SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4dx0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFU_C_RBVC601_1
(RNA POLYMERASE)		 4dx0 14-3-3-LIKE PROTEIN
E
(Nicotiana
tabacum) 		5 / 11 ARG A  61
LEU A  97
LEU A 105
GLY A 130
ASP A 131
 None
 1.45A 3sfuC-4dx0A:
undetectable		 3sfuC-4dx0A:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E0F_A_RBFA301_2
(RIBOFLAVIN SYNTHASE
SUBUNIT ALPHA)		 4dx0 14-3-3-LIKE PROTEIN
E
(Nicotiana
tabacum) 		3 / 3 LYS A 218
THR A 222
ILE A 207
 None
 0.64A 4e0fB-4dx0A:
undetectable		 4e0fB-4dx0A:
26.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JM4_A_BEZA301_0
(14-3-3 PROTEIN
ZETA/DELTA)		 4dx0 14-3-3-LIKE PROTEIN
E
(Nicotiana
tabacum) 		4 / 5 PHE A 203
ILE A 207
MET A 225
ARG A 229
 None
 1.01A 5jm4A-4dx0A:
30.2		 5jm4A-4dx0A:
64.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JM4_A_BEZA301_0
(14-3-3 PROTEIN
ZETA/DELTA)		 4dx0 14-3-3-LIKE PROTEIN
E
(Nicotiana
tabacum) 		4 / 5 PHE A 203
ILE A 207
MET A 225
GLN A 226
 None
 0.41A 5jm4A-4dx0A:
30.2		 5jm4A-4dx0A:
64.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5M35_A_BEZA302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 4dx0 14-3-3-LIKE PROTEIN
E
(Nicotiana
tabacum) 		4 / 5 PHE A 203
THR A 222
MET A 225
GLN A 226
 None
 0.57A 5m35A-4dx0A:
30.8		 5m35A-4dx0A:
63.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6FI4_B_DVAB8_0
(14-3-3 PROTEIN SIGMA
PRO-SEP-LEU-PRO-DVA)		 4dx0 14-3-3-LIKE PROTEIN
E
(Nicotiana
tabacum) 		4 / 5 SER A  50
VAL A  51
LYS A  54
ASN A  55
 0MT  A 301 ( 3.8A)
0MT  A 301 (-4.1A)
0MT  A 301 (-4.4A)
0MT  A 301 ( 4.9A)
 0.42A 6fi4A-4dx0A:
28.7
6fi4B-4dx0A:
undetectable		 6fi4A-4dx0A:
61.83
6fi4B-4dx0A:
3.33