SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4dxe'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FKB_A_RAPA108_1
(FK506 BINDING
PROTEIN)		 4dxe ACYL-CARRIER-PROTEIN
SYNTHASE
(Staphylococcus
aureus) 		5 / 12 PHE A  38
GLU A  44
ILE A  15
HIS A 103
ILE A 101
 None
None
None
MLI  A 201 (-4.4A)
MLI  A 201 ( 4.1A)
 1.21A 1fkbA-4dxeA:
undetectable		 1fkbA-4dxeA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DG3_A_RAPA501_1
(FK506-BINDING
PROTEIN 1A)		 4dxe ACYL-CARRIER-PROTEIN
SYNTHASE
(Staphylococcus
aureus) 		5 / 11 PHE A  38
GLU A  44
ILE A  15
HIS A 103
ILE A 101
 None
None
None
MLI  A 201 (-4.4A)
MLI  A 201 ( 4.1A)
 1.27A 2dg3A-4dxeA:
undetectable		 2dg3A-4dxeA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DG4_A_RAPA501_1
(FK506-BINDING
PROTEIN 1A)		 4dxe ACYL-CARRIER-PROTEIN
SYNTHASE
(Staphylococcus
aureus) 		5 / 11 PHE A  38
GLU A  44
ILE A  15
HIS A 103
ILE A 101
 None
None
None
MLI  A 201 (-4.4A)
MLI  A 201 ( 4.1A)
 1.23A 2dg4A-4dxeA:
undetectable		 2dg4A-4dxeA:
20.71