SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4dw2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSD_C_DVAC2_0
(ACTINOMYCIN D)		 4dw2 FAB FRAGMENT OF
PRO-UPA ANTIBODY
MAB-112
(Mus
musculus) 		4 / 4 THR H 116
PRO H 118
THR H 117
PRO H 141
 None
 1.35A 1dsdC-4dw2H:
undetectable		 1dsdC-4dw2H:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSD_C_DVAC2_0
(ACTINOMYCIN D)		 4dw2 FAB FRAGMENT OF
PRO-UPA ANTIBODY
MAB-112
(Mus
musculus) 		4 / 4 THR H 117
PRO H 141
THR H 116
PRO H 118
 None
 1.21A 1dsdC-4dw2H:
undetectable		 1dsdC-4dw2H:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSD_C_DVAC8_0
(ACTINOMYCIN D)		 4dw2 FAB FRAGMENT OF
PRO-UPA ANTIBODY
MAB-112
(Mus
musculus) 		4 / 4 THR H 116
PRO H 118
THR H 117
PRO H 141
 None
 1.35A 1dsdC-4dw2H:
undetectable		 1dsdC-4dw2H:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSD_C_DVAC8_0
(ACTINOMYCIN D)		 4dw2 FAB FRAGMENT OF
PRO-UPA ANTIBODY
MAB-112
(Mus
musculus) 		4 / 4 THR H 117
PRO H 141
THR H 116
PRO H 118
 None
 1.21A 1dsdC-4dw2H:
undetectable		 1dsdC-4dw2H:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJX_H_HCZH800_1
(GLUTAMATE RECEPTOR 2)		 4dw2 FAB FRAGMENT OF
PRO-UPA ANTIBODY
MAB-112
(Mus
musculus) 		4 / 5 LYS H  13
PRO H  14
SER H  84
SER H  82
 None
 1.38A 3ijxH-4dw2H:
undetectable		 3ijxH-4dw2H:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AF0_A_MOAA1526_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 4dw2 FAB FRAGMENT OF
PRO-UPA ANTIBODY
MAB-112
(Mus
musculus) 		4 / 8 SER H  30
ASN H  73
ARG H  71
GLY H  26
 None
 1.02A 4af0A-4dw2H:
undetectable		 4af0A-4dw2H:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EYP_B_LOCB502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 4dw2 FAB FRAGMENT OF
PRO-UPA ANTIBODY
MAB-112
(Mus
musculus) 		3 / 3 SER H 197
ALA H 192
VAL H 191
 None
 0.56A 5eypA-4dw2H:
undetectable		 5eypA-4dw2H:
17.50