SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4dxy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AKD_A_CAMA420_0
(CYTOCHROME P450CAM)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		6 / 11 PHE A  87
THR A 101
LEU A 250
GLY A 254
THR A 258
VAL A 301
 None
HEM  A 501 ( 4.8A)
HEM  A 501 (-4.3A)
PEG  A 502 (-3.8A)
HEM  A 501 (-3.7A)
PEG  A 502 ( 4.5A)
 1.49A 1akdA-4dxyA:
50.9		 1akdA-4dxyA:
46.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AKD_A_CAMA420_0
(CYTOCHROME P450CAM)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		7 / 11 PHE A  87
THR A 101
LEU A 250
GLY A 254
THR A 258
VAL A 301
VAL A 402
 None
HEM  A 501 ( 4.8A)
HEM  A 501 (-4.3A)
PEG  A 502 (-3.8A)
HEM  A 501 (-3.7A)
PEG  A 502 ( 4.5A)
None
 1.02A 1akdA-4dxyA:
50.9		 1akdA-4dxyA:
46.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AKD_A_CAMA420_0
(CYTOCHROME P450CAM)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		5 / 11 THR A 101
THR A 185
LEU A 250
GLY A 254
THR A 258
 HEM  A 501 ( 4.8A)
None
HEM  A 501 (-4.3A)
PEG  A 502 (-3.8A)
HEM  A 501 (-3.7A)
 1.02A 1akdA-4dxyA:
50.9		 1akdA-4dxyA:
46.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DZ8_A_CAMA503_0
(CYTOCHROME P450-CAM)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		6 / 9 PHE A  87
THR A 101
LEU A 250
GLY A 254
THR A 258
VAL A 301
 None
HEM  A 501 ( 4.8A)
HEM  A 501 (-4.3A)
PEG  A 502 (-3.8A)
HEM  A 501 (-3.7A)
PEG  A 502 ( 4.5A)
 0.89A 1dz8A-4dxyA:
52.4		 1dz8A-4dxyA:
46.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DZ8_B_CAMB502_0
(CYTOCHROME P450-CAM)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		5 / 9 PHE A  87
LEU A 250
GLY A 254
THR A 258
VAL A 301
 None
HEM  A 501 (-4.3A)
PEG  A 502 (-3.8A)
HEM  A 501 (-3.7A)
PEG  A 502 ( 4.5A)
 0.63A 1dz8B-4dxyA:
52.3		 1dz8B-4dxyA:
46.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DZ8_B_CAMB502_0
(CYTOCHROME P450-CAM)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		5 / 9 THR A 101
LEU A 250
GLY A 254
THR A 258
VAL A 301
 HEM  A 501 ( 4.8A)
HEM  A 501 (-4.3A)
PEG  A 502 (-3.8A)
HEM  A 501 (-3.7A)
PEG  A 502 ( 4.5A)
 0.81A 1dz8B-4dxyA:
52.3		 1dz8B-4dxyA:
46.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DZ9_A_CAMA503_0
(CYTOCHROME P450-CAM)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		4 / 8 PHE A  87
LEU A 250
THR A 258
VAL A 301
 None
HEM  A 501 (-4.3A)
HEM  A 501 (-3.7A)
PEG  A 502 ( 4.5A)
 0.56A 1dz9A-4dxyA:
52.5		 1dz9A-4dxyA:
46.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DZ9_A_CAMA503_0
(CYTOCHROME P450-CAM)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		4 / 8 THR A 101
LEU A 250
THR A 258
VAL A 301
 HEM  A 501 ( 4.8A)
HEM  A 501 (-4.3A)
HEM  A 501 (-3.7A)
PEG  A 502 ( 4.5A)
 0.78A 1dz9A-4dxyA:
52.5		 1dz9A-4dxyA:
46.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DZ9_B_CAMB502_0
(CYTOCHROME P450-CAM)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		5 / 9 PHE A  87
LEU A 250
GLY A 254
THR A 258
VAL A 301
 None
HEM  A 501 (-4.3A)
PEG  A 502 (-3.8A)
HEM  A 501 (-3.7A)
PEG  A 502 ( 4.5A)
 0.63A 1dz9B-4dxyA:
52.3		 1dz9B-4dxyA:
46.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DZ9_B_CAMB502_0
(CYTOCHROME P450-CAM)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		5 / 9 THR A 101
LEU A 250
GLY A 254
THR A 258
VAL A 301
 HEM  A 501 ( 4.8A)
HEM  A 501 (-4.3A)
PEG  A 502 (-3.8A)
HEM  A 501 (-3.7A)
PEG  A 502 ( 4.5A)
 0.78A 1dz9B-4dxyA:
52.3		 1dz9B-4dxyA:
46.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1IWI_A_CAMA418_0
(CYTOCHROME P450-CAM)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		5 / 8 PHE A  87
THR A 101
LEU A 250
VAL A 301
VAL A 402
 None
HEM  A 501 ( 4.8A)
HEM  A 501 (-4.3A)
PEG  A 502 ( 4.5A)
None
 0.86A 1iwiA-4dxyA:
51.7		 1iwiA-4dxyA:
46.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1IWJ_A_CAMA418_0
(CYTOCHROME P450-CAM)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		5 / 9 PHE A  87
THR A 101
LEU A 250
VAL A 301
VAL A 402
 None
HEM  A 501 ( 4.8A)
HEM  A 501 (-4.3A)
PEG  A 502 ( 4.5A)
None
 0.89A 1iwjA-4dxyA:
51.7		 1iwjA-4dxyA:
46.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1O76_A_CAMA1420_0
(CYTOCHROME P450-CAM)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		6 / 10 PHE A  87
THR A 101
LEU A 250
THR A 258
VAL A 301
VAL A 402
 None
HEM  A 501 ( 4.8A)
HEM  A 501 (-4.3A)
HEM  A 501 (-3.7A)
PEG  A 502 ( 4.5A)
None
 0.86A 1o76A-4dxyA:
52.3		 1o76A-4dxyA:
46.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1O76_B_CAMB1420_0
(CYTOCHROME P450-CAM)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		4 / 8 PHE A  87
LEU A 250
THR A 258
VAL A 301
 None
HEM  A 501 (-4.3A)
HEM  A 501 (-3.7A)
PEG  A 502 ( 4.5A)
 0.65A 1o76B-4dxyA:
52.2		 1o76B-4dxyA:
46.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1O76_B_CAMB1420_0
(CYTOCHROME P450-CAM)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		4 / 8 THR A 101
LEU A 250
THR A 258
VAL A 301
 HEM  A 501 ( 4.8A)
HEM  A 501 (-4.3A)
HEM  A 501 (-3.7A)
PEG  A 502 ( 4.5A)
 0.87A 1o76B-4dxyA:
52.2		 1o76B-4dxyA:
46.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1P2Y_A_NCTA440_1
(CYTOCHROME P450-CAM)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		4 / 7 PHE A  87
GLY A 254
ILE A 401
VAL A 402
 None
PEG  A 502 (-3.8A)
None
None
 0.78A 1p2yA-4dxyA:
51.5		 1p2yA-4dxyA:
46.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PHG_A_MYTA422_1
(CYTOCHROME P450-CAM)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		6 / 11 PHE A  87
GLY A 254
THR A 258
VAL A 301
ILE A 401
VAL A 402
 None
PEG  A 502 (-3.8A)
HEM  A 501 (-3.7A)
PEG  A 502 ( 4.5A)
None
None
 0.81A 1phgA-4dxyA:
52.0		 1phgA-4dxyA:
46.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PHG_A_MYTA422_1
(CYTOCHROME P450-CAM)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		6 / 11 PHE A  87
LEU A 250
GLY A 254
THR A 258
VAL A 301
ILE A 401
 None
HEM  A 501 (-4.3A)
PEG  A 502 (-3.8A)
HEM  A 501 (-3.7A)
PEG  A 502 ( 4.5A)
None
 1.06A 1phgA-4dxyA:
52.0		 1phgA-4dxyA:
46.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1T85_A_CAMA422_0
(CYTOCHROME P450-CAM)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		4 / 7 PHE A  87
THR A 101
LEU A 250
VAL A 301
 None
HEM  A 501 ( 4.8A)
HEM  A 501 (-4.3A)
PEG  A 502 ( 4.5A)
 1.01A 1t85A-4dxyA:
52.1		 1t85A-4dxyA:
46.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1T86_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		5 / 9 PHE A  87
THR A 101
LEU A 250
VAL A 301
VAL A 402
 None
HEM  A 501 ( 4.8A)
HEM  A 501 (-4.3A)
PEG  A 502 ( 4.5A)
None
 0.93A 1t86B-4dxyA:
52.0		 1t86B-4dxyA:
46.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1T87_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		4 / 7 PHE A  87
THR A 101
LEU A 250
VAL A 301
 None
HEM  A 501 ( 4.8A)
HEM  A 501 (-4.3A)
PEG  A 502 ( 4.5A)
 0.95A 1t87A-4dxyA:
52.0		 1t87A-4dxyA:
46.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1T88_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		4 / 7 PHE A  87
LEU A 250
GLY A 254
VAL A 301
 None
HEM  A 501 (-4.3A)
PEG  A 502 (-3.8A)
PEG  A 502 ( 4.5A)
 0.71A 1t88A-4dxyA:
51.9		 1t88A-4dxyA:
46.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1UYU_A_CAMA1416_0
(CYTOCHROME P450-CAM)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		4 / 8 PHE A  87
LEU A 250
THR A 258
VAL A 301
 None
HEM  A 501 (-4.3A)
HEM  A 501 (-3.7A)
PEG  A 502 ( 4.5A)
 0.71A 1uyuA-4dxyA:
52.3		 1uyuA-4dxyA:
46.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1UYU_A_CAMA1416_0
(CYTOCHROME P450-CAM)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		4 / 8 THR A 101
LEU A 250
THR A 258
VAL A 301
 HEM  A 501 ( 4.8A)
HEM  A 501 (-4.3A)
HEM  A 501 (-3.7A)
PEG  A 502 ( 4.5A)
 0.93A 1uyuA-4dxyA:
52.3		 1uyuA-4dxyA:
46.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YRC_A_CAMA420_0
(CYTOCHROME P450-CAM)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		4 / 7 PHE A  87
THR A 101
LEU A 250
VAL A 301
 None
HEM  A 501 ( 4.8A)
HEM  A 501 (-4.3A)
PEG  A 502 ( 4.5A)
 0.96A 1yrcA-4dxyA:
51.8		 1yrcA-4dxyA:
46.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YRD_A_CAMA420_0
(CYTOCHROME P450-CAM)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		4 / 7 PHE A  87
THR A 101
LEU A 250
VAL A 301
 None
HEM  A 501 ( 4.8A)
HEM  A 501 (-4.3A)
PEG  A 502 ( 4.5A)
 0.94A 1yrdA-4dxyA:
52.0		 1yrdA-4dxyA:
46.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A1M_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		4 / 7 PHE A  87
THR A 101
GLY A 254
THR A 258
 None
HEM  A 501 ( 4.8A)
PEG  A 502 (-3.8A)
HEM  A 501 (-3.7A)
 0.82A 2a1mA-4dxyA:
52.2		 2a1mA-4dxyA:
46.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A1M_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		4 / 8 PHE A  87
GLY A 254
THR A 258
VAL A 301
 None
PEG  A 502 (-3.8A)
HEM  A 501 (-3.7A)
PEG  A 502 ( 4.5A)
 0.41A 2a1mB-4dxyA:
52.3		 2a1mB-4dxyA:
46.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A1M_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		5 / 8 THR A 101
GLY A 254
THR A 258
VAL A 301
ILE A 401
 HEM  A 501 ( 4.8A)
PEG  A 502 (-3.8A)
HEM  A 501 (-3.7A)
PEG  A 502 ( 4.5A)
None
 0.76A 2a1mB-4dxyA:
52.3		 2a1mB-4dxyA:
46.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A1N_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		7 / 11 PHE A  87
THR A 101
LEU A 250
GLY A 254
THR A 258
VAL A 301
VAL A 402
 None
HEM  A 501 ( 4.8A)
HEM  A 501 (-4.3A)
PEG  A 502 (-3.8A)
HEM  A 501 (-3.7A)
PEG  A 502 ( 4.5A)
None
 0.94A 2a1nA-4dxyA:
51.8		 2a1nA-4dxyA:
45.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A1N_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		5 / 11 THR A 101
THR A 185
LEU A 250
GLY A 254
THR A 258
 HEM  A 501 ( 4.8A)
None
HEM  A 501 (-4.3A)
PEG  A 502 (-3.8A)
HEM  A 501 (-3.7A)
 0.89A 2a1nA-4dxyA:
51.8		 2a1nA-4dxyA:
45.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A1N_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		5 / 11 THR A 185
LEU A 250
GLY A 254
THR A 258
VAL A 402
 None
HEM  A 501 (-4.3A)
PEG  A 502 (-3.8A)
HEM  A 501 (-3.7A)
None
 1.19A 2a1nA-4dxyA:
51.8		 2a1nA-4dxyA:
45.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A1N_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		5 / 9 PHE A  87
THR A 101
LEU A 250
THR A 258
VAL A 301
 None
HEM  A 501 ( 4.8A)
HEM  A 501 (-4.3A)
HEM  A 501 (-3.7A)
PEG  A 502 ( 4.5A)
 0.95A 2a1nB-4dxyA:
52.2		 2a1nB-4dxyA:
45.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A1O_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		4 / 8 PHE A  87
LEU A 250
GLY A 254
VAL A 301
 None
HEM  A 501 (-4.3A)
PEG  A 502 (-3.8A)
PEG  A 502 ( 4.5A)
 0.60A 2a1oA-4dxyA:
52.1		 2a1oA-4dxyA:
45.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A1O_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		4 / 8 THR A 101
LEU A 250
GLY A 254
VAL A 301
 HEM  A 501 ( 4.8A)
HEM  A 501 (-4.3A)
PEG  A 502 (-3.8A)
PEG  A 502 ( 4.5A)
 0.77A 2a1oA-4dxyA:
52.1		 2a1oA-4dxyA:
45.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A1O_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		5 / 9 PHE A  87
THR A 101
GLY A 254
VAL A 301
ILE A 401
 None
HEM  A 501 ( 4.8A)
PEG  A 502 (-3.8A)
PEG  A 502 ( 4.5A)
None
 0.84A 2a1oB-4dxyA:
52.2		 2a1oB-4dxyA:
45.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A1O_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		5 / 9 PHE A  87
THR A 101
LEU A 250
GLY A 254
VAL A 301
 None
HEM  A 501 ( 4.8A)
HEM  A 501 (-4.3A)
PEG  A 502 (-3.8A)
PEG  A 502 ( 4.5A)
 0.89A 2a1oB-4dxyA:
52.2		 2a1oB-4dxyA:
45.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A7Q_A_CFBA328_2
(DEOXYCYTIDINE KINASE)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		4 / 4 ILE A 214
ASP A 224
LEU A 251
ARG A 238
 None
None
HEM  A 501 (-4.8A)
None
 1.37A 2a7qA-4dxyA:
undetectable		 2a7qA-4dxyA:
20.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2CP4_A_CAMA416_0
(CYTOCHROME P450-CAM)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		5 / 10 PHE A  87
THR A 101
LEU A 250
GLY A 254
VAL A 301
 None
HEM  A 501 ( 4.8A)
HEM  A 501 (-4.3A)
PEG  A 502 (-3.8A)
PEG  A 502 ( 4.5A)
 1.21A 2cp4A-4dxyA:
52.2		 2cp4A-4dxyA:
46.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2CP4_A_CAMA416_0
(CYTOCHROME P450-CAM)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		6 / 10 PHE A  87
THR A 101
LEU A 250
GLY A 254
VAL A 301
VAL A 402
 None
HEM  A 501 ( 4.8A)
HEM  A 501 (-4.3A)
PEG  A 502 (-3.8A)
PEG  A 502 ( 4.5A)
None
 0.88A 2cp4A-4dxyA:
52.2		 2cp4A-4dxyA:
46.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2FEU_A_CAMA1420_0
(CYTOCHROME P450-CAM)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		4 / 6 PHE A  87
THR A 101
LEU A 250
VAL A 301
 None
HEM  A 501 ( 4.8A)
HEM  A 501 (-4.3A)
PEG  A 502 ( 4.5A)
 0.98A 2feuA-4dxyA:
51.9		 2feuA-4dxyA:
46.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2FEU_B_CAMB1421_0
(CYTOCHROME P450-CAM)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		4 / 7 PHE A  87
THR A 101
LEU A 250
VAL A 301
 None
HEM  A 501 ( 4.8A)
HEM  A 501 (-4.3A)
PEG  A 502 ( 4.5A)
 1.00A 2feuB-4dxyA:
52.1		 2feuB-4dxyA:
46.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JJ8_C_AZZC1211_1
(DEOXYNUCLEOSIDE
KINASE)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		5 / 12 VAL A 259
LEU A 263
MET A 267
PHE A 266
ALA A 291
 HEM  A 501 ( 4.3A)
None
None
None
None
 1.28A 2jj8C-4dxyA:
undetectable		 2jj8C-4dxyA:
20.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2L8M_A_CAMA415_0
(CAMPHOR
5-MONOOXYGENASE)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		5 / 9 THR A 101
THR A 258
VAL A 301
ILE A 401
VAL A 402
 HEM  A 501 ( 4.8A)
HEM  A 501 (-3.7A)
PEG  A 502 ( 4.5A)
None
None
 0.67A 2l8mA-4dxyA:
48.5		 2l8mA-4dxyA:
46.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_A_SNLA1001_2
(MINERALOCORTICOID
RECEPTOR)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		4 / 5 LEU A 169
ALA A 165
LEU A 166
MET A 229
 None
 1.15A 2oaxA-4dxyA:
2.0		 2oaxA-4dxyA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OC8_A_HU5A999_1
(HEPATITIS C VIRUS)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		5 / 12 GLY A  37
PHE A 265
ALA A 404
ALA A 403
VAL A 402
 None
 0.97A 2oc8A-4dxyA:
undetectable		 2oc8A-4dxyA:
19.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QBM_A_CAMA517_0
(CYTOCHROME P450-CAM)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		4 / 8 PHE A  87
THR A 101
VAL A 301
ILE A 401
 None
HEM  A 501 ( 4.8A)
PEG  A 502 ( 4.5A)
None
 0.94A 2qbmA-4dxyA:
51.9		 2qbmA-4dxyA:
46.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QBN_A_CAMA442_0
(CYTOCHROME P450-CAM)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		4 / 7 PHE A  87
THR A 101
VAL A 301
VAL A 402
 None
HEM  A 501 ( 4.8A)
PEG  A 502 ( 4.5A)
None
 0.83A 2qbnA-4dxyA:
51.5		 2qbnA-4dxyA:
46.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QBO_A_CAMA442_0
(CYTOCHROME P450-CAM)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		5 / 10 PHE A  87
THR A 101
VAL A 301
ILE A 401
VAL A 402
 None
HEM  A 501 ( 4.8A)
PEG  A 502 ( 4.5A)
None
None
 0.81A 2qboA-4dxyA:
51.6		 2qboA-4dxyA:
46.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_C_KLNC1499_1
(CYTOCHROME P450 3A4)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		4 / 7 PHE A 298
PHE A 387
LEU A 377
ILE A 139
 None
 1.02A 2v0mC-4dxyA:
28.7		 2v0mC-4dxyA:
26.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Z97_A_CAMA422_0
(CYTOCHROME P450-CAM)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		4 / 6 THR A 101
LEU A 250
VAL A 301
VAL A 402
 HEM  A 501 ( 4.8A)
HEM  A 501 (-4.3A)
PEG  A 502 ( 4.5A)
None
 0.87A 2z97A-4dxyA:
52.3		 2z97A-4dxyA:
46.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZAX_A_CAMA422_0
(CYTOCHROME P450-CAM)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		4 / 7 PHE A  87
LEU A 250
THR A 258
VAL A 301
 None
HEM  A 501 (-4.3A)
HEM  A 501 (-3.7A)
PEG  A 502 ( 4.5A)
 0.85A 2zaxA-4dxyA:
52.0		 2zaxA-4dxyA:
46.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZUH_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		4 / 6 PHE A  87
THR A 101
LEU A 250
VAL A 301
 None
HEM  A 501 ( 4.8A)
HEM  A 501 (-4.3A)
PEG  A 502 ( 4.5A)
 0.84A 2zuhA-4dxyA:
52.1		 2zuhA-4dxyA:
46.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZUI_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		4 / 6 PHE A  87
THR A 101
LEU A 250
VAL A 301
 None
HEM  A 501 ( 4.8A)
HEM  A 501 (-4.3A)
PEG  A 502 ( 4.5A)
 0.98A 2zuiA-4dxyA:
52.0		 2zuiA-4dxyA:
46.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZWT_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		4 / 7 PHE A  87
THR A 101
LEU A 250
VAL A 301
 None
HEM  A 501 ( 4.8A)
HEM  A 501 (-4.3A)
PEG  A 502 ( 4.5A)
 0.98A 2zwtA-4dxyA:
52.0		 2zwtA-4dxyA:
46.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZWU_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		4 / 7 PHE A  87
THR A 101
LEU A 250
VAL A 301
 None
HEM  A 501 ( 4.8A)
HEM  A 501 (-4.3A)
PEG  A 502 ( 4.5A)
 0.97A 2zwuA-4dxyA:
52.0		 2zwuA-4dxyA:
46.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1009_1
(SERUM ALBUMIN)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		4 / 8 TYR A 154
SER A 141
VAL A 162
HIS A 161
 None
 1.18A 3b9lA-4dxyA:
1.9		 3b9lA-4dxyA:
21.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CPP_A_CAMA422_0
(CYTOCHROME P450-CAM)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		5 / 9 PHE A  87
THR A 101
LEU A 250
VAL A 301
VAL A 402
 None
HEM  A 501 ( 4.8A)
HEM  A 501 (-4.3A)
PEG  A 502 ( 4.5A)
None
 0.93A 3cppA-4dxyA:
52.0		 3cppA-4dxyA:
46.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FWF_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		4 / 7 PHE A  87
THR A 101
LEU A 250
VAL A 301
 None
HEM  A 501 ( 4.8A)
HEM  A 501 (-4.3A)
PEG  A 502 ( 4.5A)
 1.03A 3fwfA-4dxyA:
51.8		 3fwfA-4dxyA:
45.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FWF_B_CAMB420_0
(CAMPHOR
5-MONOOXYGENASE)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		4 / 7 PHE A  87
THR A 101
LEU A 250
VAL A 301
 None
HEM  A 501 ( 4.8A)
HEM  A 501 (-4.3A)
PEG  A 502 ( 4.5A)
 1.04A 3fwfB-4dxyA:
51.8		 3fwfB-4dxyA:
45.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FWG_B_CAMB420_0
(CAMPHOR
5-MONOOXYGENASE)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		4 / 7 PHE A  87
LEU A 250
THR A 258
VAL A 301
 None
HEM  A 501 (-4.3A)
HEM  A 501 (-3.7A)
PEG  A 502 ( 4.5A)
 0.78A 3fwgB-4dxyA:
52.0		 3fwgB-4dxyA:
46.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FWI_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		5 / 7 PHE A  87
THR A 101
LEU A 250
THR A 258
VAL A 301
 None
HEM  A 501 ( 4.8A)
HEM  A 501 (-4.3A)
HEM  A 501 (-3.7A)
PEG  A 502 ( 4.5A)
 1.04A 3fwiA-4dxyA:
51.6		 3fwiA-4dxyA:
45.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FWJ_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		4 / 7 PHE A  87
THR A 101
LEU A 250
VAL A 301
 None
HEM  A 501 ( 4.8A)
HEM  A 501 (-4.3A)
PEG  A 502 ( 4.5A)
 1.01A 3fwjA-4dxyA:
51.9		 3fwjA-4dxyA:
45.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G4L_A_ROFA901_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		3 / 3 ASP A 173
LEU A 177
GLN A 183
 None
 0.77A 3g4lA-4dxyA:
undetectable		 3g4lA-4dxyA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GGU_B_017B201_1
(PROTEASE)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		5 / 12 LEU A 250
GLY A 365
ALA A 364
GLY A 357
THR A 101
 HEM  A 501 (-4.3A)
HEM  A 501 (-3.4A)
HEM  A 501 ( 3.9A)
HEM  A 501 (-3.9A)
HEM  A 501 ( 4.8A)
 0.96A 3gguA-4dxyA:
undetectable		 3gguA-4dxyA:
14.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GGU_B_017B201_2
(PROTEASE)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		5 / 9 LEU A 250
GLY A 365
ALA A 364
GLY A 357
THR A 101
 HEM  A 501 (-4.3A)
HEM  A 501 (-3.4A)
HEM  A 501 ( 3.9A)
HEM  A 501 (-3.9A)
HEM  A 501 ( 4.8A)
 0.97A 3gguB-4dxyA:
undetectable		 3gguB-4dxyA:
14.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LXI_A_CAMA423_0
(CYTOCHROME P450)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		6 / 10 THR A 101
LEU A 250
GLY A 254
THR A 258
VAL A 301
VAL A 402
 HEM  A 501 ( 4.8A)
HEM  A 501 (-4.3A)
PEG  A 502 (-3.8A)
HEM  A 501 (-3.7A)
PEG  A 502 ( 4.5A)
None
 0.77A 3lxiA-4dxyA:
55.4		 3lxiA-4dxyA:
61.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LXI_A_CAMA423_0
(CYTOCHROME P450)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		5 / 10 THR A 101
LEU A 250
LEU A 253
GLY A 254
THR A 258
 HEM  A 501 ( 4.8A)
HEM  A 501 (-4.3A)
None
PEG  A 502 (-3.8A)
HEM  A 501 (-3.7A)
 0.79A 3lxiA-4dxyA:
55.4		 3lxiA-4dxyA:
61.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LXI_A_CAMA423_0
(CYTOCHROME P450)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		5 / 10 THR A 185
LEU A 250
LEU A 253
GLY A 254
THR A 258
 None
HEM  A 501 (-4.3A)
None
PEG  A 502 (-3.8A)
HEM  A 501 (-3.7A)
 0.97A 3lxiA-4dxyA:
55.4		 3lxiA-4dxyA:
61.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LXI_B_CAMB423_0
(CYTOCHROME P450)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		6 / 11 THR A 101
LEU A 250
GLY A 254
THR A 258
VAL A 301
VAL A 402
 HEM  A 501 ( 4.8A)
HEM  A 501 (-4.3A)
PEG  A 502 (-3.8A)
HEM  A 501 (-3.7A)
PEG  A 502 ( 4.5A)
None
 0.81A 3lxiB-4dxyA:
54.9		 3lxiB-4dxyA:
61.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LXI_B_CAMB423_0
(CYTOCHROME P450)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		5 / 11 THR A 101
LEU A 250
LEU A 253
GLY A 254
THR A 258
 HEM  A 501 ( 4.8A)
HEM  A 501 (-4.3A)
None
PEG  A 502 (-3.8A)
HEM  A 501 (-3.7A)
 0.78A 3lxiB-4dxyA:
54.9		 3lxiB-4dxyA:
61.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WRH_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		4 / 7 PHE A  87
THR A 101
LEU A 250
VAL A 301
 None
HEM  A 501 ( 4.8A)
HEM  A 501 (-4.3A)
PEG  A 502 ( 4.5A)
 0.98A 3wrhA-4dxyA:
52.2		 3wrhA-4dxyA:
46.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WRI_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		4 / 5 GLY A 254
THR A 258
ILE A 401
VAL A 402
 PEG  A 502 (-3.8A)
HEM  A 501 (-3.7A)
None
None
 0.43A 3wriA-4dxyA:
54.9		 3wriA-4dxyA:
46.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WRI_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		4 / 5 LEU A 250
GLY A 254
THR A 258
VAL A 402
 HEM  A 501 (-4.3A)
PEG  A 502 (-3.8A)
HEM  A 501 (-3.7A)
None
 0.59A 3wriA-4dxyA:
54.9		 3wriA-4dxyA:
46.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WRI_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		4 / 5 GLY A 254
THR A 258
ILE A 401
VAL A 402
 PEG  A 502 (-3.8A)
HEM  A 501 (-3.7A)
None
None
 0.42A 3wriB-4dxyA:
54.9		 3wriB-4dxyA:
46.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WRI_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		4 / 5 LEU A 250
GLY A 254
THR A 258
VAL A 402
 HEM  A 501 (-4.3A)
PEG  A 502 (-3.8A)
HEM  A 501 (-3.7A)
None
 0.58A 3wriB-4dxyA:
54.9		 3wriB-4dxyA:
46.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WRJ_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		4 / 7 PHE A  87
THR A 101
LEU A 250
VAL A 301
 None
HEM  A 501 ( 4.8A)
HEM  A 501 (-4.3A)
PEG  A 502 ( 4.5A)
 1.00A 3wrjA-4dxyA:
52.2		 3wrjA-4dxyA:
46.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WRK_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		5 / 5 PHE A  87
LEU A 250
GLY A 254
ILE A 401
VAL A 402
 None
HEM  A 501 (-4.3A)
PEG  A 502 (-3.8A)
None
None
 0.62A 3wrkA-4dxyA:
53.9		 3wrkA-4dxyA:
46.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WRK_D_CAMD502_0
(CAMPHOR
5-MONOOXYGENASE)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		5 / 5 PHE A  87
LEU A 250
GLY A 254
THR A 258
VAL A 301
 None
HEM  A 501 (-4.3A)
PEG  A 502 (-3.8A)
HEM  A 501 (-3.7A)
PEG  A 502 ( 4.5A)
 1.47A 3wrkD-4dxyA:
54.0		 3wrkD-4dxyA:
46.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WRK_D_CAMD502_0
(CAMPHOR
5-MONOOXYGENASE)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		5 / 5 PHE A  87
LEU A 250
GLY A 254
THR A 258
VAL A 402
 None
HEM  A 501 (-4.3A)
PEG  A 502 (-3.8A)
HEM  A 501 (-3.7A)
None
 0.54A 3wrkD-4dxyA:
54.0		 3wrkD-4dxyA:
46.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WRL_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		4 / 7 PHE A  87
THR A 101
LEU A 250
VAL A 301
 None
HEM  A 501 ( 4.8A)
HEM  A 501 (-4.3A)
PEG  A 502 ( 4.5A)
 0.99A 3wrlA-4dxyA:
52.1		 3wrlA-4dxyA:
46.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WRM_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		4 / 7 PHE A  87
THR A 101
LEU A 250
VAL A 301
 None
HEM  A 501 ( 4.8A)
HEM  A 501 (-4.3A)
PEG  A 502 ( 4.5A)
 1.01A 3wrmA-4dxyA:
52.1		 3wrmA-4dxyA:
46.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WRM_F_CAMF503_0
(CAMPHOR
5-MONOOXYGENASE)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		4 / 7 PHE A  87
THR A 101
LEU A 250
VAL A 301
 None
HEM  A 501 ( 4.8A)
HEM  A 501 (-4.3A)
PEG  A 502 ( 4.5A)
 1.03A 3wrmF-4dxyA:
52.1		 3wrmF-4dxyA:
46.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4C9K_A_CAMA424_0
(CYTOCHROME P450)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		5 / 9 THR A 101
LEU A 250
GLY A 254
THR A 258
VAL A 301
 HEM  A 501 ( 4.8A)
HEM  A 501 (-4.3A)
PEG  A 502 (-3.8A)
HEM  A 501 (-3.7A)
PEG  A 502 ( 4.5A)
 0.93A 4c9kA-4dxyA:
55.5		 4c9kA-4dxyA:
61.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4C9K_A_CAMA424_0
(CYTOCHROME P450)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		5 / 9 THR A 101
THR A 185
LEU A 250
GLY A 254
THR A 258
 HEM  A 501 ( 4.8A)
None
HEM  A 501 (-4.3A)
PEG  A 502 (-3.8A)
HEM  A 501 (-3.7A)
 1.12A 4c9kA-4dxyA:
55.5		 4c9kA-4dxyA:
61.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4C9K_A_CAMA424_0
(CYTOCHROME P450)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		5 / 9 THR A 101
THR A 185
LEU A 250
LEU A 253
GLY A 254
 HEM  A 501 ( 4.8A)
None
HEM  A 501 (-4.3A)
None
PEG  A 502 (-3.8A)
 1.17A 4c9kA-4dxyA:
55.5		 4c9kA-4dxyA:
61.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4C9K_B_CAMB424_0
(CYTOCHROME P450)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		5 / 9 LEU A 250
GLY A 254
THR A 258
VAL A 301
VAL A 402
 HEM  A 501 (-4.3A)
PEG  A 502 (-3.8A)
HEM  A 501 (-3.7A)
PEG  A 502 ( 4.5A)
None
 0.94A 4c9kB-4dxyA:
55.2		 4c9kB-4dxyA:
61.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4C9K_B_CAMB424_0
(CYTOCHROME P450)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		5 / 9 THR A 185
LEU A 250
LEU A 253
GLY A 254
THR A 258
 None
HEM  A 501 (-4.3A)
None
PEG  A 502 (-3.8A)
HEM  A 501 (-3.7A)
 1.01A 4c9kB-4dxyA:
55.2		 4c9kB-4dxyA:
61.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4C9L_A_CAMA1419_0
(CYTOCHROME P450)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		8 / 12 ILE A  86
THR A 101
LEU A 250
GLY A 254
THR A 258
VAL A 301
ILE A 401
VAL A 402
 None
HEM  A 501 ( 4.8A)
HEM  A 501 (-4.3A)
PEG  A 502 (-3.8A)
HEM  A 501 (-3.7A)
PEG  A 502 ( 4.5A)
None
None
 0.70A 4c9lA-4dxyA:
55.7		 4c9lA-4dxyA:
61.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4C9L_A_CAMA1419_0
(CYTOCHROME P450)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		6 / 12 THR A 101
THR A 185
LEU A 250
LEU A 253
GLY A 254
THR A 258
 HEM  A 501 ( 4.8A)
None
HEM  A 501 (-4.3A)
None
PEG  A 502 (-3.8A)
HEM  A 501 (-3.7A)
 1.22A 4c9lA-4dxyA:
55.7		 4c9lA-4dxyA:
61.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4C9L_B_CAMB1419_0
(CYTOCHROME P450)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		5 / 12 GLY A 255
THR A 258
VAL A 301
ILE A 401
VAL A 402
 HEM  A 501 (-3.3A)
HEM  A 501 (-3.7A)
PEG  A 502 ( 4.5A)
None
None
 0.86A 4c9lB-4dxyA:
55.4		 4c9lB-4dxyA:
61.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4C9L_B_CAMB1419_0
(CYTOCHROME P450)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		8 / 12 ILE A  86
THR A 101
LEU A 250
GLY A 254
THR A 258
VAL A 301
ILE A 401
VAL A 402
 None
HEM  A 501 ( 4.8A)
HEM  A 501 (-4.3A)
PEG  A 502 (-3.8A)
HEM  A 501 (-3.7A)
PEG  A 502 ( 4.5A)
None
None
 0.68A 4c9lB-4dxyA:
55.4		 4c9lB-4dxyA:
61.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4C9L_B_CAMB1419_0
(CYTOCHROME P450)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		6 / 12 THR A 101
THR A 185
LEU A 250
LEU A 253
GLY A 254
THR A 258
 HEM  A 501 ( 4.8A)
None
HEM  A 501 (-4.3A)
None
PEG  A 502 (-3.8A)
HEM  A 501 (-3.7A)
 1.22A 4c9lB-4dxyA:
55.4		 4c9lB-4dxyA:
61.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4C9N_B_CAMB1420_0
(CYTOCHROME P450)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		5 / 10 THR A 101
LEU A 250
GLY A 254
VAL A 301
VAL A 402
 HEM  A 501 ( 4.8A)
HEM  A 501 (-4.3A)
PEG  A 502 (-3.8A)
PEG  A 502 ( 4.5A)
None
 0.76A 4c9nB-4dxyA:
55.0		 4c9nB-4dxyA:
61.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4C9O_A_CAMA423_0
(CYTOCHROME P450)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		8 / 12 ILE A  86
THR A 101
LEU A 250
GLY A 254
THR A 258
VAL A 301
ILE A 401
VAL A 402
 None
HEM  A 501 ( 4.8A)
HEM  A 501 (-4.3A)
PEG  A 502 (-3.8A)
HEM  A 501 (-3.7A)
PEG  A 502 ( 4.5A)
None
None
 0.76A 4c9oA-4dxyA:
55.3		 4c9oA-4dxyA:
61.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4C9O_B_CAMB423_0
(CYTOCHROME P450)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		8 / 12 ILE A  86
THR A 101
LEU A 250
GLY A 254
THR A 258
VAL A 301
ILE A 401
VAL A 402
 None
HEM  A 501 ( 4.8A)
HEM  A 501 (-4.3A)
PEG  A 502 (-3.8A)
HEM  A 501 (-3.7A)
PEG  A 502 ( 4.5A)
None
None
 0.77A 4c9oB-4dxyA:
55.0		 4c9oB-4dxyA:
61.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4C9P_A_CAMA423_0
(CYTOCHROME P450)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		5 / 9 THR A 101
LEU A 250
GLY A 254
VAL A 301
VAL A 402
 HEM  A 501 ( 4.8A)
HEM  A 501 (-4.3A)
PEG  A 502 (-3.8A)
PEG  A 502 ( 4.5A)
None
 0.69A 4c9pA-4dxyA:
55.7		 4c9pA-4dxyA:
61.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4C9P_A_CAMA423_0
(CYTOCHROME P450)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		5 / 9 THR A 101
THR A 185
LEU A 250
LEU A 253
GLY A 254
 HEM  A 501 ( 4.8A)
None
HEM  A 501 (-4.3A)
None
PEG  A 502 (-3.8A)
 1.13A 4c9pA-4dxyA:
55.7		 4c9pA-4dxyA:
61.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4C9P_B_CAMB423_0
(CYTOCHROME P450)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		5 / 10 THR A 101
LEU A 250
GLY A 254
VAL A 301
VAL A 402
 HEM  A 501 ( 4.8A)
HEM  A 501 (-4.3A)
PEG  A 502 (-3.8A)
PEG  A 502 ( 4.5A)
None
 0.66A 4c9pB-4dxyA:
55.2		 4c9pB-4dxyA:
61.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4C9P_B_CAMB423_0
(CYTOCHROME P450)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		5 / 10 THR A 101
THR A 185
LEU A 250
LEU A 253
GLY A 254
 HEM  A 501 ( 4.8A)
None
HEM  A 501 (-4.3A)
None
PEG  A 502 (-3.8A)
 1.15A 4c9pB-4dxyA:
55.2		 4c9pB-4dxyA:
61.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CP4_A_CAMA416_0
(CYTOCHROME P450-CAM)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		4 / 7 PHE A  87
LEU A 250
VAL A 301
VAL A 402
 None
HEM  A 501 (-4.3A)
PEG  A 502 ( 4.5A)
None
 0.78A 4cp4A-4dxyA:
52.0		 4cp4A-4dxyA:
46.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EK1_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		5 / 9 PHE A  87
THR A 101
LEU A 250
VAL A 301
VAL A 402
 None
HEM  A 501 ( 4.8A)
HEM  A 501 (-4.3A)
PEG  A 502 ( 4.5A)
None
 0.87A 4ek1B-4dxyA:
52.3		 4ek1B-4dxyA:
46.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IJI_H_BEZH501_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN YIBF)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		4 / 7 ASN A 120
ALA A 122
VAL A 127
ARG A 125
 None
 1.12A 4ijiH-4dxyA:
undetectable		 4ijiH-4dxyA:
22.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4JX1_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		7 / 10 PHE A  87
THR A 101
GLY A 254
THR A 258
VAL A 301
ILE A 401
VAL A 402
 None
HEM  A 501 ( 4.8A)
PEG  A 502 (-3.8A)
HEM  A 501 (-3.7A)
PEG  A 502 ( 4.5A)
None
None
 0.59A 4jx1B-4dxyA:
56.5		 4jx1B-4dxyA:
46.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4JX1_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		7 / 10 PHE A  87
THR A 101
LEU A 250
GLY A 254
THR A 258
VAL A 301
VAL A 402
 None
HEM  A 501 ( 4.8A)
HEM  A 501 (-4.3A)
PEG  A 502 (-3.8A)
HEM  A 501 (-3.7A)
PEG  A 502 ( 4.5A)
None
 0.67A 4jx1B-4dxyA:
56.5		 4jx1B-4dxyA:
46.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4L4A_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		4 / 8 PHE A  87
THR A 101
LEU A 250
VAL A 301
 None
HEM  A 501 ( 4.8A)
HEM  A 501 (-4.3A)
PEG  A 502 ( 4.5A)
 0.90A 4l4aA-4dxyA:
52.1		 4l4aA-4dxyA:
46.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_A_SPMA201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		4 / 8 MET A 306
GLU A  84
GLU A  94
TYR A 111
 PEG  A 504 ( 3.8A)
PEG  A 504 (-4.0A)
None
None
 1.20A 4mj8A-4dxyA:
undetectable
4mj8C-4dxyA:
undetectable		 4mj8A-4dxyA:
16.67
4mj8C-4dxyA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1E_A_C2FA3000_1
(DIHYDROPTEROATE
SYNTHASE DHPS)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		3 / 3 LYS A 314
ASN A  17
ASP A  52
 None
 0.65A 4o1eA-4dxyA:
undetectable		 4o1eA-4dxyA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OK1_A_198A1001_2
(ANDROGEN RECEPTOR)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		4 / 8 LEU A 381
LEU A 276
HIS A 273
ILE A 268
 None
None
PEG  A 506 (-3.7A)
None
 1.05A 4ok1A-4dxyA:
2.4		 4ok1A-4dxyA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1X_A_017A101_2
(ASPARTYL PROTEASE)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		5 / 12 LEU A 325
ASP A  52
ILE A  54
ILE A  50
ILE A  64
 None
 0.91A 4q1xB-4dxyA:
undetectable		 4q1xB-4dxyA:
13.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_J_377J401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		4 / 6 ASN A  67
GLU A  73
TYR A 313
LEU A  53
 None
 1.26A 4twdI-4dxyA:
undetectable
4twdJ-4dxyA:
undetectable		 4twdI-4dxyA:
22.43
4twdJ-4dxyA:
22.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CP4_A_CAMA422_0
(CYTOCHROME P450CAM)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		6 / 9 PHE A  87
LEU A 250
GLY A 254
THR A 258
VAL A 301
VAL A 402
 None
HEM  A 501 (-4.3A)
PEG  A 502 (-3.8A)
HEM  A 501 (-3.7A)
PEG  A 502 ( 4.5A)
None
 0.89A 5cp4A-4dxyA:
52.2		 5cp4A-4dxyA:
46.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IK1_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		4 / 5 PHE A  87
LEU A 250
GLY A 254
ILE A 401
 None
HEM  A 501 (-4.3A)
PEG  A 502 (-3.8A)
None
 0.35A 5ik1A-4dxyA:
55.3		 5ik1A-4dxyA:
46.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYE_B_TA1B502_1
(TUBULIN BETA CHAIN)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		5 / 12 GLU A  84
VAL A  85
LEU A  53
ALA A 304
GLY A  60
 PEG  A 504 (-4.0A)
None
None
None
None
 1.26A 5syeB-4dxyA:
undetectable		 5syeB-4dxyA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC3_A_486A801_2
(GLUCOCORTICOID
RECEPTOR)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		4 / 5 LEU A 252
LEU A 256
GLN A 245
TYR A 207
 None
 1.39A 5uc3A-4dxyA:
2.7		 5uc3A-4dxyA:
11.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UXD_B_ZITB501_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E MPHH)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		5 / 12 ILE A 124
VAL A 162
PHE A 262
PHE A 266
GLY A 290
 None
None
HEM  A 501 (-4.4A)
None
None
 0.89A 5uxdB-4dxyA:
undetectable		 5uxdB-4dxyA:
21.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WK9_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		4 / 7 PHE A  87
THR A 101
LEU A 250
VAL A 301
 None
HEM  A 501 ( 4.8A)
HEM  A 501 (-4.3A)
PEG  A 502 ( 4.5A)
 1.05A 5wk9A-4dxyA:
52.8		 5wk9A-4dxyA:
45.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_C_SUEC1203_0
(NS3 PROTEASE)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		5 / 12 GLY A  37
PHE A 265
ALA A 404
ALA A 403
VAL A 402
 None
 0.96A 6c2mC-4dxyA:
undetectable		 6c2mC-4dxyA:
11.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6CP4_A_CAMA422_0
(CYTOCHROME P450CAM)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		4 / 8 PHE A  87
LEU A 250
THR A 258
VAL A 301
 None
HEM  A 501 (-4.3A)
HEM  A 501 (-3.7A)
PEG  A 502 ( 4.5A)
 0.84A 6cp4A-4dxyA:
51.8		 6cp4A-4dxyA:
46.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6CP4_A_CAMA422_0
(CYTOCHROME P450CAM)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		4 / 8 PHE A  87
THR A 258
VAL A 301
VAL A 402
 None
HEM  A 501 (-3.7A)
PEG  A 502 ( 4.5A)
None
 0.66A 6cp4A-4dxyA:
51.8		 6cp4A-4dxyA:
46.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DYO_A_LDPA901_0
(EBONY)		 4dxy CYTOCHROME P450
(Novosphingobium
aromaticivorans) 		4 / 5 GLU A 156
VAL A 260
LEU A 256
THR A 185
 None
 1.37A 6dyoA-4dxyA:
undetectable		 6dyoA-4dxyA:
12.39