SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4dwe'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEB_A_AMHA90_1
(PLASMINOGEN)		 4dwe UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		4 / 7 ARG A 270
ASP A 289
TYR A 371
TYR A 375
 None
 1.47A 1cebA-4dweA:
undetectable		 1cebA-4dweA:
10.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PJ7_A_FFOA2887_1
(N,N-DIMETHYLGLYCINE
OXIDASE)		 4dwe UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		3 / 3 ASP A 431
THR A 433
GLU A 456
 None
 0.84A 1pj7A-4dweA:
undetectable		 1pj7A-4dweA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOQ_B_ROFB501_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 4dwe UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		3 / 3 MET A 420
ASN A 447
GLN A 155
 None
 1.03A 1xoqB-4dweA:
undetectable		 1xoqB-4dweA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_A_SAMA301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 4dwe UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		3 / 3 LYS A 145
ASP A 360
ASN A 351
 None
 1.09A 2bm9A-4dweA:
undetectable		 2bm9A-4dweA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_B_SAMB301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 4dwe UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		4 / 4 LEU A 250
SER A 276
ASP A 256
ASP A 219
 None
 1.31A 2br4B-4dweA:
undetectable		 2br4B-4dweA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_C_SAMC300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 4dwe UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		4 / 4 SER A 473
GLY A 117
HIS A 457
ASP A 449
 GOL  A 504 ( 4.3A)
None
None
None
 1.30A 2oxtC-4dweA:
undetectable		 2oxtC-4dweA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S8P_A_SAMA500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 4dwe UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		3 / 3 HIS A 390
SER A 425
GLU A 424
 None
 0.88A 3s8pA-4dweA:
undetectable		 3s8pA-4dweA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ7_A_SAMA301_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 4dwe UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		3 / 3 SER A 436
ASP A 439
ASP A 442
 None
 0.90A 3uj7A-4dweA:
undetectable		 3uj7A-4dweA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7G_A_ACTA514_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 4dwe UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		4 / 4 ALA A 234
VAL A 233
ASP A 168
LEU A 217
 None
 1.28A 4e7gA-4dweA:
undetectable		 4e7gA-4dweA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_A_DAHA304_1
(TYROSINASE)		 4dwe UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		4 / 5 ASN A 205
HIS A 457
GLU A 202
THR A  51
 None
None
GOL  A 504 (-3.7A)
None
 1.27A 4p6sA-4dweA:
undetectable		 4p6sA-4dweA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4POO_A_SAMA301_0
(PUTATIVE RNA
METHYLASE)		 4dwe UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		5 / 12 THR A 391
SER A 425
HIS A  71
LEU A  81
THR A  69
 None
 1.26A 4pooA-4dweA:
undetectable		 4pooA-4dweA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R87_I_SPMI202_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 4dwe UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		4 / 7 ASN A 366
GLU A 368
TYR A 370
GLU A 369
 None
 1.37A 4r87I-4dweA:
undetectable		 4r87I-4dweA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA302_0
(THAUMATIN-1)		 4dwe UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		3 / 3 ARG A 464
GLN A 132
GLU A 202
 GOL  A 504 (-3.8A)
None
GOL  A 504 (-3.7A)
 0.86A 4tvtA-4dweA:
undetectable		 4tvtA-4dweA:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LAK_I_BEZI1_0
(3CL PROTEASE
BEZ-TYR-TYR-ASN-ECC
PEPTIDE INHIBITOR)		 4dwe UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		3 / 3 SER A 121
TYR A 140
TYR A 141
 None
 0.71A 5lakA-4dweA:
undetectable
5lakI-4dweA:
undetectable		 5lakA-4dweA:
21.15
5lakI-4dweA:
1.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LAK_J_BEZJ1_0
(3CL PROTEASE
BEZ-TYR-TYR-ASN-ECC
PEPTIDE INHIBITOR)		 4dwe UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		3 / 3 SER A 121
TYR A 140
TYR A 141
 None
 0.78A 5lakC-4dweA:
undetectable
5lakJ-4dweA:
undetectable		 5lakC-4dweA:
21.15
5lakJ-4dweA:
1.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NCD_A_ACTA301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 4dwe UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		4 / 6 ASP A 101
ASP A 102
HIS A 213
HIS A 337
 GOL  A 500 (-3.4A)
GOL  A 500 ( 4.4A)
GOL  A 500 (-4.2A)
GOL  A 500 (-4.0A)
 0.43A 5ncdA-4dweA:
8.8
5ncdD-4dweA:
9.2		 5ncdA-4dweA:
19.71
5ncdD-4dweA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NCD_C_ACTC301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 4dwe UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		4 / 6 ASP A 101
ASP A 102
HIS A 213
HIS A 337
 GOL  A 500 (-3.4A)
GOL  A 500 ( 4.4A)
GOL  A 500 (-4.2A)
GOL  A 500 (-4.0A)
 0.45A 5ncdB-4dweA:
9.3
5ncdC-4dweA:
9.6		 5ncdB-4dweA:
19.71
5ncdC-4dweA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND2_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 4dwe UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		5 / 12 GLU A 368
LEU A 215
ALA A 211
SER A 209
ARG A 245
 None
 1.42A 5nd2B-4dweA:
undetectable		 5nd2B-4dweA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEK_B_AZMB302_1
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 4dwe UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		5 / 8 ASP A 101
ASP A 102
HIS A 213
PRO A 253
HIS A 337
 GOL  A 500 (-3.4A)
GOL  A 500 ( 4.4A)
GOL  A 500 (-4.2A)
None
GOL  A 500 (-4.0A)
 0.54A 5nekB-4dweA:
9.6		 5nekB-4dweA:
10.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEK_B_AZMB302_1
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 4dwe UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		4 / 8 ASP A 127
HIS A 105
ARG A  44
HIS A 130
 None
 0.98A 5nekB-4dweA:
9.6		 5nekB-4dweA:
10.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEK_D_AZMD302_1
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 4dwe UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		4 / 8 ASP A 101
ASP A 102
HIS A 213
HIS A 337
 GOL  A 500 (-3.4A)
GOL  A 500 ( 4.4A)
GOL  A 500 (-4.2A)
GOL  A 500 (-4.0A)
 0.54A 5nekD-4dweA:
9.7		 5nekD-4dweA:
10.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEK_D_AZMD302_1
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 4dwe UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		4 / 8 ASP A 127
HIS A 105
ARG A  44
HIS A 130
 None
 0.91A 5nekD-4dweA:
9.7		 5nekD-4dweA:
10.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEL_A_ACTA302_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 4dwe UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		4 / 6 ASP A 101
ASP A 102
HIS A 213
HIS A 337
 GOL  A 500 (-3.4A)
GOL  A 500 ( 4.4A)
GOL  A 500 (-4.2A)
GOL  A 500 (-4.0A)
 0.49A 5nelA-4dweA:
9.6
5nelD-4dweA:
9.2		 5nelA-4dweA:
19.71
5nelD-4dweA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_C_CUC601_0
(THIOCYANATE
DEHYDROGENASE)		 4dwe UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		3 / 3 HIS A 337
ASP A 102
HIS A 213
 GOL  A 500 (-4.0A)
GOL  A 500 ( 4.4A)
GOL  A 500 (-4.2A)
 0.78A 5oexC-4dweA:
undetectable		 5oexC-4dweA:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V4V_B_NCAB402_0
(NADPH DEHYDROGENASE
3)		 4dwe UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		4 / 8 TRP A 112
ASN A 205
TYR A 206
PHE A 461
 None
 1.23A 5v4vB-4dweA:
3.1		 5v4vB-4dweA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EFN_A_SAMA501_0
(SPORULATION KILLING
FACTOR MATURATION
PROTEIN SKFB)		 4dwe UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		5 / 11 TYR A 266
THR A 246
GLU A 368
ALA A 167
ALA A 262
 None
 1.08A 6efnA-4dweA:
undetectable		 6efnA-4dweA:
20.39