153
LEU A 149
GLY A 179
 None
 0.85A 3uq6B-4dvjA:
3.4		 3uq6B-4dvjA:
24.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V35_A_NTIA317_1
(ALDOSE REDUCTASE)		 4dvj PUTATIVE
ZINC-DEPENDENT
ALCOHOL
DEHYDROGENASE
PROTEIN
(Rhizobium
etli) 		4 / 8 VAL A 178
HIS A 252
PHE A 266
PRO A 240
 None
 1.45A 3v35A-4dvjA:
undetectable		 3v35A-4dvjA:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAQ_B_ADNB401_1
(PUTATIVE ADENOSINE
KINASE)		 4dvj PUTATIVE
ZINC-DEPENDENT
ALCOHOL
DEHYDROGENASE
PROTEIN
(Rhizobium
etli) 		5 / 12 ILE A 269
GLY A 183
THR A 153
LEU A 149
GLY A 179
 None
 0.90A 3vaqB-4dvjA:
3.7		 3vaqB-4dvjA:
24.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HTF_A_SAMA301_0
(S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 4dvj PUTATIVE
ZINC-DEPENDENT
ALCOHOL
DEHYDROGENASE
PROTEIN
(Rhizobium
etli) 		5 / 12 GLY A 185
GLY A 180
GLY A 179
SER A 245
ALA A 154
 None
 0.93A 4htfA-4dvjA:
8.7		 4htfA-4dvjA:
26.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HTF_B_SAMB301_0
(S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 4dvj PUTATIVE
ZINC-DEPENDENT
ALCOHOL
DEHYDROGENASE
PROTEIN
(Rhizobium
etli) 		5 / 12 GLY A 185
GLY A 180
GLY A 179
SER A 245
ALA A 154
 None
 0.96A 4htfB-4dvjA:
8.5		 4htfB-4dvjA:
26.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYT_A_OBNA1104_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 4dvj PUTATIVE
ZINC-DEPENDENT
ALCOHOL
DEHYDROGENASE
PROTEIN
(Rhizobium
etli) 		4 / 5 PRO A 272
ASP A 270
ILE A 287
VAL A 243
 None
 1.28A 4hytA-4dvjA:
2.7		 4hytA-4dvjA:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_C_ADNC401_2
(ADENOSINE KINASE)		 4dvj PUTATIVE
ZINC-DEPENDENT
ALCOHOL
DEHYDROGENASE
PROTEIN
(Rhizobium
etli) 		4 / 5 ASN A 328
LEU A 330
LEU A 338
ASN A 121
 None
 1.04A 4n09C-4dvjA:
4.6		 4n09C-4dvjA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PFJ_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 4dvj PUTATIVE
ZINC-DEPENDENT
ALCOHOL
DEHYDROGENASE
PROTEIN
(Rhizobium
etli) 		4 / 7 THR A 209
LEU A 344
ASN A 328
SER A 186
 None
 1.09A 4pfjA-4dvjA:
9.7		 4pfjA-4dvjA:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4dvj PUTATIVE
ZINC-DEPENDENT
ALCOHOL
DEHYDROGENASE
PROTEIN
(Rhizobium
etli) 		5 / 10 ALA A 202
THR A 203
ALA A 204
VAL A 200
GLY A 185
 None
 0.91A 4qvyK-4dvjA:
undetectable
4qvyL-4dvjA:
undetectable		 4qvyK-4dvjA:
19.17
4qvyL-4dvjA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4dvj PUTATIVE
ZINC-DEPENDENT
ALCOHOL
DEHYDROGENASE
PROTEIN
(Rhizobium
etli) 		5 / 10 ALA A 202
THR A 203
ALA A 204
VAL A 200
GLY A 185
 None
 0.91A 4qvyY-4dvjA:
undetectable
4qvyZ-4dvjA:
undetectable		 4qvyY-4dvjA:
19.17
4qvyZ-4dvjA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_K_6V8K305_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-5)		 4dvj PUTATIVE
ZINC-DEPENDENT
ALCOHOL
DEHYDROGENASE
PROTEIN
(Rhizobium
etli) 		5 / 11 ALA A 202
THR A 203
ALA A 204
VAL A 200
GLY A 185
 None
 0.80A 5lf7K-4dvjA:
undetectable
5lf7L-4dvjA:
undetectable		 5lf7K-4dvjA:
18.57
5lf7L-4dvjA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_Y_6V8Y306_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-5)		 4dvj PUTATIVE
ZINC-DEPENDENT
ALCOHOL
DEHYDROGENASE
PROTEIN
(Rhizobium
etli) 		5 / 11 ALA A 202
THR A 203
ALA A 204
VAL A 200
GLY A 185
 None
 0.80A 5lf7Y-4dvjA:
undetectable
5lf7Z-4dvjA:
undetectable		 5lf7Y-4dvjA:
18.57
5lf7Z-4dvjA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZY_A_CE3A1103_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 4dvj PUTATIVE
ZINC-DEPENDENT
ALCOHOL
DEHYDROGENASE
PROTEIN
(Rhizobium
etli) 		4 / 8 THR A 294
PRO A 296
ASP A  88
GLY A 307
 None
 0.96A 5nzyA-4dvjA:
3.4		 5nzyA-4dvjA:
18.04