SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4dy5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_I_ASDI1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 4dy5 GIFSY-1 PROPHAGE
PROTEIN
(Salmonella
enterica) 		5 / 9 LEU A  75
ALA A 103
LEU A 101
ALA A  56
PHE A  54
 None
 1.19A 2vcvI-4dy5A:
undetectable		 2vcvI-4dy5A:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA505_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 4dy5 GIFSY-1 PROPHAGE
PROTEIN
(Salmonella
enterica) 		3 / 3 THR A  51
ASN A  26
GLU A 108
 None
 0.54A 3v4tA-4dy5A:
undetectable
3v4tC-4dy5A:
undetectable		 3v4tA-4dy5A:
12.95
3v4tC-4dy5A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1G_B_LNLB701_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4dy5 GIFSY-1 PROPHAGE
PROTEIN
(Salmonella
enterica) 		4 / 7 VAL A 128
VAL A  64
ASN A  26
VAL A  84
 None
 0.94A 4e1gB-4dy5A:
undetectable		 4e1gB-4dy5A:
12.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQY_B_017B101_2
(PROTEASE E35D-DRV)		 4dy5 GIFSY-1 PROPHAGE
PROTEIN
(Salmonella
enterica) 		4 / 7 ASN A  68
GLY A  70
ALA A  71
ASP A  72
 None
None
None
GOL  A 202 (-3.1A)
 0.62A 5kqyB-4dy5A:
undetectable		 5kqyB-4dy5A:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR1_B_017B101_2
(PROTEASE PR5-DRV)		 4dy5 GIFSY-1 PROPHAGE
PROTEIN
(Salmonella
enterica) 		4 / 8 ASN A  68
GLY A  70
ALA A  71
ASP A  72
 None
None
None
GOL  A 202 (-3.1A)
 0.60A 5kr1B-4dy5A:
undetectable		 5kr1B-4dy5A:
19.69